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compositionComposition:EVEROLIMUS-5MG
prescription
Prescription Medicine
info
Torinat 5 Tablet 7's
Torinat 5 Tablet 7's is used to treat cancer and to prevent organ rejection. It contains Everolimus which works by stopping cancer cells from reproducing and decreasing the activity of the immune system. In some cases, this medicine may cause side effects such as weakness, infection, cough, diarrhoea, fever, and fatigue. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

EVEROLIMUS-5MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Torinat 5 Tablet 7's

Torinat 5 Tablet 7's belongs to the group of medicine called ‘anti-cancer’. It is primarily used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer. Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen. Pancreatic cancer is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices that help break down food and the hormones which help in controlling blood sugar levels. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. 

Torinat 5 Tablet 7's contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take Torinat 5 Tablet 7's as prescribed by your doctor. You are advised to take Torinat 5 Tablet 7's for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience weakness, infection, sinus inflammation, cough, diarrhea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of Torinat 5 Tablet 7's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue taking Torinat 5 Tablet 7's for as long as your doctor has prescribed. If you are known to be allergic to Torinat 5 Tablet 7's or any other medicines, please tell your doctor. Do not take Torinat 5 Tablet 7's if you are pregnant or planning for pregnancy as Torinat 5 Tablet 7's may harm the unborn baby. Torinat 5 Tablet 7's should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. Torinat 5 Tablet 7's causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Uses of Torinat 5 Tablet 7's

Torinat 5 Tablet 7's is used in the treatment of Breast cancer, pancreatic cancer, lung cancer, and kidney cancer. The detailed uses of Torinat 5 Tablet 7's are as follows:

  • Cancer Treatment: Torinat 5 Tablet 7's is used for various cancers, including advanced hormone receptor-positive breast cancer, pancreatic neuroendocrine tumors, and neuroendocrine tumors of the stomach, lungs, and intestines that cannot be treated surgically.
  • Kidney Cancer Management: Torinat 5 Tablet 7's is used in advanced renal cell carcinoma when other treatments have failed.
  • Organ Transplant Rejection Prevention: Torinat 5 Tablet 7's helps prevent rejection in kidney and liver transplant patients by suppressing the immune system.
  • Tuberous Sclerosis Complex (TSC)-Related Tumors: Torinat 5 Tablet 7's is indicated for treating certain benign tumors associated with TSC, such as subependymal giant cell astrocytoma (SEGA) and renal angiomyolipoma.
  • Immunosuppressive Therapy: As an mTOR inhibitor, Torinat 5 Tablet 7's reduces the activity of immune cells, helping manage autoimmune conditions and prevent transplant-related complications.

Key Benefits

Torinat 5 Tablet 7's is indicated to the patients dealing with breast cancer, pancreatic cancer, lung cancer, kidney cancer and stomach/ intestinal cancer. Cancer of this type tends to spread quickly in other parts of the body. Torinat 5 Tablet 7's travels through the bloodstream and effectively destroys cancerous cells and other parts of the body. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells. Besides this, it is also effective in people with genetic disorders to treat some types of tumors in the brain or kidney.

Side effects of Torinat 5 Tablet
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • Stay hydrated by taking fluids like water, juices and soups etc.
  • Eat fruits and vegetables which contain vitamins.
  • Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
  • Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
  • Regular exercise like walking, jogging is helpful.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
  • Eat a healthy balanced diet.
  • Reduce stress with relaxation techniques such as yoga or meditation.
  • Keep track of your menstrual cycle any irregularities.
  • Have regular check ups to exclude other health problems.
  • Exercise but do not exercise to the extent of overheating.
  • Hydrate well, eat well (particularly iron and vitamins).
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.

Directions for Use

  • Torinat 5 Tablet 7's can be taken with or without food.
  • It is recommended to take Torinat 5 Tablet 7's once daily at the same time each day or as advised by your doctor.
  • Swallow Torinat 5 Tablet 7's as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Torinat 5 Tablet 7's Works

Torinat 5 Tablet 7's contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Torinat 5 Tablet 7's to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Torinat 5 Tablet 7's is belonging to pregnancy C category. It is not safe in pregnancy as it may causes harm to the unborn baby. Do not conceive a baby while taking Torinat 5 Tablet 7's.

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Breast Feeding

Unsafe

Torinat 5 Tablet 7's should not be taken by breastfeeding mothers as it may harm to the new-born baby.

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Driving

Caution

Torinat 5 Tablet 7's may cause tiredness (fatigue), do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Torinat 5 Tablet 7's should be taken with caution in patients dealing with liver disease. The doctor may adjust the dose according to the medical condition of the patient.

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Kidney

Caution

Torinat 5 Tablet 7's is likely unsafe in patients with severe kidney disease as it may cause kidney failure which can be dangerous, use Torinat 5 Tablet 7's only when prescribed by a doctor.

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Children

Unsafe

Torinat 5 Tablet 7's is not recommended for children below 18 years as the safety and effectiveness were not established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Torinat 5 Tablet 7's. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Torinat 5 Tablet 7's in elderly patients. Please consult your doctor.

