What is the use of Tresiba 100U/ml Penfil Injection 3 ml ?

Tresiba 100U/ml Penfil Injection 3 ml is used for the treatment of type 1 and typeÃ‚ 2 diabetes mellitus in both children (above 1 year of age) and adults.

What should I follow while taking Tresiba 100U/ml Penfil Injection 3 ml ?

Tresiba 100U/ml Penfil Injection 3 ml is only a part of a complete diabetes control program that includes regular blood sugar testing, diet, exercise, weight control, and special medical care. So follow all the instructions given by the doctor.

Can I continue my other diabetes medicines with Tresiba 100U/ml Penfil Injection 3 ml ?

It is advised to tell all the medicines that you are using like pioglitazone or rosiglitazone as taking other diabetes medicines may increase the risk of serious heart problems.

In how much time does Tresiba 100U/ml Penfil Injection 3 ml shows its effect?

Tresiba 100U/ml Penfil Injection 3 ml typically begins working after 60 minutes and will last for more than 24 hours.

Is Tresiba 100U/ml Penfil Injection 3 ml safe to use in every diabetic patient?

Tresiba 100U/ml Penfil Injection 3 ml can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Tresiba 100U/ml Penfil Injection 3 ml can be given to you or not depending on your present condition. Tresiba 100U/ml Penfil Injection 3 ml should be avoided in patients who are allergic to Tresiba 100U/ml Penfil Injection 3 ml or other forms of insulin, patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycemia), and low potassium level (hypokalaemia).

Can I drink alcohol with Tresiba 100U/ml Penfil Injection 3 ml ?

Try to avoid intake of alcoholic beverages with Tresiba 100U/ml Penfil Injection 3 ml as it may increase or decrease your blood sugar level.

What are the common signs of hypoglycaemia?

Cold sweat; cool pale skin; headache; rapid heartbeat; feeling sick; feeling very hungry; temporary vision changes; drowsiness; unusual tiredness and weakness; nervousness or tremor; feeling anxious; feeling confused; difficulty in concentrating are some of the common signs of the low blood sugar level in an individual.

What to do in case I experience low blood sugar?

If you experience low blood sugar, eat glucose tablets, or another high sugar snack (e.g. sweets, biscuits, fruit juice). Measure your blood sugar if possible and rest. Always carry glucose tablets or high sugar snacks with you. You should give a call to any of your family members if you are feeling dizziness or drowsiness.

What are the signs of allergy/rash with Tresiba 100U/ml Penfil Injection 3 ml ?

Local allergic reactions (pain, redness, hives, inflammation, bruising, swelling, and itching) at the injection site may occur. These usually disappear after a few weeks of taking your insulin. If they do not disappear, or if they spread throughout your body, talk to your doctor immediately.

How should I inject Tresiba 100U/ml Penfil Injection 3 ml ?

You can inject Tresiba 100U/ml Penfil Injection 3 ml in your upper arm, thigh, or stomach area. Do not inject Tresiba 100U/ml Penfil Injection 3 ml into your vein or muscle. Try to change (rotate) the injection site with each dose to avoid skin irritation in the same injection site.

For how many days can I use Tresiba 100U/ml Penfil Injection 3 ml ?

If you have opened the insulin pen once, it must be stored at room temperature (25-degree Celsius) and may be used for up to 56 days after its first use.

What food items I should avoid, as I'm a diabetic?

Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.

Can I stop taking Tresiba 100U/ml Penfil Injection 3 ml if I am feeling uncomfortable after taking this medicine?

Tresiba 100U/ml Penfil Injection 3 ml should not be discontinued without a doctor's consultation as stopping Tresiba 100U/ml Penfil Injection 3 ml may cause severe hypoglycaemia (low blood sugar) and ketoacidosis (buildup of acid in the blood). Consult the doctor if you feel uncomfortable after taking Tresiba 100U/ml Penfil Injection 3 ml .

Why should I always change the site for taking this injection?

The injection site should be changed to prevent skin changes like lumps under the skin. Tresiba 100U/ml Penfil Injection 3 ml may not work well if injected into the lumpy area.

What other lifestyle modifications do I need to consider to manage diabetes?

Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.

I develop low blood sugar levels often, what could be the possible reasons?

Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.

What is Tresiba 100U/ml Penfil Injection 3 ml ?

Tresiba 100U/ml Penfil Injection 3 ml is a long-acting human insulin analogue produced by rDNA process in Saccharomyces cerevisiae followed by chemical modification.

Are Insulin glargine and Tresiba 100U/ml Penfil Injection 3 ml the same?

