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compositionComposition:NILUTAMIDE-150MG
prescriptionPrescription Medicine
Zandron 150 mg Tablet 10's

Zandron 150 mg Tablet is used to treat prostate cancer. It contains Nilutamide, which belongs to the class of androgen inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. Common side effects of Zandron 150 mg Tablet are nausea, dizziness, headache, diarrhoea, muscle weakness, confusion, hot flushes, loss of appetite, and difficulty breathing.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NILUTAMIDE-150MG

Manufacturer/Marketer :

Bryogen Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

Zandron 150 mg Tablet is an anti-androgen medicine used in the treatment of prostate cancer. Prostate cancer is a condition that occurs when the prostate gland cells increase abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc. It is used in the treatment of metastatic prostate cancer in combination with surgical castration.

Zandron 150 mg Tablet contains Nilutamide, which belongs to the class of androgen inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. 

Zandron 150 mg Tablet may cause certain side effects such as nausea, dizziness, headache, diarrhoea, muscle weakness, confusion, hot flushes, loss of appetite and difficulty breathing. These side effects usually disappear without any medical attention. Take Zandron 150 mg Tablet as prescribed by your doctor.

Zandron 150 mg Tablet should be avoided if you are allergic to it. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, and respiratory problems before taking Zandron 150 mg Tablet . Zandron 150 mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established. This medicine is only intended for male patients.

Uses of Zandron 150 mg Tablet

Zandron 150 mg Tablet is used in the treatment of Prostate Cancer. The detailed uses of Zandron 150 mg Tablet are as follows:

  • Advanced prostate cancer: Zandron 150 mg Tablet is primarily used in combination with surgical castration to treat metastatic (stage D2) prostate cancer. It works by blocking androgen receptors, preventing testosterone from stimulating cancer cell growth.
  • Hormone therapy adjunct: Zandron 150 mg Tablet may be used as part of androgen deprivation therapy (ADT) to manage hormone-sensitive prostate cancer, especially in patients who are not responding well to other treatments.
  • Slowing cancer progression: By reducing the effect of male hormones on prostate tissue, Zandron 150 mg Tablet helps slows the spread and progression of cancer cells, improving patient outcomes.

Key Benefits

Zandron 150 mg Tablet contains Nilutamide, which belongs to the class of androgen inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Zandron 150 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. It is mainly intended for use in men only.

Side effects of Zandron 150 mg Tablet
  • Zinc is essential for testosterone production, so include zinc-rich foods like oysters, nuts, seeds, and red meat in your diet.
  • Excessive alcohol intake is a significant contributor to testicular atrophy, so reduce or eliminate alcohol from your diet.
  • Engage in moderate-intensity exercise most days of the week to improve blood circulation and hormone production.
  • Wear loose-fitting underwear and pants to prevent pressure on the testicles.
  • Avoid prolonged exposure to hot environments like saunas or hot baths, as high temperatures can negatively impact sperm production.
  • If you notice any unusual changes in your testicles or have concerns about your testicular health, consult a doctor for a thorough evaluation.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.

Directions for Use

  • Zandron 150 mg Tablet can be taken with or without food.
  • It is advised to take Zandron 150 mg Tablet once daily at the same time each day; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow the whole tablet with a glass of water.
  • Do not break, chew or crush Zandron 150 mg Tablet .
Zandron 150 mg Tablet contains Nilutamide, which belongs to the class of androgen inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.
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Alcohol

Consult your doctor

The interaction of Zandron 150 mg Tablet with alcohol is unknown. It is advisable to consult your doctor if you have concerns.

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Pregnancy

Not applicable

Not intended for women.

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Breast Feeding

Not applicable

Not intended for women.

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Driving

Caution

Zandron 150 mg Tablet may decrease alertness or make you feel sleepy and dizzy. So, do not drive or operate heavy machinery while taking Zandron 150 mg Tablet until your vision improves.

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Liver

Caution

Zandron 150 mg Tablet should be used with caution, especially if you have a history of liver diseases/conditions. This medicine may cause hepatitis. Hence, inform your doctor if you observe symptoms such as nausea, dark yellow-coloured urine, or jaundice. Your doctor may adjust the dose based on your condition. Zandron 150 mg Tablet is contraindicated for patients with severe hepatic insufficiency.

