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Zavamet DP 100/500/10 Tablet 10's
Zavamet DP 100/500/10 Tablet 10's

Zavamet DP 100/500/10 Tablet is an antidiabetic medicine used to treat Type II Diabetes. It contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), Vildagliptin (dipeptidyl peptidase-4 inhibitor), and Metformin (biguanides), which work by increasing the amounts of certain natural substances that lower blood sugar when it is high. Zavamet DP 100/500/10 Tablet may cause side effects, such as vomiting, nausea, abdominal pain, headache, frequent urination, and allergic reactions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DAPAGLIFLOZIN-10MG+METFORMIN-500MG+VILDAGLIPTIN-100MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zavamet DP 100/500/10 Tablet

Zavamet DP 100/500/10 Tablet is an antidiabetic medicine used to treat diabetes. It is used for the treatment of Type II Diabetes. Type 2 Diabetes Mellitus is a chronic condition that affects the body's metabolism of glucose, or blood sugar. Insulin resistance or insufficient insulin production are the two main causes of type 2 diabetes.

Zavamet DP 100/500/10 Tablet contains dapagliflozin, vildagliptin, and metformin, which work by increasing the amounts of certain natural substances that lower blood sugar when it is high.

Zavamet DP 100/500/10 Tablet may cause certain side effects such as vomiting, nausea, abdominal pain, headache, frequent urination, and allergic reactions. If these side effects persist or worsen, please consult your doctor.

Zavamet DP 100/500/10 Tablet should be avoided if you are allergic to any of the medicines or their components. Let your doctor know if you are pregnant or breastfeeding before taking Zavamet DP 100/500/10 Tablet . It is not recommended for use in children below 18 years of age.

Uses of Zavamet DP 100/500/10 Tablet

Zavamet DP 100/500/10 Tablet is used in the treatment of Type II Diabetes Mellitus. The detailed uses of Zavamet DP 100/500/10 Tablet are as follows:

  • Type 2 Diabetes Management: Zavamet DP 100/500/10 Tablet is used to control high blood sugar levels in adults with type 2 diabetes. It combines three antidiabetic agents that work together to improve insulin sensitivity, reduce glucose production, and increase glucose excretion through urine.
  • Cardiovascular and Renal Protection: Zavamet DP 100/500/10 Tablet helps reduce the risk of heart failure and kidney complications associated with diabetes by lowering blood pressure, improving vascular function, and reducing albuminuria.
  • Weight and Metabolic Control: Zavamet DP 100/500/10 Tablet supports weight loss and improves metabolic parameters by reducing excess glucose in the body and enhancing insulin response, making it beneficial for overweight or obese diabetic patients.
  • HbA1c Reduction and Glycemic Stability: Zavamet DP 100/500/10 Tablet effectively lowers HbA1c levels and helps maintain stable blood glucose throughout the day, reducing the risk of hypoglycemia and long-term complications.

Key Benefits

  • Zavamet DP 100/500/10 Tablet  is a combination of three drugs, namely: Dapagliflozin, Vildagliptin, and Metformin.
  • Zavamet DP 100/500/10 Tablet belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus.
  • Vildagliptin enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations.
  • Dapagliflozin helps remove excess sugar from the body via urine.
  • Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines.
Side effects of Zavamet DP 100/500/10 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Take Zavamet DP 100/500/10 Tablet with or without food, or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Zavamet DP 100/500/10 Tablet Works

Zavamet DP 100/500/10 Tablet contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), Vildagliptin (dipeptidyl peptidase-4 inhibitor), and Metformin (biguanides), which work by increasing the amounts of certain natural substances that lower blood sugar when it is high.
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Alcohol

Unsafe

Alcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Zavamet DP 100/500/10 Tablet .

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Pregnancy

Consult your doctor

There are no adequate studies on the effect of Zavamet DP 100/500/10 Tablet in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Zavamet DP 100/500/10 Tablet .

