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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
VORAZE 200MG VIAL injection is used to treat a broad range of fungal infections. It contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized. Common side effects of VORAZE 200MG VIAL injection are injection site reactions, peripheral oedema, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, anxiety, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, irregular heartbeats, low blood pressure, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills.
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Whats That

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Composition :

VORICONAZOLE-200MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About VORAZE 200MG VIAL injection

VORAZE 200MG VIAL injection belongs to the class of medicines known as 'antifungals' used to treat a broad range of fungal infections. A fungal infection is caused when a fungus invades and affects any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area and blood.

VORAZE 200MG VIAL injection contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

VORAZE 200MG VIAL injection will be administered by a qualified healthcare professional. In some cases, you may experience certain common side effects, such as injection site reactions, peripheral oedema, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, anxiety, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, irregular heartbeats, low blood pressure, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking VORAZE 200MG VIAL injection, let your doctor know about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. VORAZE 200MG VIAL injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Uses of VORAZE 200MG VIAL injection

Treatment of Fungal infections

Directions for Use

• Your doctor will determine the dosage and frequency depending on your condition.• VORAZE 200MG VIAL injection will be administered by a healthcare professional.• Do not self-administer.

Medicinal Benefits

VORAZE 200MG VIAL injection belongs to the class of medicines known as 'antifungal agents', used to treat a broad range of fungal infections, including aspergillosis (a disease caused by Aspergillus), candidiasis (fungal infection caused by yeast), coccidioidomycosis (an infection caused by the fungus Coccidioides), histoplasmosis (an infection caused by a fungus called Histoplasma), and penicilliosis (a disease caused by the fungus Talaromyces marneffei). It also effectively treats CNS fungal infections transmitted by epidural injection of contaminated steroids. On the other hand, it can prevent fungal infections in people undergoing bone marrow transplants. VORAZE 200MG VIAL injection works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

How VORAZE 200MG VIAL injection Works

VORAZE 200MG VIAL injection contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Storage

• Store in a cool and dry place away from sunlight.
• Keep VORAZE 200MG VIAL injection out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of VORAZE 200MG VIAL injection
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of VORAZE 200MG VIAL injection

As VORAZE 200MG VIAL injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Inform your doctor about your medical conditions, sensitivities, and medications you are using. And also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding. Women of childbearing potential should always use effective contraception during treatment. Please inform your doctor if you are suffering from a heart problem like an irregular heartbeat, slow heart rate or abnormality in ECG (electrocardiogram), QT prolongation, or if you have hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption. VORAZE 200MG VIAL injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Drug-Drug Interactions

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VoriconazoleErgometrine
Critical

Drug-Drug Interactions

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How does the drug interact with VORAZE 200MG VIAL injection:
Taking VORAZE 200MG VIAL injection with Rifampicin can increase blood level of VORAZE 200MG VIAL injection.

How to manage the interaction:
Although there is an interaction between VORAZE 200MG VIAL injection with Rifampicin, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VoriconazoleErgometrine
Critical
How does the drug interact with VORAZE 200MG VIAL injection:
The concentration of Ergometrine can be increased when it is combined with VORAZE 200MG VIAL injection.

How to manage the interaction:
Taking Ergometrine with VORAZE 200MG VIAL injection is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
When VORAZE 200MG VIAL injection is taken with Rifabutin, the amount of VORAZE 200MG VIAL injection in the blood may decrease.

How to manage the interaction:
Taking Rifabutin with VORAZE 200MG VIAL injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Coadministration of VORAZE 200MG VIAL injection with Efavirenz can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking VORAZE 200MG VIAL injection with Efavirenz can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Taking VORAZE 200MG VIAL injection and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects (liver damage and rhabdomyolysis - involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking VORAZE 200MG VIAL injection and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if a doctor advises. However, if you experience muscle pain, fever or dark-colored urine, vomiting, and yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Using Cisapride together with VORAZE 200MG VIAL injection may significantly increase the blood levels and effects of cisapride.

How to manage the interaction:
Taking VORAZE 200MG VIAL injection with Cisapride is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Using Nimodipine together with VORAZE 200MG VIAL injection may significantly increase the risk of serous side effects.

How to manage the interaction:
Taking Nimodipine with VORAZE 200MG VIAL injection is not recommended, as it may lead to an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Co-administration of Silodosin together with VORAZE 200MG VIAL injection, may significantly increase the blood levels and effects of Silodosin which may lead to side effects.

How to manage the interaction:
Taking VORAZE 200MG VIAL injection and Silodosin is not recommended, but it can be taken if prescribed by a doctor. If you experience dizziness, headache, heart palpitation-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with VORAZE 200MG VIAL injection:
Taking VORAZE 200MG VIAL injection together with primidone may reduce the blood levels of VORAZE 200MG VIAL injection, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between VORAZE 200MG VIAL injection and Primidone, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Using VORAZE 200MG VIAL injection together with Carbamazepine may significantly reduce the blood levels of VORAZE 200MG VIAL injection.

How to manage the interaction:
Taking Carbamazepine with VORAZE 200MG VIAL injection is not recommended, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • In wet places such as changing rooms and gym showers, don’t walk barefoot to prevent fungal infections.
  • Do not scratch the affected skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.
  • It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS
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Alcohol

Consult your doctor

It is not known if alcohol affects VORAZE 200MG VIAL injection. Please consult your doctor.

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Pregnancy

Caution

VORAZE 200MG VIAL injection is generally not recommended in pregnancy. Your doctor may prescribe this medicine if the benefit to the mother outweighs the potential risk to the fetus.

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Breast Feeding

Caution

If you are breastfeeding, please inform your doctor. It is not known if VORAZE 200MG VIAL injection passes into breastmilk. Your doctor may advise you to stop breastfeeding before starting the treatment with VORAZE 200MG VIAL injection.

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Driving

Unsafe

VORAZE 200MG VIAL injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

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Liver

Caution

Inform your doctor if you have liver problems before receiving VORAZE 200MG VIAL injection.

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Kidney

Caution

Inform your doctor if you have kidney problems before receiving VORAZE 200MG VIAL injection.

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Children

Caution

Your doctor may prescribe this medicine if the benefits outweigh the risks.

Have a query?

FAQs

VORAZE 200MG VIAL injection is used to treat Fungal infections.

VORAZE 200MG VIAL injection contains Voriconazole that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

VORAZE 200MG VIAL injection can also prevent fungal infections in people undergoing bone marrow transplants.

VORAZE 200MG VIAL injection may not be suitable in patients with known hypersensitivity to any of the components present in VORAZE 200MG VIAL injection; or with a hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption.

You can take VORAZE 200MG VIAL injection with contraceptive pills. However, some studies show a chance of an increase in the body's hormonal levels when you take VORAZE 200MG VIAL injection with a combined pill. Seek your doctor's advice if any side effects occur.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person, as it can also spread the infection.

VORAZE 200MG VIAL injection can use women of childbearing potential; however, they must always use effective contraception during treatment.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - VOR0010

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