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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Osto Polybion D Syrup is a combination medicine primarily used to treat nutritional deficiencies, low calcium levels, osteoporosis, vitamin D deficiency, vitamin B12 deficiency, osteomalacia/rickets, hypoparathyroidism, and latent tetany. This medicine works by increasing the calcium and vitamin D levels in the body and regulates bodily functions, thus providing essential nutrients necessary for bone formation and maintenance. Common side effects include constipation, stomach upset, nausea, vomiting, loss of appetite, weakness, tiredness, and headache.

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Manufacturer/Marketer :

Merck Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Osto Polybion D Syrup

Osto Polybion D Syrup belongs to the class of 'Vitamins', primarily used to treat nutritional deficiencies. Osto Polybion D Syrup effectively treats various conditions caused by low calcium levels in the body like Vitamin D deficiency, vitamin B12 deficiency, osteoporosis (weak and brittle bones), hypoparathyroidism (parathyroid glands make low levels of calcium in the body), latent tetany (a muscle disease with low blood calcium levels), and rickets or osteomalacia (softening or deforming of bones due to lack of calcium). Nutritional deficiency occurs when the body is unable to absorb or get enough nutrients from food. It could lead to various health problems, including defective bone growth, skin disorders, digestive issues, and dementia (memory loss).

Osto Polybion D Syrup consists of three medicines: Elemental Calcium, Vitamin D3 (Cholecalciferol), and Cyanocobalamin. Elemental Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation. Vitamin D3 is a steroid hormone produced in the skin when exposed to ultraviolet light or obtained from food sources. It helps maintain blood calcium and phosphorus levels and mineralization of bone. Cyanocobalamin is a form of vitamin B12 that helps in the proper functioning of the brain, nerves, and red blood cells.

Your doctor will decide the dosage based on your medical condition. Osto Polybion D Syrup is likely safe to consume. In some cases, it may cause side effects like diarrhoea, constipation, and stomach upset. These side effects do not require medical attention and gradually resolve over time.

Let your doctor know if you are using any other medicines and herbal products before starting Osto Polybion D Syrup . Please inform your doctor if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), malabsorption syndrome (difficulty absorbing nutrition from food), low levels of bile, and phosphate imbalance before starting Osto Polybion D Syrup . Pregnant or breastfeeding women should consult their doctor before taking Osto Polybion D Syrup . Osto Polybion D Syrup is safe to use in children only when advised by the doctor. 

Uses of Osto Polybion D Syrup

Treatment of Vitamin D deficiency, Vitamin B12 deficiency, Osteoporosis, Osteomalacia (Rickets), Hypoparathyroidism, and Latent tetanyOsto Polybion D Syrup is used in the treatment of nutritional deficiencies. The detailed uses of Osto Polybion D Syrup are as follows:
• Avoiding Vitamin D Insufficiency: Osto Polybion D Syrup is frequently used to avoid vitamin D insufficiency in people whose vitamin D levels are affected by dietary limitations or inadequate sun exposure.
• Better Absorption of Calcium: It helps the intestines absorb more calcium, which is essential for healthy bones and a strong skeleton.• Immune System Support: Having enough vitamin D may improve the immune system's reaction. The immune system can be strengthened by Osto Polybion D Syrup , particularly during flu season or when there is heightened vulnerability to infections.
• Nutritional Supplement: For people with higher iron needs, such as pregnant women and those following dietary restrictions, Osto Polybion D Syrup can be used as a nutritional supplement.
particularly during flu season or when there is heightened vulnerability to infections.
• Osteoporosis management: Osto Polybion D Syrup is frequently used to help postmenopausal women with osteoporosis by boosting bone density and lowering fracture risk.

Directions for Use

  • Osto Polybion D Syrup can be taken with or without food because food does not impact its effectiveness.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Measure the prescribed dose using a measuring cup and administer it orally.
  • Shake well before use. Avoid using regular household spoons, as they may not measure the dose correctly.

