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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Topnerve-B Capsule is used to treat and prevent vitamin B1 deficiency. It is also useful in improving mental health symptoms in people addicted to alcoholism and pain caused by diabetic neuropathy (nerve damage due to diabetes). It is also used to treat Beriberi disease; a condition caused due to prolonged vitamin B1 deficiency. It contains Benfotiamine, a synthetic form of Vitamin B1 or Thiamine, which is coverted into thiamine by the body. It helps in delivering essential nutrients to the nerves. It may cause common side effects such as nausea, diarrhoea, skin rash and stomach discomfort. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

BENFOTIAMINE-100MG

Manufacturer/Marketer :

Vasu Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Topnerve-B Capsule

Topnerve-B Capsule is a vitamin and dietary supplement primarily used to treat and prevent vitamin B1 deficiency. Topnerve-B Capsule is also useful in improving mental health symptoms in people addicted to alcoholism and pain caused by diabetic neuropathy (nerve damage due to diabetes). It is also used to treat Beriberi disease; a condition caused due to prolonged vitamin B1 deficiency.

Topnerve-B Capsule contains 'Benfotiamine', a synthetic form of Vitamin B1 or Thiamine. Some people do not get adequate levels of Vitamin B1 from food sources. Topnerve-B Capsule helps in treating such nutritional deficiencies through Vitamin B1 supplements. The body turns benfotiamine into thiamine. Thiamine helps in delivering essential nutrients to the nerves.

Your doctor will decide the dose and duration based on your medical condition. Common side effects of Topnerve-B Capsule include nausea, diarrhoea, skin rash and stomach discomfort. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any other medications, including other vitamins, before starting Topnerve-B Capsule . Please tell your doctor if you are allergic to Topnerve-B Capsule or its components. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Topnerve-B Capsule is not known to affect driving; however, if you notice any symptoms, please seek medical advice. Avoiding alcohol is recommended to rule out any possibility of side effects. Topnerve-B Capsule is not recommended in children below 12 years of age.

Uses of Topnerve-B Capsule

Topnerve-B Capsule is used in the treatment of Vitamin B1 deficiency, beriberi disease, diabetic neuropathy and alcohol dependence. The detailed uses of Topnerve-B Capsule are as follows:
•Energy Metabolism: Topnerve-B Capsule plays an essential role in converting carbohydrates into energy, making it particularly vital for athletes and individuals engaged in energy-demanding activities.
•Nerve Function: Topnerve-B Capsule supports healthy nerve cells and is frequently utilized in the treatment of neuropathies and other nerve-related disorders.
•Cardiovascular Health: Topnerve-B Capsule is crucial for heart health, ensuring proper cardiac function and metabolic processes within heart cells.
•Preventing Neurological Disorders: Topnerve-B Capsule is commonly suggested to individuals with alcohol dependence to prevent conditions like Wernicke-Korsakoff syndrome, a severe neurological disorder.
•Digestive Health: Topnerve-B Capsule promotes the production of essential enzymes, aiding the digestive system, improving appetite, and supporting better digestion.

Directions for Use

Swallow the medicine as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Topnerve-B Capsule contains 'Benfotiamine', which is used to treat and prevent vitamin B1 deficiency. It is a lab-made version of vitamin B1, also called thiamine. Topnerve-B Capsule is a dietary supplement that improves mental health symptoms in people addicted to alcoholism and pain caused by diabetic neuropathy (nerve damage due to diabetes). Thiamine is used to treat beriberi disease, a condition caused due to prolonged vitamin B1 deficiency. The body turns benfotiamine into thiamine. Thiamine helps in delivering essential nutrients to the nerves. Topnerve-B Capsule may also improve symptoms of Alzheimer's disease and arthritis. However, there is no scientific evidence to support these uses.

How Topnerve-B Capsule Works

Topnerve-B Capsule contains 'Benfotiamine', a synthetic form of Vitamin B1 or Thiamine. Some people do not get adequate levels of Vitamin B1 from food sources. Topnerve-B Capsule helps in treating such nutritional deficiencies through Vitamin B1 supplements. The body turns benfotiamine into thiamine. Thiamine helps in delivering essential nutrients to the nerves.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Topnerve-B Capsule

Do not take more than the suggested dose of Topnerve-B Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Let your doctor know if you use any other medications, including vitamins, before starting Topnerve-B Capsule . Let your doctor know if you have any liver or kidney diseases before starting Topnerve-B Capsule . Please consult your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother. Topnerve-B Capsule is not known to affect driving; however, if you notice any symptoms, please seek medical advice. Topnerve-B Capsule is not recommended in children below 12 years of age.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Topnerve-B Capsule:
Trimethoprim may decrease the blood levels and effects of Topnerve-B Capsule.

How to manage the interaction:
Although there is a possible interaction between Topnerve-B Capsule and Trimethoprim, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.
How does the drug interact with Topnerve-B Capsule:
Sulfadiazine may decrease the blood levels and effects of Topnerve-B Capsule.

How to manage the interaction:
Although there is a possible interaction between Topnerve-B Capsule and Sulfadiazine, you can take these medicines together if prescribed by your doctor.
How does the drug interact with Topnerve-B Capsule:
Co-administration of Topnerve-B Capsule with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Topnerve-B Capsule and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Topnerve-B Capsule:
Coadministration of Topnerve-B Capsule and Carbamazepine may reduce the blood levels of Topnerve-B Capsule.

