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  3. Zycolchin Tablet 10's

Zycolchin Tablet 10's, Pack of 10 TABLETS
Zycolchin Tablet 10's, Pack of 10 TABLETS
Zycolchin Tablet 10's, Pack of 10 TABLETS
Zycolchin Tablet 10's, Pack of 10 TABLETS
Zycolchin Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zycolchin Tablet is used to prevent and treat gout attacks and relieve the pain of gout attacks. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, and cardiovascular death. It works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever. This medicine may cause side effects such as diarrhoea, nausea, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

COLCHICINE-0.5MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Zycolchin Tablet

Zycolchin Tablet is used to prevent and treat gout attacks and relieve the pain of gout attacks. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, cardiovascular death, and needing certain types of heart procedures such as angioplasty or coronary artery bypass grafting, in patients who have atherosclerosis or who have multiple risk factors for developing heart and blood vessel disease.

Zycolchin Tablet contains Colchicine, which works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever. It helps lower the risk of heart problems and stroke by inhibiting white blood cells that cause inflammation.

In some cases, Zycolchin Tablet may cause side effects like diarrhoea, nausea, vomiting, and abdominal pain. Most of these side effects may not need medical attention and gradually resolve over time. However, if any of the side effects persist or worsen, consult your doctor.

Do not take Zycolchin Tablet if you are allergic to any of its components. Inform the doctor if you have a blood disorder, liver/kidney/heart problems, or are pregnant or breastfeeding. Zycolchin Tablet is not a pain killer and should not be used to treat pain due to other causes. Keep the doctor informed about your health conditions and medications to prevent any interactions/side effects.

Uses of Zycolchin Tablet

Prevention and treatment of gout: Zycolchin Tablet used to treat gout attacks. It is also used to prevent flare-ups of gout when treatment is started with other drugs. It stops the natural processes that cause swelling and other gout symptoms.<br/>Treatment of familial Mediterranean fever: Colchicine is also used to treat familial Mediterranean fever in adults and children 4 years of age and older. It prevents fever attacks and amyloidosis (abnormal precipitation of proteins in tissues and organs).<br/>Lowering the risk of heart attack/stroke: Colchicine is also used to reduce the risk of heart attack, stroke, cardiovascular death, and needing certain types of heart procedures such as angioplasty or coronary artery bypass grafting in patients who have atherosclerosis (narrowing of the blood vessels from fatty deposits) or who have multiple risk factors for developing heart and blood vessel disease.

Directions for Use

  • Zycolchin Tablet can be taken with or without food.
  • Follow the dosage and duration of treatment as advised by the doctor.
  • Swallow the medicine as a whole with water.
  • Do not crush, break or chew it.

Medicinal Benefits

Zycolchin Tablet is used to prevent and treat gout attacks and relieve the pain of gout attacks. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, cardiovascular death, and needing certain types of heart procedures such as angioplasty or coronary artery bypass grafting in patients who have atherosclerosis (narrowing of the blood vessels from fatty deposits) or who have multiple risk factors for developing heart and blood vessel disease. Zycolchin Tablet contains Colchicine, which works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever. It helps lower the risk of heart problems and stroke by inhibiting white blood cells that cause inflammation.

How Zycolchin Tablet Works

Zycolchin Tablet contains Colchicine, which works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zycolchin Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink plenty of fluids and stay hydrated.
  • Avoid foods containing sugars, salts and processed food.
  • Avoid consumption of alcohol.
  • Take healthy diet containing fiber, carbohydrates and lean proteins.
  • Exercise regularly and maintain a healthy lifestyle.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.

What if I have taken an overdose of Zycolchin Tablet

Do not take more than the prescribed dose of Zycolchin Tablet as it may cause an overdose. The symptoms of overdose include nausea, vomiting, diarrhoea, stomach pain, slowed breathing, sore throat/fever/chills and other signs of infection, unusual bruising or bleeding, paleness or greyness of the lips/tongue/palms and slowed heartbeat. If you suspect you have taken an overdose or notice any symptoms of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Zycolchin Tablet if you're allergic to any of its components, if you have severe blood problems, severe liver or kidney problems, or are undergoing dialysis. Consult the doctor if you are pregnant or breastfeeding. Inform the doctor if you have blood problems, kidney/liver/heart problems, or are elderly and weak. Avoid exceeding the recommended dose as it can be toxic. Do not start a new medicine without consulting the doctor. Let the doctor know if you have any other medical conditions or are taking other medicines, including supplements or herbal products.

