Zycolchin Tablet 10's
MRP ₹34.5
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About Zycolchin Tablet
Zycolchin Tablet is used to prevent and treat gout attacks and relieve the pain of gout attacks. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, cardiovascular death, and needing certain types of heart procedures such as angioplasty or coronary artery bypass grafting, in patients who have atherosclerosis or who have multiple risk factors for developing heart and blood vessel disease.
Zycolchin Tablet contains Colchicine, which works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever. It helps lower the risk of heart problems and stroke by inhibiting white blood cells that cause inflammation.
In some cases, Zycolchin Tablet may cause side effects like diarrhoea, nausea, vomiting, and abdominal pain. Most of these side effects may not need medical attention and gradually resolve over time. However, if any of the side effects persist or worsen, consult your doctor.
Do not take Zycolchin Tablet if you are allergic to any of its components. Inform the doctor if you have a blood disorder, liver/kidney/heart problems, or are pregnant or breastfeeding. Zycolchin Tablet is not a pain killer and should not be used to treat pain due to other causes. Keep the doctor informed about your health conditions and medications to prevent any interactions/side effects.
Uses of Zycolchin Tablet
Prevention and treatment of gout: Zycolchin Tablet used to treat gout attacks. It is also used to prevent flare-ups of gout when treatment is started with other drugs. It stops the natural processes that cause swelling and other gout symptoms.
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Directions for Use
- Zycolchin Tablet can be taken with or without food.
- Follow the dosage and duration of treatment as advised by the doctor.
- Swallow the medicine as a whole with water.
- Do not crush, break or chew it.
Medicinal Benefits
Zycolchin Tablet is used to prevent and treat gout attacks and relieve the pain of gout attacks. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, cardiovascular death, and needing certain types of heart procedures such as angioplasty or coronary artery bypass grafting in patients who have atherosclerosis (narrowing of the blood vessels from fatty deposits) or who have multiple risk factors for developing heart and blood vessel disease. Zycolchin Tablet contains Colchicine, which works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever. It helps lower the risk of heart problems and stroke by inhibiting white blood cells that cause inflammation.
How Zycolchin Tablet Works
Storage
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Drink plenty of fluids and stay hydrated.
- Avoid foods containing sugars, salts and processed food.
- Avoid consumption of alcohol.
- Take healthy diet containing fiber, carbohydrates and lean proteins.
- Exercise regularly and maintain a healthy lifestyle.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Drink plenty of water to eliminate uric acid.
- Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
- Regularly do low impact exercises like swimming or walking.
- To reduce pain and swelling, apply ice packs to the affected area.
- Take rest and avoid activities that strain the affected joint.
- Elevate the affected joint to encourage fluid drainage.
- Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.
What if I have taken an overdose of Zycolchin Tablet
Drug Warnings
Do not take Zycolchin Tablet if you're allergic to any of its components, if you have severe blood problems, severe liver or kidney problems, or are undergoing dialysis. Consult the doctor if you are pregnant or breastfeeding. Inform the doctor if you have blood problems, kidney/liver/heart problems, or are elderly and weak. Avoid exceeding the recommended dose as it can be toxic. Do not start a new medicine without consulting the doctor. Let the doctor know if you have any other medical conditions or are taking other medicines, including supplements or herbal products.
Drug-Drug Interactions
Drug-Drug Interactions
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Coadministration of Zycolchin Tablet with itraconazole may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.
How to manage the interaction:
Zycolchin Tablet with itraconazole can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
Coadministration of Zycolchin Tablet with darunavir may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.
How to manage the interaction:
Taking Zycolchin Tablet with Darunavir is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
Using Zycolchin Tablet together with ketoconazole may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.
How to manage the interaction:
Although taking Ketoconazole with Zycolchin Tablet is not recommended as it can cause an interaction, they can be taken if prescribed by a doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without consulting a doctor
Coadministration of Zycolchin Tablet with clarithromycin may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.
How to manage the interaction:
Taking Zycolchin Tablet with Clarithromycin is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
Coadministration of Zycolchin Tablet and rosuvastatin may increase the risk of conditions that affect your muscles and kidneys.
How to manage the interaction:
Taking Zycolchin Tablet with Rosuvastatin may possibly result in an interaction, but they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience abdominal discomfort, nausea, vomiting, diarrhea, back pain, weakness, or tingling or numbness in your hands and feet. Do not discontinue any medication without consulting your doctor.
When Zycolchin Tablet is taken with Venetoclax, the amount of Zycolchin Tablet in the blood can go up.
How to manage the interaction:
Co-administration of Zycolchin Tablet with Venetoclax can result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience Stomach pain, diarrhea, nausea, and vomiting. Do not stop using any medications without a doctor's advice.
