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compositionComposition:LIDOCAINE-2% W/V
prescriptionPrescription Medicine
Themicaine Inj - 2% / 30Ml

Themicaine Inj - 2% / is used as a local anaesthesia during surgery or medical procedures. This medicine is also used in the management of ventricular arrhythmia (abnormal heartbeat). It prevents the beginning and conduction of impulses by obstructing the influx (entry) of sodium ions into the membrane surrounding the nerves. Common side effects include dizziness, high/low blood pressure, nausea, vomiting, and paresthesia (burning or prickling sensation).

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

LIDOCAINE-2% W/V

Manufacturer/Marketer :

Themis Pharmaceutical Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Themicaine Inj - 2% /

Themicaine Inj - 2% / is indicated for the production of regional or local anaesthesia during surgery or medical procedures. Additionally, it is indicated in the management of ventricular arrhythmia (abnormal heartbeat) associated with acute myocardial infarction or cardiac surgery.

Themicaine Inj - 2% / contains Lidocaine, which works by preventing initiation and conduction of impulses; hence providing an anaesthetic effect. Themicaine Inj - 2% / blocks cardiac sodium channels, thereby treating arrhythmia.

In some cases, you may experience side effects such as dizziness, high/low blood pressure, nausea, vomiting, and paresthesia (burning or prickling sensation). You are advised to talk to your doctor if you experience these side effects persistently.

Do not take Themicaine Inj - 2% / if you are allergic to any of its components. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Themicaine Inj - 2% /

Themicaine Inj - 2% / is used to provide local anaesthesia and manage certain heart conditions. The detailed uses of Themicaine Inj - 2% / include:

  • Local anaesthesia: Themicaine Inj - 2% / is applied to numb specific areas of the body during minor surgical procedures, dental work, or diagnostic tests.
  • Treatment of ventricular arrhythmia: Themicaine Inj - 2% / is used to treat irregular heart rhythms originating from the lower chambers of the heart, particularly during cardiac emergencies.

Have a query?

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Themicaine Inj - 2% / will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Key Benefits

  • Themicaine Inj - 2% / is used to produce local or regional anaesthesia during surgeries or medical procedures.
  • It provides numbness and pain relief by blocking nerve signals in a specific area of the body.
  • It helps in the management of ventricular arrhythmias (abnormal heart rhythms), especially after a heart attack or cardiac surgery.
  • It blocks the entry of sodium ions into nerve membranes, preventing pain signal transmission and ensuring effective anaesthesia.
  • It stabilises cardiac electrical activity by blocking sodium channels in the heart, helping restore a normal heart rhythm.
  • Themicaine Inj - 2% / offers dual therapeutic benefits, as a local anaesthetic and as an antiarrhythmic agent.
  • It ensures safe and effective control of pain and cardiac rhythm disturbances during medical and surgical care.

How Themicaine Inj - 2% / Works

Themicaine Inj - 2% / contains Lidocaine that blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses; hence providing an anaesthetic effect. Themicaine Inj - 2% / blocks cardiac sodium channels, thereby treating arrhythmia.

What if I have taken an overdose of Themicaine Inj - 2% /

Themicaine Inj - 2% / is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include CNS depression, including unconsciousness and coma. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

  • Do not take Themicaine Inj - 2% / if you are allergic to any of its components.
  • Inform your doctor if you have hypovolemia (low blood volume), blood clotting problems, bleeding problems, slow heart rate, myasthenia gravis (muscle problems), epilepsy, heart, kidney or liver problems.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Avoid driving or operating machinery as Themicaine Inj - 2% / may cause dizziness, drowsiness and loss of sensation.
  • Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Drug-Drug Interactions

verifiedApollotooltip
LidocaineSaquinavir
Critical
LidocaineArbutamine
Critical

Drug-Drug Interactions

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LidocaineSaquinavir
Critical
How does the drug interact with Themicaine Inj - 2% / 30Ml:
Taking Themicaine Inj - 2% / 30Ml with Saquinavir can increase the blood levels of Themicaine Inj - 2% / 30Ml and cause an irregular heart rhythm.

