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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Trofame XR Capsule is used to treat overactive bladder (OAB) symptoms such as frequent urination, involuntary loss of urine, an urgent and uncontrollable need to urinate, or bedwetting. It relaxes the involuntary muscle (detrusor) in the bladder wall and reduces unstable and involuntary contractions of the bladder, and increases the bladder's capacity to hold urine. Thus, it decreases the need to urinate. It may cause side effects such as dry mouth, nausea, stomach pain, indigestion, or constipation.
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Composition :

TROSPIUM-60MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Trofame XR Capsule

Trofame XR Capsule belongs to the class of drugs called antimuscarinics used to treat overactive bladder (OAB) symptoms. Overactive bladder is a problem with bladder function that causes a sudden urge to urinate. Overactive bladder symptoms include frequent urination, involuntary loss of urine, an urgent and uncontrollable need to urinate, or bedwetting.

Trofame XR Capsule contains Trospium which works by blocking muscarinic receptors on the surface of muscle cells and inhibits the action of acetylcholine (a chemical messenger) that causes contraction of the bladder muscle. Thereby, Trofame XR Capsule relaxes the involuntary muscle (detrusor) in the bladder wall and reduces unstable and involuntary contractions of the bladder, and increases the bladder's capacity to hold urine. Thus, it decreases the need to urinate.

Take Trofame XR Capsule as prescribed by your doctor. You are advised to take Trofame XR Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dry mouth, nausea, stomach pain, indigestion, or constipation. Most of these side effects of Trofame XR Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Trofame XR Capsule or any other medicines, please tell your doctor. Trofame XR Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.  Please consult a doctor if you are pregnant or breastfeeding before taking Trofame XR Capsule . Do not consume alcohol with Trofame XR Capsule as it may increase the risk of adverse effects. You are recommended to drink plenty of water while taking Trofame XR Capsule to prevent dryness of the mouth. Drive only if your vision is clear after taking Trofame XR Capsule as it may cause blurred vision in some people for a short duration.

Uses of Trofame XR Capsule

Treatment of Overactive bladder

Directions for Use

Take Trofame XR Capsule on empty stomach before a meal as prescribed by your doctor and swallow whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Trofame XR Capsule contains Trospium used to treat overactive bladder symptoms.  Trofame XR Capsule blocks muscarinic receptors on the muscle cells and inhibits the action of acetylcholine (a chemical messenger) that causes contraction of the bladder muscle. Thereby, Trofame XR Capsule relaxes the involuntary muscle (detrusor) in the bladder wall and reduces unstable and involuntary contractions of the bladder and increases bladder capacity to hold urine. Thus, it decreases the need to urinate.

How Trofame XR Capsule Works

Trofame XR Capsule contains Trospium which works by blocking muscarinic receptors on the surface of muscle cells and inhibits the action of acetylcholine (a chemical messenger) that causes contraction of the bladder muscle. Thereby, Trofame XR Capsule relaxes the involuntary muscle (detrusor) in the bladder wall and reduces unstable and involuntary contractions of the bladder, and increases the bladder's capacity to hold urine. Thus, it decreases the need to urinate.

Storage

Store in a cool and dry place away from sunlight
Side effects of Trofame XR Capsule
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Eat smaller, more frequent meals.
  • Eat slowly and chew your food thoroughly to help digestion.
  • Eat fiber-rich foods such as fruits, whole grains, and vegetables to promote regular bowel movements.
  • Avoid gas-producing foods like cabbage, beans, broccoli and carbonated drinks.
  • Drink lots of water throughout the day to prevent dehydration and aid digestion.
  • Do regular exercise to enhance digestion and reduce bloating.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Trofame XR Capsule

Do not take more than the prescribed dose of Trofame XR Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Trofame XR Capsule or any other medicines, please tell your doctor. If you have nerve damage, overactive thyroid,  hernia of the diaphragm with inflammation of the esophagus, liver, kidney, or heart problems, inform your doctor before taking Trofame XR Capsule . Trofame XR Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.  Please consult a doctor if you are pregnant or breastfeeding before taking Trofame XR Capsule . Do not consume alcohol with Trofame XR Capsule as it may increase the risk of adverse effects. You are recommended to drink plenty of water while taking Trofame XR Capsule to prevent dryness of the mouth. Avoid taking Trofame XR Capsule if you have urinary retention, serious liver disorder, narrow-angle glaucoma, irregular heartbeats, myasthenia gravis (muscle weakness), and toxic megacolon (severe gastrointestinal condition). Drive only if your vision is clear after taking Trofame XR Capsule as it may cause blurred vision in some people for a short duration.

