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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Vpl 5 mg Injection 10 x 2 ml is used to treat abnormal heart rhythms (arrhythmia), such as an irregular or rapid heart rate. It can also treat high blood pressure (hypertension) and heart failure. It contains Verapamil. It works by relaxing the blood vessels, decreasing the workload on the heart. It also increases the blood and oxygen supply to the heart, normalizing electrical impulses. These effects help reduce blood pressure and control the rate and rhythm of the heartbeat.
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Whats That

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Synonym :

VERAPAMIL HYDROCHLORIDE

Composition :

VERAPAMIL-5MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Vpl 5 mg Injection 10 x 2 ml

Vpl 5 mg Injection 10 x 2 ml belongs to the class of medications called calcium channel blockers used to treat abnormal heart rhythms (arrhythmia) such as an irregular or rapid heart rate. On the other hand, it can also use to treat high blood pressure (hypertension) and heart failure. Arrhythmia is a condition in which your heart beats irregularly, too fast or too slow. Hypertension is a condition in which there is a persistent rise in blood pressure levels.

Vpl 5 mg Injection 10 x 2 ml contains Verapamil. It works by relaxing the blood vessels decreasing the workload on the heart. It also increases the blood and oxygen supply to the heart, thereby normalizing the electrical signals. These effects help to reduce blood pressure and also control the rate and rhythm of the heartbeat.

Vpl 5 mg Injection 10 x 2 ml will be administered by a healthcare professional; do not self-administer. In some cases, Vpl 5 mg Injection 10 x 2 ml may cause side effects such as injection site reactions, hypotension (low blood pressure), feeling dizzy or lightheaded, headaches, diarrhoea and being sick (vomiting). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before taking the Vpl 5 mg Injection 10 x 2 ml , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Vpl 5 mg Injection 10 x 2 ml can cause blurred vision and dizziness in some people, especially when they first start taking it or after a higher dose. If this occurs, do not drive a car, ride a bike, or operate tools or machinery. Do not consume any alcoholic beverages if you have heart problems.

Uses of Vpl 5 mg Injection 10 x 2 ml

Treatment of Arrhythmias and Hypertension

Directions for Use

Vpl 5 mg Injection 10 x 2 ml will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Vpl 5 mg Injection 10 x 2 ml contains Verapamil. It works by relaxing the blood vessels decreasing the workload on the heart. It also increases the blood and oxygen supply to the heart, normalizing electrical impulses. These effects help reduce blood pressure and control the rate and rhythm of the heartbeat.

How Vpl 5 mg Injection 10 x 2 ml Works

Vpl 5 mg Injection 10 x 2 ml contains Verapamil. It works by relaxing the blood vessels decreasing the workload on the heart. It also increases the blood and oxygen supply to the heart, thereby normalizing the electrical signals. These effects help to reduce blood pressure and also control the rate and rhythm of the heartbeat.

Storage

Store in a cool and dry place away from sunlight
Side effects of Vpl 5 mg Injection 10 x 2 ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.

What if I have taken an overdose of Vpl 5 mg Injection 10 x 2 ml

Since Vpl 5 mg Injection 10 x 2 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Vpl 5 mg Injection 10 x 2 ml may cause low blood pressure, slow heart rate, chest pain, shortness of breath, tiredness, high blood sugar, confusion, severe dizziness or fainting.

Drug Warnings

Before taking the Vpl 5 mg Injection 10 x 2 ml , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Inform your doctor if you have low blood pressure, kidney impairment, abnormally slow or irregular heartbeat, history of heart failure, or a heart condition called Wolff-Parkinson-White syndrome, myasthenia gravis (muscle disorders) or if you are treated with Ivabradine (medicine for a heart condition). And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Vpl 5 mg Injection 10 x 2 ml can cause blurred vision and dizziness in some people, especially when they first start taking it or after a higher dose. If this occurs, do not drive a car, ride a bike, or operate tools or machinery. It is recommended not to consume any alcoholic beverages.

Drug-Drug Interactions

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VerapamilDofetilide
Critical
VerapamilCisapride
Critical

