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  3. Vorifucel 200mg Injection

Vorifucel 200mg Injection, Pack of 1 Injection
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Vorifucel 200mg Injection is used to treat a broad range of fungal infections. It contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized. Common side effects of Vorifucel 200mg Injection are injection site reactions, peripheral oedema, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, anxiety, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, irregular heartbeats, low blood pressure, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills.
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Composition :

VORICONAZOLE-200MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Vorifucel 200mg Injection

Vorifucel 200mg Injection belongs to the class of medicines known as 'antifungals' used to treat a broad range of fungal infections. A fungal infection is caused when a fungus invades and affects any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area and blood.

Vorifucel 200mg Injection contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Vorifucel 200mg Injection will be administered by a qualified healthcare professional. In some cases, you may experience certain common side effects, such as injection site reactions, peripheral oedema, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, anxiety, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, irregular heartbeats, low blood pressure, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Vorifucel 200mg Injection, let your doctor know about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Vorifucel 200mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Uses of Vorifucel 200mg Injection

Treatment of Fungal infections

Directions for Use

Vorifucel 200mg Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Vorifucel 200mg Injection belongs to the class of medicines known as 'antifungal agents', used to treat a broad range of fungal infections, including aspergillosis (a disease caused by Aspergillus), candidiasis (fungal infection caused by yeast), coccidioidomycosis (an infection caused by the fungus Coccidioides), histoplasmosis (an infection caused by a fungus called Histoplasma), and penicilliosis (a disease caused by the fungus Talaromyces marneffei). It also effectively treats CNS fungal infections transmitted by epidural injection of contaminated steroids. On the other hand, it can prevent fungal infections in people undergoing bone marrow transplants. Vorifucel 200mg Injection works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

How Vorifucel 200mg Injection Works

Vorifucel 200mg Injection contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Storage

Store in a cool and dry place away from sunlight
Side effects of Vorifucel 200mg Injection
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat more potassium-rich foods, like bananas, leafy greens, sweet potatoes, avocados, and nuts/seeds.
  • Choose potassium-fortified foods such as orange juice and sports beverages.
  • Limit potassium-depleting foods like caffeine, processed foods, and sugary drinks.
  • Exercise regularly, like walking or yoga, to help maintain potassium balance.
  • Inform your doctor if hypokalemia doesn't improve or worsen despite treatment.

What if I have taken an overdose of Vorifucel 200mg Injection

As Vorifucel 200mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Inform your doctor about your medical conditions, sensitivities, and medications you are using. And also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding. Women of childbearing potential should always use effective contraception during treatment. Please inform your doctor if you are suffering from a heart problem like an irregular heartbeat, slow heart rate or abnormality in ECG (electrocardiogram), QT prolongation, or if you have hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption. Vorifucel 200mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Drug-Drug Interactions

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VoriconazolePhenobarbital
Critical
VoriconazoleCisapride
Critical

Drug-Drug Interactions

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VoriconazolePhenobarbital
Critical
How does the drug interact with Vorifucel 200mg Injection:
Using Vorifucel 200mg Injection together with Phenobarbital may significantly reduce the blood levels of Vorifucel 200mg Injection.

How to manage the interaction:
Taking Vorifucel 200mg Injection with Phenobarbital is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
VoriconazoleCisapride
Critical
How does the drug interact with Vorifucel 200mg Injection:
Using Cisapride together with Vorifucel 200mg Injection may significantly increase the blood levels and effects of cisapride.

How to manage the interaction:
Taking Vorifucel 200mg Injection with Cisapride is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
VoriconazoleLurasidone
Critical
How does the drug interact with Vorifucel 200mg Injection:
Using Lurasidone together with Vorifucel 200mg Injection may result in significantly higher Lurasidone blood levels.

