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  3. TOPAMED 100MG TABLET

TOPAMED 100MG TABLET, Pack of 10 TABLETS
TOPAMED 100MG TABLET, Pack of 10 TABLETS
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
TOPAMED 100MG TABLET is primarily indicated in the treatment of epilepsy and it can also be taken to prevent migraine. It contains Topiramate, which works by controlling the electrical activity of the brain. Thereby, it controls seizures and relieves the symptoms of migraine. It may cause side effects such as feeling sleepy, dizziness, diarrhoea and feeling sick. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

TOPIRAMATE-100MG

Manufacturer/Marketer :

Icon Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About TOPAMED 100MG TABLET

TOPAMED 100MG TABLET belongs to a group of medicines called “antiepileptic (AED)/ anticonvulsant agent' that is primarily indicated in the treatment of epilepsy (Monotherapy and Adjunctive therapy) and It can also be taken to prevent migraine. Epilepsy is a chronic disorder that is responsible for causing unprovoked, recurrent seizures in the body. A seizure is a sudden attack in the brain that makes a person lose control of their actions. Migraine is a mental condition that often causes intense or debilitating headaches with difficulty speaking, nausea, vomiting, and sensitivity to light or sound.

TOPAMED 100MG TABLET is responsible for restoring the balance of neural activity by diminishing the spread of seizure movement in the brain. By controlling the electrical activity of the brain, it controls seizures and relieves the symptoms of migraine. Take TOPAMED 100MG TABLET in an empty stomach without food with one glass of water. TOPAMED 100MG TABLET is only available on prescription. It comes as tablets or capsules intended to be taken by mouth only. Swallow the medication as a whole without crushing or breaking it. TOPAMED 100MG TABLET doses are sometimes advised according to the weight of children so the doctor will change the dose if the child gains or lose weight.

The possible side effects of topiramate include feeling sleepy, dizziness, diarrhoea and feeling sick. Some of the side effects do not even require medical attention and these are usually mild and go away by themselves. Consult with the doctor if any of these side effects continue or get worse with time.

The use of $mame is restricted in persons who are hypersensitive to it, so tell your doctor if you have any allergy to any of the chemical constituents present in this medicine. Tell your doctor if you ever had or already dealing with diarrhoea, glaucoma, metabolic acidosis, lung disease, breathing problems, liver disease, a blood disorder called acute porphyria etc. If a woman is pregnant or planning to pregnant then they should tell their doctor as the use of this medicine during pregnancy may increase the risk of cleft lip and/or cleft palate which is a birth defect in the newborn that may develop during early pregnancy.

Uses of TOPAMED 100MG TABLET

Treatment of Epilepsy, Migraine.

Directions for Use

Tablet: It can be taken irrespective of meals. Swallow the tablet as a whole with a glass of water. Do not chew the tablet. Sprinkle capsule: You may swallow the capsule as a whole or you may open the capsule and sprinkle the entire contents on a teaspoon of soft food. Drink fluids immediately after eating this medicine and food mixture to make sure it is swallowed. Do not store this mixture for later use.

Medicinal Benefits

TOPAMED 100MG TABLET is an antiepileptic (AED) medicine that is used to treat epilepsy in mono or adjunctive therapy and migraine. In Monotherapy epilepsy, TOPAMED 100MG TABLET is suggested for patients above 2 years of age with partial-onset or primary generalized tonic-clonic seizures. In Adjunctive therapy epilepsy, TOPAMED 100MG TABLET is suggested in patients of 2 to 16 years of age with partial-onset seizures or primary generalized tonic-clonic seizures while in patients more than 2 years of age, TOPAMED 100MG TABLET is suggested in patients with seizures associated with Lennox-Gastaut syndrome (LGS). In migraine, TOPAMED 100MG TABLET is suggested for prophylaxis of migraine. TOPAMED 100MG TABLET works by blocking the voltage-dependent sodium and calcium channels and increasing the inhibitory actions of GABA. In epilepsy, TOPAMED 100MG TABLET controls the uncontrolled activity of nerves in the brain and thus prevents or controls seizures. While in migraine, TOPAMED 100MG TABLET tranquilizes the overactive nerve cells in the brain that are responsible for causing migraine.

