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Tritanrix HB Injection is an immunizing medication used to prevent tetanus, diphtheria, pertussis, and hepatitis B infections in children. It works by stimulating the immune system to fight against these microorganisms, providing protection against infection. Your child may experience pain at the injection site or discomfort, redness, or swelling at the injection site, fever, drowsiness, irritability, and unusual crying.

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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DIPHTHERIA TOXOID-30IU+HEPATITIS B VACCINE-RDNA-10MCG+PERTUSSIS TOXOID-4IU+TETANUS TOXOID-60IU

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Tritanrix HB Injection

Tritanrix HB Injection is an injection used to protect infants and young children from four highly infectious diseases: diphtheria, hepatitis B, pertussis (whooping cough), and tetanus. It helps the body's immune system build protection against these infections before exposure occurs. This protection is important because these diseases can cause serious and, in some cases, long-term health complications.

This vaccine is given as a series of injections over several months according to the recommended immunisation schedule. It is injected into a muscle and does not require fasting or any special dietary preparation beforehand. Keeping your child calm and adequately hydrated during the vaccination visit can help make the experience more comfortable.

Most children experience only mild, temporary effects such as soreness or redness at the injection site, mild fever, or slight irritability. These effects usually settle on their own. However, if your child develops a severe allergic reaction, a very high fever, a seizure, or unusual unresponsiveness, seek medical attention promptly.

Do not give this vaccine if your child has previously had a severe allergic reaction to a previous dose of this vaccine or to one of its ingredients. Before vaccination, tell your doctor if your child has a bleeding disorder, a weakened immune system, or a history of seizures or other neurological conditions. A previous unexplained encephalopathy (a serious brain disorder causing reduced consciousness or other major changes in brain function) within 7 days of a pertussis-containing vaccine is a contraindication to receiving another vaccine containing pertussis.

Tell your doctor if your child is taking medicines that weaken the immune system, as these may reduce the immune response to the vaccine. Because this is primarily a childhood vaccine, alcohol and smoking interactions are not generally relevant to the child receiving it. If an adult is being considered for a vaccine containing these components under special circumstances, tell the doctor if you are pregnant, breastfeeding, or an older adult.

Uses of Tritanrix HB Injection

Your doctor may prescribe Tritanrix HB Injection to help prevent the following diseases:

  • Diphtheria prevention: Tritanrix HB Injection helps the immune system develop protection against the toxin produced by diphtheria-causing bacteria, reducing the risk of serious complications such as breathing problems and heart damage.
  • Tetanus prevention: Tritanrix HB Injection helps the immune system develop protection against tetanus, a serious infection that can enter the body through cuts or wounds and cause painful muscle stiffness and spasms.
  • Pertussis prevention: Tritanrix HB Injection helps the immune system develop protection against pertussis (whooping cough), reducing the risk of severe coughing and respiratory complications, particularly in young children.
  • Hepatitis B prevention: Tritanrix HB Injection helps the immune system produce antibodies against the hepatitis B virus, reducing the risk of long-term infection and liver damage.

Key Benefits

When used as directed as part of your child's immunisation plan, Tritanrix HB Injection may provide the following benefits:

  • Provides protection against four diseases: Tritanrix HB Injection combines protection against diphtheria, tetanus, pertussis, and hepatitis B in one vaccine series.
  • Reduces the number of separate injections: Combining several vaccine components into one injection series can reduce the number of needle sticks needed to provide protection against these diseases.
  • Helps prevent serious complications: Protection against these infections can reduce the risk of serious complications, such as severe breathing problems from diphtheria or pertussis, painful muscle spasms from tetanus, and long-term liver damage from hepatitis B.
  • Supports community protection: High vaccination coverage helps reduce the spread of vaccine-preventable infections and provides indirect protection to people who may be particularly vulnerable to severe disease.
     

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Tritanrix HB Injection will be administered by a healthcare professional.
  • Do not self-administer.

