ADAPALENE+BENZOYL PEROXIDE belongs to the class of dermatological preparations called ‘antiacne’ used to treat acne (pimples) and remove the skin's upper dead layer. Acne is a common skin condition and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feeds on sebum (natural oil produced by skin) causing redness and swelling.
ADAPALENE+BENZOYL PEROXIDE is a combination of two drugs: Adapalene (retinoids) and Benzoyl peroxide (keratolytic agent). Adapalene belongs to the retinoid class (human-made vitamin A) which works by loosening the cells on the skin’s surface and unblocks pores by reducing oil production in the skin. Thereby, decreases pimples, whiteheads, and blackheads. Benzoyl peroxide is a keratolytic agent that breaks down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that cause acne.
Take ADAPALENE+BENZOYL PEROXIDE as prescribed. ADAPALENE+BENZOYL PEROXIDE is only for external use. Avoid contact of ADAPALENE+BENZOYL PEROXIDE with nose, ears, mouth, or eyes. In case ADAPALENE+BENZOYL PEROXIDE comes in contact with these areas accidentally, rinse with warm water thoroughly. Your doctor will advise you how often you take ADAPALENE+BENZOYL PEROXIDE based on your medical condition. You may experience dry skin, scaling, local skin rash, irritation, redness, or burning sensation of the skin in some cases. Most of these side effects of ADAPALENE+BENZOYL PEROXIDE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are known to be allergic to ADAPALENE+BENZOYL PEROXIDE or any other medicines, please tell your doctor. Do not apply ADAPALENE+BENZOYL PEROXIDE on cuts, open wounds, scrapes, sunburned, windburned, chapped, dry, or irritated skin. Avoid exposure to tanning beds or sunlight while using ADAPALENE+BENZOYL PEROXIDE as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking ADAPALENE+BENZOYL PEROXIDE. Do not apply ADAPALENE+BENZOYL PEROXIDE in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as irritation, scaling, or redness of the skin. If you have eczema (itchy, swollen, rough, and cracked skin) or sunburned skin, please inform your doctor before taking ADAPALENE+BENZOYL PEROXIDE.
Acne (pimples)
ADAPALENE+BENZOYL PEROXIDE is a combination of two drugs: Adapalene and Benzoyl peroxide used to treat acne (pimples). Adapalene is a retinoid (human-made vitamin A) that loosens the cells on the skin’s surface and unblocks pores by reducing oil production in the skin. Thereby, decreases pimples, spots, whiteheads, and blackheads. Also, it increases the production of new skin cells and helps in natural exfoliation (removal of dead skin cells) of the outer layers of the skin. Adapalene has an anti-inflammatory effect and thus reduces irritation and soreness. Benzoyl peroxide is a keratolytic agent that breaks down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that cause acne.
If you are known to be allergic to ADAPALENE+BENZOYL PEROXIDE or any other medicines, please tell your doctor. Do not apply ADAPALENE+BENZOYL PEROXIDE on cuts, open wounds, scrapes, sunburned, windburned, chapped, dry, or irritated skin. ADAPALENE+BENZOYL PEROXIDE is only for external use. Do not swallow ADAPALENE+BENZOYL PEROXIDE. In case of accidental swallowing, please consult a doctor. Avoid contact of ADAPALENE+BENZOYL PEROXIDE with nose, ears, mouth, or eyes. In case ADAPALENE+BENZOYL PEROXIDE comes in contact with these areas accidentally, rinse with warm water thoroughly. Avoid exposure to tanning beds or sunlight while using ADAPALENE+BENZOYL PEROXIDE as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking ADAPALENE+BENZOYL PEROXIDE. Do not apply ADAPALENE+BENZOYL PEROXIDE in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as irritation, scaling, or redness of the skin. If you have eczema (itchy, swollen, rough, and cracked skin) or sunburned skin, please inform your doctor before taking ADAPALENE+BENZOYL PEROXIDE.
Drug-Drug Interaction: ADAPALENE+BENZOYL PEROXIDE may interact with vitamin A-related drugs known as retinoids (isotretinoin, tretinoin, bexarotene, trifarotene), photosensitizing agents (aminolevulinic acid, methoxsalen, porfimer, verteporfin), antibiotics (dapsone), sensitizer (methyl aminolevulinate), keratolytic agents (salicylic acid, sulfur), antiseptic (resorcinol).
Drug- Food Interaction: No interactions found.
Drug-Disease Interaction: If you have eczema (itchy, swollen, rough and cracked skin) or sunburned skin, please inform your doctor before taking ADAPALENE+BENZOYL PEROXIDE.
Interaction of ADAPALENE+BENZOYL PEROXIDE with alcohol is unknown. Please consult a doctor before consuming alcohol while using ADAPALENE+BENZOYL PEROXIDE.
ADAPALENE+BENZOYL PEROXIDE is a category C pregnancy drug and is usually not recommended for pregnant women. Please consult a doctor if you are pregnant.
It is unknown whether ADAPALENE+BENZOYL PEROXIDE is excreted in human milk. Therefore, ADAPALENE+BENZOYL PEROXIDE is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. However, do not apply ADAPALENE+BENZOYL PEROXIDE on the chest area to avoid the contact of ADAPALENE+BENZOYL PEROXIDE with the baby.
ADAPALENE+BENZOYL PEROXIDE usually does not affect your ability to drive or operate machinery.
If you have any concerns regarding the use of ADAPALENE+BENZOYL PEROXIDE in patients with Liver problems, please consult a doctor.
If you have any concerns regarding the use of ADAPALENE+BENZOYL PEROXIDE in patients with kidney problems, please consult a doctor.
ADAPALENE+BENZOYL PEROXIDE is not recommended for children below 9 years as the safety and effectiveness were not established.
Acne (pimples): It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages but is most common among teenagers. Acne symptoms include pus-filled pimples, uninflamed (not swollen) blackheads, red, large, and tender bumps. The treatment for acne includes certain creams, cleansers, and antibiotics.