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compositionComposition:VALACYCLOVIR-500MG
prescription
Prescription Medicine
info
Valcosign 500 Tablet

Valcosign 500 Tablet is used to treat viral infections, including cold sores (an inflamed blister in or near the mouth), genital herpes (sexually transmitted infection marked by genital pain and sores), and herpes zoster (a viral infection that causes a painful rash). It contains valacyclovir, which stops the proliferation of viruses and treats viral infection. In some cases, this medicine may cause side effects like headache, dizziness, nausea, vomiting, diarrhoea, and sensitivity to sunlight.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VALACYCLOVIR-500MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Valcosign 500 Tablet

Valcosign 500 Tablet is used to treat viral infections. It plays a vital role in treating cold sores (an inflamed blister in or near the mouth caused by infection with the herpes simplex virus), genital herpes (a common sexually transmitted infection marked by genital pain and sores), and herpes zoster (a viral infection that causes a painful rash).

Valcosign 500 Tablet contains valacyclovir, which works by preventing the multiplication of viruses in human cells, stopping the proliferation of viruses and producing new viruses.

Sometimes, you may experience side effects like headaches, dizziness, feeling sick (nausea or vomiting), diarrhoea, and skin that is sensitive to sunlight. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not give Valcosign 500 Tablet if you are allergic to Valcosign 500 Tablet, valacyclovir, or any of its ingredients. Check with your doctor if you're pregnant, currently breastfeeding, or taking other prescribed or non-prescribed medicines. Use protection while having sexual intercourse to avoid the transfer of genital herpes (a sexually transmitted disease) to your partner.

Uses of Valcosign 500 Tablet

Valcosign 500 Tablet is an antiviral drug that is primarily used to treat herpesvirus infections. The detailed uses of Valcosign 500 Tablet are as follows:

  • Herpes Simplex Virus (HSV) Infections: It helps control oral and genital herpes by lowering symptoms and preventing new sores.
  • Shingles (Herpes Zoster): Used to cure shingles by shortening the duration and severity of the symptoms.
  • Chickenpox (Varicella): Sometimes given for chickenpox, particularly in people with weaker immune systems.
  • Recurrence Prevention: Used as suppressive therapy for people who experience recurring herpes outbreaks.

Key Benefits

  • Valcosign 500 Tablet contains Valacyclovir, which is an antiviral medication.
  • Valcosign 500 Tablet is used in treating viral infection by preventing the multiplication of viruses in human cells.
  • Valcosign 500 Tablet stops the proliferation of viruses and produces new viruses, slowing the clearing up of the viral infection.

Directions for Use

  • Valcosign 500 Tablet can be taken with or without food.
  • It is usually taken 2 times daily or as prescribed by your doctor.
  • Swallow Valcosign 500 Tablet as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Valcosign 500 Tablet Works

Valcosign 500 Tablet contains valacyclovir, which is an antiviral medication. Valcosign 500 Tablet is used in treating viral infection by preventing the multiplication of viruses in human cells. As a result, this stops the proliferation of viruses and produces new viruses, slowly leading to the viral infection clearing up.
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Alcohol

Caution

Alcohol is not known to cause any unpleasant side effects if taken along with Valcosign 500 Tablet. But intake of alcohol with Valcosign 500 Tablet may damage your liver. So intake of Valcosign 500 Tablet should be avoided with Valcosign 500 Tablet.

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Pregnancy

Consult your doctor

Valcosign 500 Tablet is a pregnancy Category B medicine. It is not known whether Valcosign 500 Tablet will affect pregnant women or fetus or not. Hence, the intake of Valcosign 500 Tablet should be only if prescribed and under medical supervision.

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Breast Feeding

Consult your doctor

Valcosign 500 Tablet is a pregnancy Category B medicine. It is not known whether Valcosign 500 Tablet will pass through the milk in breastfeeding women or not. Hence, Valcosign 500 Tablet should only be taken if prescribed by a doctor and under medical supervision.

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Driving

Unsafe

Valcosign 500 Tablet can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Caution

Valcosign 500 Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Valcosign 500 Tablet to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Valcosign 500 Tablet should not be given to children below the age of 12 years.

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Heart

Caution

Valcosign 500 Tablet should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Valcosign 500 Tablet.

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Geriatrics

Caution

Valcosign 500 Tablet should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Valcosign 500 Tablet.

What if I have taken an overdose of Valcosign 500 Tablet

Take Valcosign 500 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose, as it might cause an overdose. Symptoms of overdose may include extreme tiredness, loss of consciousness, mental/mood changes, seizures, and changes in the amount of urine. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Avoid alcoholic beverages with Valcosign 500 Tablet as they can make you dehydrated and may affect your sleep.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.
  • Include turmeric or yellow mustard in your diet to avoid constipation caused by antiviral drugs and increase the intake of fluids to stay hydrated.
  • Take enough vitamin D and fresh air as it is known to improve the symptoms of herpes infection.

Have a query?

How Soon It Starts Working

  • The time required for Valcosign 500 Tablet to start to work: Valcosign 500 Tablet ideally starts to show its action within 1 to 2 hours of administration. 
  • The time for which the effects of Valcosign 500 Tablet last: Valcosign 500 Tablet effect lasts for 12 to 24 hours.

