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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Trajenta 5 mg Tablet is used to treat type 2 diabetes in adults along with diet and lifestyle changes. It is used alone or in combination with other drugs to lower blood sugar levels. It contains Linagliptin, which boosts the body's production of insulin (a hormone that controls blood sugar levels). It may cause common side effects such as hypoglycaemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold), and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

LINAGLIPTIN-5MG

Manufacturer/Marketer :

Boehringer Ingelheim India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Trajenta 5 mg Tablet

Trajenta 5 mg Tablet is used to treat type 2 diabetes in adults along with diet and lifestyle changes. It is used alone or in combination with other drugs to lower blood sugar levels. People with type 2 diabetes either do not produce enough insulin, or the insulin produced cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, also known as adult-onset diabetes.

Trajenta 5 mg Tablet contains Linagliptin, which belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by blocking the action of DPP-4, an enzyme that destroys the hormone Incretin. The enzyme 'Incretins' helps produce more insulin only when required and reduces the liver's blood sugar level when not needed. 

The most common side effects of Trajenta 5 mg Tablet are hypoglycaemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold), and headache. Most of these side effects may not require medical attention and resolve gradually overtime. However, if the side effects persist or worsen, consult the doctor.

Do not take Trajenta 5 mg Tablet if you are allergic to any of its components. If you stop taking Trajenta 5 mg Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Trajenta 5 mg Tablet should not be taken if you have severe kidney or liver disease. Please inform your doctor if you have any heart disease or if you are pregnant, planning to get pregnant or breastfeeding.

Uses of Trajenta 5 mg Tablet

Trajenta 5 mg Tablet is used in the treatment of type 2 diabetes mellitus. The detailed uses of Trajenta 5 mg Tablet are as follows:
• Managing Type 2 Diabetes: Trajenta 5 mg Tablet can be used as part of a comprehensive diabetes management plan for individuals with type 2 diabetes, helping to lower blood sugar levels.
• Improving Insulin Sensitivity: Trajenta 5 mg Tablet may help enhance the body's response to insulin, assisting in better glucose metabolism for those with insulin resistance.
• Postprandial Blood Sugar Control: Trajenta 5 mg Tablet can be effective in managing blood sugar spikes that occur after eating, helping to maintain more stable blood glucose levels throughout the day.

Directions for Use

Take Trajenta 5 mg Tablet with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Trajenta 5 mg Tablet is primarily used to treat Type 2 diabetes mellitus. It contains Linagliptin, which belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors used Trajenta 5 mg Tablet is prescribed for type 2 diabetes when diet and exercise alone cannot control blood sugar levels. It works by blocking the action of DPP-4 (an enzyme that destroys the hormone ‘Incretin’). The enzyme ‘Incretins’ helps produce more insulin only when required and reduces the liver's blood sugar level when not needed. Trajenta 5 mg Tablet should not be used in patients with type 1 diabetes and for the treatment of diabetic ketoacidosis. Thus, Trajenta 5 mg Tablet plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.

How Trajenta 5 mg Tablet Works

Trajenta 5 mg Tablet contains Linagliptin, which belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by blocking the action of DPP-4, an enzyme that destroys the hormone Incretin. The enzyme 'Incretins' helps produce more insulin only when required and reduces the liver's blood sugar level when not needed.

Storage

Store in a cool and dry place away from sunlight
Side effects of Trajenta 5 mg Tablet
  • Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
  • Avoid foods with label “partially hydrogenated oils”.
  • Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
  • Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
  • Limit consumption of egg yolks.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
  • Limit alcohol consumption as excessive drinking may raise cholesterol levels.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Exercise for at least 30 minutes most days of the week.
  • Limit alcohol consumption.
  • Consider a low carbohydrate diet that limits grains, starchy vegetables and fruit. Include foods rich in protein and fat.
  • Avoid excess sugar, fatty foods and carbohydrates.
  • Aim for weight loss as it helps to improve cardiovascular health and minimize the risk of complications related to obesity.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.

What if I have taken an overdose of Trajenta 5 mg Tablet

Do not take more than the prescribed dose of Trajenta 5 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Trajenta 5 mg Tablet should not be taken if you are allergic to Trajenta 5 mg Tablet or any of its ingredients. Please inform your doctor if you are pregnant or breastfeeding before starting Trajenta 5 mg Tablet . Prolonged intake of Trajenta 5 mg Tablet may cause acute pancreatitis (swollen pancreas) and critical kidney problems. Increased risk of hypoglycaemia (low blood sugar level) can occur when Trajenta 5 mg Tablet is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Trajenta 5 mg Tablet . Severe allergic reactions might occur in some patients taking Trajenta 5 mg Tablet , like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions, including Stevens-Johnson syndrome. Safety and efficacy of Trajenta 5 mg Tablet in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Trajenta 5 mg Tablet should be closely monitored as severe drug interaction has been observed. Trajenta 5 mg Tablet should not be used in patients with type 1 diabetes and for the treatment of diabetic ketoacidosis.

Drug-Drug Interactions

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LinagliptinGatifloxacin
Critical
LinagliptinDobutamine
Severe

Drug-Drug Interactions

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LinagliptinGatifloxacin
Critical
How does the drug interact with Trajenta 5 mg Tablet:
Co-administration of Trajenta 5 mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Trajenta 5 mg Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without a doctor's advice.
LinagliptinDobutamine
Severe
How does the drug interact with Trajenta 5 mg Tablet:
Co-administration of Dobutamine and Trajenta 5 mg Tablet may interfere with blood glucose control and reduce the effectiveness of Trajenta 5 mg Tablet.

