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  3. Uptofive Tablet

Uptofive Tablet, Pack of 1 Tablet
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Uptofive Tablet contains ulipristal which is used in the treatment of uterine fibroids (low dose) and for emergency contraception (high dose). This medicine works by stopping or delaying the release of an egg, thus helping as an emergency contraceptive. You may experience side effects like headaches, abdominal pain, nausea, dysmenorrhea, fatigue, and dizziness.
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Synonym :

ULIPRISTAL

Composition :

ULIPRISTAL ACETATE-30MG

Manufacturer/Marketer :

German Remedies Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Uptofive Tablet

Uptofive Tablet is indicated for the prevention of emergency pregnancy due to unprotected intercourse or a known or suspected contraceptive failure. Uptofive Tablet is not intended for routine use as a contraceptive. A lower dose of ulipristal acetate may be used to treat moderate to severe symptoms of uterine fibroids (also known as myomas), which are non-cancerous uterine tumours (womb).

Uptofive Tablet contains ulipristal acetate, which stops progesterone from working usually. Uptofive Tablet also works by stopping or delaying the release of an egg. Therefore, it helps as an emergency contraceptive.

Uptofive Tablet has to be taken within 120 hours (5 days) of sex to prevent pregnancy. It is not meant to be used as a primary method of contraception. However, you can use emergency contraception more than once throughout a menstrual cycle if necessary. You may experience headaches, abdominal pain, nausea, dysmenorrhea, fatigue, and dizziness. It may make your next period earlier, later or more painful than usual. The majority of Uptofive Tablet's side effects fade with time. However, if the adverse effects persist, consult your doctor.

Do not take Uptofive Tablet if you're allergic to ulipristal acetate or any ingredient present in Uptofive Tablet. Please seek medical advice before using Uptofive Tablet if you have severe asthma and severe liver disease. It is not recommended for use in pregnant women. If you are a nursing woman, you should not breastfeed for one week after taking this drug. In some cases, Uptofive Tablet may cause blurred vision, drowsiness or dizziness; if you experience these symptoms, do not drive or operate machines. You should avoid drinking grapefruit juice or eating grapefruit while on treatment with Uptofive Tablet. Uptofive Tablet is not suggested for individuals under the age of 18.

Uses of Uptofive Tablet

Used for emergency contraception and treatment of uterine fibroids.

Directions for Use

• Uptofive Tablet can be taken with or without food as advised by your doctor.• It is recommended to take once daily within 5 days of unprotected intercourse, or as advised by your doctor.• Swallow Uptofive Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Uptofive Tablet is primarily used as an emergency contraceptive to avoid unintended pregnancy. Uptofive Tablet contains ulipristal acetate, which stops progesterone from working usually. Uptofive Tablet also works by stopping or delaying the release of an egg. Therefore, it helps as an emergency contraceptive. The doctor may prescribe a lower dose of ulipristal acetate to treat moderate to severe symptoms of uterine fibroids (also known as myomas), which are non-cancerous uterine tumours (womb).

How Uptofive Tablet Works

Uptofive Tablet contains ulipristal acetate, which stops progesterone from working usually. Uptofive Tablet also works by stopping or delaying the release of an egg. Therefore, it helps as an emergency contraceptive.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Uptofive Tablet out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Uptofive Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Uptofive Tablet

Experience with ulipristal acetate overdose is limited. Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Uptofive Tablet if you're allergic to ulipristal acetate or any ingredient in Uptofive Tablet. Please seek medical advice before using Uptofive Tablet if you have severe asthma and severe liver disease. It is not recommended to use in pregnant women. If you are a nursing woman, you should not breastfeed for one week after taking this drug. Do not use this medication in more than the prescribed doses or longer duration. In some cases, Uptofive Tablet may cause blurred vision, drowsiness or dizziness; if you experience these symptoms, do not drive or operate machines. You should avoid eating grapefruit or drinking grapefruit juice while on treatment with Uptofive Tablet. Uptofive Tablet is not suggested for individuals under the age of 18.

Drug-Drug Interactions

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UlipristalGriseofulvin
Severe
UlipristalBosentan
Severe

Drug-Drug Interactions

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UlipristalGriseofulvin
Severe
How does the drug interact with Uptofive Tablet:
When taken together the blood levels of Uptofive Tablet may be significantly decreased by griseofulvin, which might impair the effectiveness of the medicine in treating the disease.

How to manage the interaction:
Although there is a possible interaction between Griseofulvin and Uptofive Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
UlipristalBosentan
Severe
How does the drug interact with Uptofive Tablet:
Bosentan can lower the levels of Uptofive Tablet in your blood, which could decrease its effectiveness in treating your condition.

How to manage the interaction:
Although using Bosentan and Uptofive Tablet together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting a doctor.
UlipristalColchicine
Severe
How does the drug interact with Uptofive Tablet:
Uptofive Tablet may raise colchicine levels in the blood to unsafe levels, raising the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Uptofive Tablet and Colchicine, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include stomach pain, diarrhea, fever, muscle pain, weakness or tiredness, and numbness. Do not discontinue any medications without consulting your doctor.
UlipristalOxcarbazepine
Severe
How does the drug interact with Uptofive Tablet:
Oxcarbazepine can drastically lower Uptofive Tablet levels in the blood, making the medicine less effective in treating illness.

