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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ziplan DS 1.5mg/2mg Tablet is an antipsychotic medication used to treat Schizophrenia. It contains Haloperidol and Trihexyphenidyl. Haloperidol is an antipsychotic that blocks dopamine receptors in the brain to reduce symptoms like hallucinations and delusions in schizophrenia. Trihexyphenidyl is an anticholinergic that helps prevent movement disorders caused by haloperidol. Together, they help improve schizophrenia symptoms effectively.

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Consume Type :

ORAL

Return Policy :

Not Returnable

About Ziplan DS 1.5mg/2mg Tablet

Ziplan DS 1.5mg/2mg Tablet is an antipsychotic medication used in the treatment of schizophrenia. Schizophrenia is a mental disorder that can significantly impact a person's quality of life. It can cause psychotic symptoms, including hallucinations (such as hearing voices), trouble managing thoughts, and being suspicious of others.

Ziplan DS 1.5mg/2mg Tablet is a combination medication. It contains Haloperidol and Trihexyphenidyl. Haloperidol is an antipsychotic that blocks dopamine receptors in the brain to reduce symptoms like hallucinations and delusions in schizophrenia. Trihexyphenidyl is an anticholinergic that helps prevent movement disorders caused by Haloperidol. Together, they effectively improve schizophrenia symptoms.

The dose and duration of Ziplan DS 1.5mg/2mg Tablet will be determined by your doctor based on your medical condition. Sometimes, Ziplan DS 1.5mg/2mg Tablet may cause common side effects such as sweating, headache, nausea, vomiting, urinary incontinence, dizziness, drowsiness, dry mouth, nasal congestion, menstrual changes, change in libido, swelling of the breasts and milk production in both men and women, weight changes, blurred vision, upset stomach, constipation, and difficulty urinating. Most of these side effects of Ziplan DS 1.5mg/2mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Ziplan DS 1.5mg/2mg Tablet if you are allergic to Ziplan DS 1.5mg/2mg Tablet or any of its ingredients. If you are pregnant or breastfeeding, inform your doctor before taking Ziplan DS 1.5mg/2mg Tablet. Ziplan DS 1.5mg/2mg Tablet is not recommended for children and if you have narrow-angle glaucoma. Ziplan DS 1.5mg/2mg Tablet may cause dizziness. Therefore, avoid driving or operating heavy machinery unless you are fully alert. You are recommended to avoid alcohol consumption with Ziplan DS 1.5mg/2mg Tablet as it may increase drowsiness or dizziness. Let your doctor know if you have any pre-existing medical conditions and if you are taking any other medications to rule out potential interactions.

Uses of Ziplan DS 1.5mg/2mg Tablet

Ziplan DS 1.5mg/2mg Tablet is used to treat schizophrenia. The detailed uses of Ziplan DS 1.5mg/2mg Tablet are as follows:<br/>• Manages schizophrenia: Ziplan DS 1.5mg/2mg Tablet helps reduce symptoms such as hallucinations, delusions, and disorganized thinking.<br/>• Controls mood and behavior: Ziplan DS 1.5mg/2mg Tablet aids in stabilizing mood and reducing agitation or aggressive behavior associated with psychotic disorders.<br/>• Prevents movement side effects: Ziplan DS 1.5mg/2mg Tablet contains trihexyphenidyl which helps prevent or reduce drug-induced movement problems (extrapyramidal symptoms) caused by antipsychotic treatment.<br/>

Directions for Use

• Ziplan DS 1.5mg/2mg Tablet can be taken with or without food or as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Swallow Ziplan DS 1.5mg/2mg Tablet as a whole with a glass of water.• Do not crush, chew or break it.

Medicinal Benefits

Ziplan DS 1.5mg/2mg Tablet contains Haloperidol and Trihexyphenidyl used in the treatment of schizophrenia. Haloperidol is an antipsychotic that blocks dopamine receptors in the brain to reduce symptoms like hallucinations and delusions in schizophrenia. Trihexyphenidyl is an anticholinergic, that helps prevent movement disorders caused by Haloperidol. Together, they effectively improve schizophrenia symptoms.

How Ziplan DS 1.5mg/2mg Tablet Works

Ziplan DS 1.5mg/2mg Tablet is an antipsychotic combination medication. It contains Haloperidol and Trihexyphenidyl. Haloperidol is an antipsychotic that works by blocking dopamine receptors in the brain, helping to reduce delusions and hallucinations in schizophrenia. Trihexyphenidyl is an anticholinergic that helps prevent movement-related side effects caused by Haloperidol. Together, they help manage schizophrenia symptoms effectively.