How Tritanrix HB Injection Works

Tritanrix HB Injection contains four vaccine components that teach the immune system to recognise and fight the infections they are designed to prevent. The components do not cause the diseases they are intended to prevent. Instead, they expose the immune system to safe forms or parts of the relevant bacteria, virus, or toxins so that it can develop immune memory. The diphtheria toxoid component teaches the immune system to recognise and neutralise the harmful toxin produced by diphtheria-causing bacteria. A toxoid is a toxin that has been treated so that it cannot cause the harmful effects of the original toxin but can still stimulate protective immunity. The hepatitis B vaccine component teaches the immune system to recognise hepatitis B virus proteins and produce protective antibodies. If the vaccinated person is exposed to hepatitis B virus later, the immune system can respond more quickly and help prevent infection. The pertussis toxoid component helps the immune system recognise components associated with the bacteria that cause pertussis (whooping cough). This allows the immune system to develop targeted protection against the infection. The tetanus toxoid component teaches the immune system to recognise and neutralise the toxin produced by tetanus-causing bacteria. This helps protect against the severe muscle stiffness and spasms caused by tetanus. Together, these components help the immune system develop immune memory. If your child encounters one of these infections in the future, the immune system can recognise the relevant germ or toxin more quickly and respond before severe disease develops.
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Consult your doctor

-

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Driving

Not applicable

-

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Liver

Consult your doctor

Please inform your doctor before using Tritanrix HB Injection if your child has kidney problems.

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Kidney

Consult your doctor

Please inform your doctor before using Tritanrix HB Injection if your child has liver impairment.

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Children

Consult your doctor

Tritanrix HB Injection is typically given to infants from 6 weeks old. Please consult your doctor if you have concerns using Tritanrix HB Injection in children.

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Heart

Safe if prescribed

Tritanrix HB Injection can generally be used in patients with heart problems, but only under close medical supervision.

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Geriatrics

Safe if prescribed

Tritanrix HB Injection is generally safe for geriatric individuals. Please consult your doctor if you have any concerns.

What if I have taken an overdose of Tritanrix HB Injection

Because this vaccine is administered by a trained healthcare professional, an incorrect or excessive dose is uncommon. If you suspect that your child has received an incorrect amount, inform the healthcare provider promptly so that the child can be assessed and monitored if necessary.

Diet & Lifestyle Advise

  • Keep your child hydrated: Offer breast milk, formula, or water as appropriate for your child's age and usual feeding routine after vaccination.
  • Choose comfortable clothing: Dress your child in loose, comfortable clothing that does not rub against the injection site.
  • Soothe the injection site: A cool, damp cloth can be placed gently over the injection site for a few minutes to help reduce soreness or swelling.
  • Allow quiet rest: Encourage quiet play and rest after vaccination if your child feels tired or uncomfortable.
     
health query

Have a query?

How Soon It Starts Working

The time required for Tritanrix HB Injection to start to work: The time required for Tritanrix HB Injection to show its action is unknown. The time for which the effects of Tritanrix HB Injection last: The duration of action for Tritanrix HB Injection is unknown.

What if you forget to take Tritanrix HB Injection

If a scheduled dose is missed, contact your healthcare provider as soon as possible to reschedule it. Do not give an extra dose to make up for a missed dose. A delayed vaccination generally does not mean that the entire series needs to be started again; your doctor can advise how to continue the schedule.

Storage

•Store Tritanrix HB Injection in a refrigerator between 2°C and 8°C, unless the specific product label states otherwise.

Drug Warnings

  • Check the vaccine before use: The healthcare professional should inspect the vial or syringe before administration and should not use it if there are unexpected particles, unusual discolouration, damaged packaging, or other visible problems.
  • Check the expiry date: Make sure the vaccine is within its expiry date before it is administered.
  • Avoid rubbing the injection site: Do not rub the injection site after vaccination, as this may increase local irritation.
  • Use a sterile needle: A new sterile needle and appropriate injection equipment should be used for each injection.
  • Stay for observation: Keep your child at the vaccination clinic for about 15 to 30 minutes after the injection when advised, so that any immediate allergic reaction can be recognised and treated promptly.
  • Tell your doctor about previous serious reactions: Do not give this vaccine if your child previously had a severe allergic reaction to a previous dose or to an ingredient in the vaccine.
  • Know the pertussis-related contraindication: Do not give another pertussis-containing vaccine if your child developed encephalopathy (a serious brain disorder causing reduced consciousness or major changes in brain function) within 7 days of a previous pertussis-containing vaccine and no other cause was identified.
  • Discuss neurological conditions: Tell your doctor if your child has an unstable or progressive neurological disorder or uncontrolled seizures. A stable seizure disorder by itself does not automatically mean that this vaccine cannot be given, but your child's doctor should assess the situation before vaccination.
  • Discuss immune problems: Tell your doctor if your child has a weakened immune system or is taking medicines that suppress immune activity. These factors may affect the immune response to vaccination.
  • Know when to seek urgent care: Consult your doctor right away if your child develops a severe allergic reaction, seizure, unusual unresponsiveness, or another serious symptom after vaccination.

