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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

TRIHEXIPHENIDYL-2MG

Manufacturer/Marketer :

Hellix Healthcare

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Trimelin 2mg Tablet

Trimelin 2mg Tablet is an oral prescription medication used to manage symptoms of Parkinson’s disease and involuntary movement control disorders caused by certain medications. It helps reduce muscle stiffness, severe shaking, and sudden muscle spasms. By restoring the natural balance of specific chemical messengers in the brain, it supports smoother, more controlled physical movements.

To achieve the best results, take this medicine consistently at the same time every day as directed by your healthcare provider. This medication can be taken with or without food, though taking it with meals can help reduce stomach upset if you experience nausea. Incorporating a fibre-rich diet and staying well-hydrated are also highly beneficial lifestyle changes to support your digestive health during treatment.

While using this medicine, you may experience mild side effects like a dry mouth, mild dizziness, or blurred vision. However, you must seek immediate medical attention if you experience severe symptoms such as eye pain, severe confusion, or difficulty urinating. Always consult your doctor if you experience any bothersome or persistent symptoms.

Talk to your doctor if you have a history of heart disease, high blood pressure, kidney or liver conditions, or prostate problems. Do not take this medicine if you have narrow-angle glaucoma, severe bowel blockages, or difficulty urinating. Your doctor will evaluate your medical history to ensure this treatment is safe for you.

Avoid drinking alcohol while taking this medicine because it can severely increase drowsiness and dizziness. Tell your doctor about all other medicines you take, as combining this treatment with sedatives, antihistamines, or other nervous system drugs can cause intense side effects. If you are pregnant, planning to breastfeed, or are an older adult, consult your doctor or pharmacist to discuss your specific risks.

Uses of Trimelin 2mg Tablet

Trimelin 2mg Tablet is used in the treatment of Parkinson’s disease. The detailed uses of Trimelin 2mg Tablet are as follows:

  • Treats Parkinson’s symptoms: Trimelin 2mg Tablet helps control muscle stiffness, severe shaking (tremors), and sudden muscle spasms, allowing for smoother physical coordination.
  • Controls drug-induced movement problems: Trimelin 2mg Tablet relieves involuntary muscle movements, severe restlessness, and muscle rigidity caused by taking certain psychiatric medications.
  • Improves muscle control: By balancing certain brain chemicals, Trimelin 2mg Tablet improves coordination and reduces abnormal muscle movements.

Key Benefits

Trimelin 2mg Tablet helps control muscle stiffness, severe shaking (tremors), and sudden muscle spasms, allowing for smoother physical coordination.

Benefits may include:

  • This medicine allows you to perform daily tasks like eating, writing, and dressing with greater ease and independence.
  • It relaxes tense, rigid muscles, helping you move more comfortably and freely throughout the day.
  • It targets and calms the distressing restlessness or involuntary muscle spasms that can occur as a side effect of other necessary medications.
Side effects of Trimelin 2mg Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Frequent flossing and brushing can help remove bacteria and debris that can give your teeth a metallic taste.
  • The metallic flavor may be caused by a zinc deficiency. Eat foods like meat, chicken, and oysters that are high in zinc.
  • Reducing the intake of foods with strong aromas, like onions and garlic, as they may intensify the taste of metallic substances.
  • Avoid smoking and tobacco products as they may intensify the metallic flavor.

Directions for Use

  • Take this medication exactly as prescribed by your doctor. Do not change your dose without consulting them.
  • Swallow the tablet whole with a full glass of water. Do not chew, crush, or break the tablet unless your healthcare provider instructs you to do so.
  • You may take this medicine either with or without food. Taking it with a meal can help ease a mild stomach upset.
  • Always follow your doctor's exact instructions regarding how and when to take your medication. Do not alter your routine on your own.

How Trimelin 2mg Tablet Works

Trimelin 2mg Tablet belongs to a class of medicines called anticholinergics. It works by blocking a natural chemical messenger in the body called acetylcholine, which is responsible for sending signals that make muscles contract. In conditions like Parkinson's disease, or when taking certain other medications, an imbalance occurs where there is too much acetylcholine activity relative to dopamine. This imbalance leads to involuntary movements, stiffness, and shaking. By blocking this excess acetylcholine, it restores a healthy chemical balance in your brain and nervous system. This direct action helps to relax your muscles, dampens tremors, and smooths out your overall physical movements.
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Alcohol

Unsafe

It is unsafe to consume alcohol since alcohol consumption with Trimelin 2mg Tablet may increase the risk of dizziness, fainting, or headache.