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Breast Feeding

Consult your doctor

Zavamet DP 100/500/10 Tablet is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Zavamet DP 100/500/10 Tablet .

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Driving

Safe if prescribed

Zavamet DP 100/500/10 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Zavamet DP 100/500/10 Tablet with caution, as lactic acidosis can occur due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Renal impairment also increases the risk of lactic acidosis. Hence, Zavamet DP 100/500/10 Tablet should be used with caution if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Zavamet DP 100/500/10 Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

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Heart

Consult your doctor

Please consult your doctor before receiving Zavamet DP 100/500/10 Tablet if you have pre-existing heart problems. Your doctor will prescribe Zavamet DP 100/500/10 Tablet if the benefits outweigh the risks.

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Geriatrics

Safe if prescribed

Zavamet DP 100/500/10 Tablet requires careful monitoring due to an increased risk of side effects in geriatric patients. Therefore, it is important to consult a doctor before administering Zavamet DP 100/500/10 Tablet to elderly individuals.

What if I have taken an overdose of Zavamet DP 100/500/10 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Zavamet DP 100/500/10 Tablet may include low blood sugar and rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death.). Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Diet & Lifestyle Advise

  • Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly.
  • Include your diet with whole grain foods, fruits and veggies and other fibre-enriched foods.
  • Add omega-3 fatty acid-containing oils for daily cooking.
  • Avoid taking too much stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes, meditation, or yoga.
  • Loss of weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
  • Avoid smoking and alcohol consumption while on treatment with Zavamet DP 100/500/10 Tablet .
  • Take short, frequent meals, and avoid prolonged fasting when taking Zavamet DP 100/500/10 Tablet .

Have a query?

How Soon It Starts Working

  • The time required for Zavamet DP 100/500/10 Tablet to start to work: The time required for Zavamet DP 100/500/10 Tablet to show its action is not clinically established. 
  • The time for which the effects of Zavamet DP 100/500/10 Tablet last: The duration of action for Zavamet DP 100/500/10 Tablet is not clinically established.

What if you forget to take Zavamet DP 100/500/10 Tablet

If you miss a dose of Zavamet DP 100/500/10 Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Zavamet DP 100/500/10 Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Zavamet DP 100/500/10 Tablet should be avoided if you are allergic to any of the medicines or their components.
  • Before starting the treatment, inform your doctor about your medical history and the medications you take, including herbs and supplements, to rule out any side effects.
  • It is unknown whether Zavamet DP 100/500/10 Tablet can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding.
  • It is not recommended for use in children below 18 years of age.
  • Avoid drinking alcohol while on Zavamet DP 100/500/10 Tablet as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).
  • Inform your doctor if you have any liver/kidney disease, heart problems, or hypertension before taking Zavamet DP 100/500/10 Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions: Zavamet DP 100/500/10 Tablet interacts with an antidepressant (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), anti-epileptic drugs (topiramate, lamotrigine), and heart-related chest medicine (ranolazine).

Drug-Food Interactions: Intake of excessive alcoholic beverages may increase the chance of a life-threatening condition known as Lactic acidosis. So, avoid intake of alcoholic beverages with Zavamet DP 100/500/10 Tablet .

Drug-Disease Interactions: Inform your doctor if you have any kidney or liver disease or heart problems.

