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  3. Virem 600mg Tablet 60's

Virem 600mg Tablet 60's, Pack of 1 TABLET
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Virem 600mg Tablet belongs to the class of antiretroviral drugs used in the treatment of HIV infection. This medicine works by inhibiting a protein called protease, which is required by virus-infected cells to generate new viruses. Common side effects include dizziness, headache, diarrhoea, nausea, vomiting, rashes, and feeling weak.
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Composition :

DARUNAVIR-600MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Virem 600mg Tablet

Virem 600mg Tablet belongs to a class of antiretroviral drugs called protease inhibitors primarily used to treat HIV (Human Immunodeficiency Virus) infection in adults and children aged 3 years and above weighing at least 15kg. HIV is a virus that targets the immune system, primarily white blood cells. HIV destroys white blood cells and reduces a person's resistance to infections.

Virem 600mg Tablet contains Darunavir that works by inhibiting a protein called protease, which is required by virus-infected cells to generate new viruses. As a result, Virem 600mg Tablet reduces the amount of HIV in the body. Thereby, helps improve the immune system and lowers the risk of developing any illness related to HIV infection.

Take Virem 600mg Tablet with food. Your doctor will decide the dose and duration based on your medical condition. In some cases, Virem 600mg Tablet may cause certain common side effects such as headache, nausea, dizziness, abdominal pain, diarrhoea, and vomiting. Most of these side effects do not necessitate medical treatment and fade away with time. Please check with your doctor if the side effects persist or worsen.

Consult your doctor before taking Virem 600mg Tablet if you are pregnant. Due to the risk of HIV transmission, women infected with HIV are recommended not to breastfeed. Virem 600mg Tablet may cause dizziness, so drive only if you are alert. Virem 600mg Tablet should not be given to children below 3 years of age or weighing below 15kg as safety and effectiveness have not been established. Avoid or limit alcohol consumption as it may cause increased dizziness. Keep your doctor updated about your health condition and medications to rule out any interactions.

Uses of Virem 600mg Tablet

Virem 600mg Tablet is used in the treatment of HIV (human immunodeficiency virus) infection. The detailed use of Virem 600mg Tablet is as follows:<br/>• Treatment of HIV-1 infection: Virem 600mg Tablet is used in the treatment of HIV-1 infection in adults and children and also part of a combination antiretroviral therapy (ART) regimen.<br/>

Directions for Use

• Virem 600mg Tablet should be taken with food, or as a doctor advises. • It is usually taken once or twice a day. However, follow your doctor's instructions regarding dosage and timing for optimal results. • Swallow Virem 600mg Tablet as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

Virem 600mg Tablet falls under the category of antiretroviral agents. It is primarily used to treat HIV (Human Immunodeficiency Virus) infection in adults and children aged 3 years and above weighing at least 15kg. Virem 600mg Tablet works by inhibiting a protein enzyme called protease, which is required by virus-infected cells to generate new viruses. As a result, Virem 600mg Tablet reduces the amount of HIV in the body. Thereby, helps improve the immune system and lowers the risk of developing any illness related to HIV infection.

How Virem 600mg Tablet Works

Virem 600mg Tablet contains Darunavir that works by inhibiting a protein called protease, which is required by virus-infected cells to generate new viruses. As a result, Virem 600mg Tablet reduces the amount of HIV in the body. Thereby, helps improve the immune system and lowers the risk of developing any illness related to HIV infection.

Storage

• Store in a cool and dry place away from sunlight. • Keep Virem 600mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Virem 600mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Virem 600mg Tablet

Never take more than the prescribed dose. Overdose of Virem 600mg Tablet may cause increased side effects. If you suspect that you might have taken an overdose of Virem 600mg Tablet , seek emergency medical help.

Drug Warnings

Please do not take Virem 600mg Tablet if you are allergic to any of its constituents or if you have severe liver problems. Inform your doctor if you have diabetes, infections, haemophilia, musculoskeletal problems, rash, kidney or liver impairment. Consult your doctor before taking Virem 600mg Tablet if you are pregnant. Due to the risk of HIV transmission, women infected with HIV are recommended not to breastfeed. Virem 600mg Tablet may cause dizziness, so drive only if you are alert. Virem 600mg Tablet should not be given to children below 3 years of age or weighing below 15kg as safety and effectiveness have not been established. Avoid or limit alcohol consumption as it may cause increased dizziness. While taking this medication, you can still pass on HIV, though the risk is reduced by effective antiretroviral therapy. Discuss with your doctor the precautions you should take to avoid infecting others. Talk to your doctor immediately if you notice any signs or symptoms of infection or inflammation. Keep your doctor updated on your health condition and medications to rule out any negative effects or adverse events.

Drug-Drug Interactions

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DarunavirSimvastatin
Critical
DarunavirRifampicin
Critical

Drug-Drug Interactions

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DarunavirSimvastatin
Critical
How does the drug interact with Virem 600mg Tablet:
Combining Virem 600mg Tablet and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Virem 600mg Tablet and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
DarunavirRifampicin
Critical
How does the drug interact with Virem 600mg Tablet:
Taking Virem 600mg Tablet with rifampicin can decrease the blood levels of Virem 600mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Virem 600mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DarunavirSildenafil
Critical
How does the drug interact with Virem 600mg Tablet:
Combining Virem 600mg Tablet and Sildenafil can increase the blood levels and effects of Sildenafil.

