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  3. Trezam 1G Injection

Trezam 1G Injection, Pack of 1
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Trezam 1G Injection is used to treat bacterial infections. It contains Aztreonam which works by killing the infection-causing bacteria. In some cases, this medicine may cause side effects such as dizziness, headache, sneezing, high temperature, and double vision. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

AZTREONAM-1000Mg

Manufacturer/Marketer :

Glenmark Pharmaceutical Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Trezam 1G Injection

Trezam 1G Injection belongs to a class of antibiotics used in the treatment of serious bacterial infections. A bacterial infection is a condition in which harmful bacteria grows in the body and causes infection. It can infect any part of the body and multiple very quickly.

Trezam 1G Injection contains aztreonam, which belongs to a class of monobactam antibiotics. It works by inhibiting the formation of the bacterial cell wall (a protective covering) that is necessary for their survival.

Some common side effects of Trezam 1G Injection include dizziness, bad breath, headache, sneezing, high temperature, bleeding of the stomach, double vision. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you are known to be allergic to Trezam 1G Injection or any other medicines, please tell your doctor. Do not receive Trezam 1G Injection if you are pregnant or breastfeeding. Consult your doctor immediately if you notice signs of allergic reaction such as swelling of the face, lips, throat, and/or tongue with difficulty in breathing after receiving Trezam 1G Injection.

Uses of Trezam 1G Injection

Treatment of Bacterial infections

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Trezam 1G Injection will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Trezam 1G Injection belongs to the class of monobactam antibiotics. It reduces the infection by inhibiting bacterial growth. It kills the bacteria by disrupting the formation of the cell wall. It irreversibly binds to the proteins in the bacteria that are essential for the formation of the cell membrane.

How Trezam 1G Injection Works

Trezam 1G Injection contains aztreonam, which belongs to a class of monobactam antibiotics. It works by inhibiting the formation of the bacterial cell wall (a protective covering) that is necessary for their survival.

Storage

Keep Trezam 1G Injection out of the sight and reach of children.
Side effects of Trezam 1g Inj
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.
  • Stay hydrated by drinking plenty of water to help reduce swelling.
  • Include anti-inflammatory foods like turmeric, ginger, and omega-3 rich foods in your diet.
  • Avoid processed and high-sodium foods that can exacerbate swelling.
  • Utilize an ice pack wrapped in a cloth to cool the affected area, helping to alleviate swelling and discomfort.
  • Gently massage the site, if recommended by your healthcare provider, to promote lymphatic drainage.
  • Rotate injection sites to minimize irritation and swelling.
  • Allow your body time to rest and recuperate, limiting physically demanding tasks to facilitate a smoother recovery.

What if I have taken an overdose of Trezam 1G Injection

It is unlikely to overdose on parenteral medication as it is administered by a healthcare professional. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Regular monitoring of kidney and liver functioning is recommended while taking Trezam 1G Injection. If you are a breastfeeding or pregnant woman, please consult a doctor before taking Trezam 1G Injection. If you notice blood in stools or have severe stomach pain with diarrhoea, contact your doctor immediately. Inform your doctor before taking Trezam 1G Injection if you have liver problems, kidney problems, blood disorders, fits. Also, inform your doctor if you are already taking medicines like antibiotics or oral anticoagulants. 

Drug-Drug Interactions

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AztreonamBCG vaccine
Severe
AztreonamCholera, live attenuated
Severe

Drug-Drug Interactions

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AztreonamBCG vaccine
Severe
How does the drug interact with Trezam 1g Inj:
When BCG vaccine is used together with Trezam 1g Inj, its effectiveness may be reduced.

How to manage the interaction:
There may be a possibility of interaction between Trezam 1g Inj and BCG vaccine, but it can be taken if prescribed by a doctor. Do not stop using any medications without first talking to your doctor.
AztreonamCholera, live attenuated
Severe
How does the drug interact with Trezam 1g Inj:
Coadministration of Trezam 1g Inj with Cholera vaccine can reduce the effects of Cholera vaccine.

How to manage the interaction:
Taking Trezam 1g Inj with Cholera vaccine together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Trezam 1G Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can help to restore the good bacteria of the intestine.
  • Include fibre rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread, brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Trezam 1G Injection.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Trezam 1G Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

The interaction of alcohol with Trezam 1G Injection is unknown. Please consult a doctor before consuming alcohol while using Trezam 1G Injection.

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Pregnancy

Caution

The safety of Trezam 1G Injection in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Trezam 1G Injection is excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Caution

Trezam 1G Injection cause double vision, dizziness as a side effect. So, avoid driving after receiving Trezam 1G Injection.

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Liver

Caution

Take Trezam 1G Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Trezam 1G Injection with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Trezam 1G Injection can be given safely to children, dose to be adjusted and recommended by a child specialist only.

Have a query?

FAQs

Trezam 1G Injection contains Aztreonam, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria.

No. You should complete the full course of Trezam 1G Injection as prescribed by your doctor. After completing the full course of Trezam 1G Injection will work. It is important that you take Trezam 1G Injection at the right dose, right times, and for the right numbers of days.

Trezam 1G Injection does not work against viral infection. So, it should not be taken to treat common cold cough and cough

Trezam 1G Injection may cause dizziness and double vision. So, drive only if you are alert and avoid driving and operating machinery if you feel dizzy or experience vision changes.

Trezam 1G Injection is used in the treatment of serious bacterial infections that require injectable antibiotics. Trezam 1G Injection targets infections across different areas of the body and may be used in combination with other antibiotics when necessary.

Trezam 1G Injection will be administered by a healthcare professional in a hospital or clinic setting. Trezam 1G Injection will either be given directly into your vein (IV) or as an infusion. Alternatively, Trezam 1G Injection can also be injected into a large muscle, such as the buttocks or thigh, depending on your condition and a physician's recommendation. The method of administration will be determined by your doctor to ensure the correct dosage and effectiveness.

Trezam 1G Injection may be safe for patients who are allergic to penicillin as Trezam 1G Injection is a monobactam antibiotic, which is chemically different from penicillins and has shown no significant cross-reactivity in patients with penicillin allergies. However, as with any medication, it is important to inform your doctor about any known allergies before use to ensure safety.

Trezam 1G Injection causes side effects such as dizziness, chest pain, headache, double vision, bad breath, vaginal irritation, and a blocked nose. However, please contact a doctor if these side effects worsen or persist longer.

Country of origin

India
Other Info - TRE0439

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:51 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.3773.pdf
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