No, insulin glargine and Tresiba 100U/ml Penfil Injection 3 ml are not the same. Tresiba 100U/ml Penfil Injection 3 ml contains insulin degludec which has a longer half-life compared to insulin glargine. Insulin degludec and insulin glargine provide similar glycemic control, but insulin degludec also lowers the risk of low blood sugar.

Is Tresiba 100U/ml Penfil Injection 3 ml better than insulin detemir?

Tresiba 100U/ml Penfil Injection 3 ml contains insulin degludec. Insulin degludec and insulin detemir were found to be equally effective in managing blood sugar levels.

What should I avoid while taking Tresiba 100U/ml Penfil Injection 3 ml ?

Avoid sharing Tresiba 100U/ml Penfil Injection 3 ml , insulin syringe or needle with other patients. Do not miss meals and regularly monitor blood sugar levels. Avoid driving or operating machinery until you know how this medicine affects you. Do not consume alcohol or use prescription or over-the-counter medicines that contain alcohol.

Can Tresiba 100U/ml Penfil Injection 3 ml be used alone?

Yes, Tresiba 100U/ml Penfil Injection 3 ml can be used alone to treat diabetes. However, Tresiba 100U/ml Penfil Injection 3 ml can be used with other diabetic medicines if prescribed by the doctor.

Is Tresiba 100U/ml Penfil Injection 3 ml basal insulin?

Yes, Tresiba 100U/ml Penfil Injection 3 ml is a long-acting basal human insulin analogue that is used to improve glycaemic control in patients with diabetes mellitus.

Can Tresiba 100U/ml Penfil Injection 3 ml cause weight gain?

Yes, Tresiba 100U/ml Penfil Injection 3 ml can cause weight gain due to the anabolic effects of insulin. Eating healthy food and exercising regularly may help manage weight gain.

Can Tresiba 100U/ml Penfil Injection 3 ml raise your blood sugar?

Tresiba 100U/ml Penfil Injection 3 ml does not raise blood sugar. However, hyperglycaemia has been reported with repeated insulin injections into areas of localised cutaneous amyloidosis (clumps of abnormal proteins called amyloids build up in the skin). Also, changes in insulin regimen may cause high/low blood sugar levels.

What are the side effects of Tresiba 100U/ml Penfil Injection 3 ml ?

Side effects of Tresiba 100U/ml Penfil Injection 3 ml include hypoglycaemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itching skin) which may occur at the injection site. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Tresiba 100U/ml Penfil Injection 3 ml

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Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tresiba 100U/ml Penfil Injection 3 ml is used for the treatment of type 1 and type 2 diabetes mellitus in both children (above 1 year of age) and adults. It contain Insulin degludec, which is a fast-acting insulin that works rapidly to normalize blood sugar levels by helping the sugar move from the blood into other tissues of the body. It prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver. It may cause common side effects such as hypokalaemia (low potassium), hypoglycemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itch skin) which may occur at the injection site.

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About Tresiba 100U/ml Penfil Injection 3 ml

Tresiba 100U/ml Penfil Injection 3 ml used for the treatment of both type 1 and type 2 diabetes mellitus. In Type 1 Diabetes Mellitus, the body does not produce enough insulin to regulate blood sugar levels. In type 2 diabetes mellitus, either the body stops producing enough insulin (a hormone that helps lower blood sugar levels) or there is resistance to the action of insulin. As a result, insulin is produced in large quantities, but it is unable to function correctly in the body's organs.

Tresiba 100U/ml Penfil Injection 3 ml contains insulin degludec, which helps normalise blood sugar levels by facilitating the movement of sugar from the blood into other tissues of the body. It reduces the risk of severe diabetes complications. It stimulates the recovery of sugar in muscle and fat cells, thereby suppressing the production of sugar in the liver.

Not everyone who is taking Tresiba 100U/ml Penfil Injection 3 ml will get these side effects. You may experience rash, injection site allergic reaction, weight gain, edema (tissue swelling or fluid overload), skin thickening at the injection site, low blood glucose levels, and itching. Most of these side effects of Tresiba 100U/ml Penfil Injection 3 ml do not require medical attention and typically resolve on their own over time. However, if the side effects are persistent, reach out to your doctor.

Tresiba 100U/ml Penfil Injection 3 ml should be taken before food or advised by your doctor. It should be administered subcutaneously (in the upper thigh, abdomen, upper arm, or buttocks) only. Your doctor will explain how to administer the medicine yourself. However, if it is difficult to inject the medicine, ask a healthcare professional to take it. Along with Tresiba 100U/ml Penfil Injection 3 ml , you should maintain a healthy diet, engage in regular exercise, and adhere to your doctor's weight management advice.

