Trombopag 50 Tablet 7's
MRP ₹3500
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About Trombopag 50 Tablet
Trombopag 50 Tablet is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Trombopag 50 Tablet is also used to treat severe aplastic anaemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused by the hepatitis C virus. Severe aplastic anaemia is a condition in which the bone marrow doesn't make enough blood cells.
Trombopag 50 Tablet contains 'Eltrombopag', which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone, stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet production. Trombopag 50 Tablet works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Trombopag 50 Tablet helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.
In some cases, Trombopag 50 Tablet can cause common side effects like nausea, diarrhea, headache, muscle pain, tiredness, loss of appetite, fever, anaemia (lack of blood cells), cough and tingling numbness. If you notice any side effects that are not manageable, please consult your doctor.
Let your doctor know if you have any allergic reactions to Trombopag 50 Tablet or any other medicines before starting Trombopag 50 Tablet. Consult the doctor if you are pregnant or planning to conceive. Trombopag 50 Tablet is not indicated for use in breastfeeding since it passes into the breast milk.
Uses of Trombopag 50 Tablet
Trombopag 50 Tablet is used in the treatment of low platelet count (thrombocytopenia) in various blood-related disorders. The detailed uses of Trombopag 50 Tablet are as follows:
- Treats Chronic Immune Thrombocytopenia (ITP): Trombopag 50 Tablet is used to treat chronic ITP in patients who have not responded adequately to treatments such as immunoglobulins, corticosteroids, and splenectomy (surgical removal of spleen).
- Manages Thrombocytopenia in Hepatitis C Virus (HCV) infection: Trombopag 50 Tablet helps increase platelet counts in chronic HCV patients, making it safer for them to start and continue treatment with interferon.
- Treats Severe Aplastic Anaemia (SAA): Trombopag 50 Tablet is used for patients with SAA who have not responded to immunosuppressive treatment, helping to stimulate bone marrow to produce more blood cells.
- Prevents Bleeding Episodes: By increasing platelet count, Trombopag 50 Tablet reduces the risk of bleeding associated with low platelet levels in various blood disorders.
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Directions for Use
- Trombopag 50 Tablet can be taken on an empty stomach, at least 1 hour before or 2 hours after eating.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Trombopag 50 Tablet as a whole with a glass of water.
- Do not crush, break, or chew it.
Key Benefits
- Trombopag 50 Tablet contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA) in adults.
- Trombopag 50 Tablet works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets.
- The increase in these bone marrow cells stimulates the production of platelets. Thus Trombopag 50 Tablet prevents bleeding episodes by increasing the number of platelets in the blood.
How Trombopag 50 Tablet Works
Storage
- Get plenty of rest and sleep.
- Keep your body warm.
- Drink plenty of fluids to stay hydrated.
- Avoid strenuous activities.
- Maintain good hygiene to prevent flu from spreading.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
- Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
- Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
- Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
- If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
- Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
- Tell your doctor about your depression symptoms to adjust medication.
- Consult a therapist or counsel for emotional support.
- Engage in regular exercise to release endorphins (neurotransmitters).
- Practice stress-reducing techniques like meditation and deep breathing.
- Build a support network of friends, family, and support groups.
- Establish a consistent sleep schedule.
- Eat a nutritious diet rich in fruits, vegetables, and whole grains.
- Limit or avoid alcohol and recreational substances.
- Keep a mood journal to track symptoms and progress.
- Inform your doctor about the symptoms you're experiencing due to medication.
- Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
- Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
- Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
- Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
What if I have taken an overdose of Trombopag 50 Tablet
Drug Warnings
- If you are known to be allergic to Trombopag 50 Tablet or other medicines, please inform your doctor in advance.
- Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Trombopag 50 Tablet.
- Take Trombopag 50 Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Trombopag 50 Tablet.
- Trombopag 50 Tablet is not recommended during pregnancy since it may have harmful effects on the foetus.
- Consult your doctor before using Trombopag 50 Tablet if you are a breastfeeding mother.
- Do not drive or operate machinery since Trombopag 50 Tablet may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive.
- Avoid or limit alcohol consumption with Trombopag 50 Tablet as it may affect the efficacy of Trombopag 50 Tablet.
- Trombopag 50 Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.
Drug-Drug Interactions
Drug-Drug Interactions
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Ferric maltol can make Trombopag 50 Tablet less effective by reducing its absorption and lowering its concentration in the blood. This can lead to poor treatment outcomes.
How to manage the interaction:
Taking Ferric maltol with Trombopag 50 Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Trombopag 50 Tablet on an empty stomach at least 2 hours before or 4 hours after ferric maltol. Do not discontinue any medication without consulting a doctor.
Taking magnesium citrate with Trombopag 50 Tablet can make it less effective by reducing its absorption and lowering its concentration in the blood.
How to manage the interaction:
Taking Magnesium citrate with Trombopag 50 Tablet is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. You should take Trombopag 50 Tablet on an empty stomach at least 2 hours before or 4 hours after magnesium citrate. Do not discontinue any medication without consulting a doctor.
When Trombopag 50 Tablet is mixed with Calcium chloride, the amount of Trombopag 50 Tablet in the blood can decrease. This can lead to low treatment outcomes.
How to manage the interaction:
Taking Trombopag 50 Tablet with calcium chloride is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
Coadministration of Magnesium oxide with Trombopag 50 Tablet can impair the absorption of Trombopag 50 Tablet which leads to increased levels in the blood. This can increase the risk and severity of side effects.