How to manage the interaction:
While Lurasidone and Vorifucel 200mg Injection may interact, it is not recommended that they be used unless prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, dizziness, headache, or heart palpitations. Do not discontinue any medications without consulting a doctor.
VoriconazolePrimidone
Critical
How does the drug interact with Vorifucel 200mg Injection:
Taking Vorifucel 200mg Injection together with primidone may reduce the blood levels of Vorifucel 200mg Injection, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Vorifucel 200mg Injection and Primidone, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
VoriconazoleMesoridazine
Critical
How does the drug interact with Vorifucel 200mg Injection:
Using Mesoridazine together with Vorifucel 200mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Vorifucel 200mg Injection is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
VoriconazoleRifampicin
Critical
How does the drug interact with Vorifucel 200mg Injection:
Taking Vorifucel 200mg Injection with Rifampicin can increase blood level of Vorifucel 200mg Injection.

How to manage the interaction:
Although there is an interaction between Vorifucel 200mg Injection with Rifampicin, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VoriconazoleIvabradine
Critical
How does the drug interact with Vorifucel 200mg Injection:
Using ivabradine together with Vorifucel 200mg Injection may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Vorifucel 200mg Injection together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
VoriconazoleNimodipine
Critical
How does the drug interact with Vorifucel 200mg Injection:
Using Nimodipine together with Vorifucel 200mg Injection may significantly increase the risk of serous side effects.

How to manage the interaction:
Taking Nimodipine with Vorifucel 200mg Injection is not recommended, as it may lead to an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medication without consulting a doctor.
VoriconazoleTolvaptan
Critical
How does the drug interact with Vorifucel 200mg Injection:
Co-administration of Tolvaptan together with Vorifucel 200mg Injection may significantly increase the blood levels and effects of Tolvaptan.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Vorifucel 200mg Injection, but it can be taken if prescribed by a doctor. If you experience difficulty swallowing, trouble speaking, muscle weakness call a doctor right away. Do not stop using any medications without a doctor's advice.
VoriconazoleAlfuzosin
Critical
How does the drug interact with Vorifucel 200mg Injection:
Using alfuzosin together with Vorifucel 200mg Injection may significantly increase the blood levels and effects of alfuzosin.

How to manage the interaction:
Taking Vorifucel 200mg Injection with Alfuzosin is not recommended, please consult a doctor before taking it. Call a doctor if you experience dizziness, headache, nasal congestion, or heart palpitation. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • In wet places such as changing rooms and gym showers, don’t walk barefoot to prevent fungal infections.
  • Do not scratch the affected skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.
  • It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Vorifucel 200mg Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is not known if alcohol affects Vorifucel 200mg Injection. Please consult your doctor.

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Pregnancy

Caution

Vorifucel 200mg Injection is generally not recommended in pregnancy. Your doctor may prescribe this medicine if the benefit to the mother outweighs the potential risk to the fetus.

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Breast Feeding

Caution

If you are breastfeeding, please inform your doctor. It is not known if Vorifucel 200mg Injection passes into breastmilk. Your doctor may advise you to stop breastfeeding before starting the treatment with Vorifucel 200mg Injection.

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Driving

Unsafe

Vorifucel 200mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

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Liver

Caution

Inform your doctor if you have liver problems before receiving Vorifucel 200mg Injection.

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Kidney

Caution

Inform your doctor if you have kidney problems before receiving Vorifucel 200mg Injection.

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Children

Caution

Your doctor may prescribe this medicine if the benefits outweigh the risks.

Have a query?

FAQs

Vorifucel 200mg Injection is used to treat Fungal infections.

Vorifucel 200mg Injection contains Voriconazole that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Vorifucel 200mg Injection can also prevent fungal infections in people undergoing bone marrow transplants.

Vorifucel 200mg Injection may not be suitable in patients with known hypersensitivity to any of the components present in Vorifucel 200mg Injection; or with a hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption.

You can take Vorifucel 200mg Injection with contraceptive pills. However, some studies show a chance of an increase in the body's hormonal levels when you take Vorifucel 200mg Injection with a combined pill. Seek your doctor's advice if any side effects occur.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person, as it can also spread the infection.

Vorifucel 200mg Injection can use women of childbearing potential; however, they must always use effective contraception during treatment.

Country of origin

India
Other Info - VO87396

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jan 1, 2025 | 2:45 PM IST

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Reference

  1. https://labeling.pfizer.com/ShowLabeling.aspx?id=12292
  2. https://www.ikrispharmanetwork.com/voriconazole-200mg/
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