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  3. ZIDOVIR 100MG CAPSULE

ZIDOVIR 100MG CAPSULE, Pack of 10 CAPSULES
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

ZIDOVIR 100MG CAPSULE is used in the treatment of HIV. It contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This inhibits viral replication and thereby prevents the further spread of infection. Common side effects of this medication may include nausea, headache, stomach pain, loss of appetite, vomiting, nausea, cough, diarrhoea, nasal congestion, fever, tiredness, muscle pain, dizziness, and allergic reactions.

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Composition :

ZIDOVUDINE-100MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About ZIDOVIR 100MG CAPSULE

ZIDOVIR 100MG CAPSULE is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS). Symptoms of HIV include fever, chills, night sweats, muscle aches, etc. This medicine is also used for the prevention of maternal-fetal HIV transmission.

ZIDOVIR 100MG CAPSULE contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.

ZIDOVIR 100MG CAPSULE may cause certain side effects such as nausea, headache, stomach pain, loss of appetite, vomiting, nausea, cough, diarrhea, nasal congestion, fever, tiredness, muscle pain, dizziness, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. ZIDOVIR 100MG CAPSULE should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on your health condition. Do not take more than the recommended dose.

ZIDOVIR 100MG CAPSULE should be avoided if you are allergic to it. Before taking this medicine, inform your doctor if you have heart problems, liver/kidney diseases, haematological toxicity, severe anemia, hepatomegaly with steatosis, lactic acidosis, or peripheral nephropathy. If you are pregnant and breastfeeding, let your doctor know before taking ZIDOVIR 100MG CAPSULE. ZIDOVIR 100MG CAPSULE can be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. ZIDOVIR 100MG CAPSULE is used to treat the infection but does not cure or prevent it. Inform your doctor about your medical history and the medicines you take to prevent possible interactions.

Uses of ZIDOVIR 100MG CAPSULE

ZIDOVIR 100MG CAPSULE is used in the treatment and prevention of HIV (Human Immunodeficiency Virus) infection. The detailed uses of ZIDOVIR 100MG CAPSULE are as follows:<br/>• Treatment of HIV infection: ZIDOVIR 100MG CAPSULE, in combination with other antiretroviral medications, helps reduce HIV levels in the blood and slows disease progression.<br/>• Prevention of mother-to-child transmission: ZIDOVIR 100MG CAPSULE is used in HIV-positive pregnant women to lower the risk of passing the infection to their babies.<br/>• Delay progression to AIDS: ZIDOVIR 100MG CAPSULE reduces the risk of developing AIDS and associated complications like infections and certain cancers.<br/>• Part of comprehensive HIV management: ZIDOVIR 100MG CAPSULE is an nucleoside reverse transcriptase inhibitor (NRTI) that forms a key component of combination antiretroviral therapy (cART), supporting viral suppression and improved quality of life.<br/>

Directions for Use

• ZIDOVIR 100MG CAPSULE can be taken with or without food as prescribed by your doctor.• It is usually taken twice daily; however, follow your doctor's advice regarding the dosage and duration.• Swallow the capsule as a whole with a glass of water.• Do not open, chew or break the medicine.

Medicinal Benefits

ZIDOVIR 100MG CAPSULE contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection. ZIDOVIR 100MG CAPSULE is used in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Storage

• Store in a cool and dry place away from sunlight.
• Keep ZIDOVIR 100MG CAPSULE out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Zidovir 100mg Capsule
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Include fruits, vegetables, and whole grains in your diet.
  • Exercise regularly.
  • Quit smoking as it may increase the risk of neuropathy.
  • Getting massage therapy and acupuncture might help with pain.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of ZIDOVIR 100MG CAPSULE

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of ZIDOVIR 100MG CAPSULE may include extreme drowsiness/tiredness, confusion, and seizures. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

ZIDOVIR 100MG CAPSULE should be avoided if you are allergic to it. It is advised not to take this medicine along with ganciclovir, interferon alpha, ritonavir, stavudine, daunorubicin, bleomycin, idarubicin, and epirubicin, as it can cause serious side effects. Hence, avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, hematological toxicity, anemia, hepatomegaly with steatosis, lactic Acidosis, and peripheral nephropathy, on priority. It is not known whether ZIDOVIR 100MG CAPSULE can be given to pregnant and breastfeeding women. Hence, inform your doctor if you are pregnant and breastfeeding before receiving ZIDOVIR 100MG CAPSULE. ZIDOVIR 100MG CAPSULE can be used in children only if recommended by the pediatrician. If prescribed, the child should be carefully monitored for any changes. ZIDOVIR 100MG CAPSULE is used to treat the infection but does not cure or prevent it. ZIDOVIR 100MG CAPSULE is used to treat the infection but does not cure or prevent it. This medicine is used in combination for the treatment of HIV infection. This medicine may cause dizziness; hence, avoid driving or operating machines while taking ZIDOVIR 100MG CAPSULE.

