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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zecort-D Eye/Ear Drop is used to treat bacterial eye and ear infections. It contains gentamicin and dexamethasone. Gentamicin has bactericidal activity and works by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation, by inhibiting the chemicals, such as prostaglandins, that cause inflammation. Thus, it treats bacterial eye/ear infections.
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Whats That

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Synonym :

BETAMETHASONE SODIUM PHOSPHATE+GENTAMICIN SULFATE

Manufacturer/Marketer :

Martin & Harris Pvt Ltd

Consume Type :

EYE/EAR

Return Policy :

Not Returnable

Expires on or after :

About Zecort-D Eye/Ear Drop

Zecort-D Eye/Ear Drop is a combination of antibiotic and steroid medication used to treat bacterial eye and ear infections. An ear infection occurs when bacteria invade the middle or outer ear, causing pain and inflammation. Bacterial eye infection occurs when pathogenic bacteria enter any eye portion, including the eyeball, conjunctiva, and cornea.

Zecort-D Eye/Ear Drop contains gentamicin and dexamethasone. Gentamicin has bactericidal activity and works by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation, by inhibiting the chemicals, such as prostaglandins, that cause inflammation. As a result, Zecort-D Eye/Ear Drop treats bacterial eye/ear infections.

You are advised to use Zecort-D Eye/Ear Drop for as long as your doctor has prescribed it. Sometimes, you may experience certain common side effects, such as discomfort, stinging sensation, irritation and dysgeusia (taste disorder). Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not use Zecort-D Eye/Ear Drop if you are allergic to any of its components. Talk to your doctor if the irritation persists despite using Zecort-D Eye/Ear Drop for a week or if it worsens. Consult your doctor before using the Zecort-D Eye/Ear Drop if you are pregnant or breastfeeding. Please do not touch the tip of the dropper to the eye/ear or surrounding areas, as it may contaminate the contents. Zecort-D Eye/Ear Drop should be used in children only if prescribed by the doctor.

Uses of Zecort-D Eye/Ear Drop

Treatment of Bacterial eye and ear infections

Directions for Use

• Follow your doctor’s instructions regarding the dosage and duration.• For eye use: Wash your hands, tilt your head back, pull down your lower eyelid, and instil the prescribed number of drops into the eye.• For ear use: Lie on your side or tilt your head so the ear faces up and instil the prescribed number of drops into the ear.• Do not touch the tip of the dropper to avoid contamination.

Medicinal Benefits

Zecort-D Eye/Ear Drop consists of Gentamicin and dexamethasone. Gentamicin has bactericidal activity and functions by inhibiting the synthesis of key proteins required by bacteria to carry out vital functions. Dexamethasone is a steroid that lowers inflammation and infection-related symptoms such as redness and irritation by blocking the substances that induce inflammation, such as prostaglandins. As a result, Zecort-D Eye/Ear Drop aids in treating eye/ear infections.

How Zecort-D Eye/Ear Drop Works

Zecort-D Eye/Ear Drop contains gentamicin and dexamethasone. Gentamicin has bactericidal activity and works by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation, by inhibiting the chemicals, such as prostaglandins, that cause inflammation. As a result, Zecort-D Eye/Ear Drop treats bacterial eye/ear infections.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Zecort-D Eye/Ear Drop out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zecort-D Eye/Ear Drop

An overdose of Zecort-D Eye/Ear Drop may not be harmful. However, the risk of overdose cannot be excluded. Seek emergency medical attention or call your doctor if you notice any unusual symptoms, or anyone has accidentally swallowed the medication or if you suspect that you may have overdosed of Zecort-D Eye/Ear Drop.

Drug Warnings

Do not use Zecort-D Eye/Ear Drop if you are allergic to any of its components, corticosteroids, or aminoglycosides. Before using Zecort-D Eye/Ear Drop, inform your doctor if you have vision problems, active ocular tuberculosis, severe eye pain, glaucoma (high blood pressure), eye damage, eye surgery, hearing problems (cytotoxicity), a perforated eardrum, chronic otitis media, or viral ear infections (herpes simplex otitis externa and herpes zoster otitis external). If you are a pregnant woman or nursing mother, do not use the Zecort-D Eye/Ear Drop without first consulting your doctor. Contact your doctor if the infection symptoms persist or worsen after two weeks of treatment.

Drug-Drug Interactions

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DexamethasoneRilpivirine
Critical

Drug-Drug Interactions

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DexamethasoneRilpivirine
Critical
How does the drug interact with Zecort-D Eye/Ear Drop 10 ml:
When Rilpivirine is taken with Zecort-D Eye/Ear Drop 10 ml, may significantly reduce the blood levels of Rilpivirine.

How to manage the interaction:
Co-administration of Rilpivirine and Zecort-D Eye/Ear Drop 10 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zecort-D Eye/Ear Drop 10 ml:
Co-administration of Desmopressin with Zecort-D Eye/Ear Drop 10 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of Zecort-D Eye/Ear Drop 10 ml and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zecort-D Eye/Ear Drop 10 ml:
When Regorafenib is taken with Zecort-D Eye/Ear Drop 10 ml, may significantly reduce the blood levels of Regorafenib.

How to manage the interaction:
Co-administration of Regorafenib and Zecort-D Eye/Ear Drop 10 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zecort-D Eye/Ear Drop 10 ml:
When Zecort-D Eye/Ear Drop 10 ml is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine and Zecort-D Eye/Ear Drop 10 ml can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zecort-D Eye/Ear Drop 10 ml:
Co-administration of Vecuronium with Zecort-D Eye/Ear Drop 10 ml can make the treatment more effective.

