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Zymmune 100mg/ml Injection is used to prevent rejection of transplanted organs. It contains cyclosporine, which works by suppressing the body’s immune system. This medicine may cause side effects like nausea, vomiting, headache, and abdominal pain. Inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Zymmune 100mg/ml Injection

Zymmune 100mg/ml Injection belongs to the class of medicines called immunosuppressants, used to prevent organ rejection after a transplant. It may also be indicated in autoimmune conditions like psoriasis and rheumatoid arthritis.

Zymmune 100mg/ml Injection contains cyclosporine, which works by suppressing the immune response. Thereby, it helps to prevent organ rejection.

Zymmune 100mg/ml Injection may cause side effects like nausea, vomiting, headache, and abdominal pain. Talk to your doctor if any of the side effects persist or worsen.

Let your doctor know about your medical condition and the medications you are taking to avoid potential interactions. Inform your doctor if you are pregnant or breastfeeding.

Uses of Zymmune 100mg/ml Injection

Zymmune 100mg/ml Injection is primarily used to prevent transplant rejection. The detailed uses of Zymmune 100mg/ml Injection are as follows:

  • Prevention of organ rejection: Zymmune 100mg/ml Injection prevents graft rejection after transplants, such as kidney, liver, and heart transplants.
  • Manage graft-versus-host disease (GVHD): Used after bone marrow or stem cell transplants to prevent and treat GVHD, a condition where donor cells attack the recipient's tissues.
  • Autoimmune conditions: Treat autoimmune diseases such as rheumatoid arthritis, psoriasis, lupus, and nephrotic syndrome.

Key Benefits

  • Zymmune 100mg/ml Injection helps prevent graft rejection in patients undergoing solid organ transplants, such as kidney, liver, heart, and lung transplants.
  • It promotes long-term survival and function of the transplanted organ by suppressing the immune system.
  • It is used to manage and reverse cellular rejection episodes in transplant recipients who were previously on other immunosuppressive therapies.
  • Zymmune 100mg/ml Injection prevents graft rejection in patients receiving allogeneic bone marrow or stem cell transplants.
  • It plays a critical role in preventing and treating graft-versus-host disease (GVHD), a serious complication where donor immune cells attack the recipient’s body.
  • Cyclosporine works by selectively inhibiting the activation of T-lymphocytes, key players in the immune response, thereby reducing the risk of tissue rejection.
  • It ensures a more stable post-transplant period and improves overall transplant success rates.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Zymmune 100mg/ml Injection will be administered by a doctor or nurse in a healthcare facility.
  • Do not self-administer.

How Zymmune 100mg/ml Injection Works

Zymmune 100mg/ml Injection contains cyclosporine, which works by blocking the development of specific cells that usually attack the transplanted tissue. Thus, it helps to prevent organ rejection.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Zymmune 100mg/ml Injection. It could lead to an increase in adverse events.

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Pregnancy

Caution

In general, Zymmune 100mg/ml Injection should not be taken during pregnancy. If it is necessary for you to use this medicine, your doctor will discuss with you the benefits and potential risks of taking it during pregnancy.

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Breast Feeding

Unsafe

Breastfeeding is not recommended while taking Zymmune 100mg/ml Injection.

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Driving

Caution

Zymmune 100mg/ml Injection may cause sleepiness, disorientation, or blurred vision. Drive and operate machinery only if you are alert.

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Liver

Caution

Inform your doctor before receiving Zymmune 100mg/ml Injection if you have a pre-existing or a history of liver disease. Your doctor will prescribe it only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving Zymmune 100mg/ml Injection if you have a pre-existing or a history of kidney disease. Your doctor will prescribe it only if the benefits outweigh the risks.

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Children

Unsafe

Zymmune 100mg/ml Injection is not recommended for children as efficacy and safety have not been established.

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Heart

Caution

Zymmune 100mg/ml Injection should be used with caution in patients with heart problems. Therefore, please inform your doctor if your have any heart problems before prescribing Zymmune 100mg/ml Injection.

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Geriatrics

Caution

Zymmune 100mg/ml Injection should be used under medical supervision in geriatric patients due to increased risk of side effects. Therefore, please consult your doctor before using Zymmune 100mg/ml Injection.

What if I have taken an overdose of Zymmune 100mg/ml Injection

As Zymmune 100mg/ml Injection is a parenteral formulation, the chance of overdose may be less. In case of overdose, patients must be closely monitored for signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted.

