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compositionComposition:CEFPODOXIME PROXETIL-50MG
prescription
Prescription Medicine
info
Xiss 50mg Tablet

Xiss 50mg Tablet is an antibiotic medicine used to treat bacterial infections of the ear, nose, throat, lower respiratory tract, urinary tract, skin, and soft tissue. This medicine contains Cefpodoxime Proxetil, which works by killing infection-causing bacteria. Common side effects include nausea, vomiting, diarrhoea, and abdominal pain.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFPODOXIME PROXETIL-50MG

Manufacturer/Marketer :

Colgen Pharma

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Xiss 50mg Tablet

Xiss 50mg Tablet is used to treat bacterial infections of the ear, nose, throat, lower respiratory tract, urinary tract, skin, and soft tissue. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body.

Xiss 50mg Tablet contains 'Cefpodoxime Proxetil', which is a broad-spectrum antibiotic effective against both gram-positive and gram-negative groups of bacteria. It works by preventing the formation of the bacterial cell covering (cell wall), which is necessary for their survival. Therefore, it kills the bacteria and helps treat and prevent the spread of bacterial infections.

Take this medicine as prescribed. In some cases, you may experience specific common side effects, such as nausea, vomiting, diarrhoea (watery or loose stool), abdominal pain, loss of appetite, bloating, skin rash, and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take antacids and anti-ulcer medications along with Xiss 50mg Tablet; maintain a 2-3 hour gap between them. Let your doctor know if you are pregnant or breastfeeding before starting Xiss 50mg Tablet. Avoid alcohol consumption to prevent unpleasant side effects. Xiss 50mg Tablet may cause dizziness; hence, drive or operate machinery only if you are alert.

Uses of Xiss 50mg Tablet

Xiss 50mg Tablet is used for the treatment of bacterial infections. The detailed uses of Xiss 50mg Tablet are as follows:

  • Treats bacterial infections: Xiss 50mg Tablet is effective against infections in the lungs (pneumonia), urinary tract, ear, nasal sinus, and throat
  • Manages respiratory conditions: Xiss 50mg Tablet is used for pharyngitis, tonsillitis, bronchitis, and sinusitis.
  • Helps with skin infections: Xiss 50mg Tablet treats uncomplicated skin and soft tissue infections.
  • Supports treatment of gonorrhea: Xiss 50mg Tablet is used for uncomplicated urethral and cervical gonorrhea.
  • Effective against otitis media: Xiss 50mg Tablet helps manage middle ear infections.

Key Benefits

  • Treats a wide range of bacterial infections effectively.
  • Works against infections of the respiratory tract such as bronchitis, pneumonia, and sinusitis.
  • Helps cure ear, nose, and throat infections including otitis media and tonsillitis.
  • Treats urinary tract infections (UTIs) caused by susceptible bacteria.
  • Effective in managing skin and soft tissue infections.
  • Provides reliable infection control with good tolerance and broad antibacterial coverage.

Directions for Use

  • Xiss 50mg Tablet can be taken with food to enhance its absorption, or as advised by your doctor.
  • Follow your doctor's instructions regarding dosage and timing to ensure optimal effectiveness.
  • Swallow Xiss 50mg Tablet whole with a glass of water.
  • Do not crush, break, or chew it.

How Xiss 50mg Tablet Works

Xiss 50mg Tablet contains Cefpodoxime Proxetil, which works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, it kills the bacteria and helps in treating bacterial infections.
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Alcohol

Safe

No interaction is found with alcohol. However, it is better to avoid/limit alcohol intake while using Xiss 50mg Tablet. For more information, please consult a healthcare professional.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant; your doctor will prescribe Xiss 50mg Tablet only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Cefpodoxime Proxetil may pass into the breast milk when used by a nursing mother. Please consult your doctor if you are breastfeeding before starting Xiss 50mg Tablet.

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Driving

Caution

Xiss 50mg Tablet may cause dizziness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have liver problems before taking Xiss 50mg Tablet.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment before taking Xiss 50mg Tablet.

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Children

Caution

Xiss 50mg Tablet should be used for children only if prescribed by the doctor. However, Xiss 50mg Tablet is not recommended for children under 2 months of age, as safety and efficacy have not been established.

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Heart

Consult your doctor

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Caution

Xiss 50mg Tablet should be given to elderly patients only if prescribed by a doctor. Seek medical advice if you have any concerns.

What if I have taken an overdose of Xiss 50mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Xiss 50mg Tablet may include nausea, vomiting, stomach pain, and diarrhoea. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help with indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, such as grapefruit and grapefruit juice, as they may hinder the absorption of antibiotics.
  • Avoid the consumption of alcohol to treat your condition effectively.
  • Avoid the use of tobacco.

Have a query?

