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  3. Trustiva Tablet 30's

Trustiva Tablet 30's, Pack of 1 TABLET
Trustiva Tablet 30's, Pack of 1 TABLET
Trustiva Tablet 30's, Pack of 1 TABLET
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Trustiva Tablet belongs to the class of antiretroviral drugs used in the treatment of HIV infection. This combination medicine work by inhibiting the reverse transcriptase enzyme production, which is necessary for the multiplication of the viruses. Common side effects include dizziness, headache, diarrhoea, nausea, vomiting, rashes, and feeling weak
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Composition :

EFAVIRENZ-600MG + EMTRICITABINE-200MG + TENOFOVIR DISOPROXIL FUMARATE-300MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Trustiva Tablet

Trustiva Tablet belongs to the class of medicines called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

Trustiva Tablet contains Emtricitabine, Tenofovir Disoproxil Fumarate and Efavirenz. Efavirenz is a non-nucleoside reverse transcriptase inhibitor, Emtricitabine is a nucleoside reverse transcriptase inhibitor, and Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme production, which is necessary for the multiplication of the viruses. This effect helps to inhibit viral replication.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Trustiva Tablet are dizziness, headache, diarrhoea, nausea, vomiting, rashes (red spots or blotches, sometimes with blistering and swelling of the skin), and feeling weak. These side effects usually resolve without requiring any medical attention. However, if any of these side effects persist or worsen, inform your doctor immediately.

Trustiva Tablet is not recommended to take Trustiva Tablet if you are allergic to any contents of it. Trustiva Tablet is not recommended for use in lactating mothers, children and adolescents under 18 years of age. Trustiva Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Consumption of alcohol may increase the risk of side effects; therefore, avoid alcohol consumption.

Uses of Trustiva Tablet

Treatment of HIV infection

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Directions for Use

• Take Trustiva Tablet on empty stomach 1hour before or 2hours after food.• Trustiva Tablet should be taken once daily preferably at the bedtime.• Swallow it as a whole with a glass of water.• Do not break, crush or chew it.

Medicinal Benefits

Trustiva Tablet belongs to the group of medicines called antiretroviral therapy. Trustiva Tablet contains Emtricitabine, Tenofovir Disoproxil Fumarate and Efavirenz. Trustiva Tablet works by inhibiting the reverse transcriptase enzyme production, which is necessary to multiply the viruses. This effect helps to inhibit viral replication and treats HIV infection.

How Trustiva Tablet Works

Trustiva Tablet contains Emtricitabine, Tenofovir Disoproxil Fumarate and Efavirenz. Efavirenz is a non-nucleoside reverse transcriptase inhibitor, Emtricitabine is a nucleoside reverse transcriptase inhibitor, and Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme production, which is necessary for the multiplication of the viruses. This effect helps to inhibit viral replication.

Storage

• Store in a cool and dry place away from sunlight.• Keep Trustiva Tablet out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Trustiva Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

What if I have taken an overdose of Trustiva Tablet

Take Trustiva Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include uncontrolled body movements, dizziness, difficulty concentrating, nervousness, confusion, forgetfulness, difficulty falling asleep or staying asleep, unusual dreams, drowsiness, hallucinations (seeing things or hearing voices that do not exist), abnormally happy mood, and strange thoughts. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Trustiva Tablet should be used with caution in patients with mental illness, fits, and liver diseases. If you notice any signs of infection, inform your doctor immediately. Autoimmune diseases (immune cells attack healthy body tissue) may occur months after the start of the treatment. Inform your doctor if you notice any signs such as muscle weakness, weakness in the hands and feet, palpitations (pounding heart), and tremors. Trustiva Tablet may cause osteonecrosis (death of bone tissue due to a decrease in blood supply to the bone) in some patients. The risk of this disease depends on factors such as length of antiretroviral therapy, alcohol use, steroid use, body mass index (BMI), and immunity. Inform your doctor if you notice joint pain, stiffness, and difficulty in movement, as these symptoms may indicate osteonecrosis.