How TOPAMED 100MG TABLET Works

TOPAMED 100MG TABLET is responsible for restoring the balance of neural activity by diminishing the spread of seizure movement in the brain. By controlling the electrical activity of the brain, it controls seizures and relieves the symptoms of migraine.

Storage

Store in a cool and dry place away from sunlight
Side effects of Topamed 100mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

What if I have taken an overdose of TOPAMED 100MG TABLET

Do not take more than the prescribed dose of TOPAMED 100MG TABLET as it may cause overdose. The symptoms of overdose include drowsiness, blurred vision, speech disturbance, convulsions (fits), double vision, abnormal coordination, stupor (a state of insensibility or near-unconsciousness), stomach pain, low blood pressure, lethargy, mentation impaired, depression, agitation and dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

TOPAMED 100MG TABLET may cause a congenital disability called cleft lip in unborn baby, so the use of this medicine is not allowed in pregnant females. TOPAMED 100MG TABLET may increase the body temperature and reduce sweating, so one should report it to the doctor if they are noticing decreased sweating and hot, dry skin. TOPAMED 100MG TABLET may enhance the level of acid in the blood so one should tell their doctor if they have irregular heartbeats or loss of hunger. Before taking TOPAMED 100MG TABLET, tell the doctor if you have diarrhoea, metabolic acidosis, eye problems, liver disease. TOPAMED 100MG TABLET may affect the working of contraceptives that include the combined pill, vaginal ring, patches,progestogen-only contraceptive pill, and emergency contraception. So, one should tell their doctor if they are using any contraceptives to prevent pregnancy.

Drug-Drug Interactions

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TopiramateMethazolamide
Severe
TopiramatePimozide
Severe

Drug-Drug Interactions

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TopiramateMethazolamide
Severe
How does the drug interact with Topamed 100mg Tablet:
Combining Topamed 100mg Tablet with Methazolamide can increase the risk of negative side effects.

How to manage the interaction:
Although there is a possible interaction between Methazolamide and Topamed 100mg Tablet, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include problems with your body's acid levels, not feeling hungry, an irregular heartbeat, breathing fast, kidney stones, weak bones, decreased sweating, feeling too hot, drinking more fluids than usual, or having stomach pain. Don't hesitate to reach out to your doctor if you experience any of these. Do not stop using any medications without a doctor's advice.
TopiramatePimozide
Severe
How does the drug interact with Topamed 100mg Tablet:
When Pimozide is taken with Topamed 100mg Tablet, it can cause the body to process Pimozide faster.

How to manage the interaction:
Although taking Pimozide and Topamed 100mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting your doctor.
TopiramateDicyclomine
Severe
How does the drug interact with Topamed 100mg Tablet:
Co-administration of Dicyclomine with Topamed 100mg Tablet may worsen effects like increased body temperature and sweating.

How to manage the interaction:
If you have to use Dicyclomine and Topamed 100mg Tablet together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. Drink plenty of fluids during warm weather and when exercising and contact a doctor if you have decreased sweating or a fever. You may also experience drowsiness, dizziness, or lightheadedness when taking these medications together. Do not discontinue the medication without consulting a doctor.
TopiramateZonisamide
Severe
How does the drug interact with Topamed 100mg Tablet:
Coadministration of Topamed 100mg Tablet with Zonisamide can increase the risk or severity of Zonisamide side effects like metabolic acidosis (elevated levels of acid in the blood) and kidney stones.

How to manage the interaction:
Taking Topamed 100mg Tablet with Zonisamide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in confusion, fast heartbeat, fatigue, nausea, vomiting, long and deep breaths, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
TopiramatePromethazine
Severe
How does the drug interact with Topamed 100mg Tablet:
Taking promethazine with Topamed 100mg Tablet can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although there is an interaction between promethazine and amiodarone, they can be taken together if prescribed by your doctor. However, contact a doctor if you experience drowsiness, dizziness, or lightheadedness. Do not discontinue any medications without consulting a doctor.
TopiramateHydroxyzine
Severe
How does the drug interact with Topamed 100mg Tablet:
Topamed 100mg Tablet can induce elevated body temperature and reduced sweating, which can be exacerbated when taken with hydroxyzine.

