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  1. Home
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  3. Zosialfa Tablet PR

Prescription drug
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Zosialfa Tablet PR, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zosialfa Tablet PR is used to treat the symptoms of Benign prostatic hypertrophy (enlarged prostate gland). It contains Afluzosin, which relaxes the muscles of the bladder and prostate; this reduces the narrowing of the urethra. Thereby, helps in relieving the symptoms of benign prostatic hyperplasia (BPH) and makes it easier to pass urine.

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Synonym :

ALFUZOSIN HYDROCHLORIDE

Composition :

ALFUZOSIN-10MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zosialfa Tablet PR

Zosialfa Tablet PR is used to treat the symptoms of benign prostatic hypertrophy. Benign prostatic hyperplasia occurs due to the non-cancerous enlargement of the prostate gland, caused by the multiplication of cells. Benign prostatic hypertrophy/hyperplasia mostly occurs in older men.

Zosialfa Tablet PR contains Alfuzosin that works by blocking the receptors (alpha 1) on the prostate gland, bladder and urethra (urine pipe). Zosialfa Tablet PR relaxes the muscles of the bladder and prostate, reducing the narrowing of the urethra.

In some cases, you may experience common side effects such as dizziness, nausea, vomiting, diarrhoea, stomach pain, headache, and dry mouth. Most of these side effects will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Avoid taking Zosialfa Tablet PR if you are allergic to it. Rise slowly from a sitting/lying position as Zosialfa Tablet PR may cause dizziness or weakness. Zosialfa Tablet PR is intended for use in men only; women should not take Zosialfa Tablet PR, especially pregnant or breastfeeding women. Zosialfa Tablet PR should not be given to children as safety and efficacy have not been established. Zosialfa Tablet PR may cause dizziness, so drive with caution.

Uses of Zosialfa Tablet PR

Zosialfa Tablet PR is used in the treatment of benign prostatic hyperplasia (BPH). The detailed uses of Zosialfa Tablet PR are as follows:

  • Treats BPH (enlarged prostate) : Zosialfa Tablet PR helps manage symptoms of BPH in men, such as painful urination, difficulty urinating, incomplete bladder emptying, leakage of urine, and frequent or urgent need to urinate, especially at night.
  • Improves Urine Flow: Zosialfa Tablet PR relaxes the muscles of the bladder and prostate, thereby reducing pressure on the urethra and facilitating easier urination.
  • Reduces Risk of Urinary Retention (UR): Zosialfa Tablet PR helps lower the chances of postoperative UR after urologic surgery and reduces the need for urinary catheterisation due to acute UR.
  • Delays Need for Prostate Surgery: By effectively controlling BPH symptoms, Zosialfa Tablet PR can delay or reduce the need for surgical intervention in some cases.

Have a query?

Directions for Use

  • Zosialfa Tablet PR should be taken with food or as advised by a doctor.
  • Take Zosialfa Tablet PR once daily with the same meal each day as advised by a doctor.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Zosialfa Tablet PR belongs to the group of medicines called alpha-blockers.
  • Zosialfa Tablet PR is used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia) in men.
  • Zosialfa Tablet PR relieves the symptoms of benign prostatic hyperplasia by blocking the receptors (alpha 1) on the prostate gland, bladder and urethra (urine pipe).
  • Zosialfa Tablet PR works by relaxing the muscles of the bladder and prostate; this reduces the narrowing of the urethra.
  • It helps in relieving the symptoms of benign prostatic hyperplasia and makes it easier to pass urine.
  • Zosialfa Tablet PR is used to treat symptoms of benign prostatic hyperplasia such as painful urination, difficulty in urination, excess urination, incomplete urination, leakage of urine, dribbling at the end of the urinary stream, and urgency in urination.

How Zosialfa Tablet PR Works

Zosialfa Tablet PR contains Alfuzosin that works by blocking the receptors (alpha 1) on the prostate gland, bladder and urethra (urine pipe). Zosialfa Tablet PR relaxes the muscles of the bladder and prostate; this reduces the narrowing of the urethra. Thereby, helps in relieving the symptoms of benign prostatic hyperplasia and makes it easier to pass urine.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Zosialfa Tablet PR
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.