How to manage the interaction:
Taking Themicaine Inj - 2% / 30Ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
LidocaineArbutamine
Critical
How does the drug interact with Themicaine Inj - 2% / 30Ml:
Taking Themicaine Inj - 2% / 30Ml and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Themicaine Inj - 2% / 30Ml with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineNitric oxide
Severe
How does the drug interact with Themicaine Inj - 2% / 30Ml:
Taking Themicaine Inj - 2% / 30Ml with Nitric Oxide can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Themicaine Inj - 2% / 30Ml with Nitric oxide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineIsosorbide dinitrate
Severe
How does the drug interact with Themicaine Inj - 2% / 30Ml:
Taking isosorbide dinitrate with Themicaine Inj - 2% / 30Ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide dinitrate and Themicaine Inj - 2% / 30Ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineAmyl nitrite
Severe
How does the drug interact with Themicaine Inj - 2% / 30Ml:
Taking Themicaine Inj - 2% / 30Ml with Amyl nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Themicaine Inj - 2% / 30Ml and Amyl nitrite, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineRasburicase
Severe
How does the drug interact with Themicaine Inj - 2% / 30Ml:
Taking Rasburicase with Themicaine Inj - 2% / 30Ml can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasburicase with Themicaine Inj - 2% / 30Ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineDofetilide
Severe
How does the drug interact with Themicaine Inj - 2% / 30Ml:
Taking Themicaine Inj - 2% / 30Ml together with Dofetilide can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
There may be a possibility of interaction between Themicaine Inj - 2% / 30Ml and Dofetilide, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without first consulting your doctor.
LidocaineSulfadiazine
Severe
How does the drug interact with Themicaine Inj - 2% / 30Ml:
Taking Themicaine Inj - 2% / 30Ml with Sulfadiazine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Themicaine Inj - 2% / 30Ml with Sulfadiazine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocainePrimaquine
Severe
How does the drug interact with Themicaine Inj - 2% / 30Ml:
Taking primaquine with Themicaine Inj - 2% / 30Ml may increase the risk of methemoglobinemia(blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although taking Primaquine and Themicaine Inj - 2% / 30Ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience grayish discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, weakness, lightheadedness, rapid or shallow breathing, a rapid heartbeat, anxiety, or confusion contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
LidocaineChloroquine
Severe
How does the drug interact with Themicaine Inj - 2% / 30Ml:
Combination of chloroquine and Themicaine Inj - 2% / 30Ml can increase the risk of methemoglobinemia (an uncommon disease that can result in low oxygen levels in tissues and important organs).

How to manage the interaction:
Taking chloroquine and Themicaine Inj - 2% / 30Ml together can possibly result in an interaction, it can be taken if your doctor has advised it. If you experience any of the following symptoms: gray discoloration of the skin, abnormal blood coloring, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, rapid heartbeat, palpitations, anxiety, or confusion, consult your doctor

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include a diet rich in whole grains, lean proteins, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with a proper diet and safe exercises.
  • Manage stress with meditation and yoga.

Habit Forming

No

Therapeutic Class

[VASOPRESSORS]

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Alcohol

Caution

It is not known if alcohol affects Themicaine Inj - 2% /. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Your doctor will decide if Themicaine Inj - 2% / can be taken by breastfeeding mothers or not.

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Driving

Caution

Avoid driving or operating machinery as Themicaine Inj - 2% / may cause dizziness, drowsiness and loss of sensation.

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Liver

Caution

Themicaine Inj - 2% / should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Themicaine Inj - 2% / should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have any concerns regarding this.

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Children

Caution

Limited information is available. Please consult your doctor if you have any concerns regarding the usage of Themicaine Inj - 2% / in children.

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Heart

Caution

Themicaine Inj - 2% / should be used with caution in patients with heart disease. Please consult your doctor if you have any concerns regarding this.

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Geriatrics

Caution

Themicaine Inj - 2% / should be used with caution in elderly patients. Please consult your doctor before use.

FAQs

Themicaine Inj - 2% / is indicated for the production of regional or local anaesthesia during surgery or medical procedures. Additionally, it is indicated in the management of ventricular arrhythmia (abnormal heartbeat) associated with acute myocardial infarction or cardiac surgery.

Themicaine Inj - 2% / blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses and hence providing an anaesthetic effect. Themicaine Inj - 2% / blocks cardiac sodium channels, thereby treating arrhythmia.

Themicaine Inj - 2% / may cause hypotension (low blood pressure) or hypertension (high blood pressure). Therefore, regular monitoring of blood pressure is advised whilst on treatment with Themicaine Inj - 2% /.

Nausea and vomiting might be side effects of Themicaine Inj - 2% /. It is not necessary for everyone taking Themicaine Inj - 2% / to experience these side effects. However, if the condition persists or worsens, please consult a doctor.

Themicaine Inj - 2% / might increase creatinine phosphokinase levels. Therefore, if you are undergoing any tests, inform the person doing the tests that you have taken Themicaine Inj - 2% /.

Country of origin

INDIA

Manufacturer/Marketer address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Other Info - THE0226

Disclaimer

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Author Details

Santoshini Reddy GDoctor badge

Written By

  • Santoshini Reddy G

    M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

  • Veda Maddala

    M Pharmacy

Last Updated

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