Medicinal Benefits

Osto Polybion D Syrup  consists of three medicines: Elemental Calcium, Vitamin D3, and Cyanocobalamin. Elemental Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation. Vitamin D3 is a steroid hormone produced in the skin when exposed to ultraviolet light or obtained from food sources. It helps maintain blood calcium and phosphorus levels and mineralization of bone. It is used to treat and prevent bone disorders, such as rickets and osteomalacia. Cyanocobalamin is a form of vitamin B12 that helps in the proper functioning of the brain, nerves, and the production of red blood cells. It treats low blood levels of vitamin B12 in people with pernicious anaemia and other conditions like pregnancy, thyroid problems, stomach, and intestinal disorders.

How Osto Polybion D Syrup Works

Osto Polybion D Syrup consists of three medicines: Elemental Calcium, Vitamin D3 (Cholecalciferol), and Cyanocobalamin. Elemental Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation. Vitamin D3 is a steroid hormone produced in the skin when exposed to ultraviolet light or obtained from food sources. It helps maintain blood calcium and phosphorus levels and mineralization of bone. Cyanocobalamin is a form of vitamin B12 that helps in the proper functioning of the brain, nerves, and red blood cells.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Osto Polybion D Syrup

Avoid exceeding the recommended dose as it might cause an overdose. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

Let your doctor know if you are allergic to Osto Polybion D Syrup or its inactive components. Osto Polybion D Syrup is not recommended if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Brief your medical history to the doctor if you have any heart/kidney/liver/blood vessel diseases, and kidney stones before starting Osto Polybion D Syrup .  Pregnant or breastfeeding women should consult their doctor before taking Osto Polybion D Syrup . Drinking alcohol can hinder calcium absorption; therefore, it is advised to limit the alcohol intake while using Osto Polybion D Syrup . Osto Polybion D Syrup is safe to use in children only when advised by the doctor. Do not store Osto Polybion D Syrup above 25°C.

Drug-Drug Interactions

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ColecalciferolCalcifediol
Severe
ColecalciferolParicalcitol
Severe

Drug-Drug Interactions

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ColecalciferolCalcifediol
Severe
How does the drug interact with Osto Polybion D Syrup 200 ml:
The combined use of calcifediol with cholecalciferol can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Osto Polybion D Syrup 200 ml and calcifediol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolParicalcitol
Severe
How does the drug interact with Osto Polybion D Syrup 200 ml:
The combined use of cholecalciferol and paricalcitol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Osto Polybion D Syrup 200 ml and paricalcitol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolCalcitriol
Severe
How does the drug interact with Osto Polybion D Syrup 200 ml:
Co-administration of Cholecalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Osto Polybion D Syrup 200 ml and calcitriol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolErgocalciferol
Severe
How does the drug interact with Osto Polybion D Syrup 200 ml:
The combined use of cholecalciferol and ergocalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Osto Polybion D Syrup 200 ml and ergocalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolAluminium hydroxide
Severe
How does the drug interact with Osto Polybion D Syrup 200 ml:
The combined use of aluminum hydroxide with Osto Polybion D Syrup 200 ml may increase the risk of toxicity.

How to manage the interaction:
Co-administration of Osto Polybion D Syrup 200 ml with Aluminium hydroxide can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like bone pain, muscle weakness, anemia, seizures, or dementia, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ColecalciferolDoxercalciferol
Severe
How does the drug interact with Osto Polybion D Syrup 200 ml:
Cholecalciferol and doxercalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Osto Polybion D Syrup 200 ml and doxercalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolDihydrotachysterol
Severe
How does the drug interact with Osto Polybion D Syrup 200 ml:
Cholecalciferol and dihydrotachysterol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Osto Polybion D Syrup 200 ml and dihydrotachysterol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolSucralfate
Severe
How does the drug interact with Osto Polybion D Syrup 200 ml:
Taking Cholecalciferol together with Sucralfate may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Cholecalciferol and Sucralfate, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Calcium carbonateDigoxin
Severe
How does the drug interact with Osto Polybion D Syrup 200 ml:
Co-administration of Osto Polybion D Syrup 200 ml and Digoxin may increase the calcium levels may increase the effects of Digoxin

