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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tazowin 1ml Injection is used to relieve moderate to severe pain. It is indicated in the management of pain severe enough to require an opioid analgesic, for which alternative treatment is inadequate. It is also used as a pre-anaesthetic or pre-operative medication and as a supplement to surgical anaesthesia. It contains Pentazocine, which changes how the nervous system and brain respond to pain. Thereby, it helps provide relief from pain.

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Whats That

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Composition :

PENTAZOCINE-30MG

Manufacturer/Marketer :

Themis Pharmaceutical Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Tazowin 1ml Injection

Tazowin 1ml Injection belongs to a group of medicines called opiates/narcotic analgesics used to relieve moderate to severe pain. It is indicated in the management of pain severe enough to require an opioid analgesic for which alternative treatment is inadequate. It is also used as a pre-anaesthetic or pre-operative medication and as a supplement to surgical anaesthesia.

Tazowin 1ml Injection contains ‘Pentazocine’, which works by changing the way the nervous system and brain respond to pain. Thereby, Tazowin 1ml Injection helps provide relief from pain.

In some cases, Tazowin 1ml Injection may cause common side effects such as nausea, vomiting, dizziness or lightheadedness and euphoria. You are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating machinery as Tazowin 1ml Injection may impair the physical and mental ability. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Tazowin 1ml Injection

Treatment of Pain

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Tazowin 1ml Injection belongs to a group of medicines called opiates/narcotic analgesics used to relieve moderate to severe pain. It is indicated in the management of pain severe enough to require an opioid analgesic for which alternative treatment is inadequate. It is also used as a pre-anaesthetic or pre-operative medication and as a supplement to surgical anaesthesia. Tazowin 1ml Injection contains ‘Pentazocine’, which works by changing the way the nervous system and brain respond to pain. Thereby, Tazowin 1ml Injection helps provide relief from pain.

How Tazowin 1ml Injection Works

Tazowin 1ml Injection contains ‘Pentazocine’, which works by changing the way the nervous system and brain respond to pain. Thereby, Tazowin 1ml Injection helps provide relief from pain.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tazowin 1ml Injection
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • If taking a prescription drug causes euphoria as a side effect. Discuss with your physician. Medication changes or dosage adjustments can be required.
  • Activities that benefit stabilize mood include breathing techniques, meditation, and moderate yoga.
  • Normal sleep habits, as rest is necessary for emotional balance.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Tazowin 1ml Injection

As Tazowin 1ml Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Tazowin 1ml Injection may cause anxiety, dizziness or drowsiness, nightmares, hallucinations, fast heartbeats, tingling sensation, seizures (convulsions), unusual thoughts and very slow breathing.

Drug Warnings

Do not take Tazowin 1ml Injection if you are allergic to any of its components; if you have significant respiratory depression, acute or severe bronchial asthma in the absence of resuscitative equipment or in an unmonitored setting, gastrointestinal obstruction, including paralytic ileus. Inform your doctor if you have/had liver or kidney problems, adrenal insufficiency, severe hypotension, seizures, myocardial infarction, or biliary surgery. Consult your doctor if you are pregnant or breastfeeding. Concomitant use of opioids with benzodiazepines, and other central nervous system agents, including alcohol, might result in profound sedation, respiratory depression, coma, and death. Tazowin 1ml Injection may cause serious respiratory depression; hence monitoring is advised.

Drug-Drug Interactions

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PentazocineAlvimopan
Severe

Drug-Drug Interactions

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How does the drug interact with Tazowin 1ml Injection:
Taking Naltrexone with Tazowin 1ml Injection can reduce the effects of Tazowin 1ml Injection and make the medication less effective.

How to manage the interaction:
Taking Tazowin 1ml Injection with Naltrexone is generally avoided, but can be taken together if prescribed by a doctor. However, if you experience any symptoms like nausea, vomiting, diarrhoea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
PentazocineAlvimopan
Severe
How does the drug interact with Tazowin 1ml Injection:
Using Tazowin 1ml Injection with Alvimopan can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Tazowin 1ml Injection and Alvimopan together can evidently cause an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience abdominal pain, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tazowin 1ml Injection:
Taking Bupropion with Tazowin 1ml Injection may increase the risk of side effects including respiratory distress(breathing problems), unconsciousness.