Inform your doctor if you are allergic to Tresiba 100U/ml Penfil Injection 3 ml . Do not take Tresiba 100U/ml Penfil Injection 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription or recreational drugs. Try not to stop receiving Tresiba 100U/ml Penfil Injection 3 ml of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Tresiba 100U/ml Penfil Injection 3 ml is a cold chain medicine, and so it must be stored in the refrigerator between 2-8 degrees Celsius, or else its efficiency might get lost. Do not store in the freezer or the fridge.

Uses of Tresiba 100U/ml Penfil Injection 3 ml

Tresiba 100U/ml Penfil Injection 3 ml is used in the treatment of Diabetes (type 1 diabetes mellitus and type 2 diabetes mellitus). The detailed uses of Tresiba 100U/ml Penfil Injection 3 ml are as follows:
• Diabetes Management: Tresiba 100U/ml Penfil Injection 3 ml is primarily used to regulate blood glucose levels in individuals with diabetes mellitus, helping to keep them within a healthy range.
• Postprandial Blood Sugar Control: Tresiba 100U/ml Penfil Injection 3 ml effectively manages postprandial (after-meal) blood sugar spikes through its combination of intermediate and short-acting insulin.
• Type 1 and Type 2 Diabetes Treatment: Tresiba 100U/ml Penfil Injection 3 ml is prescribed for patients with Type 1 and Type 2 diabetes who are unable to achieve adequate glycemic control with oral hypoglycemic agents alone.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety. • Administer Tresiba 100U/ml Penfil Injection 3 ml subcutaneously as instructed by the doctor. Your doctor will train you on how to use Tresiba 100U/ml Penfil Injection 3 ml at home. Check the label for directions and use it as advised by the doctor. Tresiba 100U/ml Penfil Injection 3 ml should be administered subcutaneously (under the skin) in the thighs, abdomen, buttocks, or upper arm. • Rotate the injection site each time. Do not inject into the areas where the skin is tender, red, bruised, hard, scarred or has stretch marks.

Medicinal Benefits

Tresiba 100U/ml Penfil Injection 3 ml is an antidiabetic medicine primarily used for the treatment of both type 1 and type 2 diabetes mellitus.
It prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells, thereby suppressing sugar production in the liver.
Tresiba 100U/ml Penfil Injection 3 ml helps improve glycaemic control, which in turn decreases the risk of complications of diabetes, such as damage to the retina (retinopathy), damage to the kidneys (nephropathy), impairment of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcers, and others.
Tresiba 100U/ml Penfil Injection 3 ml can also be safely prescribed to the diabetic mother during pregnancy and lactation.
It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver.

How Tresiba 100U/ml Penfil Injection 3 ml Works

Tresiba 100U/ml Penfil Injection 3 ml contains insulin degludec which is a fast-acting insulin that works rapidly to normalize blood sugar levels by helping the sugar move from the blood into other tissues of the body.

Storage

Store in a cool and dry place away from sunlight

Side effects of Tresiba 100U/ml Penfil Injection 3 ml

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Inflammation Of Sinuses

Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):

Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.

Stomach Flu

Get ample rest; this helps your stomach to settle.
Eat soft and easy-to-digest foods like white rice, bananas, crackers and apple sauce.
Include probiotics-rich food like yoghurt, kefir, or miso, as they help maintain gut functioning.
Wash your hands properly before preparing/eating food and after using the toilet.
Drink water, broth or diluted fruit juice to replace electrolytes and lost fluids.
Avoid caffeine, alcohol, high-fat, fried and fast foods, as well as sweetened beverages.

Injection Site Reaction

Injection site reaction can include numbness or redness.
Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
Apply cold compress for pain relief.
Practice good hygiene and keep the injection site away from heat and pressure.

Swelling In The Feet And Ankles

Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
Gently massage the swollen area with firm but not painful pressure.
Keep the swollen area clean and moisturized to prevent injury and infection.
Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.

Common Cold

Here are the steps to manage the medication-triggered Common Cold:

Inform your doctor about the common cold symptoms you're experiencing due to medication.
Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Low Blood Sugar

If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
Make medication adjustments as recommended by your doctor to prevent future episodes.
Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
Monitor your blood sugar levels closely for patterns and changes.
Track your progress by recording your blood sugar levels, food intake, and physical activity.
Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.

