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  3. Tagrisso 80Mg Tablet 10'S

Tagrisso 80Mg Tablet 10'S, Pack of 10 TabletS
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Composition :

OSIMERTINIB-80MG

Manufacturer/Marketer :

Astra Zeneca Pharma India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tagrisso 80Mg Tablet

Tagrisso 80Mg Tablet belongs to a class of protein kinase inhibitors primarily used to manage or treat lung cancer. Lung cancer is a disease that causes malignant (cancer) cells to grow in lung tissues.

Tagrisso 80Mg Tablet contains Osimertinib, which blocks proteins on cancer cells that encourage cancer growth. Thus, it reduces or stops the progression of advanced cancer.

To treat your condition effectually, continue using Tagrisso 80Mg Tablet for as long as your doctor has prescribed it. The most common adverse reactions are diarrhoea, rash, dry skin, nail toxicity, stomatitis (inflammation of the oral mucosa), fatigue (feeling overtired), decreased appetite, and low blood cell counts. You should talk to your doctor if you persistently experience these side effects.

Before taking the Tagrisso 80Mg Tablet , inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. Tagrisso 80Mg Tablet can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on therapy with Tagrisso 80Mg Tablet . Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Uses of Tagrisso 80Mg Tablet

Treatment of Lung Cancer

Directions for Use

Tagrisso 80Mg Tablet should be swallowed as a whole with a glass of water. Do not crush, chew, or break the tablets. The doctor determines the dose and duration of the treatment based on your health condition.

Medicinal Benefits

Tagrisso 80Mg Tablet contains Osimertinib, which belongs to a class of protein kinase inhibitors primarily used to manage or treat lung cancer. Osimertinib blocks proteins in cancer cells that encourage the cancer to grow. Osimertinib can temporarily reduce or stop the progression of advanced cancer. Following surgery, Osimertinib may help prevent the cancer from returning.

How Tagrisso 80Mg Tablet Works

Tagrisso 80Mg Tablet contains Osimertinib, which blocks proteins on cancer cells that encourage cancer growth. Thus, it reduces or stops the progression of advanced cancer.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tagrisso 80Mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.
  • Soak the infected nail in warm water for 10 to 20 minutes, a few times a day.
  • Apply topical antibiotic ointment as advised by the doctor.
  • Avoid irritants and excessive moisture.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Consult a hematologist or doctor to identify the cause of thrombocytopenia (Decreased Platelet Count) and plan treatment.
  • Foods rich in vitamins B12, C, folate, and iron may help boost platelet count.
  • Avoid heavy lifting, bending, or straining to reduce bleeding risk.
  • Stay hydrated by drinking plenty of water to help prevent bleeding.
  • Avoid alcohol and tobacco to prevent lowering platelet count and reduce bleeding risk.
  • Regular blood tests help monitor platelet count and detect any changes.

What if I have taken an overdose of Tagrisso 80Mg Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Tagrisso 80Mg Tablet or observe any side effects, please go to the emergency department of the closest hospital or nursing home.

Drug Warnings

Before taking the Tagrisso 80Mg Tablet , inform your doctor about all your medical conditions, sensitivities, and medications you are using. Exposure of an unborn child to this medication could cause birth defects, so you should not become pregnant or father a child while on this medication. Effective birth control is required throughout treatment and at least six weeks after treatment for women and four months after treatment for males. You should not breastfeed while taking this medication for two weeks after your last dose. Unless the doctor suggests, do not use any other medicine, including herbal or vitamin supplements. In rare cases, Tagrisso 80Mg Tablet therapy may lead to Interstitial lung disease (ILD)/Pneumonitis. Dyspnea, cough, and fever are the symptoms which may be indicative of ILD. If these symptoms worsen, contact your doctor right away. If ILD is confirmed, your doctor will discontinue the Tagrisso 80Mg Tablet therapy.

Drug-Drug Interactions

verifiedApollotooltip
OsimertinibItraconazole
Severe
OsimertinibEtanercept
Severe

Drug-Drug Interactions

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OsimertinibItraconazole
Severe
How does the drug interact with Tagrisso 80Mg Tablet:
Tagrisso 80Mg Tablet's blood levels may rise if itraconazole and Tagrisso 80Mg Tablet are taken together.