How Soon It Starts Working

  • The time required for Xiss 50mg Tablet to start to work: Xiss 50mg Tablet ideally shows its action within 2 to 3 hours after administration.
  • The time for which the effects of Xiss 50mg Tablet last: The effect of Xiss 50mg Tablet lasts for 12 hours.

What if you forget to take Xiss 50mg Tablet

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid taking Xiss 50mg Tablet if you are allergic to any of its components.
  • Before taking Xiss 50mg Tablet, let your doctor know if you have/had inflammation in the bowel, kidney, or liver problems.
  • Do not take antacids or anti-ulcer medications along with Xiss 50mg Tablet, and maintain a gap of at least 2-3 hours between the two medicines.
  • Pregnant and breastfeeding women should seek medical advice before starting Xiss 50mg Tablet.
  • Avoid alcohol consumption while being treated with Xiss 50mg Tablet to prevent unpleasant side effects.
  • Xiss 50mg Tablet may cause dizziness, hence drive or operate machinery only if you are alert.

verifiedApollotooltip

Drug-Drug Interaction: Xiss 50mg Tablet may interact with water pills (furosemide), blood thinners (warfarin), supplements (calcium and vitamin D), antacids (cimetidine and ranitidine), and anti-gout medications (probenecid).

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: Let your doctor know if you have colitis (inflammation in the lining of the colon), seizures (epilepsy), kidney, and liver diseases before starting Xiss 50mg Tablet.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Xiss 50mg Tablet is used to treat bacterial infections of the ear, nose, throat, lower respiratory tract, urinary tract, skin, and soft tissue.
Xiss 50mg Tablet works by preventing the formation of a bacterial cell's covering, which is necessary for its survival. Thereby, it kills the bacteria and helps in treating and preventing the spread of infections.
Diarrhoea is the most commonly reported side effect of Xiss 50mg Tablet. So, it is advisable to drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you observe blood in stools (tarry stools) or experience excess diarrhoea (vomiting or watery stool), immediately consult your doctor. Do not take anti-diarrheal medicine on your own.
It is recommended to complete the course of Xiss 50mg Tablet, even if you feel better, as it is an antibiotic, and leaving it incomplete may lead to a severe infection that will stop responding to the antibiotic as well (antibiotic resistance).
Xiss 50mg Tablet may cause stomach upset as a side effect. To avoid this, take Xiss 50mg Tablet preferably with food. Taking Xiss 50mg Tablet with food helps in increasing its absorption in the body.
Do not take antacids or anti-ulcer medicines along with Xiss 50mg Tablet. Try to maintain a gap of at least 2-3 hours between the two medicines.
Xiss 50mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, loss of appetite, bloating and skin rash. If these side effects persist or worsen, please consult your doctor.
No, Xiss 50mg Tablet should not be taken without consulting the doctor. Xiss 50mg Tablet is a stronger antibiotic intended for severe infections, and your doctor will prescribe it only if necessary. It is not for viral infections such as the flu. Please consult your doctor so that appropriate medication is prescribed based on your condition.
Xiss 50mg Tablet is safe if used as per the dose and duration advised by the doctor. Do not exceed the recommended dose.
Yes, Xiss 50mg Tablet is an antibiotic. It belongs to the class of antibiotics known as cephalosporins.
Xiss 50mg Tablet usually starts working as soon as you take it. However, it may take a few days to kill all the harmful bacteria and relieve your symptoms completely.
If you do not feel better even after completing the full course of treatment with Xiss 50mg Tablet, inform your doctor. Also, let your doctor know if the symptoms worsen while using Xiss 50mg Tablet.
Yes, Xiss 50mg Tablet may be used to treat urinary tract infections (UTIs). According to studies, it has better tolerance and helps to effectively treat UTI symptoms such as frequent urination, foul smelling urine, vaginal discharge, vaginal irritation, stomach pain, etc. However, it is advisable to take Xiss 50mg Tablet only if prescribed by a doctor.
If you forget to take a dose of Xiss 50mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one, as this may increase the risk of side effects.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 065462S005Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. MedlinePlus. A698024 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Cefpodoxime Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. Cefpodoxime Proxetil [Drug Label]. 2003. [Accessed on 29 Mar. 2019] Check here
  5. CEFOPROX Tablets/DT/Powder for Oral Suspension [Internet]. CiplaMed. 2021 [Accessed on 8 October 2021] Check here
  6. Cefpodoxime (Oral Route) Before Using - Mayo Clinic [Internet]. Mayoclinic.org. 2021 [Accessed on 8 October 2021] Check here
  7. Vantin Tablets and Oral Suspension (cefpodoxime proxetil), USP [Internet]. Accessdata.fda.gov. 2021 [Accessed on 8 October 2021]Check here

Country of origin

India
Other Info - XI97514
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