Storage

• Store in a cool and dry place away from sunlight.• Keep Ziplan DS 1.5mg/2mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Ziplan DS 1.5mg/2mg Tablet

Do not take more than the prescribed dose of Ziplan DS 1.5mg/2mg Tablet as it may cause an overdose. The symptoms of overdose include overdose symptoms include feeling hot, fever, paleness in the face, severe drowsiness, seizures, dilated pupils, dry skin and mouth, agitation, hallucinations, paranoia, numbness in or around the mouth, nose, or throat, confusion, dizziness, muscle stiffness or twitching, increased salivation, trouble swallowing, weakness, loss of balance or coordination, and fainting. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor before using Ziplan DS 1.5mg/2mg Tablet if you are allergic, if you have a history of heart disease, seizures, low blood pressure, or any other pre-existing medical conditions before using Ziplan DS 1.5mg/2mg Tablet. Ziplan DS 1.5mg/2mg Tablet may interact with alcohol and may cause increased drowsiness. So, avoid consumption of alcohol while taking Ziplan DS 1.5mg/2mg Tablet. Please inform your doctor as It may interact with anesthetics, and other central nervous system depressants, potentially requiring dosage adjustments for safe use. It may lower the seizure threshold, so inform your doctor if you have epilepsy, and continue your anticonvulsant medication as prescribed by the doctor. Elderly or debilitated patients (physically weak due to illness, age or chronic conditions) should be monitored for oversedation, which may lead to dehydration or breathing issues. Ziplan DS 1.5mg/2mg Tablet can cause drowsiness, so avoid activities requiring full alertness, such as driving or operating heavy machinery. Long-term use may lead to movement disorders like tardive dyskinesia, requiring dosage adjustments or discontinuation. It may also elevate prolactin levels, so patients with a history of breast cancer should consult their doctor before using Ziplan DS 1.5mg/2mg Tablet. Regular blood tests may be needed to monitor for blood disorders. Inform your doctor if you have glaucoma or gastrointestinal obstructions, as Ziplan DS 1.5mg/2mg Tablet may worsen these conditions. Inform your doctor if you are pregnant, breastfeeding, have pre-existing medications or if you are taking any other medicines before taking Ziplan DS 1.5mg/2mg Tablet.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Ziplan DS 1.5mg/2mg Tablet:
Taking Ziprasidone and Ziplan DS 1.5mg/2mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone and Ziplan DS 1.5mg/2mg Tablet together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Ziplan DS 1.5mg/2mg Tablet:
Coadministration of Fluphenazine and Ziplan DS 1.5mg/2mg Tablet can increase the risk of developing irregular heart rhythms.

How to manage the interaction:
Taking Fluphenazine and Ziplan DS 1.5mg/2mg Tablet together is generally avoided as it can lead to an interaction, but it can be taken when a doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
HaloperidolLevacetylmethadol
Critical
How does the drug interact with Ziplan DS 1.5mg/2mg Tablet:
Coadministration of Ziplan DS 1.5mg/2mg Tablet with Levacetylmethadol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Ziplan DS 1.5mg/2mg Tablet with Levacetylmethadol is not recommended as it can lead to serious side effects. It can be taken when advised by a doctor. Contact your doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ziplan DS 1.5mg/2mg Tablet:
Coadministration of Dronedarone and Ziplan DS 1.5mg/2mg Tablet can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dronedarone and Ziplan DS 1.5mg/2mg Tablet together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
HaloperidolMesoridazine
Critical
How does the drug interact with Ziplan DS 1.5mg/2mg Tablet:
Coadministration of Mesoridazine and Ziplan DS 1.5mg/2mg Tablet can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Mesoridazine and Ziplan DS 1.5mg/2mg Tablet together is not recommended as it can lead to an interaction, it can be taken when your doctor advises. Contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting your doctor.
HaloperidolLomitapide
Critical
How does the drug interact with Ziplan DS 1.5mg/2mg Tablet:
Coadministration of Ziplan DS 1.5mg/2mg Tablet with Lomitapide can increase the levels and risk of developing Lomitapide side effects

How to manage the interaction:
Taking Ziplan DS 1.5mg/2mg Tablet with Lomitapide is not recommended as it can lead to serious side effects, it can be taken when prescribed by your doctor. If you experience any symptoms like nausea, vomiting, stomach pain, loss of appetite, tiredness, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Ziplan DS 1.5mg/2mg Tablet:
Coadministration of Cisapride and Ziplan DS 1.5mg/2mg Tablet can increase the risk of developing irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Cisapride and Ziplan DS 1.5mg/2mg Tablet together is generally avoided as it can lead to an interaction, but it can be taken if your doctor advises. Contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Ziplan DS 1.5mg/2mg Tablet:
Combining Thioridazine and Ziplan DS 1.5mg/2mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Thioridazine and Ziplan DS 1.5mg/2mg Tablet together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
HaloperidolEliglustat
Critical
How does the drug interact with Ziplan DS 1.5mg/2mg Tablet:
Coadministration of Eliglustat and Ziplan DS 1.5mg/2mg Tablet can increase the blood levels and side effects of Ziplan DS 1.5mg/2mg Tablet.