How to manage the interaction:
Co-administration of Trajenta 5 mg Tablet with Dobutamine can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
LinagliptinBexarotene
Severe
How does the drug interact with Trajenta 5 mg Tablet:
Taking Trajenta 5 mg Tablet with bexarotene may increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Although there is a possible interaction, Trajenta 5 mg Tablet can be taken with bexarotene if prescribed by the doctor. Contact the doctor if you experience symptoms of pancreatitis such as abdominal tenderness, persistent nausea, vomiting, and upper abdominal pain, especially if it radiates to the back or worsens after eating. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.
  • Eat at regular intervals. Do not take a long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are lots of fluctuations.
  • Invest at least 150 min of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates containing whole-grain foods and increase the intake of fruits and veggies and other fiber-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. You can use palm oil, mustard oil, groundnut oil, rice bran oil and safflower oil for frying.
  • Do not take stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yogurt, fat-free milk, and cheese, etc.).
  • Keep your blood pressure as normal (140/90) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

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Alcohol

Unsafe

Alcohol should not be consumed along with Trajenta 5 mg Tablet as it is known to interact and lead to unpleasant side effects.

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Pregnancy

Caution

Trajenta 5 mg Tablet is a category B pregnancy medication. So, its safety in pregnant women is not established. So, it should be taken only if prescribed by a doctor.

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Breast Feeding

Caution

It is not known whether Trajenta 5 mg Tablet passes through the breast milk or not. So, it should be taken only if prescribed by a doctor.

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Driving

Caution

Trajenta 5 mg Tablet has no influence on the ability to drive and use machines. However, dizziness and drowsiness have been reported, which may affect your ability to drive or use machines.

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Liver

Caution

If u have or had a history or evidence of any liver-related diseases, please consult the doctor before taking medicine.

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Kidney

Caution

If u have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking medicine.

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Children

Unsafe

Trajenta 5 mg Tablet is not recommended for children below the age of 18 years.

Have a query?

FAQs

Trajenta 5 mg Tablet is used to treat type 2 diabetes in adults along with diet and lifestyle changes. It is used alone or in combination with other drugs to lower blood sugar levels.

Trajenta 5 mg Tablet contains Linagliptin, which belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors used Trajenta 5 mg Tablet is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It works by blocking the action of DPP-4 (an enzyme that destroys the hormone ‘Incretin’). The enzyme ‘Incretins’ helps produce more insulin only when required and reduces the liver's blood sugar level when not needed. Trajenta 5 mg Tablet should not be used in patients with type 1 diabetes and for the treatment of diabetic ketoacidosis.

Type 2 diabetes is a common form of diabetes. The body cannot make a sufficient amount of insulin and the body's insulin does not function properly. The blood glucose level increases, and symptoms such as frequent urination, increased thirst, and increased hunger . Diabetes, if left untreated or not treated properly, can cause long-term complications like nerve damage, kidney damage, eye damage, foot problems, and fall under a higher risk of developing heart diseases.

Hypoglycemia refers to low blood sugar levels. Trajenta 5 mg Tablet can cause hypoglycemia. The symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness. Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. People with diabetes are advised to keep a quick sugar source like glucose tablets, honey or fruit juice.

Trajenta 5 mg Tablet should be avoided in patients who are allergic to any of this medicine's components or excipients. It should be avoided in patients suffering from moderate to severe kidney disease and in patients with underlying metabolic acidosis, including diabetic ketoacidosis, consult your doctor for further advice.

No. Trajenta 5 mg Tablet is only prescribed to treat type 2 diabetes, also called 'non-insulin-dependent diabetes.'

In type 1 diabetes, cells in the pancreas that make insulin are destroyed, and the body is unable to make insulin. Insulin is a hormone that helps your body's cells use glucose for energy. The condition is usually diagnosed in children and young people, so it used to be called juvenile diabetes.

No, Trajenta 5 mg Tablet is not the same as metformin. Both are used to treat type-2 diabetes but their mechanism of action are different. Metformin improves insulin response and reduces liver sugar production. Whereas, Trajenta 5 mg Tablet blocks DPP-4, increasing insulin production and lowering liver sugar.

Trajenta 5 mg Tablet can be taken in the morning or in the evening once a day with or without food as advised by your doctor. It is best to take it at the same time every day to maintain consistency.

The most common side effects of Trajenta 5 mg Tablet in some individuals are hypoglycemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold), and headache. Most of these side effects may not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult the doctor.

Take Trajenta 5 mg Tablet once daily, with or without food, at any time. It's best to take it at the same time each day to maintain a consistent level of the medication in your body.

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double the dose.

Trajenta 5 mg Tablet is used with caution in patients with kidney impairment. Excessive use of Trajenta 5 mg Tablet may cause kidney problems.

Yes, Trajenta 5 mg Tablet is safe to take for a long time, as it is commonly prescribed for a long-term treatment for type 2 diabetes, helping to keep blood sugar levels stable and prevent complications.

Trajenta 5 mg Tablet is taken as a long-term treatment for type 2 diabetes, and you may need to take it for as long as you have type 2 diabetes, usually for several years or even lifelong. It's essential to follow your doctor's instructions and attend regular follow-up appointments to monitor your condition and adjust your treatment plan as needed.

Stopping Trajenta 5 mg Tablet abruptly can increase blood sugar levels, harming your health. If you're considering stopping Trajenta 5 mg Tablet , it's essential to consult your doctor first. They will assess your condition, discuss alternative treatment options, and help you make an informed decision to ensure your blood sugar levels remain controlled.

Country of origin

United States

Manufacturer/Marketer address

1102, Hallmark Business Plaza, 11th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
Other Info - TRA0490

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