How to manage the interaction:
Taking Tazowin 1ml Injection and Buspirone together, can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tazowin 1ml Injection:
Taking Nalbuphine with Tazowin 1ml Injection can increase the risk of serious side effects.

How to manage the interaction:
Although taking Tazowin 1ml Injection and Nalbuphine together can evidently cause an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Tazowin 1ml Injection:
When buprenorphine is used with Tazowin 1ml Injection, it may lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of buprenorphine alongside Tazowin 1ml Injection can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tazowin 1ml Injection:
Taking Tazowin 1ml Injection with Citalopram can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Co-administration of Tazowin 1ml Injection with Citalopram can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
PentazocinePentobarbital
Severe
How does the drug interact with Tazowin 1ml Injection:
Taking Pentobarbital with Tazowin 1ml Injection can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Tazowin 1ml Injection and Pentobarbital, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tazowin 1ml Injection:
Using Lurasidone together with Tazowin 1ml Injection can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Even though Tazowin 1ml Injection and Lurasidone interact, they can be taken if prescribed by a doctor. Consult a doctor if you develop dizziness, drowsiness, difficulty concentrating, or problems in judgment, reaction speed, or movement control. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tazowin 1ml Injection:
Using Codeine and Tazowin 1ml Injection may increase the risk of breathing problems.

How to manage the interaction:
Although taking Tazowin 1ml Injection and Codeine together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PentazocineMeprobamate
Severe
How does the drug interact with Tazowin 1ml Injection:
Taking Meprobamate with Tazowin 1ml Injection can increase the risk of serious side effects.

How to manage the interaction:
Co-administration of Tazowin 1ml Injection with Meprobamate can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include fresh fruits and vegetables in your diet.
  • Rest and sleep well.
  • Stay hydrated, and drink plenty of water.
  • Eat anti-inflammatory foods.

Habit Forming

Yes

Therapeutic Class

NARCOTIC (OPIOID) ANALGESIC
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Alcohol

Unsafe

Avoid the consumption of alcohol, as it may cause profound sedation.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Tazowin 1ml Injection. Prolonged use of Tazowin 1ml Injection in pregnancy may cause neonatal opioid withdrawal syndrome.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Tazowin 1ml Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks. Infants exposed to Tazowin 1ml Injection through breast milk should be monitored for excessive sedation and respiratory depression. Withdrawal symptoms can develop in breastfed babies when maternal administration of an opioid painkiller is stopped or when nursing is terminated.

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Driving

Unsafe

Tazowin 1ml Injection may alter your physical and mental ability. Therefore, avoid driving or operating machinery.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Tazowin 1ml Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Tazowin 1ml Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Caution

Tazowin 1ml Injection is not recommended for use in children under one year. The doctor will decide the dose of this medicine based on the age, body weight and clinical condition of your child.

Have a query?

FAQs

Tazowin 1ml Injection is used to treat Pain.

Tazowin 1ml Injection works by changing the way the nervous system and brain respond to pain.

Tazowin 1ml Injection may cause respiratory depression. Monitoring for respiratory depression during the initiation of treatment or following a dose increase is advised.

It is contraindicated for use in patients with known or suspected gastrointestinal obstruction, including paralytic ileus. Consult your doctor if you have any concerns.

While on therapy with Tazowin 1ml Injection, be cautious if you have experience drowsiness and dizziness, or if you have breathing problems, and avoid driving or operating heavy machinery. Inform your doctor, if you have respiratory depression, asthma, gastrointestinal obstruction, liver or kidney issues, low blood pressure, seizures, heart problems, or a history of biliary surgery. Consult your doctor if pregnant or breastfeeding. Be aware of the potential for dependence or withdrawal symptoms with prolonged use of Tazowin 1ml Injection with opioids, benzodiazepines, alcohol, or other CNS depressants, as they can cause severe sedation and breathing problems. Therefore, monitoring is recommended due to the risk of respiratory depression.

Tazowin 1ml Injection causes side effects such as nausea, vomiting, dizziness or lightheadness, and euphoria (a feeling of intense happiness or excitement). However, please contact a doctor if these side effects persist for longer durations.

Country of origin

INDIA

Manufacturer/Marketer address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Other Info - TAZ0148

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