Tizanidine+aceclofenac
About Tizanidine+aceclofenac
Aceclofenac+tizanidine is a combination medicine used to relieve pain and inflammation in conditions such as arthritis, muscle pain, toothache, joint pain, and headache.
It contains Tizanidine and Aceclofenac, which relax tight muscles, reduce swelling, and ease pain, helping you move more comfortably during daily activities.
Take Aceclofenac+tizanidine exactly as prescribed by your doctor. Nausea, vomiting, stomach pain, heartburn, loss of appetite, or diarrhoea may occur. Consult your doctor if these persist.
Do not use if you are allergic to any ingredients. Consult your doctor before use if pregnant or breastfeeding, and inform them about any other medicines or health conditions.
Uses of Tizanidine+aceclofenac
• Pain Relief: Aceclofenac+tizanidine is used to manage moderate to severe pain, including injuries, post-surgical pain, and various medical conditions.
• Anti-Inflammatory: It helps reduce inflammation associated with conditions like osteoarthritis, rheumatoid arthritis by blocking chemicals in the body that cause swelling.
• Headache: Aceclofenac+tizanidine helps to ease migraine pain and provides relief from symptoms like headaches.
• Menstrual Pain: Aceclofenac+tizanidine provides relief from period pain and cramps, helping to ease the discomfort of dysmenorrhea.
• Postoperative Pain: Aceclofenac+tizanidine can be prescribed to manage pain following surgical procedure as it is a combination of an NSAID and a muscle relaxant to ease post-surgery pain, swelling, and stiffness, supporting a smoother recovery.
Medicinal Benefits
Aceclofenac+tizanidine, when used as prescribed, may provide the following benefits:
For Pain Associated with Musculoskeletal and Joint Disorders:
- Provides relief from moderate to severe pain caused by injuries, joint problems, or muscle strain.
- Minimises headache and migraine-related discomfort.
- Provides relief from menstrual cramps and period-related pain.
- Reduces pain after surgery and supports a comfortable recovery
For Inflammation Associated with Musculoskeletal and Joint Disorders:
- Helps reduce joint and muscle swelling and stiffness.
- Enhances comfort in chronic joint disorders such as arthritis.
- Reduces post-surgical inflammation and muscle tightness.
- Promotes improved movement and daily physical activity.
Directions for Use
- Aceclofenac+tizanidine can be taken with food to avoid stomach upset.
- It is usually taken twice daily or as prescribed by your doctor.
- Swallow Aceclofenac+tizanidine as a whole with a glass of water.
- Do not break, chew, or crush it.
Storage
Side Effects of Tizanidine+aceclofenac
- Nausea
- Vomiting
- Stomach pain
- Diarrhoea
- Loss of appetite
- Heartburn
Drug Warnings
- Do not take Aceclofenac+tizanidine if you are allergic to any of its components.
- Inform your doctor if you have/ had high blood pressure, heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, bypass surgery, heart attack, blood circulation problems, or inflammation of the intestine, high cholesterol, diabetes, asthma, inflammatory bowel disease, liver or kidney problems.
- Consult your doctor if you are pregnant or breastfeeding.
- Aceclofenac+tizanidine may cause drowsiness and dizziness; do not drive if you are not alert.
- Aceclofenac+tizanidine is not recommended for children as safety and effectiveness have not been established.
- Stop taking Aceclofenac+tizanidine and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.
Drug Interactions
Drug-Drug Interactions: Inform your doctor if you are taking any other medicines, as there may be an interaction.
- Antidepressants (Citalopram, Duloxetine)
• Potential effect: May increase the risk of drowsiness, dizziness, and low blood pressure when used together. - Sleeping pills (Zolpidem)
• Potential effect: May cause excessive sleepiness, reduced alertness, and impaired coordination. - Anticonvulsant-fits medicine (Pregabalin)
• Potential effect: May increase sedation, dizziness, and weakness. - Antihistamine-allergy medicine (Diphenhydramine)
• Potential effect: May enhance drowsiness and lower blood pressure when taken together.
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you are suffering from any of these conditions.
- Stomach ulcer or perforation
- Bleeding problems
- Bypass surgery
- Heart attack
- Blood circulation problems
- Heart problems
- Inflammation of the intestines
- Anaemia (low blood)
- kidney problems
- Liver problems
Drug-Drug Interactions Checker List:
Safety Advice

Alcohol
unsafeAvoid consumption of alcohol while taking Aceclofenac+tizanidine as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.

Pregnancy
cautionPlease consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

Breast Feeding
cautionConsult your doctor if you are breastfeeding; your doctor will decide whether Aceclofenac+tizanidine can be taken by breastfeeding mothers or not.

Driving
cautionAceclofenac+tizanidine may cause dizziness. Do not drive or operate machinery unless you are alert.

