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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tiobend 400mg Tablet is an anti-parasite medicine used to treat different parasitic infections in children. It contains Albendazole as an active ingredient belonging to the class of benzimidazole drugs. It works by inhibiting tubulin polymerisation, causing metabolic disruption and energy depletion in the parasite, leading to immobilization. This eventually leads to the death of susceptible helminths and thus prevents the growth of parasitic infections.

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Composition :

ALBENDAZOLE-400MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Tiobend 400mg Tablet

Tiobend 400mg Tablet is an anti-parasite medicine used to treat different parasitic infections in children. Parasitic infections are diseases caused by parasites (micro-organisms) that live in or on another host/organism. Tiobend 400mg Tablet is used in treating infections of the roundworms, hookworms, threadworms, whipworms, pinworms, and flukes caused by parasites. It is also used to treat neurocysticercosis (infection caused by pork tapeworm) and cystic hydatid disease (infection caused by dog tapeworm).

Tiobend 400mg Tablet contains Albendazole as an active ingredient belonging to the class of benzimidazole drugs. It works by inhibiting tubulin polymerisation, causing metabolic disruption and energy depletion in the parasite, leading to immobilization. This eventually leads to the death of susceptible helminths and thus prevents the growth of parasitic infections. 

Tiobend 400mg Tablet may cause certain side effects in your child, such as indigestion, diarrhea, nausea, metallic taste, vomiting, headache, and stomach pain. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your pediatrician. Tiobend 400mg Tablet should be given as advised by your doctor. Do not give the child more than the prescribed dose of Tiobend 400mg Tablet. Generally, the dose of the medicine will be decided by your pediatrician depending upon the type and severity of the infection.

Tiobend 400mg Tablet is intended for pediatric use only. Avoid giving Tiobend 400mg Tablet to your child if she/he is allergic to antibiotics. Keep your doctor informed about your child’s health condition, medications, and medical history to rule out any side effects/interactions. Avoid giving Tiobend 400mg Tablet if you notice any unusual bleeding or bruising symptoms in your child, and consult your paediatrician immediately.

Uses of Tiobend 400mg Tablet

Tiobend 400mg Tablet is used in treatment of Parasitic Infections. The detailed uses of Tiobend 400mg Tablet are as follows:
•Treating Intestinal Worm Infections: Tiobend 400mg Tablet is commonly prescribed to combat various intestinal worm infections, such as those caused by roundworms and hookworms.
•Managing Neurocysticercosis: Tiobend 400mg Tablet effectively treats neurocysticercosis, a central nervous system condition resulting from the larval stage of the pork tapeworm (Taenia solium).
•Treatment of Echinococcosis: Tiobend 400mg Tablet is also used to address echinococcosis, an infection caused by Echinococcus granulosus, which leads to cyst formation in organs like the liver or lungs.
•Alternative Management of Giardiasis: Though not the primary treatment, Tiobend 400mg Tablet can be an alternative for managing giardiasis, an intestinal infection caused by the Giardia lamblia parasite.

Directions for Use

Shake the container well before each use. Measure the required amount of Tiobend 400mg Tablet into the measuring cup and administer it to your child. It is advised to measure the quantity accurately with the help of a syringe or measuring spoon/cup containing markings.

Medicinal Benefits

Tiobend 400mg Tablet contains Albendazole. It is a broad-spectrum anthelmintic that acts against intestinal nematode and cestode infection. Tiobend 400mg Tablet is used in the treatment of several parasitic infections in children. It works by inhibiting tubulin polymerisation, causing metabolic disruption and energy depletion in the parasite, leading to immobilization. This eventually leads to the death of susceptible helminths and thus prevents the growth of parasitic infections.  