How to manage the interaction:
Although taking Hydroxyzine and Topamed 100mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. Drink plenty of water when it's hot out and while you're exercising and get medical assistance if you have reduced perspiration or a fever. Consult a doctor if you experience drowsiness, dizziness, or lightheadedness. Do not stop using any medications without talking to a doctor.
TopiramateMeclizine
Severe
How does the drug interact with Topamed 100mg Tablet:
Taking Topamed 100mg Tablet with meclizine can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although there is a interaction between Meclizine and Topamed 100mg Tablet, but it can be taken together if prescribed by your doctor. However, if you experience drowsiness, dizziness, or lightheadedness, increased body temperature and decreased sweating contact your doctor. Do not stop using any medications without a doctor's advice.
TopiramateAmoxapine
Severe
How does the drug interact with Topamed 100mg Tablet:
Topamed 100mg Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like amoxapine.

How to manage the interaction:
Taking Topamed 100mg Tablet with Amoxapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness consult your doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced perspiration or a fever. Do not discontinue any medications without first consulting your doctor.
TopiramateAripiprazole
Severe
How does the drug interact with Topamed 100mg Tablet:
Topamed 100mg Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like aripiprazole.

How to manage the interaction:
Co-administration of Aripiprazole with Topamed 100mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, consult the doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced sweating or a fever. Do not discontinue any medications without consulting a doctor.
TopiramateDexchlorpheniramine
Severe
How does the drug interact with Topamed 100mg Tablet:
Co-administration of dexchlorpheniramine with Topamed 100mg Tablet can increase the risk of Topamed 100mg Tablet side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Dexchlorpheniramine with Topamed 100mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience decreased sweating, fever, or drowsiness, contact your doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a balanced diet that consists of good fats, proteins, carbohydrates, vegetables, and fruit which helps the body and brain to work properly and keep a person healthy and energetic.

  • Fatigue is one of the primary reasons that trigger seizures in the body, so sleeping properly can help in relaxing the brain.

  • One should avoid the consumption of alcohol as it can trigger seizures in patients. Even one or two glasses can trigger epilepsy and worsen the side effects of TOPAMED 100MG TABLET.

  • Keep yourself happy and avoid taking emotional stress as stress causes seizures. Persons who maintain healthy stress levels have reported that they have responded well to the medicine.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

TOPAMED 100MG TABLET Substitute

Substitutes safety advice

  • Topamac 100 mg Tablet 10's

    by Others

    ₹47.66per tablet

  • Topaz 100 Tablet 15's

    by AYUR

    ₹26.04per tablet

  • Topirol 100 Tablet 10's

    by Others

    ₹30.15per tablet

  • Nextop 100 Tablet 10's

    by Others

    ₹27.54per tablet

  • Leptomate 100 Tablet 10's

    by AYUR

    ₹15.39per tablet

Product Substitutes

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Alcohol

Caution

Do not consume alcohol while taking TOPAMED 100MG TABLET as alcohol can worsen the side effects of the TOPAMED 100MG TABLET including sleepiness and dizziness

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Pregnancy

Unsafe

TOPAMED 100MG TABLET is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of the cleft lip that is a congenital disability in the unborn baby.

bannner image

Breast Feeding

Caution

Caution is advised when TOPAMED 100MG TABLET is using in nursing mothers as this medicine may pass into breast milk.

bannner image

Driving

Caution

Some persons may continue to face unpredictable seizures even after taking TOPAMED 100MG TABLET and this medicine also affects thinking and motor skills and may affect vision. So patients should take caution before engaging in any activity including driving or operating any machine.

bannner image

Liver

Caution

TOPAMED 100MG TABLET should be used with caution in patients with liver disease as the dosage needs to be reduced in patients dealing with liver disease.

bannner image

Kidney

Caution

TOPAMED 100MG TABLET should be used with caution in patients with kidney disease as the dosage needs to be reduced in patients dealing with kidney disease.

bannner image

Children

Safe if prescribed

TOPAMED 100MG TABLET is safe to use in children above 2 years only if prescribed by the doctor.

Have a query?

