Do not use AMLODIPINE+INDAPAMIDE if you are allergic to any of its components. Let your doctor know if you have any history of severe kidney or liver diseases, low potassium levels (hypokalaemia), chest pain (angina), poor blood circulation or controlled heart failure, first-degree heart block, diabetes, thyrotoxicosis (a condition caused by an overactive thyroid gland), liver problems and adrenal gland diseases. Let your doctor know if you have anuria (kidneys aren't producing urine), fluid or electrolyte imbalance, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), gout, abnormal heart rhythms, thyroid disorders or asthma. Consult your doctor if you are pregnant or breastfeeding. AMLODIPINE+INDAPAMIDE can increase the chances of light-headedness, so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness. AMLODIPINE+INDAPAMIDE is not recommended in people less than 18 years of age.

Drug-Drug Interaction: AMLODIPINE+INDAPAMIDE may interact with other diuretic medications (hydrochlorothiazide, furosemide, torsemide), anti-hypertensive drugs (chlorthalidone, ramipril, metoprolol, lisinopril,  candesartan, baclofen, levodopa, clonidine), drugs treating mental illness (alprazolam, risperidone, amisulpride, pimozide), painkillers (ibuprofen, naproxen), anti-depressants (lithium, duloxetine), Vitamins (vitamin D, cholecalciferol (vitamin D3)), heart-related drugs (amiodarone, digoxin, sotalol), diabetic drugs (insulin glargine, metformin), drugs treating stomach acid (esomeprazole), fits medicine (clonazepam), pain medicine (oxycodone), corticosteroids (prednisone), drugs treating impotence (sildenafil), and multivitamin/minerals.

Drug-Food Interaction: AMLODIPINE+INDAPAMIDE may interact or may have decreased effect when used with alcohol and large amounts of orange juice.

Drug-Disease Interaction: Let your doctor know if you have any severe kidney or liver diseases, low potassium levels (hypokalaemia), chest pain (angina), poor blood circulation or controlled heart failure, first-degree heart block, diabetes, thyrotoxicosis (a condition caused by an overactive thyroid gland), liver problems, adrenal gland diseases, anuria (kidneys aren't producing urine), fluid or electrolyte imbalance, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), gout, abnormal heart rhythms, thyroid disorders or asthma.

• Keep your weight under control with a body mass index (BMI) between 19.5 and 24.9.
• Quit smoking to lower the risk of heart disease. 
• Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress.
• Monitor your blood pressure daily, and if you notice any fluctuations frequently, please get in touch with your doctor immediately.
• Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil that help in lowering your elevated blood pressure.

• Monitor your blood pressure regularly and seek medical advice if you notice any drastic fluctuations.
• Let your doctor know if you are advised for any blood examinations as diuretics like Indapamide can cause changes in the laboratory parameters like low potassium levels in the blood, low sodium in the blood, low blood pressure, increase in uric acid, increase in blood glucose levels in diabetic patients, increase in calcium levels in the blood, and increase in the liver enzyme levels. 
• Let your anaesthetist or medical staff know that you are taking AMLODIPINE+INDAPAMIDE since AMLODIPINE+INDAPAMIDE can lower blood pressure levels when certain anaesthetic medications are given during any operation or surgery.
• Athletes should be aware that Indapamide in AMLODIPINE+INDAPAMIDE gives a positive reaction in doping tests.