What if I have taken an overdose of Tresiba 100U/ml Penfil Injection 3 ml

Do not use more than the prescribed dose of Tresiba 100U/ml Penfil Injection 3 ml as it may cause overdose. The symptoms of overdose include hypoglycemia (low blood sugar), seizures (fits) or loss of consciousness. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor if you are allergic to Tresiba 100U/ml Penfil Injection 3 ml . Do not take Tresiba 100U/ml Penfil Injection 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription or recreational drugs.
Try not to stop receiving Tresiba 100U/ml Penfil Injection 3 ml of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Tresiba 100U/ml Penfil Injection 3 ml may decrease the level of potassium, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma, and even death.
Tresiba 100U/ml Penfil Injection 3 ml is for subcutaneous (under the skin) use only. If you are switching to a different insulin brand or using a different method of injection, it should be done under strict medical supervision.
Cases of heart failure have been reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure.
The first symptoms of hyperglycemia (high blood sugar levels) may include excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite, and an acetone odour in the breath. You should closely monitor these symptoms.
It is advisable not to consume alcohol, as it may either increase or decrease your blood glucose level.
Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule.
Tresiba 100U/ml Penfil Injection 3 ml is a cold chain medicine, and therefore it must be stored in the refrigerator at a temperature between 2-8 degrees Celsius, or else its efficiency may be compromised. Do not store in the freezer or the fridge.
Keep the medicine out of reach of children. Please do not inject more than the recommended dose of medicine, as it can cause undesirable effects.
It is always important to check the expiry date of the medicine. Discard the medicine if it reaches the expiry date.

Drug-Drug Interactions

Insulin degludecGemifloxacin

Severe

Insulin degludecGrepafloxacin

Severe

Drug-Drug Interactions

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Insulin degludecGemifloxacin

Severe

How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with Gemifloxacin affects blood glucose levels, which may cause hyperglycaemia (high blood glucose) and hypoglycaemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and Gemifloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycaemia or hyperglycaemia. Symptoms of hypoglycaemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycaemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Insulin degludecGrepafloxacin

Severe

How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with grepafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and grepafloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Insulin degludecNorfloxacin

Severe

How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with norfloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and norfloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Insulin degludecCiprofloxacin

Severe

How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with ciprofloxacin can effect blood sugar levels, both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and Ciprofloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, excessive sweating, and rapid heartbeat, increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Insulin degludecCinoxacin

Severe

How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with cinoxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and Cinoxacin, it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Insulin degludecTrovafloxacin

Severe

How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with trovafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and trovafloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Insulin degludecEnoxacin

Severe

How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with Enoxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia(low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and cinoxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Insulin degludecGatifloxacin

Severe

How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with Gatifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia less frequently.

How to manage the interaction:
There could be a possible interaction between insulin aspart and Gatifloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Insulin degludecLevofloxacin

Severe

How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Coadministration of levofloxacin and Tresiba 100U/ml Penfil Injection 3 ml can sometimes affect blood glucose levels - Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose).

How to manage the interaction:
Although using levofloxacin and Tresiba 100U/ml Penfil Injection 3 ml at the same time may cause an interaction, they can be taken together if a doctor has prescribed it. Inform doctor if you develop hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose), or if you have trouble controlling your blood glucose. Hypoglycemia symptoms include headache, dizziness, tiredness, anxiety, disorientation, a shaking sensation, nausea, hunger, weakness, sweating, palpitation, and a rapid pulse. Hyperglycemia symptoms include Increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Insulin degludecOfloxacin

Severe

How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with ofloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and ofloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Exercise may lower your body’s need for insulin during and for some time after the physical activity.
Exercise may also speed up the effect of an insulin dose, especially if the exercise involves the area of the injection site (for example, the leg should not be used for injection just prior to running).
Discuss with your doctor how you should adjust your insulin regimen to accommodate exercise.
Avoid eating sugar food and prefer food cooked food low in calories.
When traveling across more than 2 time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Alcohol

Unsafe

You are recommended not to consume alcohol along with Tresiba 100U/ml Penfil Injection 3 ml to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

Pregnancy

Safe if prescribed

Tresiba 100U/ml Penfil Injection 3 ml can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery.

Breast Feeding

Safe if prescribed

Tresiba 100U/ml Penfil Injection 3 ml can be given safely to nursing mothers but only under the supervision of a physician.

Driving

Unsafe

Drive with caution, Tresiba 100U/ml Penfil Injection 3 ml usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycaemia (low blood sugar).

Liver

Caution

Tresiba 100U/ml Penfil Injection 3 ml to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

Kidney

Caution

Tresiba 100U/ml Penfil Injection 3 ml to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.