ALOGLIPTIN+METFORMIN belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus in adults. Type-2 diabetes mellitus is also known as non-insulin-dependent diabetes mellitus or adult-onset diabetes. It is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.
ALOGLIPTIN+METFORMIN contains Alogliptin and Metformin. Alogliptin works by increasing the levels of insulin in the body post-meal and decreasing the amount of sugar in the body. Metformin works by lowering the amount of sugar made in the liver and helps insulin to work more effectively. Together, ALOGLIPTIN+METFORMIN helps control blood sugar levels.
You are advised to take ALOGLIPTIN+METFORMIN for the prescribed period. In some cases, ALOGLIPTIN+METFORMIN may cause common side effects such as stomach ache, diarrhoea, loss of appetite, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to consult your doctor if the side effects persist or worsen.
ALOGLIPTIN+METFORMIN is not recommended if you are pregnant or breastfeeding and in children below 18 years. Avoid excessive alcohol consumption while taking ALOGLIPTIN+METFORMIN as it might increase the risk of lactic acidosis. Keep your doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.
Type-2 diabetes mellitus
ALOGLIPTIN+METFORMIN belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus in adults. ALOGLIPTIN+METFORMIN contains Alogliptin and Metformin. Alogliptin belongs to a group of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors) which works by increasing the levels of insulin in the body post-meal and decreasing the amount of sugar in the body. Metformin belongs to a group of medicines called biguanides that works by lowering the amount of sugar made in the liver and helping insulin to work more effectively. Together, ALOGLIPTIN+METFORMIN helps control blood sugar levels.
Do not take ALOGLIPTIN+METFORMIN if you are allergic to any of its components, if you have severely reduced kidney function, uncontrolled diabetes, severe hypoglycaemia, ketoacidosis (excess blood acid), severe infection, serious dehydration, severe circulatory problems, severe breathing difficulties, liver disease, if you had a recent heart attack or if you consume alcohol excessively. Inform your doctor if you have type 1 diabetes, pancreatic disease, or skin blisters. ALOGLIPTIN+METFORMIN is not recommended if you are pregnant or breastfeeding and in children below 18 years. ALOGLIPTIN+METFORMIN may cause a very serious side effect called lactic acidosis, especially if your kidneys are not working properly. The risk of developing lactic acidosis increases with uncontrolled diabetes, prolonged fasting, serious infections, dehydration, alcohol intake, liver problems or severe heart problems. Consult your doctor if you experience symptoms of lactic acidosis such as stomach ache, vomiting, muscle cramps, severe tiredness, difficulty breathing, reduced body temperature or heartbeat.
Drug-Drug Interactions: Inform your doctor if you are taking corticosteroids (hydrocortisone, prednisolone), antacids (cimetidine), bronchodilators, diuretics, pain killers (ibuprofen, celecoxib), anti-hypertensives (ACE inhibitors, angiotensin II receptor antagonists), and medicines containing alcohol.
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have severely reduced kidney function, uncontrolled diabetes, severe hypoglycaemia, ketoacidosis (excess blood acid), severe infection, serious dehydration, severe circulatory problems, severe breathing difficulties, or liver disease.
Avoid excessive alcohol consumption while taking ALOGLIPTIN+METFORMIN as it may increase the risk of lactic acidosis.
ALOGLIPTIN+METFORMIN is not recommended in pregnancy as there are no adequate or well-controlled studies on pregnant women.
ALOGLIPTIN+METFORMIN is not recommended during breastfeeding.
ALOGLIPTIN+METFORMIN may cause hypoglycemia; hence, avoid driving or operating machines if you experience the symptoms of hypoglycemia.
If you have liver problems, inform your doctor. ALOGLIPTIN+METFORMIN is not recommended in patients with liver problems.
Do not take ALOGLIPTIN+METFORMIN if you have increased creatinine levels. Please consult your doctor if you have kidney impairment or any concerns regarding this. Dose adjustment may be needed.
ALOGLIPTIN+METFORMIN is not recommended for children below 18 years due to a lack of data.
Type-2 diabetes mellitus: It is also known as non-insulin-dependent diabetes. It is a chronic or lifelong disease that keeps the body from utilizing insulin properly. People with type 2 diabetes either do not produce enough insulin, or the insulin produced cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes; hence it is also known as adult-onset diabetes. Type 2 diabetes symptoms include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.