What if you forget to take Valcosign 500 Tablet

If you miss a dose of Valcosign 500 Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Valcosign 500 Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Valcosign 500 Tablet if you are allergic to Valcosign 500 Tablet or its ingredients.
  • Inform your doctor about all other OTC medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
  • If you have kidney disease or a kidney transplant, a heart problem or a history of heart problems, have HIV/AIDS, are pregnant, or plan to become pregnant, Valcosign 500 Tablet should be taken with caution and only if a doctor prescribes it to you.
  • Valcosign 500 Tablet may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, especially when you start taking Valcosign 500 Tablet, so please get up gradually.
  • Also, do not drive a car or operate machinery that requires concentration, as Valcosign 500 Tablet may cause dizziness.
  • Please do not take Valcosign 500 Tablet if you have ever developed a rash due to a fever. Use protection while having sexual intercourse to avoid the transfer of genital herpes (a sexually transmitted disease) to your partner.
  • If you have a weakened immune system, please consult your doctor before taking Valcosign 500 Tablet, as a dose adjustment may be necessary.
  • Drinking plenty of fluid, as Valcosign 500 Tablet can cause dehydration and kidney damage.

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Drug-Drug interactions: Valcosign 500 Tablet may have an interaction with medication containing iodine, blood thinners (aspirin), NSAIDs (ibuprofen, naproxen), anti-biotics (amoxicillin), anti-allergy medications (cetirizine), beta-blockers (metoprolol), Vitamin B12, Cholecalciferol (vitamin D3).

Drug-Food Interactions: Valcosign 500 Tablet interacts with non-prescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Also, alcohol consumption and drinks containing caffeine should not be taken along with Valcosign 500 Tablet.

Drug-Disease Interactions: Inform your doctor if you have or had renal dysfunction or disease, hemodialysis (a procedure where a dialysis machine and a special filter called an artificial kidney, or a dialyzer, are used to clean your blood), and organ transplant, Immunodeficiency, bone marrow transplantation, and Neutropenia (lower-than-normal levels of neutrophils).

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Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

Valcosign 500 Tablet is used to treat viral infections. It plays a vital role in treating cold sores (an inflamed blister in or near the mouth caused by infection with the herpes simplex virus), genital herpes (A common sexually transmitted infection marked by genital pain and sores), and herpes zoster (a viral infection that causes a painful rash).
No, Valcosign 500 Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.
No, Valcosign 500 Tablet should not be taken if you have HIV (Human Immuno Deficiency Syndrome). It can increase the risk of Thrombotic Thrombocytopenic Purpura (blood clot formation in small blood vessels).
If you miss a dose of Valcosign 500 Tablet, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
No, Valcosign 500 Tablet does not cure herpes infection. Instead, it reduces pain and itching caused due to it and prevents a new sore formation.
Do not stop taking Valcosign 500 Tablet without talking to your doctor. If you suddenly stop taking Valcosign 500 Tablet, you may experience confusion, fever, mental state changes, or severe muscle stiffness. Your doctor will probably decrease your dose gradually depending upon your disease condition.
The side effects of Valcosign 500 Tablet include diarrhoea, headache, feeling dizzy, itching, rash, nausea or vomiting. If these side effects persist or worsen, please consult your doctor.
Take Valcosign 500 Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.
Take Valcosign 500 Tablet for as long as it is advised by your doctor. The dose and duration will depend on the cause of illness and your body reacts to the treatment. Follow your doctor's instructions and do not stop taking Valcosign 500 Tablet on your own.
Valcosign 500 Tablet is effective if the used in dose and for the exact duration as advised by your doctor. If you discontinue Valcosign 500 Tablet before completing the treatment, your symptoms may recur.
Valcosign 500 Tablet is not an antibiotic or a corticosteroid. It is an antiviral medicine and acts against viruses. It is effective against herpes simplex virus (cold sores, chickenpox, and genital herpes), cytomegalovirus (CMV) and varicella-zoster virus (shingles). Also, Valcosign 500 Tablet prevents the occurrence of CMV infection and disease after organ transplant.
Although Valcosign 500 Tablet reduces the chances of transmitting the infection to your partner, the possibility of transmission still exists. Therefore, you should practice safe sex by using condoms. However, if you have genital sores or blisters, you should not have sex.
Yes, Valcosign 500 Tablet can be given to children aged between 2 years to 18 years for chickenpox. For best results, the treatment should begin within 24 hours of the appearance of the rash. Valcosign 500 Tablet should be given for 5 days and as advised by the doctor.
If you accidentally take excess of Valcosign 500 Tablet, contact your doctor or go to a nearby hospital immediately. The symptoms of Valcosign 500 Tablet overdose include confusion, feeling sick (nausea), vomiting, hallucinations, agitation, decreased consciousness, and coma.
Your doctor will recommend a low dose of Valcosign 500 Tablet since you are elderly and have a kidney problem. During the day, you must drink plenty of water regularly while taking Valcosign 500 Tablet to reduce the side effects which can affect the kidney or nervous system. Your doctor will closely monitor you for signs of any side effects such as feeling confused, agitated or unusually sleepy, or drowsy. If you experience any of these effects, contact your doctor immediately.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 020487S007Rel2 Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Valacyclovir Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Valacyclovir Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. Drugs.com Clinical Review Team. Valacyclovir Pregnancy and Lactation Reference Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  5. Valacyclovir hydrochloride. 1995. [Accessed on 19 Jun. 2019] Check here
  6. Valaciclovir hydrochloride. 2011. [Accessed on 24 Jan. 2019] Check here
  7. CiplaMed CiplaMed. 2022. [Accessed on 20 Feb. 2024]Check here

Country of origin

India
Other Info - VA92206
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