ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE is indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms of neuropathic pain include burning or shooting pain followed by tingling and numbness (loss of sensation). Neuropathic pain can be caused due to amputation of limbs, diabetic neuropathy (nerve damage due to excess blood sugar level), excessive alcohol intake (alcoholism), and cancer treatment via chemotherapy.
ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE is a combination of five drugs: Pregabalin, Mecobalamin, Alpha-lipoic acid, Pyridoxine-5-phosphate, and Calcium-L-5-Methyltetrahydrofolate. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Mecobalamin and Pyridoxine-5-phosphate help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and the brain. Calcium-L-5-Methyltetrahydrofolate helps in delivering essential nutrients to the nerves. Together, ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE provides relief from neuropathic pain.
Use ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE as suggested by your doctor. In some cases, you may experience certain common side-effects, such as dizziness, sleepiness, tiredness, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Consult your doctor before starting ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE if you are pregnant or breastfeeding. ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE as it could lead to increased dizziness and sleepiness. ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE is not recommended for children as safety and effectiveness have not been established. Let your doctor know if you are taking any other medicines, including vitamins and herbal supplements.
Neuropathic pain.
ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE contains Pregabalin (anti-convulsant or antiepileptic), Mecobalamin (vitamin B12), Alpha-lipoic acid (antioxidant), Pyridoxine-5-phosphate (vitamin B6), and Calcium-L-5-Methyltetrahydrofolate. ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE is used to treat neuropathic pain. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Mecobalamin and Pyridoxine-5-phosphate help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Calcium-L-5-Methyltetrahydrofolate helps in providing essential nutrients to the nerves. Together, ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE helps in providing relief from neuropathic pain.
Do not take ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE if you are allergic to any of its contents. Inform your doctor before taking ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE if you have/had heart problems or bipolar syndrome. Please do not stop taking ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE without consulting your doctor as it could cause withdrawal symptoms. Do not take ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE if you are pregnant or breastfeeding unless prescribed by the doctor. ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE as it could lead to increased dizziness and sleepiness. ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE is not recommended for children as safety and effectiveness have not been established. Consult your doctor immediately if you experience suicidal tendencies.
Drug-Drug Interaction: ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE may have interaction with antidepressants (amitriptyline), pain killer (codeine, tramadol), anti-convulsant (gabapentin), anti-anxiety (diazepam), anti-diabetic (metformin), immunosuppressant (methotrexate), anti-rheumatoid (sulfasalazine), antibiotic (chloramphenicol), anti-cancer (altretamine), and anti-Parkinson’s (levodopa).
Drug-Food Interaction: Avoid consumption of alcohol while taking ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE as it might cause increased dizziness and sleepiness.
Drug-Disease Interaction: ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE may have interactions with disease conditions such as angioedema, creatine kinase elevations, peripheral oedema, malabsorption, and anaemia.
Avoid consumption of alcohol while taking ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE as it may increase dizziness and sleepiness.
Avoid taking ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.
Consult your doctor before taking ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE; your doctor will decide whether ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE can be taken by breastfeeding mothers or not.
ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE may cause drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
ALPHA LIPOIC ACID+CALCIUM L 5 METHYLTETRAHYDROFOLATE+MECOBALAMIN+PREGABALIN+PYRIDOXAL 5 PHOSPHATE is not recommended for children as safety and efficacy have not been established.
Neuropathic pain: It is a nervous disorder that occurs due to nerve damage caused by chronic progressive nerve disease, limb amputation, diabetes, or due to infection or injury. The pain could be intermittent or continuous, felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of senses is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain that is not triggered by an injury, the body sends the pain signals unpromptedly. Symptoms include spontaneous, un-triggered pain, unpleasant feeling, shooting, burning, or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).