Drug-Drug Interactions

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ColchicineDarunavir
Critical
ColchicineKetoconazole
Critical

Drug-Drug Interactions

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ColchicineDarunavir
Critical
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet with darunavir may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Taking Zycolchin Tablet with Darunavir is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ColchicineKetoconazole
Critical
How does the drug interact with Zycolchin Tablet:
Using Zycolchin Tablet together with ketoconazole may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Ketoconazole with Zycolchin Tablet is not recommended as it can cause an interaction, they can be taken if prescribed by a doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without consulting a doctor
ColchicineItraconazole
Critical
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet with itraconazole may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Zycolchin Tablet with itraconazole can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ColchicineClarithromycin
Critical
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet with clarithromycin may increase the blood levels of Zycolchin Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Taking Zycolchin Tablet with Clarithromycin is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ColchicineAmiodarone
Severe
How does the drug interact with Zycolchin Tablet:
Coadministration of amiodarone with Zycolchin Tablet may increase the Zycolchin Tablet levels, leading to an increased risk or severity of side effects.

How to manage the interaction:
Taking amiodarone and Zycolchin Tablet together can lead to an interaction, but they can be taken together if your doctor has advised it. However, consult a doctor if you experience abdominal discomfort, diarrhoea, fever, muscle pain, tiredness, weakness, and numbness or tingling in your hands and feet. Do not discontinue any medications without consulting a doctor.
ColchicineAmprenavir
Severe
How does the drug interact with Zycolchin Tablet:
Amprenavir may raise Zycolchin Tablet levels in the blood to unsafe levels, raising the risk of serious side effects.

How to manage the interaction:
Although taking Zycolchin Tablet and Amprenavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, contact your doctor right away. These symptoms include stomach pain, feeling sick, having diarrhoea, fever, muscle pain, feeling weak or tired, and numbness. Do not discontinue any medications without consulting your doctor.
ColchicineAzithromycin
Severe
How does the drug interact with Zycolchin Tablet:
Coadministration of Azithromycin with Zycolchin Tablet may raise Zycolchin Tablet levels in the blood to undesirable levels.

How to manage the interaction:
Concomitant administration of azithromycin alongside Zycolchin Tablet can result in an interaction, but it can be taken if a doctor has advised it. Inform your doctor if you have any of the following symptoms: stomach discomfort, nausea, vomiting, diarrhea, fever, muscular pain, weakness, exhaustion, and/or numbness or tingling in your hands and feet. Do not discontinue any medications without consulting a doctor.
ColchicineCeritinib
Severe
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet with Ceritinib results in increased Zycolchin Tablet levels in the blood.

How to manage the interaction:
Although taking Zycolchin Tablet and Ceritinib together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.
ColchicinePitavastatin
Severe
How does the drug interact with Zycolchin Tablet:
Coadministration of Zycolchin Tablet and pitavastatin may increase the risk of conditions.

How to manage the interaction:
Taking Zycolchin Tablet with pitavastatin may possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience abdominal discomfort, nausea, vomiting, diarrhea, back pain, weakness, or tingling or numbness in your hands and feet. Do not discontinue any medication without consulting a doctor.
ColchicinePosaconazole
Severe
How does the drug interact with Zycolchin Tablet:
Co-administration of Zycolchin Tablet with posaconazole resulted in elevated Zycolchin Tablet levels in the blood. This can lead to increased side effects from Zycolchin Tablet.

How to manage the interaction:
Although taking Zycolchin Tablet and Posaconazole together may result in an interaction, they can be taken together if your doctor prescribes it. However, if you experience abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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COLCHICINE-0.5MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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COLCHICINE-0.5MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming excessive quantities of grapefruit juice can raise the levels of Zycolchin Tablet in your blood, increasing the risk of side effects. Avoid the consumption of grapefruit juice while taking Zycolchin Tablet.

Diet & Lifestyle Advise

  • Maintain a healthy body weight because obesity can lead to joint pain. Please avoid strenuous exercise as it may aggravate your arthritis-related joint pain. Instead, you can stretch and engage in low-impact aerobic activities such as treadmill walking, biking, and swimming. Lifting light weights can also help to improve your muscle strength.
  • Increase your intake of glucosamine, chondroitin sulphate, vitamin D, and calcium-rich supplements. Aside from that, turmeric and fish oils can help to reduce tissue inflammation.
  • Include fish such as salmon, trout, tuna, and sardines in your diet if you have arthritis or joint pain. These fish are high in omega-3 fatty acids, which aid in the reduction of inflammation (redness and swelling) and the protection of the heart.
  • Your sitting posture is critical, especially if you suffer from pain or inflammation. Try to sit as little as possible and only for a short period of time (10-15 min). Place a rolled-up towel at the back of your curve to alleviate pain. In addition, if necessary, a footrest can be used.
  • Follow heat or cold therapy by regularly applying a cold or hot compress to the joints for 15-20 minutes.
  • Relax by meditating, reading, enjoying a bubble bath, or listening to calming music.
  • Avoid drinking alcohol and quitting smoking.