FAQs

TOPAMED 100MG TABLET is primarily indicated in the treatment of epilepsy (Monotherapy and Adjunctive therapy), and it can also be used to prevent migraine.

Seizures can happen when the brain cells are not working properly or working faster than normal. TOPAMED 100MG TABLET slows down these electrical signals to stop seizures.

No, you should take rest after taking this medicine as this medicine affects the thinking ability and vision of a person so avoid doing any task that requires mental alertness.

TOPAMED 100MG TABLET acts by decreasing the spread of seizure activity in the brain. It also restores the normal balance of neurons which in turn calms the brain. In epilepsy, cells present in the brain talk to each other by generating electric signals. When these cells fail to work properly or working faster than normal then it causes seizures. TOPAMED 100MG TABLET slows down these electrical signals and thus prevents or controls seizures. While in migraine, TOPAMED 100MG TABLET tranquilizes the overactive nerve cells in the brain that are responsible for causing migraine.

Yes, the use of TOPAMED 100MG TABLET is safe for long time use if suggested by the doctor.

Yes, TOPAMED 100MG TABLET may affect the working of contraceptives that include the combined pill, vaginal ring, patches,progestogen-only contraceptive pill, and emergency contraception. Tell your doctor if you are using any type of contraceptives as the doctor may suggest using different types of contraceptives or combined hormonal contraceptives.

No, TOPAMED 100MG TABLET does not affect fertility.

Generally, one should avoid consuming alcohol while taking TOPAMED 100MG TABLET as it may make a person feel sleepy or tired and can cause seizures in some people with epilepsy.

Yes, studies have shown that TOPAMED 100MG TABLET can cause hair loss (alopecia), but it is not a common side effect. If this happens, please consult your doctor and seek appropriate treatment.

Feeling sleepy is one of the most common side effects of TOPAMED 100MG TABLET. It does not require medical attention, is usually mild and goes away over time. Consult the doctor if any of these side effects continue or worsen with time.

Do not stop taking TOPAMED 100MG TABLET abruptly unless your doctor instructs you to. If you're using it to prevent migraines, your condition may worsen temporarily after you stop taking it. If you are using TOPAMED 100MG TABLET for epilepsy, you may get seizures when you stop taking it. To prevent these withdrawal symptoms, your doctor may gradually reduce the dose of your TOPAMED 100MG TABLET if required.

It depends on the medical condition you are being treated with TOPAMED 100MG TABLET and response to the treatment.

No, TOPAMED 100MG TABLET is not intended to treat anxiety.

The severe side effects caused by TOPAMED 100MG TABLET include signs of glaucoma (blurred vision, difficulty seeing, and eye pain), kidney stones and a kidney infection (pain in your back, belly, or side, a burning sensation when you pee, or cloudy or smelly pee), metabolic acidosis (feeling sleepy, losing your appetite, and having an irregular heartbeat), and not sweating (especially in children). If this happens, consult your doctor immediately and seek medical attention.

Taking valproic acid when you are also taking TOPAMED 100MG TABLET can cause your body temperature to drop to less than 95°F or 350C or cause tiredness, confusion, or coma. Taking these medicines may also raise the levels of ammonia in your blood. So, do not take these medications together. If you are required to, your doctor may guide you in taking them appropriately.

TOPAMED 100MG TABLET is safe for children above two years of age only if prescribed by the doctor.

Weight loss and loss of appetite (anorexia) were two of the most commonly reported side effects. If you experience significant changes, seek medical advice from your healthcare professional.

The possible side effects of topiramate include feeling sleepy, dizziness, diarrhoea and feeling sick. Some side effects do not require medical attention; they are usually mild and go away alone. Consult the doctor if any of these side effects continue or worsen with time.

Country of origin

India

Manufacturer/Marketer address

Icon Life Sciences, Div. Of Mesmer Pharmaceuticals, No.202/6, Lane In.30, Phase-II, IDA, Cherlapally, Hyderabad, 500 051 AP
Other Info - TOP0335

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jan 1, 2025 | 2:49 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020844s041lbl.pdf
  2. https://www.medicines.org.uk/emc/medicine/6768#gref
  3. https://www.nhs.uk/medicines/topiramate/
  4. https://www.drugs.com/mtm/topiramate.html
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