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More about the Product

Composition :

LINEZOLID-600MG

Manufacturer/Marketer :

Leeford Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Zydolid Tablet

Zydolid Tablet is used to treat bacterial infections of the lungs (pneumonia), skin and soft tissues. It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body.

Zydolid Tablet contains Linezolid, which inhibits bacterial protein synthesis, thereby killing the bacteria.

You may experience common side effects, such as headache, a metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Do not take Zydolid Tablet on your own, as it may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections. Consult your doctor if you are pregnant or planning to become pregnant before taking Zydolid Tablet .

Uses of Zydolid Tablet

Zydolid Tablet is used in the treatment of bacterial infections caused by Gram-positive bacteria. The detailed uses of Zydolid Tablet are as follows:

  • Pneumonia (Lung Infection): Zydolid Tablet is effective in treating both community-acquired and hospital-acquired pneumonia caused by susceptible bacteria.
  • Skin and Skin Structure Infections: Zydolid Tablet is used to treat mild to severe bacterial infections of the skin and its underlying tissues. It is also indicated for the treatment of diabetic foot infections, without associated bone infections (osteomyelitis).
  • Antibiotic-Resistant Infections: Zydolid Tablet is indicated for infections caused by the bacteria Enterococcus faecium that are resistant to vancomycin, including intra-abdominal infections, skin and soft tissue infections, urinary tract infections, and concurrent bacteremia (presence of bacteria in the bloodstream).

Key Benefits

For Pneumonia:

  • Cures pneumonia brought on by resistant gram-positive bacteria.
  • Beneficial for ventilator-associated pneumonia and pneumonia acquired in hospitals.
  • Relieves the symptoms of infection, breathing and fever when other antibiotics are ineffective.
  • Ideal for people who don't react to or can't handle other antibiotics.

For soft skin structures:

  • Beneficial for complex soft tissue and skin infections, such as cellulitis, abscesses, and wound infections.
  • Ensures efficient infection control by having good penetration into soft tissues and skin.
  • Aids in lowering infection-related discomfort, redness, swelling, and pus production.

For Vancomycin-resistant enterococcal infections

  • Beneficial for severe infections include bloodstream infections, intra-abdominal infections, and complex Vancomycin-resistant enterococcal infections.
  • When other antibiotics are ineffective or poorly tolerated, it helps patients achieve better clinical results.

Directions for Use

  • Zydolid Tablet can be taken with or without food, as advised by your doctor.
  • Your doctor will decide the appropriate dosage and timing based on your medical condition.
  • Swallow Zydolid Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.

How Zydolid Tablet Works

Zydolid Tablet contains Linezolid (an antibiotic), which works by stopping the bacteria from making proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Zydolid Tablet , as it may cause increased dizziness.

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Pregnancy

Consult your doctor

Zydolid Tablet belongs to pregnancy category C. If you are pregnant, please consult your doctor before using Zydolid Tablet . Your doctor will prescribe it only if the potential benefits justify the possible risks.

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Breast Feeding

Unsafe

Avoid taking Zydolid Tablet if you are breastfeeding, as it may pass into breast milk and cause harmful effects in the baby.

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Driving

Caution

Zydolid Tablet may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be necessary if you have liver impairment or disease. Please consult your doctor to discuss any concerns or to ensure safe and appropriate use.

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Kidney

Caution

Dose adjustment may be necessary if you have kidney impairment or disease. Please consult your doctor to discuss any concerns or to ensure safe and appropriate use.

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Children

Unsafe

Zydolid Tablet is not recommended for children below 18 years of age.

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Heart

Caution

Zydolid Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Zydolid Tablet to geriatric patients. Your doctor will prescribe Zydolid Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Zydolid Tablet

Do not take more than the prescribed dose of Zydolid Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

Eating changes:

  • Avoid foods like salami, smoked meats, red wine, beer, pickles, soy sauce, aged cheeses, and fermented foods.
  • Consume foods that are newly cooked rather than ones that are aged or preserved.
  • Eat a diet rich in fruits, vegetables, whole grains, and lean meats to stay balanced.

Physical activity:

  • As tolerated, engage in mild-to-moderate exercise, such as walking or gentle stretching.
  • Ensure adequate sleep to support the healing process after an infection.

Environment changes:

  • To reduce the risk of developing or worsening infections, stay in a clean, well-ventilated environment.
  • Avoid dusty or congested areas, particularly during treatment for severe diseases.
  • Keep your house and workplace clean and practice good hand hygiene.

Stress management:

  • To manage stress and blood pressure, engage in mindfulness, meditation, or deep breathing exercises.
  • To lessen mental stress, get emotional support from friends or family.

Have a query?

How Soon It Starts Working

  • The time required for Zydolid Tablet to start to work: Zydolid Tablet ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of Zydolid Tablet last: The effect of Zydolid Tablet lasts for 12 to 15 hours.

What if you forget to take Zydolid Tablet

If you miss a dose of Zydolid Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you are unsure what to do, please consult your doctor or pharmacist.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Zydolid Tablet if you are allergic to any of its contents or if you are taking or have taken monoamine oxidase (MAO-antidepressants) inhibitors in the last 14 days.
  • Talk to your doctor if you have high blood pressure, an overactive thyroid, phaeochromocytoma (tumour of adrenal glands), carcinoid syndrome (tumours of the hormone system), manic depression, schizophrenia, confusion, or other mental problems.
  • Consult your doctor if you are pregnant before taking Zydolid Tablet .
  • Zydolid Tablet passes into breastmilk, so do not take Zydolid Tablet if you are breastfeeding.
  • Zydolid Tablet may cause dizziness and vision problems; therefore, exercise caution when driving and operating machinery.

