If you are allergic to Nilotinib or any other medicines, please tell your doctor. Avoid taking Tasigna 150Mg Capsule if you are pregnant or breastfeeding. You are recommended to use effective contraceptive methods while taking Tasigna 150Mg Capsule and for two weeks after completing the course of Tasigna 150Mg Capsule. Tasigna 150Mg Capsule is not recommended for children below one year of age. Tasigna 150Mg Capsule may affect the growth and development of children with chronic phase Ph+ CML. Some children and adolescents may have slower than normal growth while taking Tasigna 150Mg Capsule. Therefore, your doctor will monitor the growth of your child at regular visits. Drive only if you are alert as Tasigna 150Mg Capsule may cause dizziness or visual disorders as side effects in some people. Tasigna 150Mg Capsule may increase the risk of liver problems, especially in people with a history of liver problems. Therefore, if you have yellow skin and eyes, dark-coloured urine, or stomach pain while taking Tasigna 150Mg Capsule, contact your doctor immediately, as these might be symptoms of liver problems. Inform your doctor if you have a severe problem with lactose (milk sugar) or other sugars as Tasigna 150Mg Capsule may contain lactose. Most people who have mild or moderate lactose intolerance can take Tasigna 150Mg Capsule. Avoid taking Tasigna 150Mg Capsule if you have low levels of magnesium or potassium in the blood or long QTc syndrome. If you have had a surgical procedure involving the removal of the entire stomach (total gastrectomy), inform your doctor before taking Tasigna 150Mg Capsule.

Drug-Drug Interaction: Tasigna 150Mg Capsule may interact with anti-arrhythmic drugs (disopyramide, quinidine, amiodarone, sotalol, procainamide), antibiotics (clarithromycin, moxifloxacin), antimalarial drugs (chloroquine), antipsychotics (haloperidol, pimozide), opioid analgesics (methadone, fentanyl, alfentanil), anticonvulsants (phenytoin, carbamazepine, phenobarbital), blood thinner (warfarin), anti-HIV drug (rifampicin), antifungals (itraconazole, ketoconazole, voriconazole) and immunosuppressants (cyclosporine, tacrolimus, sirolimus). Inform your doctor if you are using any medicines before taking Tasigna 150Mg Capsule.

Drug-Food Interaction: Avoid grapefruit juice, grapefruit and any supplement containing grapefruit extract while taking Tasigna 150Mg Capsule as it may increase the amount of Nilotinib in the body and cause serious side effects. Also, Tasigna 150Mg Capsule may interact with St. John’s wort (a herbal product used to treat depression). 

Drug-Disease Interaction: Avoid taking Tasigna 150Mg Capsule if you have low levels of magnesium or potassium in the blood or long QTc syndrome. If you have had pancreatitis, stroke or other problems due to decreased blood flow to the brain, have QTc prolongation or a family history of it, bleeding problems, irregular heartbeat, have low problems with decreased blood flow to your legs, have low levels of magnesium or potassium in blood, heart or liver problems, inform your doctor before taking Tasigna 150Mg Capsule.

• Drink nutrient-rich liquids such as juices, shakes and soups if you have trouble swallowing solid food.
• Eat frequently by opting for 4 to 6 smaller meals a day instead of 2 to 3 big meals.
• Consume a variety of vegetables, including legumes.
• Eat whole grains, whole fruits, and fat-free or low-fat dairy products.
• Include a variety of proteins in the diet, such as lean meats, poultry, seafood, soy, beans, and eggs.
• Use healthy oils such as olive oil.
• Drink plenty of water to keep yourself hydrated.

• Tasigna 150Mg Capsule can cause a possibly life-threatening heart problem called QTc prolongation (causes irregular heartbeat, which may lead to sudden death). Therefore, if you faint, feel lightheaded or have an irregular heartbeat while taking Tasigna 150Mg Capsule, please contact your doctor immediately, as these might be symptoms of QTc prolongation.

Regular tests are recommended during treatment with Tasigna 150Mg Capsule:

• To monitor the number of blood cells (red blood cells, white blood cells and platelets), liver and pancreas function in the body to see how Tasigna 150Mg Capsule is tolerated.
• To monitor electrolytes (magnesium, potassium) in the body that are essential in the functioning of the heart.
• To check the level of fats and sugar in the blood.
• Also, ECG is recommended to check the heart rate.