Coadministration of Zycolchin Tablet and Tamoxifen increases Zycolchin Tablet levels in the blood.
How to manage the interaction:
Although taking Zycolchin Tablet and Tamoxifentogether may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor if you experience any symptoms like nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting your doctor.
coadministration of atorvastatin with Zycolchin Tablet can increase the risk of kidney problems.
How to manage the interaction:
Co-administration of atorvastatin with Zycolchin Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, diarrhea, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet, consult the doctor. Do not stop using any medications without talking to a doctor.
Coadministration of Azithromycin with Zycolchin Tablet may raise Zycolchin Tablet levels in the blood to undesirable levels.
How to manage the interaction:
Concomitant administration of azithromycin alongside Zycolchin Tablet can result in an interaction, but it can be taken if a doctor has advised it. Inform your doctor if you have any of the following symptoms: stomach discomfort, nausea, vomiting, diarrhea, fever, muscular pain, weakness, exhaustion, and/or numbness or tingling in your hands and feet. Do not discontinue any medications without consulting a doctor.
Amprenavir may raise Zycolchin Tablet levels in the blood to unsafe levels, raising the risk of serious side effects.
How to manage the interaction:
Although taking Zycolchin Tablet and Amprenavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, contact your doctor right away. These symptoms include stomach pain, feeling sick, having diarrhoea, fever, muscle pain, feeling weak or tired, and numbness. Do not discontinue any medications without consulting your doctor.
Drug-Food Interactions
Drug-Food Interactions
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Grapefruit Juice
How to manage the interaction:
Consuming excessive quantities of grapefruit juice can raise the levels of Zycolchin Tablet in your blood, increasing the risk of side effects. Avoid the consumption of grapefruit juice while taking Zycolchin Tablet.
Diet & Lifestyle Advise
- Maintain a healthy body weight because obesity can lead to joint pain. Please avoid strenuous exercise as it may aggravate your arthritis-related joint pain. Instead, you can stretch and engage in low-impact aerobic activities such as treadmill walking, biking, and swimming. Lifting light weights can also help to improve your muscle strength.
- Increase your intake of glucosamine, chondroitin sulphate, vitamin D, and calcium-rich supplements. Aside from that, turmeric and fish oils can help to reduce tissue inflammation.
- Include fish such as salmon, trout, tuna, and sardines in your diet if you have arthritis or joint pain. These fish are high in omega-3 fatty acids, which aid in the reduction of inflammation (redness and swelling) and the protection of the heart.
- Your sitting posture is critical, especially if you suffer from pain or inflammation. Try to sit as little as possible and only for a short period of time (10-15 min). Place a rolled-up towel at the back of your curve to alleviate pain. In addition, if necessary, a footrest can be used.
- Follow heat or cold therapy by regularly applying a cold or hot compress to the joints for 15-20 minutes.
- Relax by meditating, reading, enjoying a bubble bath, or listening to calming music.
- Avoid drinking alcohol and quitting smoking.
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Alcohol
Consult your doctor
It is not known if alcohol interacts with Zycolchin Tablet . Please consult the doctor.
Pregnancy
Caution
Please consult the doctor if you are pregnant, as it is not known if colchicine will harm the unborn baby.
Breast Feeding
Caution
Colchicine may pass into breastmilk. Please consult the doctor if you are breastfeeding.
Driving
Caution
Zycolchin Tablet may cause dizziness. Therefor, drive or operate machinery only if you are alert.
Liver
Caution
Zycolchin Tablet is not recommended for people with severe liver problems. Please consult the doctor if you have liver impairment or any concerns regarding this.
Kidney
Caution
Zycolchin Tablet is not recommended for people with severe kidney problems. Please consult the doctor if you have kidney impairment or any concerns regarding this.
Children
Caution
Zycolchin Tablet should be used in children below 12 years only when prescribed by a child specialist.
Heart
Zycolchin Tablet can be used in heart patients if prescribed by the physician to reduce cardiovascular problems. Please consult your physician if you have any concerns.
Geriatrics
Caution
Geriatric patients can take Zycolchin Tablet under extreme caution if prescribed by the physician. It's important to use it under close medical supervision with tailored dosing and regular monitoring.
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Reference
- https://medlineplus.gov/druginfo/meds/a682711.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/215727s000lbl.pdf
- https://www.medicines.org.uk/emc/files/pil.6415.pdf
- https://www.accord-healthcare.com/ie/system/files/pil/colchicine_tiofarma_500_and_1000_microgram_tablets_pil_20200515_clean.pdf
- https://patient.info/medicine/colchicine-for-gout-attacks