Diet & Lifestyle Advise

  • Eat a low-sodium diet to help manage high blood pressure.
  • Focus on whole, unprocessed foods like vegetables, fruits, and whole grains.
  • Stay hydrated by drinking plenty of water (at least 8-10 glasses daily).
  • Avoid grapefruit and grapefruit juice as they can interact with Cyclosporine Injection.
  • Exercise regularly, aiming for at least 30 minutes of moderate-intensity exercise per day.
  • Get enough sleep, aiming for 7-8 hours per night.
  • Manage stress through techniques like meditation, deep breathing, or yoga.
  • Avoid smoking and secondhand smoke to reduce the risk of infection.
  • Limit alcohol consumption.
  • Regularly monitor your blood pressure and kidney function with your doctor's guidance.

Have a query?

How Soon It Starts Working

The time required for Zymmune 100mg/ml Injection to start to work: The time required for Zymmune 100mg/ml Injection to show its action is unknown. The time for which the effects of Zymmune 100mg/ml Injection last: The duration of action for Zymmune 100mg/ml Injection is unknown.

What if you forget to take Zymmune 100mg/ml Injection

If you miss a dose of Zymmune 100mg/ml Injection, contact your doctor immediately to schedule a new injection.

Storage

• Store in a cool and dry place away from sunlight.• Keep Zymmune 100mg/ml Injection out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not receive Zymmune 100mg/ml Injection if you are allergic to any of its components.
  • Inform your doctor if you have liver or kidney problems, high blood pressure, high lipid levels, low magnesium levels, high potassium levels, high uric acid levels or if you are due to undergo vaccinations.
  • If you are pregnant or breastfeeding, inform your doctor before receiving Zymmune 100mg/ml Injection.
  • Zymmune 100mg/ml Injection may cause sleepiness, disorientation, or blurred vision. Drive and operate machinery only if you are alert.
  • Let your doctor know about all your medical conditions, sensitivities, and all medications (including herbal and supplement products) you are using.

verifiedApollotooltip

Drug-Drug Interactions: Zymmune 100mg/ml Injection may have interactions with certain Immunosuppressants (mycophenolate mofetil, methotrexate), potassium-sparing diuretics (spironolactone), antibiotics (erythromycin, azithromycin), antifungals (voriconazole, itraconazole), medicines used for heart problems or high blood pressure (diltiazem, amiodarone, nicardipine, verapamil), anti-convulsant medicines (carbamazepine, phenytoine) and pain killers (diclofenac).

Drug-Food Interactions: Avoid alcoholic beverages, grapefruit or grapefruit juice while taking Zymmune 100mg/ml Injection.

Drug-Disease Interactions: If you have a history of high blood pressure, liver or kidney disease, infections, electrolyte imbalance, or gout, inform your doctor before starting treatment.

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Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS]

FAQs

Zymmune 100mg/ml Injection belongs to the class of medicines called immunosuppressants, used to prevent organ rejection after a transplant.

Zymmune 100mg/ml Injection works by suppressing the body's immune system, preventing it from attacking the transplanted organ. It does this by blocking the production of certain cells that usually attack the transplanted tissue.

The side effects of Zymmune 100mg/ml Injection include kidney problems, high blood pressure, headaches, tremors, excessive hair growth, and elevated lipid levels.

Zymmune 100mg/ml Injection may cause high blood pressure. If you experience this side effect, monitoring your blood pressure regularly and following a healthy lifestyle are essential. This includes eating a balanced diet low in sodium and fat, exercising regularly, reducing stress, and taking any prescribed medication as directed. Working closely with your healthcare provider is crucial to managing high blood pressure and adjusting your treatment plan as needed.

If you're already taking blood pressure medication, consult your doctor before starting Cyclosporine Injection, as it may increase blood pressure. Your doctor will advise on safe usage.

Zymmune 100mg/ml Injection belongs to a class of medications called Immunosuppressants.

Yes, grapefruit and grapefruit juice can interact with Zymmune 100mg/ml Injection. Avoid consuming grapefruit or grapefruit juice while taking Zymmune 100mg/ml Injection.

Yes, in rare cases, Zymmune 100mg/ml Injection may cause allergic reactions. Seek medical attention immediately if you experience hives, itching, or difficulty breathing.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Manufacturer/Marketer address

Instant Remedies Pvt. Ltd., Plot No. 177, Industrial Area Phase II, Opposite to Platinum Honda, Industrial Area Phase II, Chandigarh, 160002, India
Other Info - ZY46032
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