 

verifiedApollotooltip
  • Medicines that weaken the immune system (e.g., high-dose corticosteroids, chemotherapy medicines): These medicines may reduce the immune response to Tritanrix HB Injection, which can make the vaccine less effective. Tell your doctor about all medicines your child is taking.
  • Other routine childhood vaccines: Tritanrix HB Injection can generally be given alongside other recommended vaccines when appropriate. Different vaccines may need to be given at separate injection sites using separate syringes. Your healthcare provider will determine the appropriate vaccination plan.

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verifiedApollotooltip
  • No clinically significant food interactions are known with Tritanrix HB Injection when used as directed.

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Habit Forming

No

Therapeutic Class

[IMMUNIZING AGENTS]

FAQs

Tritanrix HB Injection is used to prevent tetanus, diphtheria, pertussis, and hepatitis B infections.
Tritanrix HB Injection works by injecting the body with a small dose of the virus or its protein, helping to provide immunity or resistance against these infections. The viral vaccine can be an inactivated or killed virus (unable to replicate) or an attenuated/live virus (cannot cause the disease but can induce an immune response).
The hepatitis B vaccine stimulates the immune system to produce antibodies that fight the hepatitis B virus, providing long-term protection. In contrast, hepatitis B immunoglobulin offers immediate protection by injecting antibodies that combat the virus, typically used when swift action is necessary.
Tritanrix HB Injection will be administered by the doctor or healthcare professional only.
Hepatitis B can be life-threatening if it leads to complications like liver failure, cirrhosis (scarring), or liver cancer, especially in chronic cases.
The common side effects of Tritanrix HB Injection may include pain at the injection site or discomfort, redness or swelling at the injection site, fever, drowsiness, irritability, and unusual crying. These side effects are not familiar to everyone and vary individually. If you notice any side effects in your child that are not manageable, please consult your doctor.
A mild illness such as a common cold or slight runny nose usually does not mean that vaccination needs to be delayed. However, if your child has a moderate or severe illness, particularly with a high fever, your doctor may recommend waiting until your child has recovered.
The number and timing of doses depend on your child's age, previous vaccination history, and the national immunisation schedule being followed. Your healthcare provider will establish the appropriate schedule for your child.
The timing of combination vaccination depends on the specific vaccine and the applicable immunisation schedule. Hepatitis B vaccination is commonly started at birth, while combination vaccines containing diphtheria, tetanus, pertussis, and hepatitis B may be introduced later in infancy. Your doctor will advise when this particular combination should be given.
Yes, Tritanrix HB Injection can generally be administered alongside other recommended childhood vaccines when appropriate. Vaccines given during the same visit may need to be injected at different sites using separate syringes. Your healthcare provider will determine the appropriate schedule.
A mild fever can occur as the immune system responds to the vaccine. Keep your child comfortable and offer appropriate fluids. If the fever is very high, persists, causes significant distress, or is accompanied by a seizure, unusual unresponsiveness, or another concerning symptom, consult your doctor promptly.
No. The vaccine contains toxoids and non-live vaccine components designed to teach the immune system to recognise and fight the relevant infections. It cannot cause diphtheria, tetanus, pertussis, or hepatitis B.
If a dose is missed, contact your healthcare provider and arrange the next dose as soon as appropriate. You generally do not need to restart the entire vaccination series because of a delay. Your doctor can adjust the schedule to provide the remaining doses.
Yes, additional booster vaccination may be needed because protection against some vaccine-preventable diseases can decrease over time. Booster doses are given according to the relevant national immunisation schedule and may use age-appropriate vaccines such as DTaP, DT, Td, or Tdap rather than this exact combination. Your child's doctor will advise which booster is due and when it should be given.
Tell your doctor before giving another pertussis-containing vaccine. If your child developed encephalopathy (a serious brain disorder causing reduced consciousness or major changes in brain function) within 7 days of a previous pertussis-containing vaccine and no other cause was identified, further pertussis-containing vaccination is contraindicated. Your doctor can advise on alternative vaccination options for protection against the other diseases.
A history of seizures does not automatically mean that the vaccine cannot be given. However, tell your doctor about your child's seizure history or any neurological condition. An unstable or progressive neurological disorder or uncontrolled seizures may require further assessment before vaccination.
Most children experience only mild, temporary effects such as soreness, fever, or irritability after vaccination. Serious reactions are uncommon. If your child develops a concerning symptom that persists or becomes worse, consult your doctor for assessment.

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Country of origin

India

Manufacturer/Marketer address

SCO-61 2nd Floor, Swastik Vihar MDC SEC-5 Panchkula, Haryana - 134114
Other Info - TR67627
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