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Kidney

Caution

Zandron 150 mg Tablet should be used with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose based on your condition. Zandron 150 mg Tablet is contraindicated for patients with severe renal insufficiency.

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Children

Unsafe

Zandron 150 mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established.

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Heart

Caution

If you have a history of heart disease, please inform the doctor before receiving Zandron 150 mg Tablet .

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Geriatrics

Consult your doctor

Limited information available about the use of Zandron 150 mg Tablet in geriatric patients. Please consult your physician.

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Zandron 150 mg Tablet may include dizziness, general discomfort, headache, nausea, and vomiting. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Diet & Lifestyle Advise

  • Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
  • It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer. 
  • Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
  • Maintain a healthy weight by doing regular simple exercises and yoga. 
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention. 
  • Avoid including high amounts of red meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

Have a query?

Drug Warnings

Zandron 150 mg Tablet should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical and medication history beforehand to rule out any side effects. Inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, or taking any other medicines before taking Zandron 150 mg Tablet as it may cause serious side effects. Zandron 150 mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established. Zandron 150 mg Tablet may cause intestinal pneumonitis hepatitis.

Drug-Drug Interactions

verifiedApollotooltip
NilutamideZiprasidone
Critical
NilutamideCeritinib
Severe

Drug-Drug Interactions

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NilutamideZiprasidone
Critical
How does the drug interact with Zandron 150 mg Tablet:
Using ziprasidone together with Zandron 150 mg Tablet can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Ziprasidone with Zandron 150 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
NilutamideCeritinib
Severe
How does the drug interact with Zandron 150 mg Tablet:
Taking ceritinib with Zandron 150 mg Tablet can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Co-administration of Ceritinib with Zandron 150 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience severe or long-lasting diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, having trouble breathing, or experiencing heart palpitations contact a doctor. Do not discontinue any medications without consulting a doctor.
NilutamideAmiodarone
Severe
How does the drug interact with Zandron 150 mg Tablet:
Coadministration of Amiodarone with Zandron 150 mg Tablet that can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Amiodarone with Zandron 150 mg Tablet together is not recommended as it can result in an interaction, it can be taken only if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, palpitations, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
NilutamideMoxifloxacin
Severe
How does the drug interact with Zandron 150 mg Tablet:
Using Moxifloxacin together with Zandron 150 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Moxifloxacin and Zandron 150 mg Tablet, but it can be taken if prescribed by a doctor. If you experience fast or irregular heartbeat, dizziness, difficulty breathing - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
NilutamideDisopyramide
Severe
How does the drug interact with Zandron 150 mg Tablet:
The combined use of Zandron 150 mg Tablet and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Zandron 150 mg Tablet and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
NilutamideHaloperidol
Severe
How does the drug interact with Zandron 150 mg Tablet:
Co-administration of Zandron 150 mg Tablet and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zandron 150 mg Tablet and Haloperidol can lead to an interaction, it can be taken when advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
NilutamideClozapine
Severe
How does the drug interact with Zandron 150 mg Tablet:
When Zandron 150 mg Tablet and Clozapine are taken together, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Zandron 150 mg Tablet with Clozapine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations. Do not stop using any medications without a doctor's advice.
NilutamideSotalol
Severe
How does the drug interact with Zandron 150 mg Tablet:
Using sotalol together with Zandron 150 mg Tablet can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Zandron 150 mg Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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No
[ANTINEOPLASTIC]

FAQs

Zandron 150 mg Tablet is used to treat prostate cancer.

Zandron 150 mg Tablet contains Nilutamide, which works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

No, do not stop taking Zandron 150 mg Tablet without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve.

Take Zandron 150 mg Tablet as advised by your doctor. However, if you forget or miss any dose of Zandron 150 mg Tablet , take it as soon as you remember unless it is time for your next dose. But do not double the dose.

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

India
LEVEL 20 DLF EPITOME BUILDING 5C DLF CYBER CITY , Gurugram, India, 122002
Other Info - ZAN0185

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