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compositionComposition:NORFLOXACIN-400MG
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Prescription Medicine
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

NORFLOXACIN-400MG

Manufacturer/Marketer :

Cosme Healthcare

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Uriben 400mg Tablet

Uriben 400mg Tablet is an oral antibiotic prescribed to treat bacterial infections, primarily urinary tract infections (UTIs) and prostate infections. It works by stopping the growth of the bacteria causing the infection, helping to clear your symptoms and prevent the spread of the illness. This medicine is only effective against bacterial infections and will not work for viral infections like the common cold or flu.

To get the best results, you should take this medicine consistently at the same times each day as prescribed by your doctor. It is usually taken twice daily, either one hour before or two hours after a meal on an empty stomach. Drinking plenty of water throughout the day is highly recommended to help flush out your urinary tract and keep you well-hydrated.

While taking this medication, you may experience mild side effects such as nausea, dizziness, or heartburn. However, if you develop severe issues like persistent joint pain, tendon swelling, severe watery diarrhoea, or signs of an allergic reaction, stop taking the medicine and consult your doctor immediately.

Do not take this medicine if you have a history of tendon rupture or an allergy to similar antibiotics. Before starting, tell your doctor if you have kidney disease, muscle weakness disorders like myasthenia gravis, or a history of seizures.

This medicine can interact with multivitamins, antacids containing calcium or magnesium, and dairy products, which can lower its absorption and make it less effective. Elderly patients, pregnant women, and breastfeeding mothers should consult their doctor before using Uriben 400mg Tablet, as special precautions or alternative treatments may be needed.

Uses of Uriben 400mg Tablet

Uriben 400mg Tablet is used to treat bacterial infections, primarily urinary tract infections (UTIs) and prostate infections. The detailed uses of Uriben 400mg Tablet are as follows:

  • Urinary tract infections (UTIs): Uriben 400mg Tablet helps clear bacterial infections in the bladder and kidneys by stopping the bacteria from multiplying.
  • Prostate infections (prostatitis): It penetrates the prostate tissue to eliminate chronic or acute bacterial infections that cause painful urination.
  • Bacterial gastroenteritis: It treats severe stomach or intestinal infections caused by susceptible bacteria, helping to reduce diarrhoea and cramping.
     

Key Benefits

Uriben 400mg Tablet helps treat bacterial infections of the urinary tract and prostate by stopping the growth and spread of infection-causing bacteria. By addressing the underlying cause of the infection, it supports recovery and helps relieve uncomfortable urinary symptoms.

  • Helps Relieve Urinary Symptoms: As the infection begins to clear, symptoms such as burning during urination, urinary urgency, increased frequency of urination, and pelvic discomfort gradually improve, helping you feel more comfortable.
  • Supports Faster Recovery: By effectively controlling bacterial growth, Uriben 400mg Tablet helps your body recover from the infection and return to normal daily activities with less disruption.
  • Helps Prevent Infection-Related Complications: Timely treatment with Uriben 400mg Tablet can help prevent the infection from spreading to the kidneys or other areas of the body, reducing the risk of more serious health complications.
     
Side effects of Uriben 400mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

To ensure the medication works effectively, follow these instructions carefully:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • Take this medicine on an empty stomach, either 1 hour before or 2 hours after eating a meal or consuming dairy products.
  • Space your doses evenly throughout the day, exactly as prescribed by your healthcare provider.
  • Complete the entire course of treatment, even if you start to feel better after a few days. Stopping early may allow the infection to return or become resistant to antibiotics.
  • Always follow your doctor's exact instructions regarding how long and how often to take Uriben 400mg Tablet.
     

How Uriben 400mg Tablet Works

Uriben 400mg Tablet contains norfloxacin. Uriben 400mg Tablet works by targeting and blocking essential proteins that bacteria need to repair and copy their genetic material (DNA). Specifically, it inhibits enzymes known as DNA gyrase and topoisomerase IV inside the bacterial cells. Without these proteins, the bacteria cannot multiply, grow, or survive. This action rapidly reduces the number of active bacteria in your system, allowing your body's natural immune defence to clear the infection completely.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Uriben 400mg Tablet, as it may cause increased dizziness.

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Pregnancy

Caution

Uriben 400mg Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning to become pregnant. Your doctor will prescribe Uriben 400mg Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown if Uriben 400mg Tablet passes into breastmilk. Consult your doctor if you are breastfeeding before taking Uriben 400mg Tablet.

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Driving

Unsafe

Uriben 400mg Tablet may cause dizziness and light-headedness. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment/kidney disease.

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Children

Unsafe

Uriben 400mg Tablet is not recommended for children below 18 years, as its safety and effectiveness have not been established in this age group.