What if I have taken an overdose of Torinat 5 Tablet 7's

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep, rest well.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

Have a query?

How Soon It Starts Working

The time required for Torinat 5 Tablet 7's to start to work: Torinat 5 Tablet 7's ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Torinat 5 Tablet 7's last: The duration of action for Torinat 5 Tablet 7's is clinically unknown.

What if you forget to take Torinat 5 Tablet 7's

If you miss a dose of Torinat 5 Tablet 7's, take it as soon as possible, but only if it's within six hours of the missed dose. If more than six hours have passed, skip the missed dose and continue your regular schedule.

Storage

• Store in a cool and dry place away from sunlight. • Keep this medicine out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

If you are known to be allergic to Torinat 5 Tablet 7's or any other medicines, please tell your doctor. Torinat 5 Tablet 7's should not be taken in the conditions like liver disease, diabetes and high level of cholesterol. Do not take Torinat 5 Tablet 7's if you have recent surgery, infection and hepatitis B. Torinat 5 Tablet 7's may weaken your immune system, inform your doctor before taking Torinat 5 Tablet 7's. Torinat 5 Tablet 7's may also impair your kidney function. Therefore, monitor your kidney function regularly while taking Torinat 5 Tablet 7's. Torinat 5 Tablet 7's may cause cough, fever and shortness of breathing, thereby inform your doctor while taking your Torinat 5 Tablet 7's. Torinat 5 Tablet 7's may cause skin cancer, if you observe night sweating, weight loss, or change in color and size of the mole inform your doctor. Do not take Torinat 5 Tablet 7's if you are pregnant or planning for pregnancy as Torinat 5 Tablet 7's may harm the unborn baby. Torinat 5 Tablet 7's should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. Torinat 5 Tablet 7's causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Drug-Drug Interactions

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Drug-Drug Interaction: Torinat 5 Tablet 7's may have interaction with antifungal medicines (ketoconazole, itraconazole, voriconazole, fluconazole), antibiotics (clarithromycin, telithromycin, erythromycin), anti-HIV medicines (ritonavir, efavirenz), blood pressure-lowering medicines (ramipril, verapamil, diltiazem), medicines for heart disease (dronedarone), medicines for decreasing growth of abnormal cells (imatinib), medicines for fits/ epilepsy (phenytoin, carbamazepine, phenobarbital).

Drug-Food Interaction: Avoid grapefruits and grapefruit juice.

Drug-Disease Interaction: Torinat 5 Tablet 7's should not be given to the patients with liver disease, kidney disease, diabetes, high level of cholesterol and infections.

EverolimusVoclosporin
Severe
EverolimusIodixanol
Severe

Drug-Drug Interactions

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EverolimusVoclosporin
Severe
How does the drug interact with Torinat 5 Tablet:
Using voclosporin together with Torinat 5 Tablet may increase the risk of serious infections.

How to manage the interaction:
Although taking Torinat 5 Tablet and Voclosporin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusIodixanol
Severe
How does the drug interact with Torinat 5 Tablet:
Injections of Iodixanol and related contrast agents can occasionally cause kidney damage and mixing it with Torinat 5 Tablet, may enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Torinat 5 Tablet and Iodixanol, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult your doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without talking to a doctor.
EverolimusAprepitant
Severe
How does the drug interact with Torinat 5 Tablet:
Coadministration of Torinat 5 Tablet with Aprepitant blood levels may considerably increase the blood level of the aprepitant, which increases the severity of serious side effects (pneumonitis - inflammation of the lungs, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although co-administration of Aprepitant and Torinat 5 Tablet can lead to an interaction, it can be taken if prescribed by a doctor. Consult a doctor if you suffer any symptoms, including bleeding, anemia, oral ulcers, infection, lung problems (shortness of breath, persistent cough, tiredness). Without consulting a doctor, never stop taking medicines.
EverolimusGriseofulvin
Severe
How does the drug interact with Torinat 5 Tablet:
When Torinat 5 Tablet is taken with Griseofulvin, it may decrease the blood levels of Torinat 5 Tablet, which may make Torinat 5 Tablet less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Torinat 5 Tablet and Griseofulvin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EverolimusTeriflunomide
Severe
How does the drug interact with Torinat 5 Tablet:
When Torinat 5 Tablet is used with teriflunomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Torinat 5 Tablet and Teriflunomide, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusFosaprepitant
Severe
How does the drug interact with Torinat 5 Tablet:
When Torinat 5 Tablet and Fosaprepitant are taken together, can increase the levels of Torinat 5 Tablet in the body. This can increase the risk of serious side effects like serious.

