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Twinaqt 50/300 Tablet is used to treat HIV infection. It helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome). It contains Dolutegravir and Lamivudine, which work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, these help treat HIV infections. In some cases, this medication may cause side effects such as nausea, headache, tiredness, diarrhoea, dizziness, anxiety, gas, difficulty falling asleep or staying asleep, and muscle weakness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Twinaqt 50/300 Tablet

Twinaqt 50/300 Tablet belongs to a class of drugs called antiretrovirals used to treat HIV infection. Twinaqt 50/300 Tablet helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome). HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help fight infection, making the individual susceptible to other infections or illnesses.

Twinaqt 50/300 Tablet contains Dolutegravir and Lamivudine. Both Dolutegravir and Lamivudine are nucleoside reverse transcriptase inhibitors. Twinaqt 50/300 Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, Twinaqt 50/300 Tablet helps treat HIV infections.

Twinaqt 50/300 Tablet is a prescription medication. You should take this medicine exactly as prescribed by the doctor. The common side effects of Twinaqt 50/300 Tablet are nausea, headache, tiredness, diarrhoea, dizziness, anxiety, gas, difficulty falling asleep or staying asleep and muscle weakness. Most of these side effects of Twinaqt 50/300 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Twinaqt 50/300 Tablet is not recommended to take Twinaqt 50/300 Tablet if you are allergic to any of its contents. Twinaqt 50/300 Tablet is not recommended for use in children and adolescents under 18 years of age. Twinaqt 50/300 Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Consumption of alcohol may increase the risk of side effects; therefore, avoid alcohol consumption. You should not become pregnant while you are taking Twinaqt 50/300 Tablet . Talk to your doctor about effective birth control methods that you can use during your treatment. If you become pregnant while taking Twinaqt 50/300 Tablet , call your doctor immediately. You should not breastfeed if you are infected with HIV or if you are taking Twinaqt 50/300 Tablet .

Uses of Twinaqt 50/300 Tablet

Twinaqt 50/300 Tablet is used in the treatment of HIV (Human Immunodeficiency Virus) infection. The detailed uses of Twinaqt 50/300 Tablet are as follows:

  • Management of HIV infection: Twinaqt 50/300 Tablet helps reduce the amount of HIV in the body (viral load) and increases CD4 cell counts, helping maintain a stronger immune system.
  • Slows disease progression: Twinaqt 50/300 Tablet helps prevent the progression of HIV to AIDS and reduces the risk of HIV transmission.

Key Benefits

Twinaqt 50/300 Tablet is a combination of two drugs, Dolutegravir and Lamivudine, used to treat HIV infection. Both Dolutegravir and Lamivudine are nucleoside reverse transcriptase inhibitors. Twinaqt 50/300 Tablet interferes with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Thus, Twinaqt 50/300 Tablet helps treat HIV infections. Taking Twinaqt 50/300 Tablet along with practising safe sex and lifestyle changes may reduce the risk of getting or transmitting HIV to others.

Side effects of Twinaqt 50/300 Tablet

Directions for Use

  • Take Twinaqt 50/300 Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Twinaqt 50/300 Tablet Works

Twinaqt 50/300 Tablet contains Dolutegravir and Lamivudine. Both Dolutegravir and Lamivudine are nucleoside reverse transcriptase inhibitors. Twinaqt 50/300 Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, Twinaqt 50/300 Tablet helps treat HIV infections.
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Alcohol

Unsafe

Consumption of alcohol should be avoided.

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Pregnancy

Unsafe

Twinaqt 50/300 Tablet is not suggested during pregnancy. You should not become pregnant while you are taking Twinaqt 50/300 Tablet . Ask your doctor about effective birth control options that you can use during your therapy. If you become pregnant while taking Twinaqt 50/300 Tablet , call your doctor right away.

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Breast Feeding

Unsafe

You should not breastfeed if you are infected with HIV or if you are taking Twinaqt 50/300 Tablet .

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Driving

Caution

Twinaqt 50/300 Tablet may cause dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy after taking Twinaqt 50/300 Tablet .

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Liver

Caution

Take Twinaqt 50/300 Tablet with caution, especially if you have a history of liver diseases. Inform your doctor if you have liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Take Twinaqt 50/300 Tablet with caution, especially if you have a history of Kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Twinaqt 50/300 Tablet is not recommended for children below 18 years of age.

