Alfuzosin+solifenacin
About Alfuzosin+solifenacin
Alfuzosin+solifenacin is used to treat benign prostatic hyperplasia (overgrowth of the prostate gland, a gland situated between the bladder and penis). Benign prostatic hyperplasia is a common illness as men get older.
Alfuzosin+solifenacin is a combination of Alfuzosin (alpha-blockers) and Solifenacin (antimuscarinic), which work by relaxing the muscle around the bladder and prostate gland so urine is passed more easily. This prevents frequent, urgent or uncontrolled urination.
Take Alfuzosin+solifenacin as advised by your doctor. Alfuzosin+solifenacin may cause side effects such as dizziness, headache, fatigue, dry mouth, blurred vision, constipation, and flushing (a sensation of warmth in the face, ears, neck, and trunk). If any of the side effects persist, reach out to your doctor.
Inform your doctor if you are allergic to any of the components in Alfuzosin+solifenacin. Women or children should not take Alfuzosin+solifenacin. Avoid intake of Alfuzosin+solifenacin with antihypertensive drugs, as it may lead to a sudden drop in blood pressure, causing unpleasant effects.
Uses of Alfuzosin+solifenacin
Medicinal Benefits
- Alleviates benign prostatic hyperplasia (BPH) symptoms.
- Increases urine flow by calming the muscles in the neck and prostate.
- Decreases the frequency and urgency of urination.
- Aids in the management of urge incontinence, or unexpected urine leaking.
- Reduces nighttime urination.
- Lessens the sensation of an unfinished bladder emptying.
- Improves comfort and bladder control.
Directions for Use
- Take Alfuzosin+solifenacin with food or as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow it as a whole with a glass of water.
- Do not crush, chew or break it.
Storage
Side Effects of Alfuzosin+solifenacin
- Dizziness
- Headache
- Tiredness
- Dry mouth
- Blurred vision
- Constipation
- Flushing (sense of warmth in the face, ears, neck and trunk)
Medicines Containing this Salt
View AllDrug Warnings
- Do not take Alfuzosin+solifenacin if you are allergic to any of its ingredients.
- Women or children should not take Alfuzosin+solifenacin.
- If you take Alfuzosin+solifenacin with any antihypertensive medicine, your blood pressure could suddenly drop, which may be serious. So avoid intake of Alfuzosin+solifenacin with antihypertensive drugs.
- You are advised not to drive or operate heavy machinery after taking Alfuzosin+solifenacin, as it may cause dizziness.
- Avoid consuming alcohol along with Alfuzosin+solifenacin as it could lead to increased dizziness and drowsiness.
- Let your doctor know if you are taking any other medicines.
Drug Interactions
Drug-Drug Interaction: Inform your doctor if you are taking any of these medicines, as there may be an interaction.
- Medicines used to treat high blood pressure (prazosin, diltiazem)
• Potential effect: May cause low blood pressure. - Anti-epilepsy medicines (Carbamazepine, phenytoin)
• Potential effect: May reduce the effectiveness of these medicines. - Antifungals (itraconazole, ketoconazole)
• Potential effect: May increase the risk of side effects. - Antibiotics (clarithromycin)
• Potential effect: May increase the risk of side effects.
Drug-Food Interaction: Alfuzosin+solifenacin may interact with grapefruit juice, alcohol, and tobacco. This may cause more side effects than usual. So, Alfuzosin+solifenacin should not be taken along with them.
Drug-Disease Interaction: Inform your doctor if you have a history of the following conditions before taking Alfuzosin+solifenacin, as it may worsen your condition or cause complications.
- Heart problems
- Low blood pressure
- Kidney or liver disease
- Certain eye diseases, loss of vision due to loss of blood flow to the optic (eye) nerve
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionYou are advised not to consume alcohol while taking Alfuzosin+solifenacin as it makes you pee more and can irritate your bladder, and also increases dizziness and lowers blood pressure.
Pregnancy
unsafeWomen should not use Alfuzosin+solifenacin as it is used to treat benign prostatic hyperplasia (BPH) in men only.
Breast Feeding
unsafeWomen should not use Alfuzosin+solifenacin as it is used to treat benign prostatic hyperplasia (BPH) in men only.
Driving
cautionAlfuzosin+solifenacin may cause dizziness. Therefore, you are advised to drive and operate machinery only if you are alert.
Liver
cautionAlfuzosin+solifenacin should be used with caution in patients with liver disease. The dose adjustment may be needed in such patients.
Kidney
cautionAlfuzosin+solifenacin should be used with caution in patients with kidney disease. The dose adjustment may be needed in such patients.
Children
unsafeAlfuzosin+solifenacin is not recommended for children. The safety and effectiveness of Alfuzosin+solifenacin have not been established in children due to limited testing of this drug on children by competent authorities worldwide.
Habit Forming
Diet & Lifestyle Advise
Healthy eating habits:
- Avoid excessive caffeine (tea, coffee, and cola) as it may make you urinate more frequently.
- If highly acidic and spicy foods cause bladder discomfort, cut back on them.
- To lessen the strain on the bladder, eat balanced meals and maintain a healthy weight.
Lifestyle changes:
- To enhance bladder control, engage in bladder training exercises.
- Regularly perform Kegel exercises to strengthen your pelvic floor muscles.
- To cut down on nighttime urination, limit the amount of fluids you consume before bed.
- Avoid alcohol and caffeine, as these can irritate the bladder.
Patients Concern
Disease/Condition Glossary
Benign Prostatic Hyperplasia (BPH): It is an enlargement of the prostate gland. The prostate is a small, muscular gland in the male reproductive system. It is a common condition as men get older (50-60 years). It occurs when the cells of the prostate gland begin to multiply. In an enlarged prostate gland, the bladder wall becomes thicker, and the bladder may weaken and lose the ability to empty fully, leaving some urine in the bladder. Symptoms of BPH include frequent or urgent need to urinate, nocturia (increased frequency of urination at night), difficulty starting urination, inability to empty the bladder, painful urination, and blood in the urine.
FAQs
Alfuzosin+solifenacin is used to treat benign prostatic hyperplasia (overgrowth of the prostate gland, a gland situated between the bladder and penis).
Alfuzosin+solifenacin contains Alfuzosin and Solifenacin. It works by relaxing the muscle around the bladder and prostate gland so urine is passed more easily. This prevents frequent, urgent or uncontrolled urination.
Yes, in some cases, sexual problems (like decreased sexual interest/ability/libido, ejaculation problems, decreased sperm/semen amount), testes pain/swelling, increased breast size, or breast tenderness in the male might occur. Sexual problems in a male may continue even after stopping the intake of Alfuzosin+solifenacin. If you have any concerns, talk to your doctor promptly.
Alfuzosin+solifenacin is not recommended for men below the age of 18, childbearing women, and patients with known allergy to any of the components of Alfuzosin+solifenacin.
No, Alfuzosin+solifenacin should not be taken along with blood-pressure-lowering medicines. Alfuzosin+solifenacin may cause a sudden drop in your blood pressure, which could lead to dizziness or fainting. Therefore, if Alfuzosin+solifenacin is taken along with blood pressure-lowering medicines, it could lead to a severe decrease in blood pressure, which could be lethal.
Alfuzosin+solifenacin is usually taken orally after a meal with a glass of water. To get the most benefit, take it regularly at the same time each day or as directed by the physician.
Alfuzosin+solifenacin may cause side effects such as dizziness, headache, fatigue, dry mouth, blurred vision, constipation, and flushing (a sensation of warmth in the face, ears, neck, and trunk). If any of the side effects persist, reach out to your doctor.