Drug-Drug Interactions

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Drug-Drug Interactions: Inform your doctor if you are taking any of these medicines, as there may be an interaction.

  • Antidepressant drugs (citalopram, amitriptyline)
    Potential effect: May increase the risk of side effects like agitation, confusion, increased blood pressure, and tremors.
  • Antiallergic drugs (epinephrine)
    • Potential effect: May increase the effects of elevated blood pressure
  • Antimigraine medications (sumatriptan)
    Potential effect: May increase the risk of serotonin syndrome (a medical condition which occurs due to high levels of serotonin intake)

Drug-Food Interactions: Avoid foods and drinks containing tyramine, such as cheese, yeast extracts, soybean extracts, alcohol, beer, or wine while taking Zydolid Tablet , as it may interact with tyramine and lead to an increase in blood pressure.

Drug-Disease Interactions: Inform your doctor if you have a history of the following conditions before taking Zydolid Tablet , as it may worsen your condition or cause complications.

  • Colitis (inflammation in the lining of the colon)
  • Seizures
  • High blood pressure
  • Hypoglycaemia (low blood sugar levels)
  • Kidney or liver disease.

Drug-Drug Interactions

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How does the drug interact with Zydolid Tablet:
Taking Zydolid Tablet with Amitriptyline can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Zydolid Tablet and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zydolid Tablet:
When Vilazodone is taken with Zydolid Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vilazodone with Zydolid Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
LinezolidCaffeine
Critical
How does the drug interact with Zydolid Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Caffeine with Zydolid Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Zydolid Tablet:
Using Zydolid Tablet together with Paroxetine can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).

How to manage the interaction:
Taking Paroxetine with Zydolid Tablet is not recommended but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zydolid Tablet:
Using Carbamazepine with Zydolid Tablet can cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Carbamazepine and Zydolid Tablet together is not recommended, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zydolid Tablet:
Using Zydolid Tablet together with atomoxetine can cause high blood pressure.

How to manage the interaction:
Taking Zydolid Tablet with Atomoxetine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zydolid Tablet:
Coadministration of Zydolid Tablet with Imipramine might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Zydolid Tablet and Imipramine together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zydolid Tablet:
Taking Zydolid Tablet with Fentanyl may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Zydolid Tablet and Fentanyl, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Zydolid Tablet:
Taking Zydolid Tablet with Epinephrine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Zydolid Tablet with Epinephrine is not recommended as it can result in an interaction. It should be taken only if a doctor has advised it. However, if you experience confusion, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zydolid Tablet:
Taking Zydolid Tablet with Methylphenidate together may increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Zydolid Tablet with Methylphenidate is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden and severe headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, contact a doctor immediately. You may use methylphenidate only after you have been off Zydolid Tablet for at least 14 days. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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LINEZOLID-600MGTyramine-containing food
Severe

Drug-Food Interactions

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LINEZOLID-600MGTyramine-containing food
Severe
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Taking high tyramine-containing food along with Zydolid Tablet can cause blood pressure to rise to exceedingly high levels, a condition known as a hypertensive crisis (Severely elevated blood pressure). Avoid high tyramine-containing food while taking Zydolid Tablet. Consult a doctor, if you experience severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body).

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Zydolid Tablet is an antibiotic medication used to treat bacterial infections of the skin and lungs (pneumonia). It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections.

Zydolid Tablet contains Linezolid (an antibiotic), which works by stopping the bacteria from making proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.

Diarrhoea might be a side effect of Zydolid Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have prolonged diarrhoea with abdominal pain, stop taking Zydolid Tablet and consult your doctor. Do not take anti-diarrheal medicine on your own.

It is recommended to complete the course of Zydolid Tablet even if you feel better, as it is an antibiotic, and leaving it in between may lead to even more severe infection. To treat your condition effectively, continue taking Zydolid Tablet for as long as your doctor has prescribed it.

Zydolid Tablet may cause thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Do not take Zydolid Tablet on your own, as self-medication may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections.

Zydolid Tablet may affect certain laboratory test results, such as blood tests, blood sugar tests, and liver and kidney function tests. Inform the person doing the tests that you are taking Zydolid Tablet .

Zydolid Tablet may cause anaemia due to a decrease in the number of red blood cells. This could also cause unexplained bleeding or bruising. Consult your doctor if you experience unexplained bleeding or bruising.

Consult your doctor before taking Zydolid Tablet if you have hypertension (high blood pressure), as it may cause an increase in blood pressure.

You should avoid taking large quantities of food that contains high tyramine. Foods that are fermented, cured, aged or spoiled contain a high amount of tyramine, e.g. cheese, red wine, pickles, overripe fruits, etc. Consuming tyramine while taking Linezolid can result in an elevation of blood pressure, which may result in an emergency.

You should take it twice a day, every 12 hours, for example, at 8 a.m. and 8 p.m. You can take it before, with, or after food. Your doctor or clinician will determine the duration of the treatment course.

Zydolid Tablet is indicated for the treatment of gram-positive infections and is approved for treating skin and skin structure infections, bacterial pneumonia, and vancomycin-resistant enterococcal (VRE) infections, including those complicated by bacteremia.

It is usually taken with or without food or as directed by the doctor.

Common side effects of Zydolid Tablet may include thrush (fungal infection), headache, metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please consult your doctor. Zydolid Tablet should be used during pregnancy or breastfeeding only if needed, and the benefit outweighs the risk to the fetus.

Avoid consuming alcohol while taking Zydolid Tablet , as it may cause increased dizziness.

Take the missed dose as soon as you remember, unless it is almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

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Country of origin

India

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116.
Other Info - ZYD0030
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