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Composition :
TOFACITINIB-11MG
Manufacturer/Marketer :
Cipla Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
TofacitinibStreptozocin
Severe
Drug-Drug Interactions
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How does the drug interact with Tofajak-IN XR 11 mg Tablet:
Hydroxycarbamide when used with Tofajak-IN XR 11 mg Tablet may raise the risk of severe infections, cancers.
How to manage the interaction:
There may be a possibility of interaction between hydroxycarbamide with Tofajak-IN XR 11 mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Hydroxycarbamide when used with Tofajak-IN XR 11 mg Tablet may raise the risk of severe infections, cancers.
How to manage the interaction:
There may be a possibility of interaction between hydroxycarbamide with Tofajak-IN XR 11 mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
TofacitinibStreptozocin
Severe
How does the drug interact with Tofajak-IN XR 11 mg Tablet:
Taking Tofajak-IN XR 11 mg Tablet with Streptozocin may increase the risk of infection.
How to manage the interaction:
Although taking Streptozocin and Tofajak-IN XR 11 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking Tofajak-IN XR 11 mg Tablet with Streptozocin may increase the risk of infection.
How to manage the interaction:
Although taking Streptozocin and Tofajak-IN XR 11 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Tofajak-IN XR 11 mg Tablet:
Co-administration of Deflazacort with Tofajak-IN XR 11 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction between Deflazacort and Tofajak-IN XR 11 mg Tablet, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Deflazacort with Tofajak-IN XR 11 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction between Deflazacort and Tofajak-IN XR 11 mg Tablet, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Tofajak-IN XR 11 mg Tablet:
Taking tacrolimus together with Tofajak-IN XR 11 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although taking tacrolimus and Tofajak-IN XR 11 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
Taking tacrolimus together with Tofajak-IN XR 11 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although taking tacrolimus and Tofajak-IN XR 11 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
Severe
How does the drug interact with Tofajak-IN XR 11 mg Tablet:
Taking Tofajak-IN XR 11 mg Tablet with ritonavir may increase the blood levels of Tofajak-IN XR 11 mg Tablet.
How to manage the interaction:
Although there is a possible interaction between Tofajak-IN XR 11 mg Tablet and Ritonavir, but it can be taken together if prescribed by your doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination Do not stop using any medications without a doctor's advice.
Taking Tofajak-IN XR 11 mg Tablet with ritonavir may increase the blood levels of Tofajak-IN XR 11 mg Tablet.
How to manage the interaction:
Although there is a possible interaction between Tofajak-IN XR 11 mg Tablet and Ritonavir, but it can be taken together if prescribed by your doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Tofajak-IN XR 11 mg Tablet:
Taking Tofajak-IN XR 11 mg Tablet with Cladribine may increase the risk of developing serious infections.
How to manage the interaction:
Although taking Cladribine and Tofajak-IN XR 11 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Taking Tofajak-IN XR 11 mg Tablet with Cladribine may increase the risk of developing serious infections.
How to manage the interaction:
Although taking Cladribine and Tofajak-IN XR 11 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
TofacitinibBasiliximab
Severe
How does the drug interact with Tofajak-IN XR 11 mg Tablet:
Basiliximab can enhance the immune-suppressing effects of Tofajak-IN XR 11 mg Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between Tofajak-IN XR 11 mg Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Basiliximab can enhance the immune-suppressing effects of Tofajak-IN XR 11 mg Tablet which increases risk of infections.
How to manage the interaction:
There may be a possibility of interaction between Tofajak-IN XR 11 mg Tablet and Basiliximab, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Tofajak-IN XR 11 mg Tablet:
Taking Carfilzomib with Tofajak-IN XR 11 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Co-administration of Tofajak-IN XR 11 mg Tablet with Carfilzomib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Taking Carfilzomib with Tofajak-IN XR 11 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Co-administration of Tofajak-IN XR 11 mg Tablet with Carfilzomib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tofajak-IN XR 11 mg Tablet:
Taking Cyclophosphamide with Tofajak-IN XR 11 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Tofajak-IN XR 11 mg Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
Taking Cyclophosphamide with Tofajak-IN XR 11 mg Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Tofajak-IN XR 11 mg Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Tofajak-IN XR 11 mg Tablet:
Using Tofajak-IN XR 11 mg Tablet together with adalimumab can increase the risk of serious infections
How to manage the interaction:
Although taking Tofajak-IN XR 11 mg Tablet and Adalimumab together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Using Tofajak-IN XR 11 mg Tablet together with adalimumab can increase the risk of serious infections
How to manage the interaction:
Although taking Tofajak-IN XR 11 mg Tablet and Adalimumab together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Drug-Food Interactions
TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofajak-IN XR 11 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofajak-IN XR 11 mg Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofajak-IN XR 11 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofajak-IN XR 11 mg Tablet, as it can lead to an interaction.
Product Substitutes
Alcohol
Caution
It is not known if alcohol interacts with Tofajak-IN XR 11 mg Tablet , so please consult a doctor.
Pregnancy
Unsafe
Tofajak-IN XR 11 mg Tablet must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Tofajak-IN XR 11 mg Tablet and for 4 weeks after discontinuation.
Breast Feeding
Unsafe
Avoid breastfeeding while taking Tofajak-IN XR 11 mg Tablet . Please consult a doctor if you have any concerns.
Driving
Safe
Tofajak-IN XR 11 mg Tablet generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.
Liver
Caution
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Tofajak-IN XR 11 mg Tablet is not recommended for patients with severe liver problems.
Kidney
Caution
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Unsafe
Tofajak-IN XR 11 mg Tablet is not recommended for children below 18 years as safety and effectiveness were not established.
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