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Trombopag 50 Tablet 7's

Trombopag 50 Tablet 7's

Prescription drug
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Composition

ELTROMBOPAG-50MG

Manufacturer/Marketer

Natco Pharma Limited

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

About Trombopag 50 Tablet 7's

Trombopag 50 Tablet 7's belongs to the class of 'platelet-stimulating agents' primarily used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Trombopag 50 Tablet 7's is also used to treat severe aplastic anaemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused due to hepatitis C virus. Severe aplastic anaemia is a condition in which the bone marrow doesn't make enough blood cells.

Trombopag 50 Tablet 7's contains 'Eltrombopag' which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet's production. Trombopag 50 Tablet 7's works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Trombopag 50 Tablet 7's helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

Take Trombopag 50 Tablet 7's as prescribed by your doctor. In some cases, Trombopag 50 Tablet 7's can cause common side effects like nausea, diarrhoea, headache, muscle pain, tiredness, loss of appetite, fever, anaemia (lack of blood cells), cough and tingling numbness. These side effects are not familiar to everyone who take Trombopag 50 Tablet 7's and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you have any allergic reactions to Trombopag 50 Tablet 7's or any other medicines, before starting Trombopag 50 Tablet 7's. It is essential to inform your doctor if you have any heart, kidney or liver problems, blood disorders, blood clotting problems and cataracts before starting Trombopag 50 Tablet 7's. It is advised to consult the doctor if you are pregnant or planning to conceive. Trombopag 50 Tablet 7's is not indicated for use in breastfeeding since it passes into the breast milk. Trombopag 50 Tablet 7's may make you dizzy, hence drive or operate machinery only when you are mentally alert. 

Uses of Trombopag 50 Tablet 7's

Treatment of Low platelet count and Severe aplastic anaemia (SAA).

Medicinal Benefits

Trombopag 50 Tablet 7's contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA) in adults. Trombopag 50 Tablet 7's works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets. The increase in these bone marrow cells stimulates the production of platelets. Thus Trombopag 50 Tablet 7's prevents bleeding episodes by increasing the number of platelets in the blood.

Directions for Use

Tablet: Swallow it as a whole with a glass of water. Take it on an empty stomach as prescribed by the doctor. Do not crush, chew or break it. Oral suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.Powder: Mix the powder with the prescribed amount of water. Take it with or without food with an oral syringe in the dose and duration prescribed by the doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trombopag 50 Tablet 7's

  • Nausea
  • Diarrhoea
  • Headache
  • Muscle pain
  • Tiredness
  • Loss of appetite
  • Fever
  • Anaemia (lack of blood cells)
  • Cough
  • Tingling or numbness 

Drug Warnings

If you are known to be allergic to Trombopag 50 Tablet 7's or other medicines, please inform your doctor in advance. Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Trombopag 50 Tablet 7's. Take Trombopag 50 Tablet 7's at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Trombopag 50 Tablet 7's. Trombopag 50 Tablet 7's is not recommended during pregnancy since it may have harmful effects on the foetus. Consult your doctor before using Trombopag 50 Tablet 7's if you are a breastfeeding mother. Do not drive or operate machinery since Trombopag 50 Tablet 7's may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive. Avoid or limit alcohol consumption with Trombopag 50 Tablet 7's as it may affect the efficacy of Trombopag 50 Tablet 7's. Trombopag 50 Tablet 7's is not recommended for children less than one year of age in ITP and children less than two years of age in SAA. 

Drug Interactions

Drug-Drug Interaction: Trombopag 50 Tablet 7's may interact with antacids, cholesterol-lowering drugs (statins), vitamin and mineral supplements (iron, calcium, magnesium, aluminium, selenium and zinc), anti-cancer drugs (methotrexate, topotecan), drugs for rheumatoid arthritis (ciclosporin, azathioprine), HIV/AIDS drugs (lopinavir, ritonavir), corticosteroids, and steroid hormones (danazol).

Drug-Food Interaction: Take Trombopag 50 Tablet 7's at least two hours before or four hours after consuming dairy products, calcium-enriched foods, and fortified juices since they interfere with the absorption of Trombopag 50 Tablet 7's.

Drug-Disease Interaction: People with blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, and liver or kidney diseases should consult the doctor before taking Trombopag 50 Tablet 7's.