Habit Forming

No

Therapeutic Class

ANTI- GOUT MEDICATIONS

Zycolchin Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is not known if alcohol interacts with Zycolchin Tablet . Please consult the doctor.

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Pregnancy

Caution

Please consult the doctor if you are pregnant, as it is not known if colchicine will harm the unborn baby.

bannner image

Breast Feeding

Caution

Colchicine may pass into breastmilk. Please consult the doctor if you are breastfeeding.

bannner image

Driving

Caution

Zycolchin Tablet may cause dizziness. Therefor, drive or operate machinery only if you are alert.

bannner image

Liver

Caution

Zycolchin Tablet is not recommended for people with severe liver problems. Please consult the doctor if you have liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Zycolchin Tablet is not recommended for people with severe kidney problems. Please consult the doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Zycolchin Tablet should be used in children below 12 years only when prescribed by a child specialist.

Have a query?

FAQs

Zycolchin Tablet is used to treat and prevent acute attacks or flare-ups of gout. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, and cardiovascular death in patients who have or who have multiple risk factors for developing heart and blood vessel disease.

Zycolchin Tablet works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever.

Zycolchin Tablet is usually prescribed for a short period of time. Consult the doctor if your condition persists or worsens; the doctor may prescribe an alternate medicine.

No, do not exceed the recommended dosage as it will not help treat your condition faster. Avoid exceeding the recommended dose as colchicine can be toxic. Take Zycolchin Tablet only as prescribed by the doctor.

Do not stop taking Zycolchin Tablet without consulting the doctor. To treat your condition effectively, take Zycolchin Tablet for as long as it has been prescribed by the doctor.

Zycolchin Tablet may cause blood problems like such as myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, and aplastic anaemia. Consult the doctor if you notice pale or grey colour lips, tongue, or palms; unusual bleeding or bruising; feel weak or tired; or increased infections.

The early symptoms the patient can identify if he/she is suffering from gout include sudden and intense pain in a joint, often the big toe. The area can become red, warm, swollen, and tender, making moving difficult. These symptoms usually appear suddenly, especially at night. If you notice these signs, seeing a doctor for suitable care and preventing acute attacks is essential.

Zycolchin Tablet may cause muscle problems. Seek medical attention if you experience muscle pain, weakness, numbness or tingling sensation.

Diarrhea is the most frequently reported side effect associated with Zycolchin Tablet . If you experience severe or worsening diarrhoea, notify your doctor to receive guidance on managing diarrhoea. But, do not self-medicate with loperamide or any other anti-diarrheal medication without consulting a doctor, as this may interfere with Zycolchin Tablet efficacy or may lead to potential interactions.

Never split medication tablets unless your doctor advises. This ensures accurate dosing and prevents potential complications. Consult your healthcare provider or pharmacist before splitting any medication.

Yes, like all medications, Zycolchin Tablet also expires. Before using the Zycolchin Tablet , always verify the expiration date printed on the packaging. Never take expired Zycolchin Tablet to avoid negative complications. Consult a doctor or pharmacist to get fresh medication.

Zycolchin Tablet is not intended to cause weight loss. Due to the underlying condition being treated and common side effects of Zycolchin Tablet , such as weakness, may lead to slight weight loss. However, this symptom vanishes over time. If you're concerned about weight changes while taking Zycolchin Tablet , consult your healthcare provider for personalized guidance.

Hair loss is not a common side effect of Zycolchin Tablet . Suppose you experience hair loss or thinning while taking Zycolchin Tablet . In that case, it's best to consult a doctor to determine the reason for the hair loss and discuss possible alternatives or solutions.

Zycolchin Tablet is not typically known to raise blood sugar levels. However, individual responses to medication can vary. If you have concerns about your blood sugar while taking Zycolchin Tablet , inform your doctor. They may undergo a glucose level monitoring program and consult their doctor for personalized advice.

Yes, Zycolchin Tablet may increase liver damage risk, especially for those with liver issues or taking liver-affecting medications. Before taking Zycolchin Tablet , inform the doctor about any pre-existing liver conditions and current medications. The doctor will provide personalized guidance, as caution is advised for patients with regular liver function monitoring is crucial while on Colchicine.

The common side effects of the Zycolchin Tablet that usually occur while using it are nausea, vomiting, diarrhoea, abdominal pain, and fatigue. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

If you forget a dose of Zycolchin Tablet , take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - ZYC0005

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:36 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://medlineplus.gov/druginfo/meds/a682711.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/215727s000lbl.pdf
  3. https://www.medicines.org.uk/emc/files/pil.6415.pdf
  4. https://www.accord-healthcare.com/ie/system/files/pil/colchicine_tiofarma_500_and_1000_microgram_tablets_pil_20200515_clean.pdf
  5. https://patient.info/medicine/colchicine-for-gout-attacks

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