How to manage the interaction:
Although taking oxcarbazepine with Uptofive Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
UlipristalNevirapine
Severe
How does the drug interact with Uptofive Tablet:
When Uptofive Tablet is taken with Nevirapine may reduce the blood levels of Uptofive Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Nevirapine and Uptofive Tablet together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting a doctor.
UlipristalEfavirenz
Severe
How does the drug interact with Uptofive Tablet:
When Efavirenz is taken with Uptofive Tablet, it can reduce the blood levels of Uptofive Tablet, which may make it less effective

How to manage the interaction:
Although there is a possible interaction between Efavirenz and Uptofive Tablet, you can take these medicines together if prescribed by your doctor. If you're having symptoms, it's important to let a doctor know. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Choose a diet high in whole grains, fruits and vegetables, and low-fat dairy products.

  • Include heart-healthy omega-3 fatty acid-containing foods and beverages in your daily diet.

  • Use low-fat cooking oils such as olive oil, canola oil, soybean oil and coconut oil.

  • Monitor your (BP) blood pressure daily, and if there is too much variation, contact your doctor right once.

  • A pregnancy test should be taken around a week after taking Uptofive Tablet.

  • Chronic stress and physical activity, such as jogging, should be avoided as they may increase vaginal bleeding.

  • Quitting smoking and abstaining from alcohol is the greatest way to reduce the risk of complications.

Habit Forming

No

Therapeutic Class

ORAL CONTRACEPTIVES
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Alcohol

Caution

It is unknown whether alcohol interacts with this drug. However, it is advised to avoid alcohol when taking this medicine as a precaution.

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Pregnancy

Unsafe

Uptofive Tablet is not recommended for use during pregnancy or suspected pregnancy. Please reach out to your doctor if you have any concerns.

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Breast Feeding

Caution

You shouldn't breastfeed for one week after taking this pill. Consult your doctor for further information.

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Driving

Caution

Uptofive Tablet may cause blurred vision, drowsiness or dizziness; if you experience these symptoms, do not drive or operate machines. Seek medical attention if the symptoms persist.

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Liver

Caution

Uptofive Tablet should be used with caution if you have severe liver disease. Please consult your doctor in case of any concerns.

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Kidney

Caution

No studies have been conducted to evaluate the effect of kidney disease on the disposition of Uptofive Tablet. Please consult your doctor in case of any concerns.

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Children

Unsafe

Uptofive Tablet is not recommended for children below the age of 18.

Have a query?

FAQs

Uptofive Tablet is indicated for the prevention of emergency pregnancy due to unprotected intercourse or a known or suspected contraceptive failure. A lower dose of ulipristal acetate may be used to treat moderate to severe symptoms of uterine fibroids (also known as myomas), which are non-cancerous uterine tumours (womb).

Uptofive Tablet contains ulipristal acetate, which stops progesterone from working usually. Uptofive Tablet also works by stopping or delaying the release of an egg. Thereby it helps as an emergency contraceptive.

Uptofive Tablet (tablet) is not indicated for regular birth control. It is only used as emergency contraception (within 120 hours) after unprotected sex or contraceptive failure.

Take another pill as soon as possible if you vomit within 3 hours after taking the Uptofive Tablet.

For emergency contraception, you can take Uptofive Tablet at any time of the day, before, during or after a meal. If you take this medication to treat or manage other medical conditions, you can take it as advised by the healthcare professional.

The doctor may prescribe a lower dose of ulipristal acetate (5mg) to treat moderate to severe symptoms of uterine fibroids (also known as myomas), which are non-cancerous uterine tumours (womb). However, please do not take it on your own to treat uterine fibroids.

There is no evidence that Uptofive Tablet has any effect on future fertility.

You can take Uptofive Tablet at any time in your menstruation cycle.

Uptofive Tablet may cause side effects like headaches, abdominal pain, nausea, dysmenorrhea, fatigue, and dizziness. If the side effects persist or worsen, consult your doctor.

A single dose of Uptofive Tablet may not stop periods. However, it might prepone or delay the period. Talk to the doctor if you have any concerns.

Uptofive Tablet should be swallowed as a whole with water; do not crush or chew it. For emergency contraception, Uptofive Tablet has to be taken within 120 hours (5 days) of sex to prevent pregnancy. For uterine fibroids, take it as advised by the doctor.

You may need to continue with regular birth control method to prevent pregnancy. However, consult the doctor if you have any concerns.

Take Uptofive Tablet as soon as possible, particularly within 120 hours (5 days) of having unprotected sex or experiencing contraceptive failure. Contact your doctor if you suffer significant vaginal bleeding after taking this medication. Consult your doctor if your periods are delayed by more than 7/10 days for a pregnancy test.

Country of origin

India

Manufacturer/Marketer address

Unimark Remedies Ltd. , 501/E-Wing,Skypark Chs Ltd,Oshiwara Garden Road, Next To Hdfc House, Off.S.V. Rpad, Goregaon (West), Mumbai- 400 104
Other Info - UP83838

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:24 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/022474s011lbl.pdf
  2. https://www.nhs.uk/conditions/contraception/emergency-contraception/
  3. https://www.medicines.org.uk/emc/files/pil.6657.pdf
  4. https://www.medicines.org.uk/emc/product/3951/smpc
  5. https://www.drugs.com/drug-interactions/ulipristal.html
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