APROTININ belongs to the group of medicines called anti-fibrinolytic agents used to reduce bleeding during and after heart surgery. It is also used to lower the need for blood transfusion during and after heart surgery.
APROTININ contains aprotinin that prevents bleeding by inhibiting the activation of coagulants.
APROTININ will be administered by a healthcare professional; do not self-administer. In some cases, APROTININ may cause chest pain, stomach upset, fast heartbeat and injection site reactions. You are advised to talk to the doctor if you experience any side effects.
Consult the doctor if you are pregnant or breastfeeding. APROTININ is not recommended for children below 18 years as the safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.
Reduce bleeding during and after surgery.
APROTININ contains aprotinin that belongs to the group of medicines called anti-fibrinolytic agents used to reduce bleeding during and after heart surgery. It also lowers the need for blood transfusion during and after heart surgery. APROTININ inhibits the activation of coagulants. Thereby, APROTININ prevents bleeding.
Do not use APROTININ if you are allergic to any of its components or if a positive aprotinin-specific IgG antibody test is available, indicating an increased risk of an allergic reaction to aprotinin. Inform the doctor if you have kidney problems or have/suspect you have received aprotinin or aprotinin-containing fibrin sealants in the last 12 months. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you have any health condition or if you are taking any medications, including herbal products or vitamin/mineral supplements.
Drug-Drug Interactions: Inform the doctor if you take medicines used to dissolve blood clots (streptokinase, urokinase, alteplase) or antibiotics (aminoglycosides).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform the doctor if you have kidney problems.
It is not known if APROTININ interacts with alcohol. Please consult your doctor.
If you are pregnant, inform your doctor before receiving APROTININ. The doctor will prescribe the medicine only if the benefits outweigh the risks.
If you are a nursing mother, inform your doctor before receiving APROTININ. The doctor will prescribe the medicine only if the benefits outweigh the risks.
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If you have a history of liver disease, inform your doctor before receiving APROTININ.
If you have a history of kidney disease, inform your doctor before receiving APROTININ. It should be used only in patients with kidney problems if the doctor/surgeon thinks the benefits outweigh the risks.
APROTININ is not recommended for children below 18 years as the safety and efficacy have not been established.
APROTININ may affect certain lab tests. If you are undergoing any lab tests, inform the doctor that you are on treatment with APROTININ.
Perioperative blood management: It is a process to stop or prevent bleeding during surgery and avoid or minimise blood transfusion.