Drug-Drug Interactions Checker List

  • METHOTREXATE
  • TOPOTECAN
  • CICLOSPORIN
  • AZATHIOPRINE
  • LOPINAVIR
  • RITONAVIR
  • DANAZOL
  • IRON
  • CALCIUM
  • ZINC

Habit Forming

No

Diet & Lifestyle Advise

  • Eat natural and healthy foods by cutting down on fatty and sodium processed foods.
  • Exercise regularly to maintain good health.
  • Avoid smoking and alcohol intake.
  • Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
  • High protein diet such as lean meat, chicken, crab, turkey, beef and fish can help increase the platelet count.
  • Eating Papaya is the best natural remedy to increase your platelet count, you can also use papaya leave's mixture.
  • Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
  • Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit and broccoli can also boost your platelet count.

Special Advise

  • Keep a check on your daily blood pressure and blood sugar levels and if you notice any fluctuations, please consult a doctor.
  • Since Trombopag 50 Tablet 7's affects liver enzymes, your doctor may suggest liver function tests to check your aspartate aminotransferase (AST), alanine aminotransferase (ALT) and bilirubin levels before starting treatment and every two weeks after the treatment with Trombopag 50 Tablet 7's.
  • Trombopag 50 Tablet 7's may also interfere with creatinine and bilirubin lab tests, hence, please inform your doctor and laboratory staff in advance.

Disease/Condition Glossary

Immune (idiopathic) thrombocytopenic purpura (ITP): It is an immune condition associated with low levels of platelets, and the blood doesn't clot normally. It occurs when the immune system mistakenly attacks its own platelets. ITP also occurs in children, followed by a viral infection. Symptoms of ITP may include easy bruising, bleeding from gums and nose, blood in urine and stools, heavy menstrual flow and pinpoint-sized reddish-purple spots on the lower legs.

Hepatitis C: It is an infection and inflammation of the liver caused due to hepatitis C virus. This virus can cause both acute and chronic hepatitis. Acute hepatitis C is a short term illness that may range for six months. Chronic hepatitis C is a long-lasting disease that may lead to other severe liver cancer problems or cirrhosis (inflammation of the liver). Symptoms of hepatitis C include fatigue, nausea, loss of appetite and yellowing of the eyes and skin.

Severe aplastic anaemia (SAA): Aplastic anaemia is also called bone marrow aplasia. It is a condition in which the bone marrow doesn't make enough blood cells. SAA is commonly caused due to the damage of bone marrow. This damage can be a congenital disability or may occur because of radiation, chemotherapy, toxic chemicals, certain drugs and infections. Symptoms of SAA include fatigue, frequent infections, rapid heart rate and bleeding. 

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Alcohol

Caution

Limit alcohol intake, along with Trombopag 50 Tablet 7's, to attain the maximum efficacy of Trombopag 50 Tablet 7's and rule out any possibility of worsening of side effects.

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Pregnancy

Unsafe

Trombopag 50 Tablet 7's is not recommended in pregnancy. It may affect and harm the developing baby. Please consult your doctor if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Trombopag 50 Tablet 7's is excreted into the breast milk. Please consult your doctor for more information before taking Trombopag 50 Tablet 7's if you are a nursing mother.

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Driving

Caution

Trombopag 50 Tablet 7's may cause dizziness and tiredness affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Trombopag 50 Tablet 7's. Trombopag 50 Tablet 7's may cause an increase in liver enzymes. Your doctor may start the treatment with a lower dose of Trombopag 50 Tablet 7's.

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Kidney

Caution

Trombopag 50 Tablet 7's should be used with caution in cases of renal impairment. It is advised to seek doctor advice before starting Trombopag 50 Tablet 7's if you have any kidney problems.

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Children

Caution

Trombopag 50 Tablet 7's is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info -

Author Details

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FAQs

Trombopag 50 Tablet 7's contains Eltrombopag that stimulates platelet's production (helps in clotting) from megakaryocytes (bone marrow cells). Thus Trombopag 50 Tablet 7's lowers the risk of bleeding episodes in diseases like immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA).
Do not stop using Trombopag 50 Tablet 7's even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.
Trombopag 50 Tablet 7's should be used with caution and only under doctor's supervision in cases of any allergic reactions, blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases.
Trombopag 50 Tablet 7's decreases the risk of bleeding by increasing the platelet count in your body. However, you are advised to stay away from activities that may increase your risk of bleeding like contact sports and using sharp objects like razors and nail cutters.
It is advised to take Trombopag 50 Tablet 7's on an empty stomach. Please take Trombopag 50 Tablet 7's at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Trombopag 50 Tablet 7's.

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