What if I have taken an overdose of Zosialfa Tablet PR

Do not take more than the prescribed dose of Zosialfa Tablet PR as it may cause overdose. The symptoms of overdose include low blood pressure, dizziness, fainting, lightheadedness, nausea and blurred vision. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Zosialfa Tablet PR if you are allergic to any of its contents.
  • Also, avoid taking Zosialfa Tablet PR if you are taking any other alpha-blockers, if you have postural hypotension or severe liver problems.
  • Inform your doctor if you have angina, urinary tract infections or crystals in the formed water, high blood pressure, circulatory problems, heart problems; if you are due to undergo any surgery that requires anaesthesia; if you are older than 65years or if you get painful erections before or during the treatment that will not go away.
  • Talk to your doctor before taking Zosialfa Tablet PR if you are undergoing eye surgery.
  • Zosialfa Tablet PR is intended for use in men only; women should not take Zosialfa Tablet PR, especially those who are pregnant or breastfeeding.
  • Zosialfa Tablet PR should not be given to children as safety and efficacy have not been established.
  • Zosialfa Tablet PR may cause dizziness, so drive with caution.
  • Avoid or limit alcohol consumption with Zosialfa Tablet PR as it could lead to increased dizziness.
  • Rise slowly from a sitting/lying position as Zosialfa Tablet PR can cause dizziness or weakness.

Drug-Drug Interactions

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AlfuzosinKetoconazole
Critical
AlfuzosinIdelalisib
Critical

Drug-Drug Interactions

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AlfuzosinKetoconazole
Critical
How does the drug interact with Zosialfa Tablet PR:
Using Zosialfa Tablet PR together with ketoconazole may significantly increase the blood levels of Zosialfa Tablet PR, which may result in side effects.

How to manage the interaction:
Taking Zosialfa Tablet PR with Ketoconazole is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fainting, headache, flushing, nasal congestion, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinIdelalisib
Critical
How does the drug interact with Zosialfa Tablet PR:
When Idelalisib is taken with Zosialfa Tablet PR, it can lower the metabolism of Zosialfa Tablet PR. This can increase the risk or severity of side effects like low blood pressure.

How to manage the interaction:
Taking Zosialfa Tablet PR with Idelalisib is not recommended as it can possibly result in an interaction, it should be taken only if your doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection), contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinDronedarone
Critical
How does the drug interact with Zosialfa Tablet PR:
Coadministration of Dronedarone with Zosialfa Tablet PR can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dronedarone with Zosialfa Tablet PR together is not recommended, as it leads to an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, shortness of breath, chest discomfort, or palpitations, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinClarithromycin
Critical
How does the drug interact with Zosialfa Tablet PR:
When Zosialfa Tablet PR and Clarithromycin can increase the risk or severity of side effects like low blood pressure or irregular heart rates.

How to manage the interaction:
Taking clarithromycin with Zosialfa Tablet PR is not recommended as it can result in an interaction; it should be taken only if your doctor has advised it. However, if you experience dizziness, headache, palpitations, or chest discomfort, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinTipranavir
Critical
How does the drug interact with Zosialfa Tablet PR:
When Zosialfa Tablet PR and Tipranavir are taken together, the body's ability to break down Zosialfa Tablet PR may be reduced. This increases the risk and severity of side effects.

How to manage the interaction:
Taking Zosialfa Tablet PR with Tipranavir is not recommended as it can possibly result in an interaction. It should be taken only when advised by a doctor. However, if you experience symptoms like severe dizziness, fainting, fast/irregular heartbeat, chest pain, fast or irregular heartbeat, nausea, or sweating contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinTelaprevir
Critical
How does the drug interact with Zosialfa Tablet PR:
Taking Telaprevir with Zosialfa Tablet PR can increase the blood levels and effects of Zosialfa Tablet PR. This can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Telaprevir with Zosialfa Tablet PR is not recommended as it can possibly result in an interaction, it can be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinAtazanavir
Critical
How does the drug interact with Zosialfa Tablet PR:
Concomitant use of Zosialfa Tablet PR with Atazanavir can increase the risk of low blood pressure.

How to manage the interaction:
Coadministration of Zosialfa Tablet PR with Atazanavir is not recommended, however, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience dizziness, palpitations, difficulty swallowing, or sweating. It is recommended to monitor your blood pressure regularly. Do not discontinue any medications without first consulting your doctor.
AlfuzosinHalofantrine
Critical
How does the drug interact with Zosialfa Tablet PR:
Taking Zosialfa Tablet PR with halofantrine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zosialfa Tablet PR and halofantrine together is generally avoided as it can result in an interaction. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinCeritinib
Critical
How does the drug interact with Zosialfa Tablet PR:
Coadministration of Zosialfa Tablet PR and ceritinib can increase the risk of developing side effects.

How to manage the interaction:
Taking Ceritinib with Zosialfa Tablet PR is not recommended as it can result in an interaction; it should be taken only if your doctor has advised it. However, if you experience dizziness, headache, palpitations, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinVoriconazole
Critical
How does the drug interact with Zosialfa Tablet PR:
Using Zosialfa Tablet PR together with voriconazole may significantly increase the blood levels and effects of Zosialfa Tablet PR.

How to manage the interaction:
Taking Voriconazole with Zosialfa Tablet PR is not recommended, please consult a doctor before taking it. Call a doctor if you experience dizziness, headache, nasal congestion, or heart palpitation. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Urinate as soon as you feel the urge.
  • Avoid excess caffeine and alcohol consumption.
  • Maintain a healthy diet and exercise regularly.
  • Practice kegel exercises to strengthen pelvic muscles.
  • Reduce stress levels by doing yoga or meditation. Nervousness can increase the frequency of urination.