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Zavamet DP 100/500/10 Tablet is an antidiabetic medicine used for the treatment of Type II Diabetes.
Zavamet DP 100/500/10 Tablet is a combination medicine containing Vildagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines.
Please consult your doctor if you have concerns and for more information on this.
If you forget to take Zavamet DP 100/500/10 Tablet , take it as soon as you remember. However, if it is time for the next dose, avoid taking it and do not double dose to make up for the missed dose. Taking an overdose might cause your sugar level to fall down rapidly.
No, Zavamet DP 100/500/10 Tablet differs from Metformin, although both are used to treat type 2 diabetes. Zavamet DP 100/500/10 Tablet is a combination medication containing three active ingredients: dapagliflozin, vildagliptin, and Metformin. In contrast, Metformin is a single medication and is one of the components of Zavamet DP 100/500/10 Tablet . While Zavamet DP 100/500/10 Tablet has a combination action, Metformin works through a single mechanism of action. Your doctor will choose the appropriate treatment based on your diabetic condition.
Zavamet DP 100/500/10 Tablet can be taken with or without food as your doctor advises, and the timing can vary depending on individual needs. Generally, it's best to take it at the same time every day. Always follow your doctor's specific instructions regarding dosage and timing to ensure the best results.
Some individuals may experience certain side effects of Zavamet DP 100/500/10 Tablet , such as vomiting, nausea, abdominal pain, headache, frequent urination, and allergic reactions. If these side effects persist or worsen, please consult your doctor.
Zavamet DP 100/500/10 Tablet should be used with caution if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Dizziness is not a commonly reported side effect of Zavamet DP 100/500/10 Tablet . However, individual responses to the medication may vary. If you experience persistent dizziness, please consult your doctor for advice and relief.
No, Zavamet DP 100/500/10 Tablet is used to treat type 2 diabetes, not type 1 diabetes. These medications work by increasing the amounts of certain natural substances that lower blood sugar when it is high. For type 1 diabetes, different treatments are required, typically involving insulin therapy. Please consult your doctor for an appropriate treatment plan suitable for your needs.
Zavamet DP 100/500/10 Tablet generally does not cause pancreatitis. However, individual responses to the medication may vary. If you experience symptoms such as severe abdominal pain, nausea, or vomiting while taking Zavamet DP 100/500/10 Tablet , it's essential to seek medical attention immediately.
When taking Zavamet DP 100/500/10 Tablet , limit or avoid excessive alcohol, high-sugar foods like candy and cakes, unhealthy fats found in fried and fast food, and processed foods like packaged snacks and frozen meals. This helps manage blood sugar levels and reduces potential side effects.
Zavamet DP 100/500/10 Tablet is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid adverse complications.
No, don’t stop taking Zavamet DP 100/500/10 Tablet without consulting your doctor. Stopping this medication suddenly can lead to uncontrolled blood sugar levels and potential complications. It is essential to take medication as long as the doctor prescribes it to maintain blood sugar levels. Always discuss any concerns or reasons to discontinue the medication with your doctor. They will assess your health and provide suitable guidance.
Yes, proteins are necessary for people with diabetes. Protein is an essential nutrient that helps build and repair tissues and can also help manage blood sugar levels. Eat a balanced diet rich in protein and low in saturated fat, added sugars, and sodium. Consult with a registered dietitian or healthcare provider for personalized nutrition advice.
Artificial sweeteners can be a good alternative to sugar for people with diabetes, as they provide sweetness without raising blood sugar levels. If you are diabetic, consult a registered dietitian or healthcare provider for personalized advice on using artificial sweeteners.
Yes, diabetes can cause kidney failure. This condition is known as diabetic nephropathy or diabetic kidney disease. It occurs when high blood sugar levels damage the blood vessels in the kidneys, impairing their ability to filter waste and excess fluids from the body. Over time, this damage can lead to kidney failure. Controlling blood sugar levels and blood pressure and getting regular kidney check-ups can help prevent or slow kidney damage.
There is no cure for diabetes as of now. Researchers continuously explore various approaches to find a cure, including natural remedies, chemotherapy, homoeopathy, ayurveda, and allopathic medicine. However, diabetes can be managed effectively through proper diet, medication, and lifestyle changes.
No, don’t take Zavamet DP 100/500/10 Tablet more than the prescribed dose. Taking a higher dose will not provide additional benefits and may cause adverse health complications. Following your doctor's instructions and taking Zavamet DP 100/500/10 Tablet precisely as directed is crucial to ensure safe and effective treatment.

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Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ZAV0022

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