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Pregnancy

Unsafe

Trimelin 2mg Tablet is not safe in pregnancy because it causes miscarriage and abnormalities in the fetus. It is better to consult your doctor to know the risks and benefits associated with Trimelin 2mg Tablet .

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Breast Feeding

Unsafe

Trimelin 2mg Tablet is not allowed to be taken by a breastfeeding mother as it may pass into breast milk and affect the nursing baby. It is better to consult your doctor to learn the risks and benefits associated with Trimelin 2mg Tablet .

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Driving

Caution

Trimelin 2mg Tablet is not safe during the drive because it can make you feel drowsy. So, it would be best not to do anything that requires concentration and attention.

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Liver

Caution

Trimelin 2mg Tablet to be taken with caution, especially if you have a history of liver diseases. Your doctor may adjust the dose based on your medical condition.

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Kidney

Caution

Trimelin 2mg Tablet should be taken with caution, especially if you have a history of kidney diseases. Your doctor may adjust the dose based on your medical condition.

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Children

Safe if prescribed

Trimelin 2mg Tablet can only be advised to children if prescribed by a doctor.

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Heart

Caution

Trimelin 2mg Tablet is used with caution in cardiac patients and regular monitoring is required.

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Geriatrics

Not applicable

Trimelin 2mg Tablet is not recommended for use in elderly patients.

What if I have taken an overdose of Trimelin 2mg Tablet

If you suspect an overdose, seek immediate medical attention or contact a poison control centre. Symptoms of an overdose may include severe dry mouth, dilated pupils, fever, rapid heart rate, confusion, or loss of consciousness.

Diet & Lifestyle Advise

  • Manage Dry Mouth: Sip water throughout the day, suck on ice chips, or chew sugar-free gum to keep your mouth moist. Practice oral hygiene (brushing, flossing, and regular dental cleanings), as dry mouth significantly increases the risk of dental caries (tooth decay).
  • Prevent Constipation: Eat a diet high in fibre (such as whole grains, vegetables, and fruits) and drink plenty of fluids to maintain regular bowel movements.
  • Stay Cool in Hot Weather: This medicine can make you sweat less, which increases your risk of overheating. Stay indoors in air conditioning when it is very hot, avoid strenuous outdoor activities, and drink extra water.
  • Avoid Sudden Falls: Since this medication can make you dizzy, stand up slowly from a sitting or lying position to give your body time to adjust.

Have a query?

How Soon It Starts Working

  • The time required for Trimelin 2mg Tablet to start to work: The time required for Trimelin 2mg Tablet to start to work is 1 hour after administration.
  • The time for which the effects of Trimelin 2mg Tablet last: The effect of Trimelin 2mg Tablet lasts for 6 to 12 hours.

What if you forget to take Trimelin 2mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Get Regular Eye Exams: Schedule routine eye exams while taking this medication, as it can dangerously increase pressure inside your eyes.
  • Do Not Stop Suddenly: Never stop taking Trimelin 2mg Tablet abruptly, as doing so can cause your muscle stiffness and shaking to return suddenly and severely. Your doctor will help you by gradually decreasing your dose if you need to stop.
  • Be Careful with Tasks: Do not drive, operate heavy machinery, or perform tasks requiring clear vision until you know how this medicine affects your coordination and alertness. Limit Alcohol: Avoid drinking alcohol while using this medicine, as it can worsen drowsiness and coordination problems.
  • Watch for Heat Stroke: Monitor yourself for signs of overheating, such as a high body temperature, red or dry skin, or a rapid pulse during physical activity.
  • Pregnancy & Breastfeeding: This medicine is not recommended during pregnancy and breastfeeding as it may affect the baby.

Drug-Drug Interactions

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Drug-Drug Interactions:

  • Anticholinergic medicines (e.g., certain antihistamines, tricyclic antidepressants, phenothiazines): Taking these medicines alongside Trimelin 2mg Tablet may significantly increase the risk of dry mouth, constipation, blurred vision, and urinary retention.
  • Sedatives and sleep medicines (e.g., sleeping pills, muscle relaxants, anti-anxiety medicines): Combining these with Trimelin 2mg Tablet may cause excessive drowsiness, dizziness, and impaired alertness.