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Heart

Caution

Twinaqt 50/300 Tablet should be used with caution in heart patients and only under medical supervision. Though generally well tolerated, rare complications like lactic acidosis may indirectly affect heart function.

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Geriatrics

Safe if prescribed

Twinaqt 50/300 Tablet is generally safe for geriatric patients when prescribed and monitored by a doctor. Studies show good tolerance and effectiveness in older adults, though regular checkups are advised to watch for liver or kidney changes.

What if I have taken an overdose of Twinaqt 50/300 Tablet

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of Twinaqt 50/300 Tablet , go to the accident and emergency department of your local hospital at once. Do this even if there are no signs of discomfort or poisoning.

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis, as they can make you prone to HIV infection.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich foods such as dark green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.

Have a query?

How Soon It Starts Working

The time required for Twinaqt 50/300 Tablet to start to work: The time required for Twinaqt 50/300 Tablet to show its action is unknown. The time for which the effects of Twinaqt 50/300 Tablet last: The duration of action for Twinaqt 50/300 Tablet is unknown.

What if you forget to take Twinaqt 50/300 Tablet

If you miss a dose of Twinaqt 50/300 Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take an extra dose to make up for a missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep Twinaqt 50/300 Tablet out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Talk to your doctor about the risks and benefits of taking Twinaqt 50/300 Tablet . Before taking the Twinaqt 50/300 Tablet , inform your doctor about all your medical conditions, sensitivities, and medications you are using. Twinaqt 50/300 Tablet is not recommended for children below 18 years of age. You are advised to take proper precautions if you are infected with HIV to prevent infection from spreading to others through sexual contact or body fluids. If you have HBV and you take Twinaqt 50/300 Tablet , your condition may suddenly worsen when you stop taking Twinaqt 50/300 Tablet . Tell your doctor if you have or suspect you have hepatitis B virus infection (HBV; a continuous liver infection). Your doctor may test you to see if you have HBV before you start therapy with Twinaqt 50/300 Tablet . You are recommended to avoid alcohol consumption with Twinaqt 50/300 Tablet . Drive only if you are alert, as Twinaqt 50/300 Tablet may cause dizziness.

Drug-Drug Interactions

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Drug-Drug Interactions: Twinaqt 50/300 Tablet may interact with other antiviral medications (e.g. emtricitabine, tenofovir alafenamide), oral iron bivalent preparations (e.g. ferrous fumarate, ferrous sulfate), certain mineral supplements (zinc sulfate), anticancer medications (e.g. bexarotene, pexidartinib), HIV medications (e.g. emtricitabine, zalcitabine), and antirheumatic drugs (e.g. leflunomide).

Drug-Food Interactions: Twinaqt 50/300 Tablet may interact with alcohol and alcohol-containing beverages. Therefore, avoid alcohol intake and Twinaqt 50/300 Tablet as it may increase the risk of adverse effects.

Drug-Disease Interactions: Twinaqt 50/300 Tablet may interact with disease conditions, including hepatotoxicity (injury to the liver or impairment of the liver function), pancreatitis, renal dysfunction, or hemodialysis (a treatment to filter waste and water from your blood).

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Twinaqt 50/300 Tablet is used to treat HIV infection.

Twinaqt 50/300 Tablet contains Dolutegravir and Lamivudine. Twinaqt 50/300 Tablet works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes, which are necessary for the reproduction of the virus. Together, Twinaqt 50/300 Tablet helps treat HIV infections.

Twinaqt 50/300 Tablet does not cure HIV infection. Twinaqt 50/300 Tablet reduces the amount of HIV in the body and improves the immune system's functioning.

HIV infection may still be transmitted to other persons while using Twinaqt 50/300 Tablet . Twinaqt 50/300 Tablet reduces the risk of transmission, but still, HIV infection is contagious. Therefore, discuss with a doctor regarding precautions to avoid transmission of HIV while taking Twinaqt 50/300 Tablet .

Twinaqt 50/300 Tablet may increase the risk of treatment failure. So Twinaqt 50/300 Tablet should not be stopped without consulting your doctor.

Do not stop taking Twinaqt 50/300 Tablet without consulting your doctor. Stopping Twinaqt 50/300 Tablet before treatment may worsen your hepatitis. This can occur during the first few months after you stop taking Twinaqt 50/300 Tablet . Take the Twinaqt 50/300 Tablet strictly as instructed, and do not miss any dose.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - TWI0109
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