How Tiobend 400mg Tablet Works

Tiobend 400mg Tablet contains Albendazole as an active ingredient belonging to the class of benzimidazole drugs. It works by inhibiting tubulin polymerisation, causing metabolic disruption and energy depletion in the parasite, leading to immobilization. This eventually leads to the death of susceptible helminths and thus prevents the growth of parasitic infections.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tiobend 400mg Tablet
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Your doctor can provide you with some medications to reduce the production of cerebrospinal fluid and subsequently lower intracranial pressure.
  • Tell your doctor immediately when you feel more severe symptoms like changes in vision, confusion, or even seizure.
  • Take fruits, vegetables, lean proteins, and whole grains to maintain a balanced diet.
  • Reduce your intake of sodium for better fluid retention and lower blood pressure.
  • Keep yourself fit with a healthy weight to decrease intracranial pressure.
  • Yoga, meditation, and deep breathing will help reduce your stress levels.
  • Regularly visiting the doctor helps monitor progress, health of eyes, and intracranial pressure.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use suitable comb to detangle hair gently, especially when wet.
  • Avoid harsh chemicals like strong dyes and relaxers.
  • Limit heat styling tools like curling irons and flat irons.
  • Massaging your scalp regularly helps to stimulate blood circulation.
  • Avoid tight hairstyles like ponytails, braids, or buns that can pull on the hair.
  • Change hairstyles frequently to avoid putting constant tension on the same hair follicles.
  • Ensure adequate intake of iron, zinc, vitamin B12, and biotin, which are crucial for healthy hair growth.
  • Take balanced diet with plenty of fruits, vegetables, and whole grains.
  • Manage stress levels by practicing yoga and meditation.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

What if I have taken an overdose of Tiobend 400mg Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. If you suspect that you may have overdosed of Tiobend 400mg Tablet or observe any side effects, please go to the emergency department of the closest hospital or nursing home. No specific side effects have been reported under these circumstances.

Drug Warnings

Avoid giving Tiobend 400mg Tablet to your child if she/he is allergic to it. Keep your paediatrician informed about your child’s health condition including their previous medications and medical history to rule out any side effects/interactions. Before administration, notify the paediatrician of all the OTC medicines including other vitamin supplements that your child is taking. It is advised not to give more than the prescribed dose of medicine. Also, inform your doctor if your child has liver or kidney-related issues before administration. Tiobend 400mg Tablet is intended for use in children. Hence, pregnant, and breastfeeding mothers should avoid taking this solution.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tiobend 400mg Tablet:
Co-administration of Tiobend 400mg Tablet with Clozapine may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tiobend 400mg Tablet and Clozapine, you can take these medicines together if advised by your doctor. However, if you develop symptoms such as chills, diarrhea, fever, sore throat, shortness of breath, muscle pains, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Tiobend 400mg Tablet:
Taking Tiobend 400mg Tablet with Cladribine can increase the risk of side effects.

How to manage the interaction:
Although taking Cladribine and Tiobend 400mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, contact a doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ALBENDAZOLE-400MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ALBENDAZOLE-400MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit and Grapefruit juice can increase the absorption of Tiobend 400mg Tablet. Avoid consuming Grapefruit and Grapefruit juice while being treated with Tiobend 400mg Tablet.

Diet & Lifestyle Advise

  • Include more fiber-enriched food in your child’s diet, as it can be easily digested by gut bacteria, which helps stimulate their growth.
  • Fiber foods may help restore healthy gut bacteria after a course of antibiotics.
  • Make your child drink more fluids to avoid dehydration.
  • Maintain proper hygiene for your child
  • Make your child drink clean and filtered water.
  • If your child is infected, avoid giving non-vegetarian food for some days.
  • Regularly wash your child's hands with soap and water, especially after using the toilet and while eating.

Habit Forming

No

Therapeutic Class

ANTIHELMINTICS
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

If your child has liver disease, inform your paediatrician before using Tiobend 400mg Tablet.

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Kidney

Caution

If your child has kidney disease, inform your paediatrician before using Tiobend 400mg Tablet.

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Children

Safe if prescribed

Tiobend 400mg Tablet is safe for children above 1 year of age if prescribed by the doctor. Your paediatrician will decide the dose of the medicine. Do not give more than the recommended dose to your child.

Have a query?

FAQs

Tiobend 400mg Tablet is used to treat different parasitic infections in children. It is used in treating infections of the roundworms, hookworms, threadworms, whipworms, pinworms, and flukes caused by parasites. It is also used to treat neurocysticercosis (infection caused by pork tapeworm) and cystic hydatid disease (infection caused by dog tapeworm).

Tiobend 400mg Tablet works by inhibiting tubulin polymerisation, causing metabolic disruption and energy depletion in the parasite, leading to immobilization. This eventually leads to the death of susceptible helminths and thus prevents the growth of parasitic infections.

Tiobend 400mg Tablet can cause diarrhea in children. If your child has diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrheal medicine unless your paediatrician tells you to.

No, it is advised to complete the entire treatment course as prescribed. If the treatment is stopped abruptly, there may be a recurrence of the infection.

Country of origin

India

Manufacturer/Marketer address

711 712, Modi Tower, 98 Nehru Place, New Delhi- 110019, India
Other Info - TI22989

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