How to manage the interaction:
Taking Ziplan DS 1.5mg/2mg Tablet with Eliglustat is not recommended, please consult your doctor before taking it. If you experience any side effects like dizziness, drowsiness, difficulty urinating, sleep disturbances, headache, or anxiety, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Ziplan DS 1.5mg/2mg Tablet:
Coadministration of Sparfloxacin with Ziplan DS 1.5mg/2mg Tablet can prolong the QT interval.

How to manage the interaction:
Taking Ziplan DS 1.5mg/2mg Tablet with Sparfloxacin is not recommended, but it can be taken if prescribed by your doctor. If you experience any symptoms, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a well-balanced diet with plenty of fruits, vegetables, whole grains, and lean proteins to support overall health.
  • Monitor weight, as some antipsychotics may cause weight gain, so regular physical activity and portion control are essential.
  • Stay hydrated by drinking enough water daily to prevent dehydration and support metabolic function.
  • Exercise regularly, such as walking, yoga, or strength training, to help with mood and weight control.
  • Maintain a regular sleep schedule to support mental and physical health.
  • Manage stress by practicing relaxation techniques like meditation, deep breathing, or hobbies to improve well-being.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS
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Alcohol

Caution

You are recommended to avoid alcohol consumption with Ziplan DS 1.5mg/2mg Tablet as it may cause increased drowsiness or dizziness.

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Pregnancy

Consult your doctor

Consult your doctor if you are pregnant, as this medication falls under Category C. It should only be used if the potential benefits outweigh the risks to the fetus.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Ziplan DS 1.5mg/2mg Tablet if used in breastfeeding. Hence, if you are a nursing mother, inform your doctor before taking Ziplan DS 1.5mg/2mg Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Ziplan DS 1.5mg/2mg Tablet may cause dizziness. Therefore, avoid driving or operating heavy machinery unless you are fully alert.

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Liver

Caution

Inform your doctor if you have liver disease, as Ziplan DS 1.5mg/2mg Tablet should be used with caution. However, it is not recommended for those with severe liver conditions.

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Kidney

Caution

Inform your doctor if you have kidney disease, as Ziplan DS 1.5mg/2mg Tablet should be used with caution. However, it is not recommended for those with severe liver conditions.

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Children

Consult your doctor

Ziplan DS 1.5mg/2mg Tablet is not recommended for children as safety and effectiveness were not established. Please consult the doctor for proper evaluation and guidance.

Have a query?

FAQs

Ziplan DS 1.5mg/2mg Tablet is an antipsychotic medication used to treat Schizophrenia.

Ziplan DS 1.5mg/2mg Tablet is a combination medication. It contains Haloperidol and Trihexyphenidyl. Haloperidol is an antipsychotic that works by blocking dopamine receptors in the brain, helping to reduce delusions and hallucinations in schizophrenia. Trihexyphenidyl is an anticholinergic that helps prevent movement-related side effects caused by Haloperidol. Together, they help manage schizophrenia symptoms effectively.

Ziplan DS 1.5mg/2mg Tablet may cause weight gain in some patients. However, to avoid gaining weight while receiving Ziplan DS 1.5mg/2mg Tablet, you are advised to exercise regularly and avoid high-calorie drinks. Instead, take non-alcoholic drinks, herbal tea and lemon water.

The side effects of Ziplan DS 1.5mg/2mg Tablet include sweating, headache, nausea, vomiting, urinary incontinence, dizziness, drowsiness, dry mouth, nasal congestion, menstrual changes, change in libido, swelling of the breasts and milk production in both men and women, weight changes, blurred vision, upset stomach, constipation, and difficulty urinating. Most of these side effects of Ziplan DS 1.5mg/2mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not stop taking Ziplan DS 1.5mg/2mg Tablet on your own, as it may worsen your medical condition. Therefore, always follow the prescribed dose and duration by your doctor to treat your condition effectively.

Country of origin

India
Other Info - ZI86588

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