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THYMOGAM INJECTION

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

THYMOGAM INJECTION is used to prevent and treat acute rejection in patients receiving a kidney transplant. It may also treat aplastic anaemia in patients unsuitable for bone marrow transplantation. It contains Antithymocyte immunoglobulin, which lowers specific cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

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Composition :

ANTITHYMOCYTE IMMUNOGLOBULIN-250MG

Manufacturer/Marketer :

Bharat Biotech

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About THYMOGAM INJECTION

THYMOGAM INJECTION belongs to the group of medicines called immunosuppressants indicated for the prevention and treatment of acute rejection in patients receiving a kidney transplant. It may also be used to treat aplastic anaemia in patients unsuitable for bone marrow transplantation.

THYMOGAM INJECTION contains antithymocyte immunoglobulin, which works by preventing the white blood cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

In some cases, THYMOGAM INJECTION may cause side effects such as fever, chills, low white blood cell count, low platelet count, blood clotting problems, and skin rash. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in THYMOGAM INJECTION. Consult the doctor THYMOGAM INJECTION if you are pregnant. Avoid breastfeeding during treatment. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of THYMOGAM INJECTION

Prevention and treatment of Kidney transplant rejection and aplastic anaemia

Directions for Use

THYMOGAM INJECTION will be administered by a healthcare professional; do not self-administer. It should only be used by physicians experienced in immunosuppressive therapy to treat kidney transplant patients.

Medicinal Benefits

THYMOGAM INJECTION belongs to the group of medicines called immunosuppressants indicated for preventing and treating acute rejection in patients receiving a kidney transplant. It may also be used to treat aplastic anaemia in patients unsuitable for bone marrow transplantation. THYMOGAM INJECTION contains Antithymocyte immunoglobulin, which lowers certain cells within the immune system that are likely to attack the transplanted kidney. It helps to stop the body's immune system from rejecting the new kidney.

How THYMOGAM INJECTION Works

Storage

Store in a cool and dry place away from sunlight

Side effects of Thymogam Injection

Urinary Tract Infection

Managing Medication-Triggered UTIs: A Comprehensive Approach:

Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
Monitor UTI symptoms and report any changes to your doctor.
If antibiotics are prescribed, take them as directed and complete the full course.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Difficulty Breathing

Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):

Tell your doctor immediately if you experience shortness of breath after taking medication.
Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

High Body Temperature

Here's a comprehensive approach to managing medication-triggered fever:

Inform your doctor immediately if you experience a fever after starting a new medication.
Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
Monitor your body temperature to monitor fever progression.
Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Anxiety

Managing Medication-Triggered Anxiety: A Comprehensive Approach:

Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.

What if I have taken an overdose of THYMOGAM INJECTION

As THYMOGAM INJECTION is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not use THYMOGAM INJECTION if you are allergic to any of its components. Inform the doctor if you have any active infection. Consult the doctor if you are pregnant or think you may be pregnant. Avoid/discontinue breastfeeding during treatment with THYMOGAM INJECTION. Seek medical attention if you experience symptoms of cytokine release syndrome (fever, chills, headache, chest pain, low blood pressure, shortness of breath, fast breathing, and swelling), infusion-associated reactions (generalised rash, fast heart rate, shortness of breath, and low blood pressure), or serum sickness (rash, joint pain, fever, chills, and pain). Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

Antithymocyte GlobulinBaricitinib

Severe

Antithymocyte GlobulinEtanercept

Severe

Drug-Drug Interactions

Antithymocyte GlobulinBaricitinib

Severe

How does the drug interact with Thymogam Injection:
Taking Antithymocyte Globulin with Baricitinib can increase the risk of developing serious infections as well as some cancers over time.

How to manage the interaction:
Taking Antithymocyte Globulin with Baricitinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Antithymocyte GlobulinEtanercept

Severe

How does the drug interact with Thymogam Injection:
When Etanercept is used with Antithymocyte Globulin, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Antithymocyte Globulin and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Antithymocyte GlobulinTofacitinib

Severe

How does the drug interact with Thymogam Injection:
Using tofacitinib together with antithymocyte globulin can increase the risk of serious infections.

How to manage the interaction:
Taking Antithymocyte Globulin with Tofacitinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact your doctor. Do not discontinue any medications without consulting your doctor.

Antithymocyte GlobulinClozapine

Severe

How does the drug interact with Thymogam Injection:
Co-administration of Antithymocyte Globulin and Clozapine may increase the effect of neutropenia.

How to manage the interaction:
Although taking Antithymocyte Globulin and Clozapine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any signs of infection like fever, chills, or sore throat, or if you have any other symptoms like diarrhea or muscle aches, make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Eat a healthy diet and exercise regularly to maintain proper weight.
Avoid smoking and alcohol consumption.
Avoid fast food, fried food, processed meats, refined carbs and added sugar.
Get optimal sleep; rest well.

Habit Forming

Therapeutic Class

IMMUNOSUPPRESSANTS

THYMOGAM INJECTION Substitute

Atgam 250 Injection 5 ml

by Others

₹2882.88per tablet

Product Substitutes

Atgam 250 Injection 5 ml

₹14414.4

MRP ₹16380

Alcohol

Consult your doctor

It is not known if alcohol affects THYMOGAM INJECTION. Please consult your doctor.

Pregnancy

Caution

Consult the doctor if you are pregnant, think you may be pregnant or are planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with THYMOGAM INJECTION. Seek medical advice before taking this medicine if you want to breastfeed your child.

Driving

Caution

Do not drive or operate heavy machinery after the treatment with THYMOGAM INJECTION as it may cause side effects. ask your doctor for more information.

Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving THYMOGAM INJECTION.

Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving THYMOGAM INJECTION.

Children

Consult your doctor

Information about the use of THYMOGAM INJECTION in children is limited. Consult the doctor if you have any concerns.

Have a query?

FAQs

What is the use of THYMOGAM INJECTION?

THYMOGAM INJECTION is used to prevent and treat acute rejection in patients receiving a kidney transplant. It may also treat aplastic anaemia in patients unsuitable for bone marrow transplantation.

How does THYMOGAM INJECTION help?

THYMOGAM INJECTION helps to stop your body's immune system from rejecting the new kidney.

Does THYMOGAM INJECTION cause infections?

Due to immunosuppressive effects, infections have been reported during treatment with THYMOGAM INJECTION. Careful patient monitoring and appropriate anti-infective prophylaxis are recommended. Consult the doctor immediately if you notice signs of infections such as fever, chills, pale skin, shortness of breath, tiredness, or mouth sores.

Can I undergo immunisation while on treatment with THYMOGAM INJECTION?

Concomitant use of THYMOGAM INJECTION with live vaccines is not advised, as live vaccines may interfere with THYMOGAM INJECTION treatment. Talk to the doctor if you are undergoing any vaccination.

Country of origin

India

Manufacturer/Marketer address

Genome Valley Shameerpet, Hyderabad – 500 078 Telagana INDIA

Other Info - THY0018

Disclaimer

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 9:31 AM IST

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Composition :

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Consume Type :

Return Policy :

Expires on or after :

Drug-Drug Interactions

Drug-Food Interactions

THYMOGAM INJECTION Substitute

Atgam 250 Injection 5 ml

Atgam 250 Injection 5 ml

FAQs

What is the use of THYMOGAM INJECTION?

How does THYMOGAM INJECTION help?

Does THYMOGAM INJECTION cause infections?

Can I undergo immunisation while on treatment with THYMOGAM INJECTION?

Disclaimer

Author Details

Reference