Drug-Food Interactions:

  • Alcohol: Avoid consuming alcohol while taking Trimelin 2mg Tablet , as it can worsen side effects such as drowsiness, dizziness, and poor coordination.

Drug-Disease Interactions:

  • Narrow-angle glaucoma: Trimelin 2mg Tablet may increase pressure inside the eye and worsen symptoms in people with narrow-angle glaucoma.
  • Urinary blockage (e.g., bladder outlet obstruction): This medicine may worsen urinary retention and should generally be avoided in patients with urinary blockages.
  • Severe bowel obstruction: Trimelin 2mg Tablet may reduce bowel movement and worsen existing intestinal blockages.
  • Enlarged prostate (e.g., benign prostatic hyperplasia): This medicine may increase difficulty in passing urine and require careful monitoring.
  • High blood pressure: Patients with high blood pressure should use Trimelin 2mg Tablet cautiously, as it may affect cardiovascular function.
  • Heart disease: Trimelin 2mg Tablet may worsen certain heart conditions and may require closer monitoring during treatment.
  • Liver disease: Reduced liver function may affect how Trimelin 2mg Tablet is processed in the body, increasing the risk of side effects.
  • Kidney disease: Patients with kidney impairment may require careful monitoring, as the medicine may remain in the body for longer periods.

Drug-Drug Interactions

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How does the drug interact with Trimelin 2mg Tablet:
Co-administration of Metformin and Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Metformin with Metrizamide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, nausea, vomiting, diarrhea, muscle cramps or pain, body weakness, extreme fatigue, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trimelin 2mg Tablet:
Taking Glimepiride with Gatifloxacin may cause both low blood glucose and, less frequently, high blood glucose.

How to manage the interaction:
Gatifloxacin is not recommended for patients with diabetes, however, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Trimelin 2mg Tablet:
Co-administration of Iopamidol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iopamidol is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Trimelin 2mg Tablet:
Co-administration of Iodixanol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iodixanol is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Trimelin 2mg Tablet:
Co-administration of Iopromide with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Iopromide with Metformin is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Trimelin 2mg Tablet:
Co-administration of Iomeprol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iomeprol is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Trimelin 2mg Tablet:
Co-administration of Metformin and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Metformin with Iodamide is generally avoided as it can result in an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Trimelin 2mg Tablet:
Co-administration of Metformin with Methazolamide may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Metformin and Methazolamide, you can take these medicines together if prescribed by a doctor. However, if you have symptoms such as weakness, muscle pain, respiratory distress, fatigue, loss of appetite, slow or irregular heartbeat, breathing difficulty, or chills, contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Trimelin 2mg Tablet:
Co-administration of Glimepiride with Voriconazole may increase the blood levels and effects of Glimepiride and may lead to hypoglycemia - low blood glucose.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with voriconazole if prescribed by the doctor. Consult a prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremors, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Trimelin 2mg Tablet:
Taking ciprofloxacin with glimepiride can cause both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).

How to manage the interaction:
Although taking ciprofloxacin and glimepiride together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, excessive sweating, and rapid heartbeat or increased thirst, increased hunger, and increased urination. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPARKINSON AGENTS]

FAQs

Trimelin 2mg Tablet belongs to the class of medications called antiparkinson agents, indicated in the treatment of Parkinson's disease.

Avoid doing exercise in hot weather as it can make you overheated or dehydrated. Trimelin 2mg Tablet can reduce sweating and increase the risk of heatstroke.

Tell your doctor if you are dealing with medical conditions like glaucoma, an enlarged prostate, urination problems, a bowel obstruction, severe constipation, epilepsy or other seizure disorders, heart problems, coronary artery disease (clogged arteries), high blood pressure, alcoholism, a problem with your nerves, brain, or spinal cord. After checking your health condition, the doctor will decide if Trimelin 2mg Tablet is safe for you or not.

It has been reported that Trimelin 2mg Tablet is not suitable for patients with narrow-angle glaucoma (damage to the optic nerve that is essential for good vision) as it may increase fluid pressure inside the eye. However, regular monitoring of eye pressure is recommended while on treatment with Trimelin 2mg Tablet . Consult a doctor for further advice.

It is advised not to stop taking Trimelin 2mg Tablet without consulting your doctor, as it may make the condition worse. Therefore, take Trimelin 2mg Tablet for as long as your doctor has prescribed it, and if you notice any improvement in your situation, please consult your doctor so that the dose may be adjusted.