Drug-Drug Interactions

verifiedApollotooltip
EfavirenzCisapride
Critical
EfavirenzRanolazine
Critical

Drug-Drug Interactions

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EfavirenzCisapride
Critical
How does the drug interact with Trustiva Tablet:
Taking Trustiva Tablet and Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Trustiva Tablet and Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzRanolazine
Critical
How does the drug interact with Trustiva Tablet:
When Trustiva Tablet is taken with Ranolazine, it can lower the levels of Ranolazine.

How to manage the interaction:
Taking Ranolazine with Trustiva Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.
EfavirenzErgometrine
Critical
How does the drug interact with Trustiva Tablet:
When Trustiva Tablet is taken with Ergometrine, the level of Ergometrine in the body can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ergometrine with Trustiva Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, ringing of the ears, chest pain, palpitation, or irregular heartbeats contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzVoriconazole
Critical
How does the drug interact with Trustiva Tablet:
Coadministration of Voriconazole with Trustiva Tablet can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Voriconazole with Trustiva Tablet can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
EfavirenzGrepafloxacin
Critical
How does the drug interact with Trustiva Tablet:
Taking Trustiva Tablet with Grepafloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Trustiva Tablet with Grepafloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzDienogest
Critical
How does the drug interact with Trustiva Tablet:
When Trustiva Tablet is taken with Dienogest, it can lower the metabolism of Dienogest and increase the risk or severity of side effects.

How to manage the interaction:
Taking Trustiva Tablet with Dienogest can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
EfavirenzThioridazine
Critical
How does the drug interact with Trustiva Tablet:
Taking Trustiva Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Trustiva Tablet with Thioridazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzBepridil
Critical
How does the drug interact with Trustiva Tablet:
Taking Bepridil with Trustiva Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Bepridil with Trustiva Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzZiprasidone
Critical
How does the drug interact with Trustiva Tablet:
Using ziprasidone together with Trustiva Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Trustiva Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
EfavirenzLomitapide
Critical
How does the drug interact with Trustiva Tablet:
When Trustiva Tablet is taken with Lomitapide it can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Trustiva Tablet with Lomitapide is not recommended as it results in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Consume vitamin and nutrient-rich food such as vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.
  • Make sure you sleep at least 8 hours a day.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Trustiva Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

Avoid the consumption of alcohol as it may increase the risk of side effects.

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Pregnancy

Caution

Trustiva Tablet should be used with caution in pregnant women. It is given only if clinically needed and when the benefits outweigh the risk.

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Breast Feeding

Caution

Avoid breastfeeding during treatment with Trustiva Tablet . Please seek medical advice if you have any concerns.

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Driving

Caution

Trustiva Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Trustiva Tablet should not be used in patients with severe liver diseases. In mild to moderate conditions, the dose may have to be adjusted by your doctor as required.

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Kidney

Caution

Trustiva Tablet should not be used in patients with moderate to severe kidney diseases as this medicine may affect kidney function. In mild conditions, the dose may have to be adjusted by your doctor as required.

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Children

Unsafe

Trustiva Tablet is not recommended for children and adolescents below 18 years old.

FAQs

Trustiva Tablet belongs to the class of medicines called antiretroviral agents used to treat HIV infection.

Trustiva Tablet works by inhibiting the reverse transcriptase enzyme production, which is necessary for the production of viruses. This effect helps to inhibit viral replication and treats HIV infection.

Trustiva Tablet is not recommended for patients with severe liver disease, moderate to severe kidney disease, or heart conditions such as prolonged QT interval, which increases the risk of severe heart rhythm problems, family history of heart problems, and low electrolyte levels.

Trustiva Tablet doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.

Trustiva Tablet may cause dizziness, drowsiness, difficulty sleeping, or difficulty concentrating in the first 1-2 days of treatment, and these symptoms generally go away after the first 2-4weeks. Therefore, avoid driving or operating machinery unless you are alert.

Country of origin

INDIA

Manufacturer/Marketer address

2nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - TRU0059

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 6:59 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.9129.pdf

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