How to manage the interaction:
Taking Virem 600mg Tablet and Sildenafil together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DarunavirColchicine
Critical
How does the drug interact with Virem 600mg Tablet:
Coadministration of colchicine with Virem 600mg Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicine with Virem 600mg Tablet is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
DarunavirLurasidone
Critical
How does the drug interact with Virem 600mg Tablet:
Using Lurasidone together with Virem 600mg Tablet may result in significantly higher Lurasidone blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurasidone and Virem 600mg Tablet may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
DarunavirEverolimus
Severe
How does the drug interact with Virem 600mg Tablet:
Taking Everolimus with Virem 600mg Tablet can considerably raise blood levels of everolimus, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although there is a possible interaction between Virem 600mg Tablet and Everolimus, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
DarunavirPhenytoin
Severe
How does the drug interact with Virem 600mg Tablet:
Coadministration of Phenytoin and Virem 600mg Tablet may decrease the blood levels of Virem 600mg Tablet, which may make Virem 600mg Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Virem 600mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
DarunavirCarbamazepine
Severe
How does the drug interact with Virem 600mg Tablet:
Using carbamazepine and Virem 600mg Tablet together may cause Virem 600mg Tablet to be less effective.

How to manage the interaction:
Although taking carbamazepine and Virem 600mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DarunavirRosuvastatin
Severe
How does the drug interact with Virem 600mg Tablet:
Co-administration of Rosuvastatin and Virem 600mg Tablet can increase the blood levels of rosuvastatin and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Rosuvastatin and Virem 600mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
DarunavirBromocriptine
Severe
How does the drug interact with Virem 600mg Tablet:
When Bromocriptine is taken with Virem 600mg Tablet, the amount of Bromocriptine in the blood can increase.

How to manage the interaction:
There may be a possibility of interaction between Virem 600mg Tablet and Bromocriptine, but it can be taken if prescribed by a doctor. Consult your doctor immediately if you have any symptoms - headache, dizziness, sleepiness, or lightheadedness. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take care of your mental health. Fear and anxiety can hamper the immune system as well. Therapy, yoga, and meditation effectively provide peace of mind.
  • Spending time with family or doing whatever makes you happy might help minimise emotional and physical stress.
  • Never exchange personal objects that have been contaminated with bodily fluids or blood, such as razor blades or toothbrushes.
  • Never share used needles, other injection or drug equipment as it may spread viruses.
  • Use condoms for safe sex; it helps to reduce contact with sperm and vaginal fluids.
  • Other sexually transmitted infections, such as gonorrhoea or syphilis, can make you more susceptible to HIV infection.
  • Consume a well-balanced diet. Include vitamin and nutrient-rich foods like dark-green, yellow, orange, red vegetables and fruits to enhance your immune system. Choose lean protein and whole carbohydrates over-processed foods.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Virem 600mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is unknown whether consuming alcohol with Virem 600mg Tablet is safe. However, it is best to avoid or limit alcohol consumption as a precaution.

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Pregnancy

Caution

If you are pregnant or planning for pregnancy, please seek medical advice. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Breastfeeding should be avoided by HIV-infected mothers due to the risk of HIV transmission.

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Driving

Caution

Virem 600mg Tablet may cause dizziness and drowsiness. Drive or operate heavy machinery only if you are alert.

bannner image

Liver

Caution

Please consult your doctor if you have liver problems. Avoid taking Virem 600mg Tablet if you have severe liver impairment.

bannner image

Kidney

Caution

Limited data is available regarding the usage of Virem 600mg Tablet in patients with kidney impairment, therefore, please consult your doctor if you have any concerns.

bannner image

Children

Caution

Virem 600mg Tablet is not recommended for children younger than 3 years of age or weighing below 15kg.

Have a query?

FAQs

Virem 600mg Tablet belongs to a class of antiretroviral drugs called protease inhibitors primarily used to treat HIV (Human Immunodeficiency Virus) infection in adults and children aged 3 years and above weighing at least 15kg.

Virem 600mg Tablet works by inhibiting protease enzyme that is essential for the reproduction of the human immunodeficiency virus. Thereby, it prevents the production of the new human immunodeficiency virus. Thus, Virem 600mg Tablet lowers virus load in the body and helps treat the infection.

Some patients taking antiretroviral combination therapy may develop osteonecrosis (death of bone tissue due to loss of blood supply to the bone). If you experience joint ache, pain, stiffness, or difficulty movement, consult your doctor.

In some cases, Virem 600mg Tablet may cause a rash, especially when used in combination with raltegravir. A rash is generally mild to moderate. However, occasionally it may become severe. Please inform your doctor if you develop a rash.

Virem 600mg Tablet might increase sugar levels in the blood, therefore, consult your doctor before taking Virem 600mg Tablet if you are diabetic. You are advised to monitor your blood glucose levels regularly while taking Virem 600mg Tablet .

Do not stop taking Virem 600mg Tablet without consulting your doctor as it may reduce the effectiveness of anti-HIV therapy. Continue taking Virem 600mg Tablet for as long as your doctor has prescribed it to you to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Virem 600mg Tablet .

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - VIR0061

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 6:27 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.11193.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/021976Orig1s063lbl.pdf
  3. https://www.ncbi.nlm.nih.gov/books/NBK501542/

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