Xygrel-AS Combikit 1's
MRP ₹367
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About Xygrel-AS Combikit
Xygrel-AS Combikit belongs to the class of antiplatelet drugs used to prevent heart attack and stroke. A heart attack is a critical medical emergency in which the blood supply to the heart is interrupted or blocked, typically by a blood clot. Signs of a heart attack include chest discomfort or pain, pain in other parts of the body, sweating, shortness of breath, nausea, fatigue and anxiety.
Xygrel-AS Combikit is a combination of two blood thinners: aspirin and ticagrelor. Xygrel-AS Combikit prevents platelets from adhering together, reducing the formation of harmful blood clots. This decreases the likelihood of having a heart attack or stroke.
Xygrel-AS Combikit should be taken after a meal or as directed by the physician. The common side effects of Xygrel-AS Combikit include mild indigestion, nausea, headache, dizziness, and joint pain. Most of these side effects do not necessitate medical treatment and fade away with time. However, if the side effects persist, consult your doctor.
Inform your doctor if you are allergic to ticagrelor or aspirin, have kidney/liver impairment, or have bleeding problems. Let your doctor know if you are pregnant, planning to become pregnant or are a nursing mother. Do not quit taking Xygrel-AS Combikit on your own without consulting a doctor. Stopping Xygrel-AS Combikit may aggravate your condition and raise the risk of having a further heart attack. Xygrel-AS Combikit may cause dizziness, so drive only if you are alert.
Uses of Xygrel-AS Combikit
Xygrel-AS Combikit is used in the prevention of heart attack or stroke. The detailed uses of Xygrel-AS Combikit are as follows:
- Acute Coronary Syndrome (ACS): Xygrel-AS Combikit reduces the risk of heart attack and stroke by preventing blood clots.
- Post-Myocardial Infarction (MI): Xygrel-AS Combikit helps prevent recurrence of heart attacks.
- Stent Thrombosis Prevention: Xygrel-AS Combikit is used after stent placement to keep arteries open.
- Percutaneous Coronary Intervention (PCI): Xygrel-AS Combikit supports recovery and reduces clot risk after procedures.
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Directions for Use
- Xygrel-AS Combikit can be taken with or without food, as advised by your doctor.
- Your doctor will decide the dosage and timing of this medication based on your medical condition.
- Swallow the whole Xygrel-AS Combikit with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
Xygrel-AS Combikit belongs to the class of medication called antiplatelet agents used to prevent heart attack and stroke. Xygrel-AS Combikit contains two blood thinners: aspirin and ticagrelor. Xygrel-AS Combikit prevents platelets from aggregation, thereby minimising the formation of harmful blood clots. This lowers the chances of having a heart attack or stroke.
How Xygrel-AS Combikit Works
Storage
- Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
- Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
- Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
- Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
- Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
- Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
- Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
- Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
- Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
- Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
- Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
- Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
- Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
- Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
- If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
- Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
- If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
- Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.
- Increased creatinine levels must be corrected immediately with the help of a doctor.
- Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
- Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
- Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
- Avoid smoking and drinking alcohol.
- Talk to your doctor about your back pain and potential medication substitutes or dose changes.
- Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
- To lessen the tension on your back, sit and stand upright and maintain proper posture.
- To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
- Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
- Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
- To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
- Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
- Back discomfort can worsen by bending, twisting, and heavy lifting.
- Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
What if I have taken an overdose of Xygrel-AS Combikit
Drug Warnings
Inform your doctor if you are allergic to ticagrelor or aspirin, have kidney/liver impairment, or have bleeding problems. Let your doctor know if you are pregnant, planning to become pregnant or are a nursing mother. Do not quit taking Xygrel-AS Combikit on your own without consulting a doctor. Stopping Xygrel-AS Combikit may aggravate your condition and raise the risk of having a further heart attack. Xygrel-AS Combikit may cause dizziness, so drive only if you are alert. Before taking Xygrel-AS Combikit, inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects.
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Xygrel-AS Combikit with Conivaptan can increase the risk of bleeding.
How to manage the interaction:
Taking Xygrel-AS Combikit with Conivaptan is not recommended, please consult your doctor before taking it. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Using Xygrel-AS Combikit together with Voriconazole can significantly increase the blood levels of Xygrel-AS Combikit.
How to manage the interaction:
Taking Xygrel-AS Combikit with Voriconazole is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Using Xygrel-AS Combikit together with indinavir can cause risk of bleeding.
How to manage the interaction:
Taking Xygrel-AS Combikit with Indinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Using Xygrel-AS Combikit together with telithromycin cause increase the blood levels of Xygrel-AS Combikit.
How to manage the interaction:
Taking Xygrel-AS Combikit with Telithromycin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Co-administration of posaconazole with Xygrel-AS Combikit can increase the risk of bleeding.
How to manage the interaction:
Taking Xygrel-AS Combikit with Posaconazole is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Co-administration of Mifepristone with Xygrel-AS Combikit can increase the risk of vaginal bleeding in women.
How to manage the interaction:
Taking Xygrel-AS Combikit with Mifepristone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any symptoms like heavy period bleed for more than 7 days, weakness, tiredness, shortness of breath or paleness. Do not discontinue any medications without consulting a doctor.