Drug-Drug Interactions

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TrospiumPotassium chloride
Critical
TrospiumPotassium citrate
Critical

Drug-Drug Interactions

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TrospiumPotassium chloride
Critical
How does the drug interact with Trofame XR Capsule:
Taking Trofame XR Capsule with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Trofame XR Capsule with Potassium chloride is not recommended as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
TrospiumPotassium citrate
Critical
How does the drug interact with Trofame XR Capsule:
Taking Potassium citrate and Trofame XR Capsule together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Trofame XR Capsule with Potassium citrate is not recommended as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
TrospiumZonisamide
Severe
How does the drug interact with Trofame XR Capsule:
Coadministration of Trofame XR Capsule with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Trofame XR Capsule with Zonisamide together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
TrospiumProcainamide
Severe
How does the drug interact with Trofame XR Capsule:
Using Trofame XR Capsule together with procainamide may increase the blood levels and effects of both the drugs.

How to manage the interaction:
There may be a possibility of interaction between Trofame XR Capsule and Procainamide, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without a doctor's advice.
TrospiumTopiramate
Severe
How does the drug interact with Trofame XR Capsule:
Taking Trofame XR Capsule with Topiramate can cause increase in body temperature and decrease sweating.

How to manage the interaction:
Although taking Trofame XR Capsule and Topiramate together can evidently cause an interaction, but it should be taken if your doctor has suggested it. However, if you experience feeling sweating, feeling very tired, dizzy or lightheaded, or having trouble thinking clearly contact your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Pelvic floor exercises would help treat bladder spasms.
  • Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, chocolate and tea.
  • Limit fluid intake as excess fluid intake could cause an urge to urinate frequently.
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, and exercise regularly.
  • Avoid smoking and alcohol intake.
  • Take 6-8 glasses of liquids every day.
  • Avoid processed foods. Instead, choose whole, unprocessed foods.
  • Include fruits, vegetables, and fiber-rich food in your diet.

Habit Forming

No

Therapeutic Class

ANTIMUSCARINIC AGENTS

Trofame XR Capsule Substitute

Substitutes safety advice
  • TROPEZ OD TABLET

    by Others

    4.68per tablet
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Trofame XR Capsule as it may increase the risk of adverse effects of Trofame XR Capsule .

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Pregnancy

Caution

Trofame XR Capsule is a category C pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. However, please consult a doctor if you are pregnant.

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Breast Feeding

Caution

It is unknown whether Trofame XR Capsule is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding. Trofame XR Capsule is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Caution

Trofame XR Capsule may cause blurred vision in some people. Therefore, wait until your vision is clear before driving or operating heavy machinery.

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Liver

Caution

Take Trofame XR Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Trofame XR Capsule if you have severe liver disease.

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Kidney

Caution

Take Trofame XR Capsule with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Trofame XR Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.

FAQs

Trofame XR Capsule is used to treat overactive bladder (OAB) symptoms.

Trofame XR Capsule contains Trospium that works by relaxing the involuntary muscle (detrusor) in the bladder wall responsible for overactive bladder by contracting in uncontrollable spasms. Thereby, Trofame XR Capsule reduces the bladder's involuntary and unstable contractions and increases bladder capacity to hold urine. Thus, it decreases the need to urinate.

Trofame XR Capsule may cause dryness of the mouth as a side effect. It is not necessary for everyone taking Trofame XR Capsule to experience this side effect. Therefore, drink plenty of water, chew sugar-free gum or candy, limit caffeine intake, avoid smoking and alcohol-containing mouthwashes to prevent dry mouth.

You are not recommended to take Trofame XR Capsule with diphenhydramine (anti-allergic drug) as co-administration of these two medicines may increase adverse effects such as blurred vision, dry mouth, drowsiness, decreased sweating, confusion, irregular heartbeat, memory problems or constipation. However, please consult a doctor before taking Trofame XR Capsule with other medicines.

Trofame XR Capsule may increase the risk of heatstroke as it may decrease sweating and leads to overheating. Therefore, drink plenty of water while taking Trofame XR Capsule to prevent dehydration and avoid becoming dehydrated or overheated during exercise and in hot weather.

Trofame XR Capsule is not recommended for patients suffering from narrow-angle glaucoma as it may worsen the condition. Therefore, inform your doctor if you have glaucoma or any other eye problems before taking Trofame XR Capsule .

Trofame XR Capsule may cause temporary blurred vision in some patients. However, avoid driving or operating machinery until your vision is clear.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - TRO0079

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