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  3. Tunib 12.5 mg Capsule 28's

Tunib 12.5 mg Capsule 28's, Pack of 1 Capsule
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tunib 12.5 mg Capsule is used to treat cancer of the stomach, bowel, oesophagus, kidney, and hormone-producing cells in the pancreas. It contains sunitinib which works by slowing down the growth of cancer cells. In some cases, this medicine may cause side effects such as dry mouth, stomach upset, nausea, vomiting, diarrhoea, constipation, and loss of appetite. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

SUNITINIB-12.5MG

Manufacturer/Marketer :

Panacea Biotec Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tunib 12.5 mg Capsule

Tunib 12.5 mg Capsule belongs to the class of medications called ‘antineoplastic agents’ used in treating gastrointestinal stromal tumors (cancer of the stomach, bowel, or esophagus) in which patients don’t respond to imatinib (another anticancer agent). It is also used to treat renal carcinoma (kidney cancer) that has spread to other parts of the body and advanced pancreatic neuroendocrine tumors (cancer that has affected hormone-producing cells in the pancreas).

Tunib 12.5 mg Capsule contains sunitinib. It acts by slowing down the growth of cancer cells by two processes. It interferes with the action of a protein that promotes cell division and thereby decreases cancer cell production. It can inhibit a process called angiogenesis, the development of blood supply to the cancer cells. This effect inhibits the nutrient supply to the cancer cells, thereby causing cancer cell death eventually.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Tunib 12.5 mg Capsule are difficulty breathing, increase in blood pressure, extreme tiredness, swelling caused by fluid under the skin and around the eye, pain or irritation in the mouth, mouth sores, dry mouth, taste disturbances, upset stomach, nausea, vomiting, diarrhea, constipation, abdominal pain, loss of appetite, decreased activity of thyroid gland (hypothyroidism), dizziness, headache, nose bleeding, back pain, joint pain, pain in arms and legs, yellowish discoloration of the skin, rash on the palms of the hands and soles of the feet, dryness of the skin, cough, fever, and difficulty to sleep. Inform your doctor immediately if any of these side-effects persist or get worse.

It is not recommended to take Tunib 12.5 mg Capsule if you are allergic to any contents of it. Tunib 12.5 mg Capsule should be used with caution in patients with high blood pressure, heart problems, diabetes, liver or kidney problems, skin disorders, pancreas or gallbladder problems, history of blood clots, aneurysm (weakening of blood vessel wall), problems with the thyroid gland, pancreas, and gallbladder, liver or kidney problems, and thrombotic microangiopathy (damage to the smallest blood vessels). It is not recommended for use in children and adolescents under 18 years of age. It should be used with caution in pregnant and breastfeeding women. Do not consume alcohol as it may increase the risk of side-effects. Tunib 12.5 mg Capsule may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Tunib 12.5 mg Capsule

Treatment of Gastrointestinal stromal cancer, kidney cancer, and pancreatic neuroendocrine tumors.

Directions for Use

• Take Tunib 12.5 mg Capsule with or without food as advised by your doctor.• Typically, Tunib 12.5 mg Capsule is taken once daily for 28 days, followed by a 2-week break. This cycle is repeated every 6 weeks, as recommended by your doctor. However, always follow your doctor's instructions regarding dosage and duration.• Swallow the capsule as a whole with a glass of water.• Do not open, crush or dissolve Tunib 12.5 mg Capsule .

Medicinal Benefits

Tunib 12.5 mg Capsule is a targeted therapy used to treat advanced kidney cancer. It is also used in patients with kidney cancer to prevent recurrence after having kidney surgery. It is used to treat gastrointestinal stromal cancer that cannot be treated with imatinib, another anti-cancer medicine. It is used to manage pancreatic neuroendocrine tumors (cancer of hormone-producing cells of the pancreas) that cannot be treated with surgery. Tunib 12.5 mg Capsule can help to manage the above conditions if taken regularly as prescribed by the doctor.