Parkinson's disease is a gradually progressing, lifelong disease that is chronic and gets worse with time. With the right medicine, only the symptoms of Parkinson's disease can be managed.

Trimelin 2mg Tablet is typically taken three or four times a day, either with or without food. For best results, take it at the same time each day. However, always take Trimelin 2mg Tablet as per dose and duration advised by your doctor.

Before taking Trimelin 2mg Tablet , inform your healthcare expert if you have any heart, liver, kidney, high blood pressure, stomach, bowel, bladder, or prostate issues, or a history of tardive dyskinesia (TD). Also, mention any other medications, supplements, or herbal products you are using to avoid potential interactions. If you are pregnant or breastfeeding, discuss potential risks with your doctor.

Take Trimelin 2mg Tablet as directed by your doctor. Swallow Trimelin 2mg Tablet whole with a glass of water; do not crush, chew, or break it.

No, Trimelin 2mg Tablet is not a narcotic. It does not have any habit-forming potential. So, you may not get high after taking Trimelin 2mg Tablet . However, its ability to cause hallucinations (illusions) and feelings of euphoria (feeling of excitement) may lead some people to misuse it. Therefore, do not take Trimelin 2mg Tablet unless advised by a doctor.

Trimelin 2mg Tablet may make drowsy in some people, but it is not known how often drowsiness occurs. Avoid driving or operating heavy machinery if you feel drowsy.

If you have taken more than the recommended doses of Trimelin 2mg Tablet , seek medical help right away. Symptoms of an overdose may include dry mouth, blurred vision, and confusion. Be sure to bring the medicine bottle with you, even if it's empty.

You are not recommended to crush Trimelin 2mg Tablet as it may lose effectiveness or cause side effects when altered. Therefore, consult a doctor before taking Trimelin 2mg Tablet as they can advise you on whether it's safe to crush the tablet.

You can take Trimelin 2mg Tablet with food or without food or just after the meal as advised by your doctor at regular doses.

You are recommended to use Trimelin 2mg Tablet for as long as it is advised by your doctor for effective results. If your symptoms continue or worsen, seek further advice from your doctor.

Weight gain is not typically associated with Trimelin 2mg Tablet . However, some individuals may experience changes in appetite or other side effects. Consult your doctor, if you have any concerns.

Trimelin 2mg Tablet may cause side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, and drowsiness. However, these will reduce over time. Please consult a doctor if these side effects persists longer.

No, Trimelin 2mg Tablet does not cure Parkinson's disease. Instead, it helps manage and reduce the physical symptoms of the condition, such as muscle stiffness, tremors, and spasms, allowing you to move more comfortably. Talk to your doctor to understand how this medicine fits into your long-term treatment plan.

Yes, you can take Trimelin 2mg Tablet with or without food. If it causes stomach upset or nausea, taking it with a meal can help. However, if it causes dry mouth, taking it before meals may make swallowing food easier. Talk to your doctor or pharmacist about the best routine for you.

Dry mouth is a common effect of this medication. You can manage this by sipping water frequently, sucking on ice chips or sugar-free hard candies, and chewing sugar-free gum. Regular dental checkups are also important to protect your teeth. Talk to your doctor or pharmacist if the dry mouth becomes severe.

Yes, this medication can sometimes cause confusion, memory problems, or hallucinations, particularly in older adults. If you or a family member notice any unusual changes in your thinking, memory, or behavior, contact your healthcare provider immediately. Talk to your doctor for guidance.

Trimelin 2mg Tablet can cause blurred vision, drowsiness, and mild dizziness. It is not safe to drive, operate machinery, or perform any hazardous tasks until you know exactly how this medication affects you. Talk to your doctor if you have concerns about your safety.

The effects of Trimelin 2mg Tablet typically begin within one hour of taking your oral dose. Your physical symptoms should start to improve during this time. If you do not notice an improvement after several days, do not change your dose; instead, talk to your doctor.

Yes, this medication can decrease your body's ability to sweat, which can lead to overheating and heat stroke, especially in hot weather or during heavy exercise. Drink plenty of fluids, stay in cool environments, and avoid strenuous physical activity when it is hot. Talk to your doctor if you show signs of heat exhaustion.

Disclaimer

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Country of origin

INDIA

Manufacturer/Marketer address

Khasra No 410, Village Karondi, Roorkee-Deheradun Highway, ROORKEE 247667, Roorkee, Uttarakhand 247667
Other Info - TRI0819
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