How to manage the interaction:
Although there is a possible interaction between Topnerve-B Capsule and Carbamazepine, you can take these medicines together if prescribed by your doctor. However, if your condition changes or you experience loss of seizure control, contact your doctor.
How does the drug interact with Topnerve-B Capsule:
Coadministration of Topnerve-B Capsule and Fluorouracil may increase the effects of Fluorouracil and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Topnerve-B Capsule and Fluorouracil, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.
How does the drug interact with Topnerve-B Capsule:
Coadministration of Topnerve-B Capsule and Cholestyramine may interfere with the absorption of Topnerve-B Capsule.

How to manage the interaction:
Although taking Cholestyramine and Topnerve-B Capsule together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Topnerve-B Capsule:
Coadministration of Topnerve-B Capsule with Chloramphenicol can impair absorption and increase the levels of Topnerve-B Capsule which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Topnerve-B Capsule with Chloramphenicol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Topnerve-B Capsule:
Coadministration of Topnerve-B Capsule with Neomycin can impair the absorption of Topnerve-B Capsule and increase its levels which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Topnerve-B Capsule with Neomycin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include Vitamin B1-rich foods like beans, legumes, dairy products (such as yoghurt), eggs, meat, poultry, fish, nuts, seeds, thiamine-enriched breakfast cereals and whole grains in your diet

  • Taking vegetables like acorn squash, asparagus, beet greens, brussels sprouts and spinach can help you cope with Vitamin B1 deficiency.

  • Manage stress, eat healthily, drink plenty of water, exercise regularly and get plenty of sleep.

  • Avoid or limit the intake of alcohol and caffeine.

Habit Forming

No

Therapeutic Class

VITAMINS
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Alcohol

Caution

Avoid or limit taking alcohol while using Topnerve-B Capsule to prevent any adverse reactions.

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Pregnancy

Caution

Topnerve-B Capsule is only recommended for use during pregnancy by your doctor when benefit outweighs the risk.

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Breast Feeding

Caution

Please consult your doctor before taking Topnerve-B Capsule ; your doctor will decide whether Topnerve-B Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

It is unknown whether Topnerve-B Capsule affects driving, however, if you notice any symptoms, please consult your doctor.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Topnerve-B Capsule .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Topnerve-B Capsule .

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Children

Unsafe

Topnerve-B Capsule is not recommended in children below 12 years of age.

Have a query?

FAQs

Topnerve-B Capsule is used to treat Vitamin B1 deficiency, beriberi disease, diabetic neuropathy and alcohol use disorder.

Topnerve-B Capsule is a dietary supplement and contains 'Benfotiamine'. It is a lab-made version of vitamin B1, also called thiamine. The body turns benfotiamine into thiamine. Thiamine helps in delivering essential nutrients to the nerves and treats vitamin B1 deficiency and beriberi disease.

Vitamin B1 deficiency is caused when your body does not have adequate levels of Vitamin B1 or Thiamine. This deficiency is commonly found in alcoholics, people with poor diet and malabsorption condition. It is also common in children with congenital heart diseases. People who undergo dialysis treatment may also develop vitamin B1 deficiency.

Topnerve-B Capsule is safe to use during diabetic conditions since it shows positive effects on conditions caused by low blood sugar levels. Your doctor will advise on how you should use Topnerve-B Capsule if you have diabetes.

Topnerve-B Capsule does not usually cause any allergies. However, if you notice any side effects like skin rash, please consult your doctor. Also, some Vitamin B1 tablets may contain components like lactose monohydrate. If you are lactose intolerant, let your doctor know about it.

Topnerve-B Capsule (Benfotiamine) and Thiamine (Vitamin B1) are closely related but not identical. Topnerve-B Capsule is a lipid-soluble derivative of Thiamine, designed to enhance absorption and bioavailability. While Thiamine is the natural, water-soluble form of Vitamin B1, Topnerve-B Capsule is mainly used to address specific health concerns, such as vitamin B1 deficiency, diabetic neuropathy, and alcoholism-related nerve damage.

Topnerve-B Capsule is a vitamin supplement used to treat and prevent Vitamin B1 deficiency, including conditions like alcoholism-related nerve damage, and diabetic neuropathy. It's also effective in managing mental health symptoms and preventing Beriberi disease. Benfotiamine converts to thiamine in the body, delivering essential nutrients to nerves.

Topnerve-B Capsule may cause weight gain in some cases, but not everyone who takes it will experience this side effect. A healthy lifestyle, including a balanced diet and regular exercise, can help minimize the risk of weight gain.

Topnerve-B Capsule is generally considered safe, but like any supplement, it can cause some side effects in a few cases. Possible side effects may include skin rash, nausea, stomach discomfort, diarrhea, hair loss, weight gain, body odor, and a decrease in blood pressure. Please note that these side effects are relatively rare and do not affect everyone who takes it. If you experience any persistent or worsening side effects, it's essential to consult your doctor for guidance.

Country of origin

India

Manufacturer/Marketer address

967/4 G.I.D.C., Makarpura, Vadodara – 390010, Gujarat, India.
Other Info - TOP0376

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