How Tunib 12.5 mg Capsule Works

Tunib 12.5 mg Capsule contains sunitinib. It acts by slowing down the growth of cancer cells by two processes. It interferes with the action of a protein that promotes cell division and thereby decreases cancer cell production. It can inhibit a process called angiogenesis, the development of blood supply to the cancer cells. This effect inhibits the nutrient supply to the cancer cells, thereby causing cancer cell death eventually.

What if I have taken an overdose of Tunib 12.5 mg Capsule

Take Tunib 12.5 mg Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Tunib 12.5 mg Capsule may cause an increase in blood pressure. So, your doctor may monitor your blood pressure regularly and prescribe blood-pressure-lowering medicines if necessary. Tunib 12.5 mg Capsule may increase the risk of bleeding, and the risk is high if you are taking any blood thinners such as warfarin and acenocoumarol. Tunib 12.5 mg Capsule may cause heart problems, so notify your doctor if you experience extreme tiredness, shortness of breath, and swelling of the feet and ankles. Tunib 12.5 mg Capsule may cause heart rhythm abnormalities, so inform your doctor if you experience dizziness or abnormal heartbeats. Tunib 12.5 mg Capsule should be used with caution in patients with a recent history of blood clots, heart attack, or stroke as this medicine may cause chest pain, shortness of breath, difficulty speaking, weakness of one side of the body, or dizziness. Tunib 12.5 mg Capsule should be used with caution in patients with aneurysm (weakening of blood vessel wall), thrombotic microangiopathy (damage to the small blood vessels), and liver or kidney problems. Tunib 12.5 mg Capsule may cause inflammation of the pancreas or gallbladder and lead to symptoms such as abdominal pain (upper abdominal region), fever, and vomiting, in patients with a history of pancreatic or gallbladder disorders. Tunib 12.5 mg Capsule may cause thyroid gland problems, so inform your doctor if you experience frequent fatigue and extreme cold than others. Tunib 12.5 mg Capsule may cause skin ulceration (pyoderma gangrenosum) or infection (necrotizing fasciitis). So, inform your doctor if you notice symptoms of infection around a skin injury such as fever, pain, swelling, redness, and drainage of pus or blood from the wound. However, these effects are usually reversible after the discontinuation of therapy. If you develop severe skin rashes, especially with blistering or peeling of the skin, notify your doctor immediately as it can be a sign of a serious skin condition. Tunib 12.5 mg Capsule may cause headaches, high blood pressure, and vision problems in patients with a history of fits or seizures. While using Tunib 12.5 mg Capsule , blood sugar levels should be monitored regularly in patients with diabetes. In addition, notify your doctor immediately if you notice signs of low blood sugar such as fatigue, hunger, sweating, pounding heartbeat, and loss of consciousness.

Diet & Lifestyle Advise

  • Eat a healthy diet that includes fresh fruits and vegetables.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugars.
  • Maintain a healthy weight.
  • Avoid smoking and alcohol consumption.
  • Manage stress and use relaxation techniques such as meditation and yoga.
  • Get optimal sleep, rest well.
  • Limit exposure to environmental toxins such as smoke, asbestos, or other chemicals.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Tunib 12.5 mg Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Do not consume alcohol as it can increase the risk of side-effects.

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Pregnancy

Unsafe

Tunib 12.5 mg Capsule may cause harmful effects to the unborn baby when used in pregnant women. It is also advised to use reliable contraception to prevent pregnancy while using this medicine.

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Breast Feeding

Unsafe

Tunib 12.5 mg Capsule may cause harmful effects to the nursing baby when given to breastfeeding mothers. Consult your doctor before using Tunib 12.5 mg Capsule .

bannner image

Driving

Caution

Tunib 12.5 mg Capsule may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

bannner image

Liver

Caution

Tunib 12.5 mg Capsule should be used with caution in patients with liver diseases. The doctor may monitor liver function during the treatment.