How to manage the interaction:
Taking Vecuronium with Zecort-D Eye/Ear Drop 10 ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - having trouble breathing or feeling like you can't catch your breath for a long time - it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
GentamicinDoxacurium chloride
Severe
How does the drug interact with Zecort-D Eye/Ear Drop 10 ml:
Co-administration of Doxacurium with Zecort-D Eye/Ear Drop 10 ml may increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Zecort-D Eye/Ear Drop 10 ml and Doxacurium chloride, but it can be taken if prescribed by a doctor. If you have trouble breathing or feel like you can't breathe at all, it's important to contact a doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zecort-D Eye/Ear Drop 10 ml:
Co-administration of Zecort-D Eye/Ear Drop 10 ml and Temsirolimus may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Zecort-D Eye/Ear Drop 10 ml with Temsirolimus can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes like peeing more or less than usual, it's a good idea to let your doctor know right away. Some signs to watch out for include gaining weight quickly, feeling bloated, having trouble breathing, or feeling sick to your stomach. Other symptoms to be aware of are not feeling hungry, losing weight, swelling, muscle cramps, feeling weak or dizzy, feeling confused, or having an irregular heartbeat. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zecort-D Eye/Ear Drop 10 ml:
Using Zecort-D Eye/Ear Drop 10 ml with Botulinum toxin can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Botulinum toxin and Zecort-D Eye/Ear Drop 10 ml, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zecort-D Eye/Ear Drop 10 ml:
Co-administration of Magnesium sulfate with Zecort-D Eye/Ear Drop 10 ml can increase the risk of muscle weakness.

How to manage the interaction:
Although there is a possible interaction between Magnesium sulfate and Zecort-D Eye/Ear Drop 10 ml, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience muscle weakness and breathing difficulties. Do not stop using any medications without talking to a doctor.
GentamicinMannitol
Severe
How does the drug interact with Zecort-D Eye/Ear Drop 10 ml:
Co-administration of Mannitol with Zecort-D Eye/Ear Drop 10 ml can increase the risk of kidney damage.

How to manage the interaction:
There may be a possibility of interaction between Zecort-D Eye/Ear Drop 10 ml and Mannitol, but it can be taken if prescribed by a doctor. If you're having problems like hearing loss, ringing in your ears, feeling dizzy, or having kidney issues, it's important to let your doctor know right away. They may be able to recommend other options for you that won't cause these problems. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Ear infection:

  • Consult an ENT regularly to ensure early detection of any ear problems.
  • Avoid consuming foods you are allergic to, as it can cause the body to produce excess mucus, resulting in ear inflammation.
  • Avoid getting shampoo, soap, or water into your ears, as this can cause itching.
  • Poking or scratching the ear can cause damage to the ear canal, resulting in inflammation. 
  • Using cotton swabs, bobby pins, or other objects to remove earwax may push wax deeper into the ear, causing ear damage.
  • Never put cold water in your ear, and avoid spraying liquids into your ear with force.

Eye infection:

  • Get at least six to eight hours of sleep each night to renew your eyes.
  • Wash your eyes with clean water. If you have had eye surgery, wait at least two weeks before washing your eyes.
  • Take care of your health, eat a balanced diet, exercise regularly, and rest well.
  • Hydrate well-drink lots of water.
  • Wash your hands regularly, and avoid touching your eyes with dirty hands.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS AND STEROID
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Alcohol

Caution

No interaction was found. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

Zecort-D Eye/Ear Drop should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Zecort-D Eye/Ear Drop.

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Breast Feeding

Caution

Inform your doctor if you are a nursing mother before using Zecort-D Eye/Ear Drop; your doctor will decide whether Zecort-D Eye/Ear Drop can be used by breastfeeding mothers.

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Driving

Caution

Zecort-D Eye/Ear Drop may cause blurred vision temporarily after using the drops in the eye. Before driving or operating any machinery, wait until your vision is clear.

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Liver

Caution

Limited information is available on the usage of Zecort-D Eye/Ear Drop in patients with liver disease. Please inform your physician if you have had a liver impairment/disorder history. Your doctor will prescribe if the benefits outweigh the risks.

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Kidney

Caution

Limited information is available on the usage of Zecort-D Eye/Ear Drop in patients with kidney disease. Please inform your physician if you have had a kidney impairment/disorder history. Your doctor will prescribe if the benefits outweigh the risks.

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Children

Caution

Zecort-D Eye/Ear Drop should be used in children above one year only if prescribed by the doctor.

Have a query?

FAQs

Zecort-D Eye/Ear Drop is used to treat Bacterial eye and ear infections.

Gentamicin and dexamethasone are present in Zecort-D Eye/Ear Drop. Gentamicin has bactericidal activity and functions by inhibiting the synthesis of key proteins required by bacteria to carry out vital functions. Dexamethasone is a steroid that lowers inflammation and infection-related symptoms such as redness and irritation by blocking the substances that induce inflammation, such as prostaglandins. As a result, Zecort-D Eye/Ear Drop aids in treating eye/ear infections.

Please do not stop using Zecort-D Eye/Ear Drop until the course prescribed by the doctor has been completed. If you discontinue Zecort-D Eye/Ear Drop suddenly, your symptoms may reappear.

Wearing contact lenses during treatment is not recommended unless advised by the doctor. Remove the contact lenses before instilling the drops into the eye, and wait at least 15 minutes before reinserting them.

You are not recommended to use Zecort-D Eye/Ear Drop for more than the prescribed duration. Talk to your doctor if the irritation persists despite using Zecort-D Eye/Ear Drop for a week or if it worsens.

Zecort-D Eye/Ear Drop is a prescription medication that should be used only if prescribed by the doctor.

Country of origin

India

Manufacturer/Marketer address

A 22, Near, Asaf Ali Rd, Kamla Market, New Delhi, Delhi 110002
Other Info - ZEC0066

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