Habit Forming

No

Therapeutic Class

BPH AGENTS

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

You are recommended to avoid or limit alcohol consumption while taking Zosialfa Tablet PR as it may cause increased dizziness.

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Pregnancy

Not applicable

Zosialfa Tablet PR belongs to pregnancy category B. Zosialfa Tablet PR is intended for use in men only; women should not take Zosialfa Tablet PR, especially pregnant women.

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Breast Feeding

Not applicable

Zosialfa Tablet PR is intended for use in men only; women should not take Zosialfa Tablet PR.

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Driving

Caution

Zosialfa Tablet PR may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Zosialfa Tablet PR should not be used if you have moderate to severe liver impairment. The safety of Zosialfa Tablet PR in patients with mild hepatic impairment has not been established. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Zosialfa Tablet PR should not be given to children as safety and efficacy have not been established.

FAQs

Zosialfa Tablet PR is used to treat the symptoms of benign prostatic hypertrophy.

Zosialfa Tablet PR works by relaxing the muscles of the bladder and prostate; this reduces the narrowing of the urethra. It thereby helps in relieving the symptoms of benign prostatic hyperplasia and makes it easier to pass urine.

Dry mouth could be a side effect of Zosialfa Tablet PR. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy may help stimulate saliva and thereby prevent mouth dryness.

Diarrhoea might be a side-effect of Zosialfa Tablet PR. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Orthostatic hypotension, also known as postural hypotension, could be a side-effect of Zosialfa Tablet PR. Postural hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead, lie down and get up slowly only when you feel better.

Talk to your doctor before taking Zosialfa Tablet PR with anti-fungal medicines such as ketoconazole and itraconazole, and antiretroviral medicines such as ritonavir, as they might increase the blood levels of Zosialfa Tablet PR.

Prostatic carcinoma is the cancer of the prostate gland, whereas benign prostatic hyperplasia is the non-cancerous growth of the prostate. Prostatic carcinoma and benign prostatic hyperplasia may have the same symptoms. Therefore, people with benign prostatic hyperplasia should be examined prior to starting the treatment with Zosialfa Tablet PR to rule out the presence of carcinoma of the prostate.

If you are due to have or are undergoing cataract surgery, inform the doctor that you are taking Zosialfa Tablet PR. This will help the doctor manage the complications in advance, which could occur during the surgery.

Consult your doctor before taking Zosialfa Tablet PR with nitrates. Taking Zosialfa Tablet PR with medicines used to treat angina/chest pain, such as nitrates (nitroglycerin, glyceryl trinitrate), may cause severe lowering of blood pressure.

You are advised to take Zosialfa Tablet PR for as long as your doctor has prescribed it for you, depending on your medical condition.

Yes, dizziness is a possible side effect of Zosialfa Tablet PR. If you experience it, rise slowly from a sitting or lying position and notify your doctor if the symptoms are severe or persistent.

Zosialfa Tablet PR does not shrink the prostate. It belongs to the alpha-blocker class of drugs. It works by relaxing muscles in the bladder and prostate, allowing urine to flow more freely.

No, Zosialfa Tablet PR will not cause erectile dysfunction.

It is typically taken once a day, immediately after meals. The dose and duration should be followed as directed by the physician.

Zosialfa Tablet PR should not be used if you have moderate to severe liver impairment. The safety of Zosialfa Tablet PR in patients with mild hepatic impairment has not been established. Please consult your doctor if you have a liver impairment or any concerns regarding this.

Yes, aged or elderly people can take Zosialfa Tablet PR, but they must exercise caution. Regular monitoring is essential.

While rare, Zosialfa Tablet PR can occasionally cause abnormal vision. Importantly, if you're scheduled for any eye surgery, including cataract surgery, inform your surgeon about your use of Zosialfa Tablet PR. This medication may require special considerations during the procedure

If you're taking Zosialfa Tablet PR and also plan to use sildenafil or vardenafil, don't do it without talking to your doctor first. Taking them together can cause your blood pressure to drop too low, which can be dangerous.

To help feel better while taking Zosialfa Tablet PR, follow your doctor's instructions, drink lots of water, avoid alcohol, eat healthy, get enough sleep, and tell your doctor if you have any new problems.

Common side effects of Zosialfa Tablet PR may include dizziness, nausea, vomiting, diarrhoea, stomach pain, headache, and dry mouth.

Country of origin

India
Other Info - ZO82566

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 29, 2025 | 12:42 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.3960.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021287s013lbl.pdf
  3. https://medlineplus.gov/druginfo/meds/a604002.html
  4. https://www.drugs.com/pregnancy/alfuzosin.html
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