Drug-Drug Interactions

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ZidovudineCladribine
Severe
ZidovudineBaricitinib
Severe

Drug-Drug Interactions

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ZidovudineCladribine
Severe
How does the drug interact with Zidovir 100mg Capsule:
Combining Cladribine with Zidovir 100mg Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Zidovir 100mg Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
ZidovudineBaricitinib
Severe
How does the drug interact with Zidovir 100mg Capsule:
coadministration of baricitinib and Zidovir 100mg Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Zidovir 100mg Capsule if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
ZidovudineClozapine
Severe
How does the drug interact with Zidovir 100mg Capsule:
Combining Zidovir 100mg Capsule with Clozapine can increase the risk of neutropenia.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and Zidovir 100mg Capsule, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - such as a severe infection, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain while urinating - it is important to contact your doctor right away." Do not stop using any medications without a doctor's advice.
ZidovudineEtanercept
Severe
How does the drug interact with Zidovir 100mg Capsule:
When Etanercept is used with Zidovir 100mg Capsule, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Etanercept with Zidovir 100mg Capsule together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
ZidovudineGanciclovir
Severe
How does the drug interact with Zidovir 100mg Capsule:
Using Zidovir 100mg Capsule together with ganciclovir may increase the risk of side effects affecting the blood leading to decreased levels of blood cells.

How to manage the interaction:
Taking ganciclovir with Zidovir 100mg Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, sore throat, rashes, tiredness, headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ZidovudineValganciclovir
Severe
How does the drug interact with Zidovir 100mg Capsule:
Combining Valganciclovir with Zidovir 100mg Capsule can increase the risk of side effects.

How to manage the interaction:
Although taking Valganciclovir and Zidovir 100mg Capsule together can cause an interaction, it can be taken if your doctor has suggested it. If you experience any complications or symptoms, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ZidovudineTofacitinib
Severe
How does the drug interact with Zidovir 100mg Capsule:
Taking Zidovir 100mg Capsule with Tofacitinib may increase the risk of serious infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Zidovir 100mg Capsule, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
ZidovudineInfliximab
Severe
How does the drug interact with Zidovir 100mg Capsule:
When Zidovir 100mg Capsule and Infliximab are taken together, the body breaks down Zidovir 100mg Capsule faster. This can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Zidovir 100mg Capsule together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin-rich and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

ZIDOVIR 100MG CAPSULE Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption while taking ZIDOVIR 100MG CAPSULE.

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Pregnancy

Consult your doctor

If you are pregnant or suspect you may be pregnant, inform your doctor before taking ZIDOVIR 100MG CAPSULE. Your doctor will prescribe a suitable dose of this medicine to prevent maternal-fetal HIV transmission.

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Breast Feeding

Unsafe

ZIDOVIR 100MG CAPSULE is excreted in milk. You should not nurse your child if you are taking this medicine because of the risk of HIV-1 transmission and serious adverse reactions in breastfeeding infants.

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Driving

Unsafe

Avoid driving vehicles after taking ZIDOVIR 100MG CAPSULE as it may cause dizziness and affect your ability to drive.

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Liver

Caution

ZIDOVIR 100MG CAPSULE should be used with caution in patients with mild to moderate liver impairment. In case of severe liver problems, it may increase the risk of hematologic toxicity. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Kidney

Caution

ZIDOVIR 100MG CAPSULE should be used with caution in patients with kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Safe if prescribed

Please consult your doctor. Your doctor will decide the dose of this medicine based on the age and condition of your child.

Have a query?

FAQs

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - ZID0007

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/019910s033lbl.pdf
  2. https://www.drugs.com/pregnancy/zidovudine.html
  3. https://medlineplus.gov/druginfo/meds/a687007.html
  4. https://www.mayoclinic.org/drugs-supplements/zidovudine-oral-route/side-effects/drg-20066724?p=1
  5. https://reference.medscape.com/drug/retrovir-zdv-zidovudine-342639

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