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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zoladex LA 10.8 mg Injection is indicated in the treatment of breast cancer, endometriosis, uterine fibroids and infertility in women. It is also used to treat prostate cancer in men. It contains Goserelin, which acts on the brain's pituitary gland and decreases the production of certain sex hormones (testosterone in men and oestrogen in women) in the body. In some cases, Zoladex LA 10.8 mg Injection may cause hot flushes, sweating, decreased sex drive, and injection site reactions such as pain, redness, swelling, bleeding or bruising.

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Whats That

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Synonym :

GOSERELIN ACETATE

Composition :

GOSERELIN-10.8MG

Manufacturer/Marketer :

Astra Zeneca Pharma India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Zoladex LA 10.8 mg Injection

Zoladex LA 10.8 mg Injection belongs to the group of medicines called LHRH analogues indicated in the treatment of breast cancer, endometriosis, uterine fibroids and infertility in women. It is also used to treat prostate cancer in men.

Zoladex LA 10.8 mg Injection contains Goserelin, which works by acting on the pituitary gland in the brain and decreases the production of certain sex hormones (testosterone in men and oestrogen in women) in the body.

In some cases, Zoladex LA 10.8 mg Injection may cause hot flushes, sweating, decreased sex drive, and injection site reactions such as pain, redness, swelling, bleeding or bruising. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Zoladex LA 10.8 mg Injection if you are pregnant (except for breast cancer and infertility treatment) or breastfeeding. Zoladex LA 10.8 mg Injection is not recommended for children as safety and effectiveness have not been established. Inform the doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Zoladex LA 10.8 mg Injection

Zoladex LA 10.8 mg Injection is used in the treatment of Breast cancer, endometriosis, uterine fibroids and infertility in women. It is also used in the treatment of Prostate cancer in men

Directions for Use

Injection: It will be administered by a healthcare professional; do not self-administer.Implant: It will be inserted subcutaneously by a doctor in a hospital/clinic.

Medicinal Benefits

Zoladex LA 10.8 mg Injection belongs to the group of medicines called LHRH analogues indicated in the treatment of breast cancer, endometriosis, uterine fibroids and infertility in women. It is also used to treat prostate cancer in men. Zoladex LA 10.8 mg Injection contains Goserelin, which acts on the brain's pituitary gland and decreases the production of certain sex hormones (testosterone in men and oestrogen in women) in the body.

How Zoladex LA 10.8 mg Injection Works

Zoladex LA 10.8 mg Injection contains Goserelin, which works by acting on the pituitary gland in the brain and decreases the production of certain sex hormones (testosterone in men and oestrogen in women) in the body.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Zoladex LA 10.8 mg Injection

As Zoladex LA 10.8 mg Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not use Zoladex LA 10.8 mg Injection if you are allergic to any of its components, if you are pregnant (except for breast cancer and infertility treatment) or if you are breastfeeding. Consult the doctor immediately if you become pregnant during treatment. Inform the doctor if you have high blood pressure, heart or blood vessel conditions, heart rhythm problems, bone problems, problems passing urine, diabetes, unusual vaginal bleeding, electrolyte imbalance, heart failure, liver or kidney disease, a family history of osteoporosis, if you smoke or have a poor diet, take medicines like corticosteroids or anticonvulsants or if you develop depressed mood. Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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GoserelinHalofantrine
Critical
GoserelinAnagrelide
Critical

Drug-Drug Interactions

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GoserelinHalofantrine
Critical
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Halofantrine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and halofantrine together is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinAnagrelide
Critical
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Anagrelide with Zoladex LA 10.8 mg Injection can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Anagrelide with Zoladex LA 10.8 mg Injection is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinRibociclib
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Ribociclib can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and Ribociclib together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinQuinidine
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection with Quinidine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection with Quinidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinMethadone
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Methadone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and methadone together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinMoxifloxacin
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Using Moxifloxacin together with Zoladex LA 10.8 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Zoladex LA 10.8 mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, or irregular heartbeat, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
GoserelinIbutilide
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Ibutilide can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and ibutilide together can possibly result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinHaloperidol
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Coadministration of Zoladex LA 10.8 mg Injection and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and haloperidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
GoserelinPapaverine
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Papaverine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and papaverine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GoserelinIvabradine
Severe
How does the drug interact with Zoladex LA 10.8 mg Injection:
Taking Zoladex LA 10.8 mg Injection and Ivabradine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zoladex LA 10.8 mg Injection and ivabradine together can result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Consult your doctor

It is not known if alcohol affects Zoladex LA 10.8 mg Injection. Please consult your doctor.

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Pregnancy

Caution

Zoladex LA 10.8 mg Injection should not be used during pregnancy unless for palliative treatment of advanced breast cancer or infertility. Avoid becoming pregnant during treatment and for 12 weeks after your treatment as it may cause foetal harm.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Zoladex LA 10.8 mg Injection.

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Driving

Safe if prescribed

Zoladex LA 10.8 mg Injection is unlikely to affect your ability to drive. However, drive or operate heavy machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, inform the doctor before receiving Zoladex LA 10.8 mg Injection.

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Kidney

Consult your doctor

If you have a history of kidney disease, inform the doctor before receiving Zoladex LA 10.8 mg Injection.

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Children

Unsafe

Zoladex LA 10.8 mg Injection is not recommended for children as safety and effectiveness have not been established.

FAQs

Zoladex LA 10.8 mg Injection is used in the treatment of breast cancer, endometriosis, uterine fibroids and infertility in women. It is also used to treat prostate cancer in men.

Zoladex LA 10.8 mg Injection works by acting on the pituitary gland in the brain and decreases the production of certain sex hormones in the body.

Zoladex LA 10.8 mg Injection may decrease bone density, which may increase the chances of fractures or broken bones. Talk to the doctor about the risks and how to prevent them.

Zoladex LA 10.8 mg Injection might affect blood glucose levels. Therefore, if you have diabetes, inform the doctor. Monitor blood sugar levels more frequently while on treatment with Zoladex LA 10.8 mg Injection.

Avoid using oral contraceptives such as ‘the pill’ whilst on treatment with Zoladex LA 10.8 mg Injection. Instead, use barrier methods of contraception such as condoms or diaphragm.

There have been reports of depression in patients receiving Zoladex LA 10.8 mg Injection. Consult the doctor if you develop a depressed mood.

Country of origin

India

Manufacturer/Marketer address

Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Other Info - ZOL0022

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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