How to manage the interaction:
Tagrisso 80Mg Tablet and itraconazole may interact, but if a doctor prescribes them, you can still use them. If you develop vomiting, diarrhoea, mouth sores, lightheadedness, fainting, shortness of breath, swelling, or a racing heart, contact a doctor. Never discontinue taking a medication without consulting a doctor.
OsimertinibEtanercept
Severe
How does the drug interact with Tagrisso 80Mg Tablet:
When Etanercept is used with Tagrisso 80Mg Tablet, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with Tagrisso 80Mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
OsimertinibVenlafaxine
Severe
How does the drug interact with Tagrisso 80Mg Tablet:
Taking Venlafaxine with Tagrisso 80Mg Tablet increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Venlafaxine with Tagrisso 80Mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, consult your doctor immediately if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
OsimertinibAmitriptyline
Severe
How does the drug interact with Tagrisso 80Mg Tablet:
Coadministration of Amitriptyline and Tagrisso 80Mg Tablet may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amitriptyline with Tagrisso 80Mg Tablet may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
OsimertinibFluconazole
Severe
How does the drug interact with Tagrisso 80Mg Tablet:
Taking Fluconazole with Tagrisso 80Mg Tablet may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, fluconazole can be taken with Tagrisso 80Mg Tablet if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not Discontinue the medications without consulting a doctor.
OsimertinibOxytocin
Severe
How does the drug interact with Tagrisso 80Mg Tablet:
Using Tagrisso 80Mg Tablet together with oxytocin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Oxytocin with Tagrisso 80Mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience if you develop sudden dizziness, lightheadedness, fainting, shortness of breath contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
OsimertinibAdenosine
Severe
How does the drug interact with Tagrisso 80Mg Tablet:
Using Tagrisso 80Mg Tablet with Adenosine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Adenosine with Tagrisso 80Mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on your qt interval. If you experience shortness of breath, palpitations, chest discomfort, or dizziness, contact a doctor right away. Do not stop using any medications without a doctor's advice.
OsimertinibLeuprorelin
Severe
How does the drug interact with Tagrisso 80Mg Tablet:
Taking leuprorelin and Tagrisso 80Mg Tablet together can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking leuprorelin and Tagrisso 80Mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience prolonged diarrhea, vomiting, dizziness, lightheadedness, fainting, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
OsimertinibNortriptyline
Severe
How does the drug interact with Tagrisso 80Mg Tablet:
Coadministration of Nortriptyline with Tagrisso 80Mg Tablet can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nortriptyline with Tagrisso 80Mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
OsimertinibAlfuzosin
Severe
How does the drug interact with Tagrisso 80Mg Tablet:
Taking Tagrisso 80Mg Tablet and Alfuzosin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Tagrisso 80Mg Tablet and Alfuzosin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

KINASE INHIBITORS
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Tagrisso 80Mg Tablet .

bannner image

Pregnancy

Unsafe

Tagrisso 80Mg Tablet should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Unsafe

You should not breastfeed for two weeks after your last dose while taking this medication.

bannner image

Driving

Caution

Tagrisso 80Mg Tablet may cause fatigue (feeling overtired), impacting the ability to drive or use machines.

bannner image

Liver

Caution

Tagrisso 80Mg Tablet should be used with caution if you have liver disease. Inform your doctor before taking the Tagrisso 80Mg Tablet if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Tagrisso 80Mg Tablet should be used with caution if you have kidney disease. Inform your doctor before taking the Tagrisso 80Mg Tablet if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

Safety and effectiveness in patients below the age of 18 years have not been established. Hence, use is not recommended.

Have a query?

FAQs

Tagrisso 80Mg Tablet is used to treat Lung cancer.

Tagrisso 80Mg Tablet contains Osimertinib, a protein kinase inhibitor that works by blocking the abnormal protein which can cause uncontrolled cell growth and cancer; thus, it slows or stops cancer growth.

While taking Tagrisso 80Mg Tablet , visit your doctor at all the appointments to ensure treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Tagrisso 80Mg Tablet .

This medicine may reduce the quantity of platelets in your blood significantly. Platelets are cells that aid in the clotting of blood. If your platelet count is low, you may bruise or bleed easily. Inform your doctor if you experience any unexplained bruises or bleeding. You may require a drip to receive more platelets. This is referred to as a platelet transfusion.

Tagrisso 80Mg Tablet may cause infertility. Discuss with your doctor all the risks of taking this medication.

Non-small cell lung cancer (NSCLC) is common type of lung cancer. It accounts for about 80-85% of all lung cancers. Lung cancer, in general, is the second most common cancer in both men and women, and Non-small cell lung cancer (NSCLC) is the most prevalent type.

Non-small cell lung cancer (NSCLC) is a type of lung cancer that begins at the cellular level and causes abnormal cells in the lungs to reproduce rapidly and out of control.

The common side effects of Tagrisso 80Mg Tablet are diarrhoea, rash, dry skin, nail toxicity, stomatitis (inflammation of the oral mucosa), fatigue (feeling overtired), decreased appetite (hunger), and low blood cell counts. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Other Info - TAG0030

Disclaimer

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 9:32 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.astrazeneca.com/media-centre/press-releases/2016/tagrisso-osimertinib-approved-in-eu-as-first-in-class-treatment-for-lung-cancer-03022016.html#
  2. https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/osimertinib
  3. https://www.oncolink.org/cancer-treatment/oncolink-rx/osimertinib-tagrisso-r
  4. https://www.mskcc.org/cancer-care/patient-education/medications/adult/osimertinib
  5. https://reference.medscape.com/drug/tagrisso-osimertinib-1000062
  6. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/osimertinib
  7. https://medlineplus.gov/druginfo/meds/a616005.html
  8. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208065s008lbl.pdf
  9. https://www.drugs.com/drug-interactions/osimertinib.html

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