How to manage the interaction:
Although there is an interaction, Osto Polybion D Syrup 200 ml can be taken with Digoxin if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
Calcium carbonateRaltegravir
Severe
How does the drug interact with Osto Polybion D Syrup 200 ml:
Co-administration of Osto Polybion D Syrup 200 ml may interfere with the absorption of Raltegravir and reduce its effectiveness.

How to manage the interaction:
Taking Osto Polybion D Syrup 200 ml with Raltegravir should be avoided. Consult the doctor if you have any concerns, the doctor may recommend alternatives that do not interact with raltegravir. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include dairy products like milk, yogurt, cheese, or milk-based custard in your diet.
  • Eat daily a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables.
  • Try Vitamin B complex food sources like milk, cheese, eggs, liver and kidney, chicken, red meat, tuna, mackerel, and salmon, shellfish, oysters, clams, dark green vegetables, such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.
  • Include the best dietary sources of vitamin D, such as fish liver oils and vitamin D–fortified milk.
  • Snack on calcium-rich nuts like Brazil nuts or almonds. 
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Habit Forming

No

Therapeutic Class

NUTRITIONAL SUPPLEMENT
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using Osto Polybion D Syrup .

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Pregnancy

Caution

During pregnancy, use higher doses of Osto Polybion D Syrup than the daily dietary allowance only when the doctor advises. Your doctor will weigh the potential risks and benefits before recommending Osto Polybion D Syrup .

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Breast Feeding

Caution

Consult your doctor before taking Osto Polybion D Syrup if you are breastfeeding. Osto Polybion D Syrup can pass into the breast milk. If Osto Polybion D Syrup is used during breastfeeding, please monitor the serum calcium levels of the mother and the infant.

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Driving

Safe

If you experience any unmanageable side effects while using Osto Polybion D Syrup , do not drive or operate machinery.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Osto Polybion D Syrup . Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.

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Kidney

Caution

It is advised to seek doctor advice before starting Osto Polybion D Syrup if you have kidney diseases like kidney stones or undergoing dialysis.

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Children

Consult your doctor

The doctor will decide the dosage of Osto Polybion D Syrup based on the child's age and weight.

Have a query?

FAQs

Osto Polybion D Syrup belongs to the class of 'Vitamins', primarily used to treat nutritional deficiencies. Osto Polybion D Syrup effectively treats various conditions caused by low calcium levels in the body like Vitamin D deficiency, vitamin B12 deficiency, osteoporosis (weak and brittle bones), hypoparathyroidism, latent tetany, and rickets or osteomalacia (softening or deforming of bones due to lack of calcium).

Osto Polybion D Syrup is a dietary supplement that consists of Elemental Calcium, Cyanocobalamin, and Vitamin D3/Cholecalciferol. When you lack these vitamins in your body, which cannot be recovered even with the food sources, Osto Polybion D Syrup helps in normalizing these deficient levels. Collectively, Osto Polybion D Syrup treats nutritional deficiencies.

Osto Polybion D Syrup can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Osto Polybion D Syrup as a daily supplement if you have any kidney problems or a history of kidney stones.

Osto Polybion D Syrup is used to increase low levels of calcium in the body. Hence it is not advised to use Osto Polybion D Syrup during hypercalcaemia since it causes the overdose of calcium leading to kidney stones and other effects.

Antacids may increase the absorption of Calcium from Osto Polybion D Syrup . Hence it is advised to take Osto Polybion D Syrup two hours before or four hours after taking antacids.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Country of origin

India

Manufacturer/Marketer address

L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India
Other Info - OST0083

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