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Heart

Caution

Uriben 400mg Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Uriben 400mg Tablet.

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Geriatrics

Caution

Uriben 400mg Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Uriben 400mg Tablet

Do not take more than the prescribed dose of Uriben 400mg Tablet, as it may cause serious side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay highly hydrated: Drink 8 to 10 glasses of water daily to help flush bacteria out of your urinary tract and keep your kidneys functioning well.
  • Avoid dairy and calcium-rich foods close to your dose: Do not eat yoghurt, milk, cheese, or calcium-fortified juices within 2 hours of taking your medicine, as calcium blocks its absorption.
  • Protect your skin from the sun: This medication can make your skin highly sensitive to sunlight. Wear protective clothing and a wide-brimmed hat, and apply high-SPF sunscreen when outdoors. Avoid tanning beds.
  • Avoid caffeine: This medication can increase the effects of caffeine, leading to nervousness, sleeplessness, or a fast heartbeat. Limit your intake of coffee, tea, and energy drinks.
     

Have a query?

How Soon It Starts Working

The time required for Uriben 400mg Tablet to start to work: Uriben 400mg Tablet ideally shows its action within 3 to 4 hours after administration. The time for which the effects of Uriben 400mg Tablet last: The effect of Uriben 400mg Tablet lasts for 12 to 24 hours.

What if you forget to take Uriben 400mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose to make up for the missed dose.

Storage

Store Uriben 400mg Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the medication in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Tendon warning: Stop taking Uriben 400mg Tablet immediately and contact your doctor if you experience sudden pain, snapping, or swelling in any of your joints or tendons.
  • Avoid antacids and mineral supplements: Do not take antacids containing magnesium or aluminium, iron supplements, zinc, or multivitamins within 2 hours before or 2 hours after taking this medication.
  • Monitor for nerve sensations: Alert your healthcare provider immediately if you experience numbness, tingling, or a 'pins and needles' sensation in your extremities.
  • Do not share this medication: Even if someone else has similar symptoms, this antibiotic must only be taken under a doctor's supervision for a confirmed bacterial infection.
  • Watch for signs of yeast infection: Prolonged or repeated use of this antibiotic may cause oral thrush or a vaginal yeast infection. Consult your doctor if you notice white patches in your mouth or unusual discharge.
     

Drug-Drug Interactions

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Drug-Drug Interactions

  • Blood thinners (like warfarin): Uriben 400mg Tablet may increase the effects of blood thinners, raising the risk of bleeding.
  • Theophylline: This medicine can increase the levels of theophylline in your blood, which may lead to serious side effects like nausea, tremors, or seizures.
  • NSAIDs (like ibuprofen or naproxen): Taking these pain relievers alongside this antibiotic may increase the risk of central nervous system stimulation and seizures.
  • Cyclosporine: Combined use may increase the risk of kidney damage.


Drug-Food Interactions

  • Dairy products and calcium-fortified foods: Foods rich in calcium (like milk, yoghurt, and fortified orange juice) significantly lower the absorption of Uriben 400mg Tablet, making it less effective.
  • Caffeine: This medicine slows down how your body processes caffeine, which can cause increased heart rate, anxiety, and sleep issues.


Drug-Disease Interactions

  • Myasthenia gravis: This medication can worsen muscle weakness and breathing problems in individuals with this condition.
  • Kidney disease: Decreased kidney function can cause the medication to build up in your body, requiring a dose adjustment.
  • Seizure disorders: This medicine may lower the seizure threshold, making seizures more likely in patients with a history of epilepsy or brain injury.
  • Heart rhythm issues (QT prolongation): Use with caution if you have a history of prolonged QT interval or low potassium levels.
     
NorfloxacinMesoridazine
Critical
NorfloxacinBepridil
Critical

Drug-Drug Interactions

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NorfloxacinMesoridazine
Critical
How does the drug interact with Uriben 400mg Tablet:
Using Mesoridazine together with Uriben 400mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Uriben 400mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
NorfloxacinBepridil
Critical
How does the drug interact with Uriben 400mg Tablet:
Using bepridil together with Uriben 400mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Uriben 400mg Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Uriben 400mg Tablet:
Coadministration of Uriben 400mg Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Uriben 400mg Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Uriben 400mg Tablet:
Coadministration of Uriben 400mg Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Uriben 400mg Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Uriben 400mg Tablet:
The combination of Amiodarone and Uriben 400mg Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Uriben 400mg Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
How does the drug interact with Uriben 400mg Tablet:
Coadministration of Uriben 400mg Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Uriben 400mg Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Uriben 400mg Tablet:
Co-administration of Uriben 400mg Tablet with Glimepiride may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Glimepiride can be taken with Uriben 400mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Uriben 400mg Tablet:
Coadministration of Uriben 400mg Tablet with Tramadol may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Uriben 400mg Tablet with tramadol together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorfloxacinIopamidol
Severe
How does the drug interact with Uriben 400mg Tablet:
Coadministration of Uriben 400mg Tablet with Iopamidol may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although taking Uriben 400mg Tablet and Iopamidol together can cause an interaction, it can be taken if your doctor has suggested it. If you have seizures or a head injury, it's important to contact your doctor right away. Don't hesitate to reach out if you experience any of these symptoms. Do not stop using any medications without talking to a doctor.
How does the drug interact with Uriben 400mg Tablet:
Co-administration of Uriben 400mg Tablet with Dexamethasone can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
Taking Uriben 400mg Tablet with Dexamethasone together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu, Orange Juice