Co-administration of Xygrel-AS Combikit with ketoconazole can cause severe bleeding.
How to manage the interaction:
Taking Xygrel-AS Combikit with Ketoconazole is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Xygrel-AS Combikit with Ritonavir may significantly increase the blood levels of Xygrel-AS Combikit.
How to manage the interaction:
Taking Xygrel-AS Combikit with Ritonavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
The blood levels and effects of Xygrel-AS Combikit may be greatly increased when combined with itraconazole.
How to manage the interaction:
Itraconazole and Xygrel-AS Combikit may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
Combining Ketorolac tromethamine with Xygrel-AS Combikit can increase the risk of adverse effects.
How to manage the interaction:
Taking Xygrel-AS Combikit with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Eat at regular intervals and have a nutritious diet rich in fresh fruits and vegetables.
- Limit your alcohol consumption because it elevates blood pressure and increases the risk of heart disease.
- Maintain a healthy weight and exercise routine to keep your heart healthy.
- Your doctor will also teach you how to recognise and manage the early symptoms of heart disease.
- Losing weight and maintaining a healthy BMI are critical for improving cardiac health.
- Thirty minutes of daily physical activity can help avoid heart disease.
- To improve your cardiac health, quit smoking.
- Stress reduction is critical for maintaining a healthy heart. Yoga and meditation can help relax your thoughts.
Habit Forming
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Alcohol
Caution
Avoid consumption of alcohol as it may increase dizziness.
Pregnancy
Caution
It is not advised to use Xygrel-AS Combikit when pregnant. Please consult a doctor, your doctor may prescribe only if the benefits outweigh the risks.
Breast Feeding
Caution
Xygrel-AS Combikit should be used in nursing mothers only if clinically needed, and the benefits outweigh the risks. Please consult the doctor.
Driving
Caution
Xygrel-AS Combikit may cause drowsiness and dizziness, so drive or operate machinery only if you are alert.
Liver
Caution
Caution should be exercised while using Xygrel-AS Combikit in patients suffering from liver impairment. Please consult a doctor. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Caution
Caution should be exercised while using Xygrel-AS Combikit in patients suffering from kidney impairment. Please consult a doctor. Your doctor will prescribe only if the benefits outweigh the risks.
Children
Caution
The safety and efficacy of Xygrel-AS Combikit in children have not been demonstrated. For further information, please contact your doctor.
Heart
Please inform your doctor if you have a history of heart disease before taking Xygrel-AS Combikit. Your doctor will prescribe it only if the benefits outweigh the risks.
Geriatrics
Caution
Xygrel-AS Combikit should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Xygrel-AS Combikit.
FAQs
Xygrel-AS Combikit is used to prevent heart attack and stroke.
Xygrel-AS Combikit prevents platelets from aggregating, thereby minimising the formation of dangerous blood clots. This lowers the chances of having a heart attack or stroke.
Xygrel-AS Combikit may increase the risk of bleeding. Exercise caution when performing daily tasks such as shaving, cutting fingernails, or using sharp instruments. Inform your doctor if you are due to undergo any surgical procedure.
Yes, you can get vaccinated while on Xygrel-AS Combikit. However, it would be better to tell your doctor or nurse that you're taking an antiplatelet medication.
Do not discontinue Xygrel-AS Combikit without consulting your doctor. Stopping Xygrel-AS Combikit may aggravate your condition and raise the risk of having a further heart attack or stroke.
Avoid consuming grapefruit or grapefruit juice while taking Xygrel-AS Combikit since it may increase the effectiveness of Xygrel-AS Combikit. This elevates the chances of bleeding more easily.
You are recommended to avoid alcohol, grapefruit juice, and medications like apixaban or other anticoagulants while taking Xygrel-AS Combikit, as they increase bleeding risk. If you still have any concerns, discuss with your doctor.
Use of Xygrel-AS Combikit during menstruation may increase the risk of heavier or prolonged bleeding due to its blood-thinning effects. Therefore, please take your doctor’s advice before taking Xygrel-AS Combikit.
Yes, blood thinners may cause shortness of breath, which can sometimes indicate a serious condition like a heart attack. If you experience sudden or worsening shortness of breath or any unusual symptom, seek immediate medical attention.
Brilinta 90 contains only ticagrelor, while Xygrel-AS Combikit is a combination of two components as aspirin and ticagrelor used to prevent blood clots.
Your doctor decides the best time to take Xygrel-AS Combikit. Take it with or without food as advised. Follow your doctor's instructions regarding the timing and dosage for effective results.
Xygrel-AS Combikit causes side effects such as mild indigestion, pain and swelling in the joints, headache, dizziness, nausea, diarrhoea, constipation, and mild rash. However, please consult a doctor if these persist for longer durations.
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Reference
- https://www.medicines.org.uk/emc/product/2408/smpc#gref
- https://www.medicines.org.uk/emc/product/7606/smpc
- https://www.nhs.uk/medicines/ticagrelor/
- https://www.nhs.uk/medicines/low-dose-aspirin/about-low-dose-aspirin/
- https://www.drugs.com/drug-interactions/aspirin,aspirin-low-strength.html
- https://www.drugs.com/drug-interactions/ticagrelor.html