Liver
cautionDose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

Kidney
cautionDose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

Children
unsafeAceclofenac+tizanidine is not recommended for children as safety and effectiveness are not established.
Habit Forming
Diet & Lifestyle Advise
Exercise:
- Do mild exercises like walking or jogging to keep muscles flexible.
- Stretch gently before and after activity to prevent muscle tightness.
Rest & Recovery:
- Get enough rest and sleep to support muscle healing.
- Avoid overexertion and take breaks during physical activity.
- Change your position every two hours to prevent pressure build-up on your muscles.
Pain Relief Measures:
- Apply warm or cold packs for 15–20 minutes to ease muscle spasms.
- A gentle massage can help relax stiff and sore muscles.
Daily Habits:
- Maintain good posture while sitting or sleeping.
- Avoid sudden movements that may strain muscles.
Hydration:
- Drink plenty of water throughout the day to keep muscles hydrated.
Patients Concern
Disease/Condition Glossary
Pain: A symptom triggered by the nervous system that causes uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalised (affecting the whole body) or localised (affecting a specific body area). Common causes of pain include headaches, muscle strain, cramps, cuts, bone fractures, and arthritis.
Arthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.
FAQs
Aceclofenac+tizanidine is used to treat pain and inflammation associated with musculoskeletal and joint disorders.
Aceclofenac+tizanidine contains Tizanidine and Aceclofenac. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improve muscle movements. Aceclofenac works by blocking the effect of prostaglandins, thereby reducing mild to moderate pain and inflammation.
Aceclofenac+tizanidine is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.
Diarrhoea may be a side effect of Aceclofenac+tizanidine. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Dry mouth could be a side effect of Aceclofenac+tizanidine. Limiting caffeine intake, avoiding smoking and alcohol-containing mouthwashes, drinking water regularly, and chewing sugar-free gum/candy may stimulate saliva production and prevent mouth dryness.
Taking Aceclofenac+tizanidine can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking Aceclofenac+tizanidine if you have gastrointestinal bleeding or other bleeding problems like haemophilia before using Aceclofenac+tizanidine.
Aceclofenac+tizanidine and Hifenac-MR are similar, as they relieve pain and inflammation but differ in their active components.
Yes, Aceclofenac+tizanidine is a painkiller. However, it is not intended for all types of pain. Use it as prescribed to avoid side effects.
You are not recommended to take Aceclofenac+tizanidine with other painkillers, particularly NSAIDs, as it can increase the risk of side effects like stomach irritation or bleeding. If you are allergic to painkillers or NSAIDs, you should avoid using Aceclofenac+tizanidine. Always check with your doctor before taking Aceclofenac+tizanidine with other medicines.
Take Aceclofenac+tizanidine as prescribed by your doctor. Do not adjust the dose without consulting them. If the pain persists, consult your doctor for further guidance.
Aceclofenac+tizanidine contains Aceclofenac and Tizanidine, making it effective for pain relief and muscle relaxation. Zerodol-SP, on the other hand, includes Aceclofenac, Paracetamol, and Serratiopeptidase, which help reduce pain, inflammation, and swelling. Both should be used as directed by a doctor.
Diabetic patients can use Aceclofenac+tizanidine, but it should be taken with caution as it may impact blood sugar levels. Therefore, please consult a doctor before using Aceclofenac+tizanidine to ensure its safety for your condition. Regular monitoring of blood sugar is recommended.
You are recommended to consult a doctor before taking Aceclofenac+tizanidine with paracetamol or other medicines to avoid potential interactions.
Aceclofenac+tizanidine may cause drowsiness, as it is a common side effect. However, please consult a physician if this side effect persists for an extended period.
Yes, the use of Aceclofenac+tizanidine can cause nausea and vomiting. Take it with food or milk, or with antacids, to prevent nausea. Avoid consuming fried or fatty foods with Aceclofenac+tizanidine. If vomiting occurs, drink plenty of water or other fluids by taking small, frequent sips. If vomiting persists, consult your doctor.
You are advised to take Aceclofenac+tizanidine preferably after meals to minimize the risk of stomach discomfort. However, always follow your doctor's instructions.
Aceclofenac+tizanidine usually starts working within 20-30 minutes of taking it, though the onset may vary depending on individual health conditions.
Aceclofenac+tizanidine contains aceclofenac and tizanidine as its active components.
Do not take higher than the recommended dose of Aceclofenac+tizanidine as it can lead to increased side effects. Therefore, do not exceed the recommended dose. If your symptoms worsen, please consult your doctor.
Store Aceclofenac+tizanidine at room temperature in a cool and dry place as advised on the label. Protect from light and moisture. Keep it out of reach of children.
Aceclofenac+tizanidine is safe when used as per the dose and duration advised by a doctor.
Aceclofenac+tizanidine is contraindicated in individuals with known allergies to its ingredients, or patients with high blood pressure, heart problems, stomach ulcers, bleeding disorders, inflammatory bowel disease, high cholesterol, diabetes, asthma, or liver and kidney issues. Aceclofenac+tizanidine is not recommended for children, and you should consult your doctor if you are pregnant or breastfeeding.
You are recommended not to stop taking Aceclofenac+tizanidine without consulting your doctor as stopping it suddenly can cause adverse effects. Therefore, continue taking Aceclofenac+tizanidine for the duration prescribed and if you experience any difficulty while taking Aceclofenac+tizanidine, consult your doctor so that the dose may be reduced gradually.
Take Aceclofenac+tizanidine as directed by your doctor. Swallow Aceclofenac+tizanidine whole with a glass of water; do not crush, chew, or break it.
You are recommended to avoid alcohol while taking Aceclofenac+tizanidine, as it may cause excessive drowsiness and increase the risk of stomach bleeding. Please consult the doctor if you have any concerns.
Pregnant women should consult a doctor before taking Aceclofenac+tizanidine. Your doctor prescribes Aceclofenac+tizanidine only when the benefits outweigh the risks. Do not self-medicate.
If you miss a dose of Aceclofenac+tizanidine, take it as soon as you remember and if it is the time for the next dose, skip the missed dose and continue with the regular dose. Avoid taking double dose to make up for the missed one.
Aceclofenac+tizanidine may cause side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, and heartburn. These do not require any medical treatment as they will gradually reduce over time. Consult a doctor if these side effects persist for longer durations.