How to manage the interaction:
Consuming dairy products, cereal, or orange juice with Uriben 400mg Tablet can interfere with its absorption and reduce its levels in the blood and urinary tract. Using caffeine together with Uriben 400mg Tablet may increase the effects of caffeine. Uriben 400mg Tablet dose should be taken at least one hour before or two hours after consuming dairy products, cereal, or orange juice. Avoid taking caffeine with Uriben 400mg Tablet. Contact a doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Uriben 400mg Tablet is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections‚ prostatitis (prostate inflammation), and gonorrhoea (a sexually transmitted disease). Additionally, Uriben 400mg Tablet is used to treat infections of the stomach and intestine, such as traveller's diarrhoea.

Uriben 400mg Tablet contains Norfloxacin, which works by inhibiting the synthesis of an enzyme called DNA gyrase. Thereby, it kills the bacteria and treats bacterial infections.

Uriben 400mg Tablet may cause photosensitivity (sensitivity to sunlight) and increase your risk of sunburn. Avoid prolonged exposure to sunlight or tanning beds. Always wear protective clothing and sunscreen with an SPF of 30 or higher before going outdoors.

It is recommended to complete the course of Uriben 400mg Tablet, even if you feel better, as it is an antibiotic, and leaving it incomplete may lead to a more severe infection. To treat your condition effectually, continue taking Uriben 400mg Tablet for as long as your doctor has prescribed it.

Avoid consuming dairy products, such as milk and yoghurt, along with Uriben 400mg Tablet, as they may decrease the effectiveness of Uriben 400mg Tablet.

Do not take Uriben 400mg Tablet on your own, as self-medication may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections.

Maintain a minimum gap of two hours between Uriben 400mg Tablet and antacids, anti-ulcer medications (such as sucralfate), anti-HIV medications (like didanosine), and vitamin and mineral supplements. However, consult your doctor before taking other medicines with Uriben 400mg Tablet.

Consult your doctor before taking Uriben 400mg Tablet if you have diabetes, as Uriben 400mg Tablet may cause hypoglycaemia (low blood sugar levels). Regularly monitor blood sugar levels while taking Uriben 400mg Tablet to avoid hypoglycaemic events.

Uriben 400mg Tablet may cause changes in liver function tests and prothrombin time (time taken for blood clotting). Inform the person doing the tests that you are taking Uriben 400mg Tablet.

Common side effects of Uriben 400mg Tablet may include abdominal cramps, nausea, headache, and dizziness. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.

While alcohol does not directly stop Uriben 400mg Tablet from working, it is best to avoid it. Alcohol can cause dehydration and worsen side effects like dizziness, nausea, and stomach upset. Talk to your doctor for personalised advice.

Stop taking the medicine immediately, rest the affected area, and contact your doctor right away. This medication carries a risk of tendon inflammation or rupture, and prompt medical advice is essential. Talk to your doctor if you experience joint pain.

This medicine is generally not recommended during pregnancy or breastfeeding unless prescribed by a doctor who determines the benefits outweigh the risks. Talk to your doctor about safer alternative treatments.

Most patients begin to feel relief from symptoms like burning and urgency within 24 to 48 hours. However, you must finish the entire course prescribed by your doctor even if you feel completely better. Talk to your doctor if your symptoms do not improve after a few days.

You should not take antacids containing magnesium, aluminium, or calcium within 2 hours of taking your dose, as they will stop the antibiotic from absorbing. Talk to your doctor or pharmacist about safe ways to manage heartburn.

No, Uriben 400mg Tablet is an antibiotic and is only effective against bacterial infections. It will not work for viral infections like colds, flu, or bronchitis. Talk to your doctor to get an accurate diagnosis for your symptoms.

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Country of origin

India

Manufacturer/Marketer address

176, Industrial Business Park, Phase-1, Chandigarh
Other Info - UR43847
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