How to manage the interaction:
Taking Magnesium oxide with Trombopag 50 Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Trombopag 50 Tablet and aluminum hydroxide may interfere with the absorption of Trombopag 50 Tablet and reduce its effectiveness.
How to manage the interaction:
Taking Trombopag 50 Tablet with aluminum hydroxide is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
Ferrous gluconate can make Trombopag 50 Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.
How to manage the interaction:
Taking Trombopag 50 Tablet with Ferrous gluconate is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Trombopag 50 Tablet on an empty stomach at least 2 hours before or 4 hours after ferrous gluconate. Do not discontinue any medication without consulting a doctor.
When Interferon alfa-2b is taken with Trombopag 50 Tablet, it can lower the metabolism of Trombopag 50 Tablet.
How to manage the interaction:
There may be a possibility of interaction between Trombopag 50 Tablet and Interferon alfa-2b, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to call a doctor right away. These symptoms include chronic hepatitis C, advanced liver disease, cirrhosis, liver failure, and other liver-related problems. You should also seek medical attention if you experience confusion, fever, joint pain, swelling, or any other unusual symptoms. Do not discontinue any medications without consulting a doctor.
Coadministration of Trombopag 50 Tablet and Interferon alfa-n1 can increase the risk or severity of liver damage.
How to manage the interaction:
Although taking Trombopag 50 Tablet and Interferon alfa-n1 together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
Coadministration of Trombopag 50 Tablet with Interferon alfa-2a can increase the risk or severity of liver injury.
How to manage the interaction:
Although there is a possible interaction between Trombopag 50 Tablet and Interferon alfa-2a, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
When Eluxadoline is taken with Trombopag 50 Tablet, the amount of Eluxadoline in the blood can go up. This can increase the risk or severity of side effects.
How to manage the interaction:
Although taking Trombopag 50 Tablet and Eluxadoline together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like dizziness, drowsiness, nausea, vomiting, constipation, or abdominal pain, call a doctor right away. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Eat natural and healthy foods by cutting down on fatty and sodium-processed foods.
- Exercise regularly to maintain good health.
- Avoid smoking and alcohol intake.
- Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
- A high-protein diet, such as lean meat, chicken, crab, turkey, beef and fish, can help increase platelet count.
- Eating Papayaa is the best natural remedy to increase your platelet count, and you can also use Papayaa leaves mixture.
- Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
- Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit and broccoli can also boost your platelet count.
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Alcohol
Safe if prescribed
Limit alcohol intake, along with Trombopag 50 Tablet, to attain the maximum efficacy of Trombopag 50 Tablet and rule out any possibility of worsening of side effects.
Pregnancy
Consult your doctor
Trombopag 50 Tablet is not recommended in pregnancy. It may affect and harm the developing baby. Please consult your doctor if you are pregnant or planning to conceive.
Breast Feeding
Consult your doctor
It is not known if Trombopag 50 Tablet is excreted into the breast milk. Please consult your doctor for more information before taking Trombopag 50 Tablet if you are a nursing mother.
Driving
Safe if prescribed
Trombopag 50 Tablet may cause dizziness and tiredness affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.
Liver
Consult your doctor
Let your doctor know if you have any history of liver diseases before taking Trombopag 50 Tablet. Trombopag 50 Tablet may cause an increase in liver enzymes. Your doctor may start the treatment with a lower dose of Trombopag 50 Tablet.
Kidney
Consult your doctor
Trombopag 50 Tablet should be used with caution in cases of renal impairment. It is advised to seek doctor advice before starting Trombopag 50 Tablet if you have any kidney problems.
Children
Safe if prescribed
Trombopag 50 Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.
Heart
Please inform your doctor if you have a history of heart disease before using Trombopag 50 Tablet. Your doctor will prescribe it only if the benefits outweigh the risks.
Geriatrics
Consult your doctor
Trombopag 50 Tablet is safe for use in elderly patients if prescribed by the physician.
FAQs
Trombopag 50 Tablet is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. It is also used to treat severe aplastic anemia (SAA) in adults.
Trombopag 50 Tablet contains Eltrombopag that stimulates platelet's production (helps in clotting) from megakaryocytes (bone marrow cells). Thus Trombopag 50 Tablet lowers the risk of bleeding episodes in diseases like immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA).
Do not stop using Trombopag 50 Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.
Trombopag 50 Tablet should be used with caution and only under doctor's supervision in cases of any allergic reactions, blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases.
Trombopag 50 Tablet decreases the risk of bleeding by increasing the platelet count in your body. However, you are advised to stay away from activities that may increase your risk of bleeding like contact sports and using sharp objects like razors and nail cutters.
It is advised to take Trombopag 50 Tablet on an empty stomach. Please take Trombopag 50 Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Trombopag 50 Tablet.
Trombopag 50 Tablet should be swallowed whole. Do not chew or crush the tablets.
It is usually taken once a day on an empty stomach, at least 1 hour before or 2 hours after eating. Take Trombopag 50 Tablet at around the same time every day.
It may take up to 2 weeks for patients to respond to Trombopag 50 Tablet.
Trombopag 50 Tablet should not be taken with foods, beverages, or other medicines that contain high concentrations of aluminium, calcium, iron, magnesium, selenium and zinc.
Trombopag 50 Tablet should be stored in a cool and dry place away from sunlight. Keep out of sight and reach of children.
Trombopag 50 Tablet can cause or increase the risk of severe liver issues. Check with your doctor straight away if you or your child experience nausea or vomiting, dark urine, light-coloured stools, right upper stomach pain, unusual exhaustion, or yellow eyes or skin while taking this medication.
Please take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
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