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Kidney

Caution

Tunib 12.5 mg Capsule should be used with caution in patients with kidney diseases. The doctor may monitor kidney function during the treatment.

bannner image

Children

Unsafe

Tunib 12.5 mg Capsule is not recommended for children and adolescents below the age of 18 years.

Have a query?

FAQs

Tunib 12.5 mg Capsule is used to treat gastrointestinal stromal tumours (cancer of the stomach, bowel, or oesophagus), renal carcinoma (kidney cancer) and advanced pancreatic neuroendocrine tumours (cancer that has affected hormone-producing cells in the pancreas).

Tunib 12.5 mg Capsule contains sunitinib which is an anti-cancer medicine. It acts by slowing down the growth of cancer cells by two processes. It interferes with the action of a protein that promotes cell division and thereby decreases cancer cell production. It can inhibit a process called angiogenesis, the development of blood supply to the cancer cells. This effect inhibits the nutrient supply to the cancer cells, thereby causing cancer cell's death eventually.

Tunib 12.5 mg Capsule may cause thyroid dysfunction leading to decreasing in thyroid hormone levels. This effect cause hypothyroidism or underactive thyroid. So, notify your doctor if you feel extreme tiredness, colder than others, or change in voice while using this medicine.

Tunib 12.5 mg Capsule is not a cure for cancer. It can slow down cancer progression and prevent the spread of cancer cells to other parts of the body. Also, the effects of the medicine differ for each patient based on age and health history.

Tunib 12.5 mg Capsule can be taken as long as it is prescribed to you. The duration of the therapy is determined by the doctor based on your health condition.

Yes, Tunib 12.5 mg Capsule is considered chemotherapy. It is used to treat stomach cancer, advanced kidney cancer, and pancreatic neuroendocrine tumors (cancer of the pancreas's hormone-producing cells).

It is not known whether Tunib 12.5 mg Capsule can be taken with other chemotherapy medicines. So, please consult a doctor for advice.

Take Tunib 12.5 mg Capsule with or without food as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not chew or break it. Do not exceed the recommended dose.

Tunib 12.5 mg Capsule may make your skin lighter and may also cause hair loss. Other skin-related effects include dryness, thickening, cracking, blisters, or rashes, particularly on the palms and soles. These side effects are usually reversible and resolve once Tunib 12.5 mg Capsule is stopped. Tunib 12.5 mg Capsule may cause severe skin reactions, such as a serious rash or rapidly spreading skin ulcers, which could be life-threatening. Therefore, if you experience any of these side effects, please consult your doctor immediately.

Tunib 12.5 mg Capsule may cause serious liver problems, including potentially fatal complications. It is important to contact your doctor immediately if you notice symptoms such as itching, yellowing of the skin or eyes, dark urine, or pain in the upper right abdomen. To ensure your safety, your doctor will conduct blood tests to monitor liver function both before starting Tunib 12.5 mg Capsule and throughout the treatment.

No, generics are not available for Tunib 12.5 mg Capsule .

Tunib 12.5 mg Capsule may reduce blood sugar levels. So, diabetic patients should be cautious as it may cause very low blood sugar resulting in unconsciousness. Also, regularly monitor blood sugar levels. Consult your doctor immediately if you experience symptoms of low blood sugar, such as fatigue, palpitations, sweating, hunger, or loss of consciousness

Tunib 12.5 mg Capsule may increase blood pressure. Your doctor will monitor your blood pressure during treatment and may prescribe medicines to help control it if necessary.

Tunib 12.5 mg Capsule may cause side effects such as tiredness, pain, irritation, mouth sores, dry mouth, upset stomach, joint pain, back pain, abdominal pain, nausea, vomiting, loss of appetite, dryness of skin, cough, fever, and sleep difficulty. These do not require any medical treatment as they will gradually reduce over time. Consult, your doctor if these side effects persist longer.

Country of origin

India

Manufacturer/Marketer address

Ambala- Chandigarh Highway, Lalru €“ 140501, Punjab
Other Info - TUN0022

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:50 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.227.pdf

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