Drug-Drug Interactions

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VerapamilDofetilide
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Using dofetilide together with Vpl 5 mg Injection 10 x 2 ml may significantly increase the blood levels of dofetilide. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Dofetilide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without first consulting a doctor.
VerapamilCisapride
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Coadministration of cisapride together with Vpl 5 mg Injection 10 x 2 ml may significantly increase the blood levels of cisapride. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Cisapride is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with cisapride.
VerapamilLomitapide
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Using lomitapide together with Vpl 5 mg Injection 10 x 2 ml may significantly increase the blood levels of lomitapide.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Lomitapide is generally avoided as it can possibly result in an interaction. Call a doctor if you experience diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, and yellowing of skin or eyes. Do not discontinue any medications without consulting a doctor.
VerapamilArbutamine
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Taking Vpl 5 mg Injection 10 x 2 ml with Arbutamine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Arbutamine together is generally avoided as it can result in an interaction, it can be taken when a doctor has advised it. However, if you experience irregular heartbeat, chest tightness, blurred vision, or nausea. contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VerapamilPimozide
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Using pimozide together with Vpl 5 mg Injection 10 x 2 ml can increase the blood levels and risk of developing irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Pimozide is generally avoided as it can cause an interaction. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VerapamilFlibanserin
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Using flibanserin together with Vpl 5 mg Injection 10 x 2 ml can significantly increase the blood levels of flibanserin.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Flibanserin is generally avoided as it can result in an interaction. Call a doctor immediately if you experience excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, fainting, and accidental injury, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VerapamilEliglustat
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
The metabolism of Eliglustat can be decreased when combined with Vpl 5 mg Injection 10 x 2 ml . This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VerapamilCobimetinib
Severe
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Taking Vpl 5 mg Injection 10 x 2 ml with Cobimetinib may significantly increase the blood levels of Cobimetinib. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Cobimetinib together with Vpl 5 mg Injection 10 x 2 ml can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, diarrhea, mouth sores, bleeding, heart problems (heart failure), rash, photosensitivity (increased sensitivity to sunlight), eye problems, liver injury, and muscle damage. Do not stop taking any medication without consulting a doctor.
VerapamilCarbamazepine
Severe
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Coadministration of Carbamazepine and Vpl 5 mg Injection 10 x 2 ml can alter the blood levels and effects of both medications.

How to manage the interaction:
Although taking carbamazepine and Vpl 5 mg Injection 10 x 2 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have symptoms such as headache, nausea, vomiting, dizziness, confusion, slurred speech, visual abnormalities, tremors, or incoordination, consult a doctor immediately. Do not stop using any medications without a doctor’s advice.
VerapamilCarvedilol
Severe
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Coadministration of Carvedilol with Vpl 5 mg Injection 10 x 2 ml can increase the risk or severity of side effects.

How to manage the interaction:
Although there may be an interaction, Carvedilol can be taken with Vpl 5 mg Injection 10 x 2 ml if prescribed by the doctor. However, consult the doctor if you experience headaches, swelling of legs and hands, shortness of breath, chest pain, or palpitations. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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VERAPAMIL-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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VERAPAMIL-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice with Vpl 5 mg Injection 10 x 2 ml can increase the blood levels and effects of Vpl 5 mg Injection 10 x 2 ml . Avoid the Consumption of Grapefruit juice with Vpl 5 mg Injection 10 x 2 ml . Contact a doctor if you experience sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest pain, or difficulty breathing.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

CALCIUM CHANNEL BLOCKERS
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Alcohol

Unsafe

Do not consume alcohol while using Vpl 5 mg Injection 10 x 2 ml as it may worsen your condition.

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Pregnancy

Caution

Vpl 5 mg Injection 10 x 2 ml should be used with caution in pregnancy as it may harm your unborn baby. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Vpl 5 mg Injection 10 x 2 ml .

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Breast Feeding

Caution

Vpl 5 mg Injection 10 x 2 ml should not be used in nursing mothers unless necessary. So, inform your doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Vpl 5 mg Injection 10 x 2 ml .

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Driving

Caution

Vpl 5 mg Injection 10 x 2 ml may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy after taking this medicine.

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Liver

Caution

Inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml if you have a pre-existing or a history of liver disease/condition. Your doctor may adjust the dose depending on your current liver condition.

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Kidney

Caution

Inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml if you have a pre-existing or a history of kidney disease/condition. Your doctor may adjust the dose depending on your current medical condition.

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Children

Safe if prescribed

Please consult your paediatrician. Your child's doctor will weigh the benefits and potential risks before prescribing Vpl 5 mg Injection 10 x 2 ml .

Have a query?

FAQs

Vpl 5 mg Injection 10 x 2 ml is used to treat Arrhythmias and Hypertension.

Vpl 5 mg Injection 10 x 2 ml contains Verapamil, which belongs to the class of calcium channel blockers. It works by relaxing the blood vessels making the blood flow easy. It also increases the blood and oxygen supply to the heart. These effects help reduce blood pressure and control the rate and rhythm of the heartbeat.

It is not recommended to take Vpl 5 mg Injection 10 x 2 ml with other medicines to treat high blood pressure, especially beta-blockers such as atenolol, propranolol, and metoprolol. It may cause an atrioventricular block (a type of heart block) and bradycardia (slow heart rate).

Vpl 5 mg Injection 10 x 2 ml is not suitable for patients with myasthenia gravis (muscle disorders); if you are suffering from myasthenia gravis, inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml .

Vpl 5 mg Injection 10 x 2 ml is contraindicated in people using Ivabradine. So, inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml if you are on treatment with Ivabradine.

Vpl 5 mg Injection 10 x 2 ml should not be taken in people with any degree of heart failure (unless you have a pacemaker), who are taking beta-blockers, who have severe hypotension (low blood pressure), who have severe bradycardia (low heart rate), and Wolff-Parkinson-White syndrome (rapid heart rate associated with dizziness).

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - VPL0001

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