How to manage the interaction:
Taking Torinat 5 Tablet with Fosaprepitant together can result in an interaction, but it can be taken if a doctor has advised it. If you're having symptoms like mouth sores, unusual bleeding, shortness of breath, tiredness, or coughing it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
EverolimusItraconazole
Severe
How does the drug interact with Torinat 5 Tablet:
Co-administration of Torinat 5 Tablet and itraconazole can increase the blood levels of Torinat 5 Tablet leading to serious side effects (pneumonitis - inflammation of the lungs, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Itraconazole and Torinat 5 Tablet may interact, but if a doctor prescribes them, you can still take them. If you have an infection, oral ulcers, pale skin, or bleeding, consult a doctor right once. Never discontinue taking a medication without consulting a doctor.
EverolimusIodamide
Severe
How does the drug interact with Torinat 5 Tablet:
Injections of Iodamide and related contrast agents can occasionally cause kidney damage, and mixing it with Torinat 5 Tablet, may enhance the risk.

How to manage the interaction:
Although taking Torinat 5 Tablet and Iodamide together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without talking to a doctor.
EverolimusNelfinavir
Severe
How does the drug interact with Torinat 5 Tablet:
Taking Torinat 5 Tablet with nelfinavir can considerably raise blood levels of Torinat 5 Tablet, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although taking Torinat 5 Tablet and Nelfinavir together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without a doctor's advice.
EverolimusKetorolac
Severe
How does the drug interact with Torinat 5 Tablet:
Coadministration of Torinat 5 Tablet with ketorolac may increase the risk of kidney problems.

How to manage the interaction:
Although taking Ketorolac and Torinat 5 Tablet together can result in an interaction, but it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, pain, weakness, tiredness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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EVEROLIMUS-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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EVEROLIMUS-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Taking Torinat 5 Tablet with grapefruit juice can raise blood levels and enhance the effects of Torinat 5 Tablet. Since the co-administration of Torinat 5 Tablet along with grapefruit juice can lead to an interaction, You should not consume grapefruit juice or eat grapefruits while taking Torinat 5 Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Torinat 5 Tablet 7's is used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer.
Torinat 5 Tablet 7's is an anticancer medicine. It belongs to a group of medicines known as a kinase inhibitor. It works by lowering the blood supply to the tumor, which reduces the growth and spread of cancer cells.
There is no specific duration of treatment with Torinat 5 Tablet 7's. Torinat 5 Tablet 7's is continued till benefit is seen or undesirable toxicity or side effects occur.
You should prevent grapefruit or grapefruit juice while taking Torinat 5 Tablet 7's. This is because taking them together may rise the levels of Torinat 5 Tablet 7's in your blood to toxic levels. Avoid the use of live vaccinations and any probable contact with people who have received live vaccinations.
Torinat 5 Tablet 7's can lead to serious side effects that consist of severe allergic reactions, angioedema (painless swelling under the skin) and kidney failure which can be dangerous and can lead to death. It is possible that you may develop an infection or problems associated to lungs like breathing problems.
It usually takes three to six months for most types of lung cancer to double their size. It will take a long time for lung cancer to reach a size that could be diagnosed in X-Ray.
Torinat 5 Tablet 7's contains Everolimus, which belongs to the group of medicines known as kinase inhibitors.
Regular monitoring is essential when using Torinat 5 Tablet 7's. Your doctor may check your blood tests, blood sugar, blood pressure, and kidney function. They may also adjust your dose based on your response to treatment or any side effects that occur. It's essential to report any changes or concerns to your doctor to ensure safe and effective treatment.
While taking Torinat 5 Tablet 7's, avoiding certain things is essential to ensure your safety. Avoid consuming grapefruit juice and products and St. John's Wort, as they can interact with the medication. Certain antibiotics, antifungals, and medications can also interact with Everolimus, so consult your doctor before taking any new medications. Additionally, consult your doctor before receiving any vaccinations and avoid high-risk activities that may increase the risk of infections and bleeding. It's also important to avoid getting pregnant or fathering a child while taking Everolimus, as well as breastfeeding. Finally, limit your sun exposure to avoid increasing the risk of skin cancer. Always consult your doctor or pharmacist for a comprehensive list of medications and activities to avoid while taking Everolimus.
Before using any medication, including Torinat 5 Tablet 7's, you should know its purpose, usage, safety profile, precautions, and limitations.
Torinat 5 Tablet 7's is administered orally in the form of a tablet. Take Everolimus with or without food, as advised by your doctor. Swallow the tablet whole with water; do not crush, break, or chew it. Note: It's important to follow your doctor's instructions and take Torinat 5 Tablet 7's exactly as prescribed
By regularly monitoring your progress through brain scans and other evaluations, your doctor can determine if Torinat 5 Tablet 7's is effectively shrinking your brain tumor.
Torinat 5 Tablet 7's is indeed considered a cytotoxic medication, but it's a targeted therapy that specifically targets cancer cells and inhibits their growth. It's not a traditional chemotherapy medication, but it can still have side effects and be harmful to healthy cells to some extent. If you have any concerns or questions, please consult your doctor or healthcare team to discuss potential risks and benefits and manage any side effects.
Common side effects of Torinat 5 Tablet 7's may include weakness, infection, sinus inflammation, cough, diarrhoea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of Torinat 5 Tablet 7's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - TOR0613

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