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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Terlicure Injection is used to treat Bleeding oesophageal varices. It contains Terlipressin, a synthetic pituitary hormone that breaks down in the body to release a substance called lysine vasopressin that is used to stop bleeding from leaking varicose veins in the food pipe. It works by narrowing the affected blood vessels and restricting their flow. Thus, it helps to control bleeding.

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Whats That

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Composition :

TERLIPRESSIN-1MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Terlicure Injection

Terlicure Injection belongs to the class of drugs called vasopressin receptor agonists used for the treatment of bleeding oesophageal varices and the emergency treatment of type 1 hepatorenal syndrome (rapidly progressive kidney failure) in patients with ascites (abdominal swelling due to accumulation of fluid) and liver cirrhosis (scarring of the liver). Bleeding oesophageal varices occur when there is bleeding from dilated veins in the food pipe leading to your stomach.

Terlicure Injection contains Terlipressin, a synthetic pituitary hormone that breaks down in the body to release a substance called lysine vasopressin that is used to stop bleeding from leaking varicose veins in the food pipe. It works by narrowing the affected blood vessels and restricting the blood flow through them. Thus, it helps to control bleeding.

Terlicure Injection will be administered by a healthcare professional; do not self-administer. Sometimes, Terlicure Injection may cause common side effects such as headache, diarrhoea, abdominal cramps, high or low blood pressure, too slow heart rate, pale skin, and insufficient blood circulation in arms, legs and skin. Most of these side effects of Terlicure Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Terlipressin or other medicines, please tell your doctor. Terlicure Injection is not recommended for children and adolescents as the safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, please inform your doctor before receiving Terlicure Injection. If you are elderly above 70 years of age, discuss with your doctor before receiving Terlicure Injection.

Uses of Terlicure Injection

Treatment of Bleeding oesophageal varices

Directions for Use

Terlicure Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Terlicure Injection contains Terlipressin used for the treatment of bleeding oesophageal varices. It narrows the affected blood vessels and restricts the blood flow through them. Thus, it helps to control bleeding. Also, it is used for the emergency treatment of type 1 hepatorenal syndrome (rapidly progressive kidney failure) in patients with ascites (abdominal swelling due to accumulation of fluid) and liver cirrhosis (scarring of the liver).

How Terlicure Injection Works

Terlicure Injection contains Terlipressin, a synthetic pituitary hormone that breaks down in the body to release a substance called lysine vasopressin that is used to stop bleeding from leaking varicose veins in the food pipe. It works by narrowing the affected blood vessels and restricting the blood flow through them. Thus, it helps to control bleeding.

Storage

Store in a cool and dry place away from sunlight
Side effects of Terlicure Injection
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Consult a doctor when you have signs such as pain, numbness, or discoloration in order to establish the cause and get the proper treatment.
  • Medications may be prescribed by your doctor to promote blood flow and prevent further complications.
  • Exercise often, such as walking or swimming, to increase cardiovascular health and circulation.
  • Keep yourself at an ideal weight because excess weight creates strain on the blood vessels, and improves the circulation.
  • Stop smoking since it damages the blood vessels and impairs circulation.
  • Relieve stress through techniques such as meditation or deep breathing.
  • Avoid very cold temperatures as they can constrict blood vessels and reduce the flow of circulation.
  • Drink sufficient water to allow good blood circulation.
  • Monitor blood pressure regularly and ensure that it is within the healthy range.

What if I have taken an overdose of Terlicure Injection

Since Terlicure Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

If you are allergic to Terlipressin or any other medicines, please tell your doctor. Terlicure Injection is not recommended for children and adolescents as the safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, please inform your doctor before receiving Terlicure Injection. If you are elderly above 70 years of age, discuss with your doctor before receiving Terlicure Injection. If you experience dizziness, lightheadedness, or feeling faint, inform your doctor, as these could be signs of a low heart rate. Your heart and blood circulation will be monitored continuously while on treatment with Terlicure Injection.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Eat a balanced diet consisting of whole grains, lean protein, low salt, fruits, and vegetables.
  • Maintain a healthy weight.
  • Avoid alcohol consumption.
  • Lower your risk for hepatitis (inflammation of the liver) by practising safer sex. Avoid sharing razors or needles, and avoid contact with the blood and other bodily fluids of a person who has hepatitis.

Habit Forming

No

Therapeutic Class

VASOACTIVE DRUG
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Alcohol

Consult your doctor

The interaction of Terlicure Injection with alcohol is unknown. Therefore, if you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

Limited data available on the effect of Terlicure Injection on pregnant women. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Terlicure Injection. Your doctor may give this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Terlipressin is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before receiving Terlicure Injection. Your doctor may give this medicine if the benefits outweigh the risks.

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Driving

Caution

Limited information is available. However, if you are unwell after receiving Terlicure Injection, avoid driving or operating machinery.

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Liver

Consult your doctor

If you have any liver problems, inform your doctor before receiving Terlicure Injection.

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Kidney

Caution

Terlicure Injection should be used with caution in patients with long-standing kidney failure. Also, inform your doctor if you have impaired kidney function.

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Children

Unsafe

Terlicure Injection is not recommended for children and adolescents as the safety and effectiveness were not established.

Have a query?

FAQs

Terlicure Injection is used to treat Bleeding oesophageal varices.

Terlicure Injection contains Terlipressin, a synthetic pituitary hormone that works by narrowing the affected blood vessels and restricting the blood flow through them. Thus, it helps to control bleeding.

You are recommended to consult a doctor before taking quinidine while on treatment with Terlicure Injection as it may increase the risk or severity of QT prolongation (a heart rhythm disorder). Therefore, please consult a doctor before taking other medicines with Terlicure Injection.

Terlicure Injection may cause headaches as a common side effect. However, if the condition persists or worsens, please inform your doctor.

The side effects of Terlicure Injection include abdominal cramps, diarrhoea, high or low blood pressure, slow heart rate, headache, pale skin, and insufficient blood circulation in arms, legs and skin. Consult the doctor if any of these symptoms persist or worsen.

Terlicure Injection should not be taken if you are allergic to any of its ingredients, experiencing hypoxia (low levels of oxygen) or worsening respiratory symptoms, or have ongoing coronary, peripheral, or mesenteric ischemia (conditions affecting blood flow).

Before taking Terlicure Injection, let your doctor know if you have severe bleeding in the oesophagus (food pipe). If you have a severe infection like septic shock, breathing issues such as asthma, uncontrolled high blood pressure, heart problems (angina, arrhythmias, or a history of heart attack), poor blood circulation (to the brain or limbs), kidney impairment, electrolyte imbalances, significant fluid or blood loss, if you are pregnant, or are over 70 years old.

Terlicure Injection will be given as a continuous intravenous infusion by the doctor or nurse. Do not self-administer.

Terlicure Injection is not recommended for children as its safety and effectiveness were not established.

Country of origin

India
Other Info - TE19481

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